トップ研究者を探すマラリア原虫スポロゾイトの肝臓細胞への感染機構

マラリア原虫スポロゾイトの肝臓細胞への感染機構

KAKEN 科学研究費助成事業データベース で見る
研究課題番号 KAKENHI-PROJECT-16017243
研究種目 特定領域研究
研究分野
研究機関 三重大学
代表研究者 鎮西 康雄
研究分担者 油田 正夫
研究分担者 石野 智子
研究期間 開始年月日 2004/4/1
研究期間 終了年度 2005
研究ステータス 完了 (2005/4/1)
配分額(合計) 15,000,000 (直接経費 :15,000,000)
配分額(履歴) 2005年度:7,500,000 (直接経費 :7,500,000)
2004年度:7,500,000 (直接経費 :7,500,000)
キーワード マラリア原虫
スポロゾイト
肝臓感染
ネズミマラリア
EST解析
遺伝子ノックアウト
感染機構
SPECT
ハマダラカ
クッパー細胞
malarial parasite
ookinete
sporozoite
infection mechanism
rodent malaria
Anpheline mosquito
Kupffer cell
liver infection

研究成果

[雑誌論文] A calcium-dependent protein kinase regulates PlasmodiumooKinete access to the midgut epithelial cell.

Tomoko Ishino, Yuki Orito, Yasuo Chinzei, Masao Yuda 2006

[雑誌論文] Two proteins with 6-cys motifs are required for malarial parasites to commit to infection of the hepatocyte.

Tomoko Ishino, Yasuo Chinzei, Masao Yuda 2006

[雑誌論文] A calcium-dependent protein kinase regulates Plasmodium ookinete access to the midgut epithelial cell.

Tomoko Ishino, Yuki Orito, Yasuo Chinzei, Masao Yuda. 2006

[雑誌論文] Two proteins with 6-cys motifs are required for malarial parasites to commit to infection of the hepatocyte.

Tomoko Ishino, Yasuo Chinzei, Masao Yuda 2006

[雑誌論文] A calcium-dependent protein kinase regulates Plasmodium ookinete access to the midgut epithelial cell.

Tomoko Ishino, Yuki Orito, Yasuo Chinzei, Masao Yuda 2006

[雑誌論文] (* : equally contributed) CelTOS, a novel malarial protein that mediates transmission to mosquito and vertebrate hosts.

Tohru Kariu*, Tomoko Ishino*, Kazuhisa Yano, Yasuo Chinzei, Masao Yuda. 2006

[雑誌論文] CelTOS, a novel malarial protein that mediates transmission to mosquito and vertebrate hosts.

Tohru Kariu^*, Tomoko Ishino^*, Kazuhisa Yano, Yasuo Chinzei, Masao Yuda. (*: equally contributed) 2006

[雑誌論文] CelTOS, a novel malarial protein that mediates transmission to mosquito and vertebrate hosts.

Tohru Kariu^*, Tomoko Ishino^*, Kazuhisa Yano, Yasuo Chinzei, Masao Yuda. (*:equally contributed) 2006

[雑誌論文] Plasmodium sporozoite micronemal protein with a membrane attack complex-related domain is required for breaching the liver sinusoidal cell layer prior to hepatocyte infection.

Tomoko Ishino, Yasuo Chinzei, Masao YudaA 2005

[雑誌論文] Two proteins with 6-cys motifs are required for malarial parasites to commit to infection of the hepatocyte.Mol.

Tomoko Ishino, Yasuo Chinzei, Masao Yuda 2005

[雑誌論文] A Plasmodium sporozoite protein with a membrane attack complex domain is required for breaching the liver sinusoidal cell layer prior to hepatocyte infection

Tomoko Ishino, Yasuo Chinzei, Masao Yuda 2005

[雑誌論文] Essential role of membrane-attack protein in malarial transmission to mosquito host

Kimie Kadota, Tomoko Ishino, Takahiro Matsuyama, Yasuo Chinzei, Masao Yuda 2004

[雑誌論文] Essential Role of membrane-attack protein in malarial transmission to mosquito host.

Kimie Kadota, Tomoko Ishino, Takahiro Matsuyama, Yasuo Chinzei, Masao Yuda 2004