トップ研究者を探すStimulating the host innate immune response to fight the early stages of malaria infection

Stimulating the host innate immune response to fight the early stages of malaria infection

KAKEN 科学研究費助成事業データベース で見る
研究課題番号 KAKENHI-PROJECT-16K21233
研究種目 若手研究(B)
研究分野 生物系
医歯薬学
基礎医学
寄生虫学(含衛生動物学)
生物系
医歯薬学
基礎医学
免疫学
研究機関 長崎大学
代表研究者 カレトン リチャード
研究期間 開始年月日 2016/4/1
研究期間 終了年度 2017
研究ステータス 完了 (2017/4/1)
配分額(合計) 4,160,000 (直接経費 :3,200,000、間接経費 :960,000)
配分額(履歴) 2017年度:1,560,000 (直接経費 :1,200,000、間接経費 :360,000)
2016年度:2,600,000 (直接経費 :2,000,000、間接経費 :600,000)
キーワード Malaria
Pam2Cys
vaccine
antimalarial drug
malaria

研究成果

[雑誌論文] An assay for the identification of Plasmodium simium infection for diagnosis of zoonotic malaria in the Brazilian Atlantic Forest

Alvarenga DA, Culleton R, Pina-Costa Ad, Rodrigues D, Junior CB, Silva S, Nunes AJ, J Souza jr JCd, Hirano Z, Moreira ZB, Pissinatti A, Abreu F, Areas AL, Lourenco-de-Oliveira R, Zalis MG, Brasil P, Ferreira-da-Cruz MdF, Daniel-Ribeiro CT, Alves de Brito CF 2018

[雑誌論文] Outbreak of human malaria caused by Plasmodium simium in the Atlantic Forest in Rio de Janeiro: a molecular epidemiological investigation

Brasil P, Zalis M G, de Pina-Costa A, Siqueira AM, Bianco Junior C, Silva S, Areas ALL, Pelajo-Machado M, de Alvarenga DAM, Santelli ACFdS, Albuquerque HG, Cravo P, de Abreu FVS, Peterka CL, Zanini GM, Suarez-Mutis MC, Pissinatti A, Lourenco-de-Oliveira R, Brito CFAd, Ferreira-da-Cruz MdF, Culleton R, Daniel-Ribeiro CT 2017

[雑誌論文] Emergence of Indigenous Artemisinin Resistant Plasmodium falciparum in Africa

Lu F, Culleton R, Zhang M, Ramaprasad A, von Seidlein L, Zhou H, Zhu G, Tang J, Liu Y, Wang W, Cao Y, Xu S, Gu Y, Li J, Zhang C, Gao Q, Menard D, Pain A, Yang H, Zhang Q & Cao J. 2017

[雑誌論文] Non-human Primate Malaria Parasites: Out of the forest and into the laboratory

Martinelli A & Culleton R 2017

[学会発表] Phenotypic, Genotypic, and Transcriptomic Characterisation of the Plasmodium vinckei clade of Rodent Malaria Parasites

Richard Culleton 2017

[雑誌論文] Return of chloroquine sensitivity to Africa? Surveillance of African Plasmodium falciparum chloroquine resistance through malaria imported to China

Lu F、Zhang M、Culleton RL、Xu S、Tang J、Zhou H、Zhu G、Gu Y、Zhang C、Liu Y、Wang W、Cao Y、Li J、He X、Cao J、Gao Q 2017

[学会発表] Malaria: A Deadly Zoonosis

Richard Culleton 2017

[雑誌論文] Artemisinin-Resistant Plasmodium falciparum in Africa

Lu F, Culleton R, Cao J 2017

[学会発表] Genetic analysis of Plasmodium malariae and Plasmodium ovale from asymptomatic adolescents in South-East Nigeria

Richard Culleton 2017

[学会発表] Genetic analysis of Plasmodium malariae and Plasmodium ovale from asymptomatic adolescents in South-East Nigeria

Richard Culleton 2017

[雑誌論文] Plasmodium knowlesi and human malaria parasites in Khan Phu, Vietnam: Gametocyte production in humans and frequent co-infection of mosquitoes.

Maeno Y, Culleton R, Quang NT, Kawai S, Marchand RP, NakazawaS 2017

[学会発表] Pam2Cys as a novel immunochemoprophylactic and immunochemotherapeutic in malaria

Richard Culleton 2016

[雑誌論文] Genome-scale comparison of expanded gene families in Plasmodium ovale wallikeri and Plasmodium ovale curtisi with Plasmodium malariae and with other Plasmodium species.

Ansari HA, Templeton JT, Subudhi AK, Ramaprasad A, Tang J, Lu J, Naeem R, Oguike MC, Benavente ED, Clark TG, Sutherland CJ, Barnwell JW, Culleton R*, Cao J* and Pain A* 2016

[学会発表] Genome-scale comparison of expanded gene families in Plasmodium ovale wallikeri and Plasmodium ovale curtisi with Plasmodium malariae and with other Plasmodium species

Richard Culleton 2016

[雑誌論文] Genetic Diversity And Population Structure Of Plasmodium Falciparum In Lake Victoria Islands, A Region Of Intense Transmission

Mulenge FM, Hunja CW, Magiri E, Culleton R, Kaneko A, Aman RA 2016