トップ研究者を探す多剤耐性遺伝子の環境中残存機構と人への暴露リスク評価

多剤耐性遺伝子の環境中残存機構と人への暴露リスク評価

KAKEN 科学研究費助成事業データベース で見る
研究課題番号 KAKENHI-PROJECT-16H01782
研究種目 基盤研究(A)
研究分野 総合系
環境学
環境解析学
環境影響評価
研究機関 愛媛大学
代表研究者 鈴木 聡
研究分担者 渡部 徹
研究分担者 丸山 史人
研究分担者 野村 暢彦
研究期間 開始年月日 2016/4/1
研究期間 終了年度 2020
研究ステータス 完了 (2020/4/1)
配分額(合計) 40,560,000 (直接経費 :31,200,000、間接経費 :9,360,000)
配分額(履歴) 2019年度:7,930,000 (直接経費 :6,100,000、間接経費 :1,830,000)
2018年度:7,930,000 (直接経費 :6,100,000、間接経費 :1,830,000)
2017年度:7,930,000 (直接経費 :6,100,000、間接経費 :1,830,000)
2016年度:8,840,000 (直接経費 :6,800,000、間接経費 :2,040,000)
キーワード 薬剤耐性遺伝子
環境微生物
抗生物質
暴露リスク
バイオフィルム
メンブレンベシクル
遺伝子残存
遺伝子水平伝播
メタゲノム
リスク評価

研究成果

[学会発表] 環境細菌のもつ薬剤耐性遺伝子のヒト病原体への伝播リスク

鈴木 聡 2020

[雑誌論文] 沿岸海域における薬剤耐性菌・耐性遺伝子の潜伏

鈴木 聡 2020

[雑誌論文] Drug resistant bacteria in our oceans: Where did they come from and where will they go?

Suzuki, S. 2019

[学会発表] 飢餓状態の海洋細菌のプロテアーゼ産生に及ぼす有機物の効果

新藤紗音・大林由美子・鈴木 聡 2019

[学会発表] Ecological perspective of dissemination of antibiotic resistance genes in marine environment

Suzuki, S. 2019

[学会発表] 養殖場由来多剤耐性伝達性プラスミドのトランスポゾンを介する染色体への組み込み

野中里佐・丸山史人・杉本侑大・鈴木 聡・増田道明・矢野大和 2019

[雑誌論文] Understanding human health risks caused by antibiotic resistant bacteria (ARB) and antibiotic resistance genes (ARG) in water environments: Current knowledge and questions to be answered.

Anomasiri, M., Sano D., Suzuki, S. 2019

[雑誌論文] Anthropogenic impacts on sulfonamide residues and sulfonamide resistant bacteria and genes in Larut and Sangga Besar River, Perak.

Lye, Y.L., Bong, C.W., Lee, C.W., Zhang, R.J., Zhang, G., Suzuki, S., Chai, L.C. 2019

[学会発表] 薬剤耐性遺伝子の水圏環境での動態

鈴木 聡 2019

[学会発表] Environmental dimension of macrolide resistance genes in Taiwanese aquatic environment

Suzuki, S. 2019

[雑誌論文] Conjugative Gene Transfer between Nourished and Starved Cells of <i>Photobacterium damselae</i> ssp. <i>damselae</i> and <i>Escherichia coli</i>

Kohyama, Y., Suzuki, S. 2019

[雑誌論文] Drug resistant bacteria in our oceans: Where did they come from and where will they go?

Suzuki, S. 2019

[学会発表] Interactive dissemination of antibiotic resistance genes between clinical sites and marine environment

Suzuki, S. 2019

[雑誌論文] Pig saliva as a Streptococcus suis reservoir and potential source of infection on farms: Implications from a novel quantitative PCR

S. Arai, H. Kim, T. Watanabe, M. Tohya, E. Suzuki, K. Ishida-Kuroki, F. Maruyama, K. Murase, I. Nakagawa, T. Sekizaki 2018

[雑誌論文] Draft Genome Sequence of a Shewanella halifaxensis Strain Isolated from the Intestine of Marine Red Seabream (Pagrus major): Coding Integrative Conjugative Element with Macrolide Resistance Genes

Y. Sugimoto, F. Maruyama, S. Suzuki 2018

[学会発表] 下水・畜産排水に由来する薬剤耐性遺伝子の水圏環境での動態

鈴木 聡 2018

[学会発表] 海洋環境での薬剤耐性遺伝子の残存

鈴木 聡 2018

[雑誌論文] Interplay of a non-conjugative integrative element and a conjugative plasmid in the spread of antibiotic resistance via suicidal plasmid transfer from an aquaculture Vibrio isolate.

Nonaka, L., Yamamoto, T., Maruyama, F., Hirose, U., Onishi, Y., Kobayashi, T., Suzuki, S., Nomura, N., Masuda, M. and Yano, H. 2018

[雑誌論文] High temperature accelerates growth of aerobic anoxygenic phototrophic bacteria in seawater.

Sato-Takabe, Y., Hamasaki, K. and Suzuki, S. 2018

[雑誌論文] Tetracycline resistance gene tet(M) of a marine bacterial strain is not accumulated in bivalves from seawater in clam tank experiment and mussel monitoring

Suzuki, S., Makihara, N. and Kadoya, A. 2018

[学会発表] Conjugative gene transfer between marine bacteria and E. coli under nutritious and oligotrophic conditions.

Suzuki, S 2018

[雑誌論文] 薬剤耐性遺伝子の巨大リザーバとしての水圏環境:遺伝子のシンクとリンク.

鈴木 聡 2018

[学会発表] Dissemination of antibiotic resistance genes in the aquatic environment.

Suzuki, S 2018

[学会発表] Possible mechanisms of dissemination of antibiotic resistance genes in aquatic environment.

Suzuki, S 2018

[学会発表] Aquatic environments as a reservoir of antibiotic resistance genes.

Suzuki, S. 2017

[学会発表] 薬剤耐性遺伝子の巨大リザーバとしての水圏環境:レジストームとダイナミクス

鈴木 聡 2017

[図書] Antibiotic Resistance Genes in Natural Environments and Long-Term Effect

Suzuki, S. 2017

[図書] Antibiotic Resistance in Aquatic Systems

Suzuki, S., Pruden, A., Virta, M., Zhang, T. 2017

[雑誌論文] The novel mef(C)-mph(G) macrolide resistance gene cluster is conveyed in the environment on various vectors

Sugimoto Y, Suzuki S, Nonaka L, Boonla C, Sukpanyatham N, Chou H-Y, Wu J-H 2017

[図書] Antibiotic Resistance Genes in Natural Environments and Long-Term Effect

Suzuki S 2017

[学会発表] Antibiotic resistance gene transfer between marine bacteria and E.coli in starved cells and oligotrophic condition

Kohyama, Y. and Suzuki, S. 2017

[雑誌論文] Methodological considerations and comparisons of measurement results for extracellular proteolytic enzyme activities in seawater.

Obayashi, Y., Bong, C.W. and Suzuki, S. 2017

[雑誌論文] Release and Constancy of an Antibiotic Resistance Gene in Seawater under Grazing Stress by Ciliates and Heterotrophic Nanoflagellates

Bien, T.L.T.,Thao, N.V., Kitamura, S-I., Obayashi, Y. and Suzuki, S. 2017

[雑誌論文] 特集 薬剤耐性(AMR)対策 水環境に拡散する抗菌薬,薬剤耐性遺伝子の汚染実態と課題

鈴木 聡, 高田秀重 2017

[学会発表] 人獣医療と水圏環境間での薬剤耐性遺伝子の動態

鈴木 聡 2017

[図書] Antibiotic Resistance in Aquatic Systems

Suzuki S, Pruden A, Virta M, Zhang T 2017

[図書] Food Borne Diseases, 3rd Edition

Wondwossen A. G., Thomas W., Gregory H., Walid A., Usui, M. and Suzuki, S. 2017

[学会発表] 人獣医療と水圏環境間での薬剤耐性遺伝子の動態

鈴木 聡 2017

[学会発表] 多剤耐性遺伝子の環境中残存機構と人への暴露リスク評価

鈴木 聡 2017

[学会発表] Are humans accelerating the development of antibiotic resistance in the environment?: Aquaculture environment.

Suzuki S 2016

[学会発表] Formation and stability of extracellular antibiotic resistance plasmid pool in seawater under existence of ciliate and heterotrophic nanoflagella

Thanh BTL, Thao NV, Kitamura S-I, Obayashi Y, Suzuki S 2016

[雑誌論文] Use of Aeromonas spp. as general indicators of antimicrobial susceptibility among bacteria in aquatic environments in Thailand.

Usui M, Tagaki C., Fukuda A, Okubo T, Boonla C, Suzuki S, Seki K, Takada H, Tamura Y. 2016

[学会発表] 飢餓状態の菌および貧栄養環境での遺伝子水平伝達

香山義明、鈴木 聡 2016

[学会発表] 海洋細菌ゲノム上でマクロライド耐性遺伝子mef(C)-mph(G)を担うICEの解析

杉本 侑大、丸山 史人、鈴木 聡 2016

[雑誌論文] Abundance of common aerobic anoxygenic phototrophic bacteria in a coastal aquaculture area

Takabe Y-S, Nakao H, Kataoka T, Yokokawa T, Hamasaki K, Ohta K, Suzuki S 2016