トップ›研究者を探す›極限状態下微小生物の遺伝的変異と適応進化の階層モデルおよび解析手法の開発

極限状態下微小生物の遺伝的変異と適応進化の階層モデルおよび解析手法の開発

KAKEN 科学研究費助成事業データベース で見る
研究課題番号 KAKENHI-PROJECT-16300086
研究種目 基盤研究(B)
研究分野 総合・新領域系
総合領域
情報学
統計科学
研究機関 東京大学
代表研究者 岸野 洋久
研究分担者 徐 泰健
研究分担者 北添 康弘
研究分担者 渡部 輝明
研究期間 開始年月日 2004/4/1
研究期間 終了年度 2006
研究ステータス 完了 (2006/4/1)
配分額（合計） 13,600,000 (直接経費 :13,600,000)
配分額（履歴） 2006年度：3,800,000 (直接経費 :3,800,000)
2005年度：5,500,000 (直接経費 :5,500,000)
2004年度：4,300,000 (直接経費 :4,300,000)
キーワード ウイルス分子進化
宿主適応
配列進化と構造進化
集団構造と履歴
ゲノムの組換え
階層ベイズ
収斂進化
quasispecies
viral evolution
adaptation to the host
sequence and structure
population structure and history
recombination
Bayesian hierarchical model
convergent evolution

研究成果

[雑誌論文] Robust time estimation reconciles views of the antiquity of placental mammals.

Kitazoe.Y., Kishino.H., Waddell, P.J., Nakajima, N., Okabayashi, T., Watabe, T., Okuhara, Y. 2007

[雑誌論文] A likelihood-based index of protein-protein binding affinities with application to influenza HA escape from antibodies.

Watabe, T., Kishino, H., Martins, L.0., Kitazoe, Y. 2007

[雑誌論文] A likelihood-based index of protein-protein binding affinities with application to influenza HA escape from antibodies.

Watabe.T., Kishino, H., Martins, L.O., Kitazoe.Y. 2007

[雑誌論文] Core set approach to reduce uncertainty of gene trees

Okabayashi, T., Kitazoe, Y., Kishino, H., Watabe, T., Nakajima, N., Okuhara, Y., O'Loughlin, S., Walton, C. 2006

[雑誌論文] Core set approach to reduce uncertainty of gene trees.

Okabayashi, T., Kitazoe, Y., Kishino, H., Watabe.T., Nakajima, N., Okuhara, Y., O'Loughlin, S., Walton, C. 2006

[雑誌論文] Fold recognition of the HIV-1 V3 loop and flexibility of its crown structure during the course of adaptation to a host.

Watabe, T., Kishino, H., Okuhara, Y., Kitazoe, Y. 2006

[雑誌論文] Core set approach to reduce uncertainty of gene trees.

Okabayashi, T., Kitazoe, Y., Kishino, H., Watabe, T., Nakajima, N., Okuhara, Y., O'Loughlin, S., Walton,C. 2006

[雑誌論文] Fold recognition of the HIV-1 V3 loop and flexibility of its crown structure during the course of adaptation to a host.

Watabe.T., Kishino.H., Okuhara.Y., Kitazoe.Y. 2006

[雑誌論文] Fold recognition of the HIV-1 V3 loop and flexibility of its crown structure during the course of adaptation to a host.

Watabe, T., Kishino, H., Okuhara, Y., Kitazoe, Y. 2006

[雑誌論文] Multidimensional vector space representation for correlated evolution and molecular phylogeny.

Kitazoe, Y., Kishino, H., Okabayashi, T., Watabe, T., Nakajima, N., Okuhara, Y., Kurihara, Y. 2005

[雑誌論文] Multidimensional vector space representation for correlated evolution and molecular phylogeny

Kitazoe Y, H Kishino, T Okabayashi, T Watabe, N Nakajima, Y Okuhara 2005

[雑誌論文] Multidimensional vector space representation for correlated evolution and molecular phylogeny.

Kitazoe, Y., Kishino.H., Okabayashi, T., Watabe, T., Nakajima, N., Okuhara, Y., Kurihara, Y. 2005

[雑誌論文] Robust time estimation reconciles views of the antiquity of placental mammals.

Kitazoe, Y., Kishino, H., Waddell, P.J., Nakajima, N., Okabayashi, T., Watabe, T., Okuhara, Y.