トップ研究者を探す誘導γδT細胞を用いたがん化学療法腸管免疫療法の開発

誘導γδT細胞を用いたがん化学療法腸管免疫療法の開発

KAKEN 科学研究費助成事業データベース で見る
研究課題番号 KAKENHI-PROJECT-15K09570
研究種目 基盤研究(C)
研究分野 生物系
医歯薬学
内科系臨床医学
感染症内科学
研究機関 香川大学
代表研究者 今滝 修
研究分担者 植村 麻希子
研究期間 開始年月日 2015/4/1
研究期間 終了年度 2019
研究ステータス 完了 (2019/4/1)
配分額(合計) 4,810,000 (直接経費 :3,700,000、間接経費 :1,110,000)
配分額(履歴) 2018年度:260,000 (直接経費 :200,000、間接経費 :60,000)
2017年度:1,300,000 (直接経費 :1,000,000、間接経費 :300,000)
2016年度:1,560,000 (直接経費 :1,200,000、間接経費 :360,000)
2015年度:1,690,000 (直接経費 :1,300,000、間接経費 :390,000)
キーワード adaptive cell therapy
γδT細胞
細胞免疫療法
がん化学療法
自然免疫
腫瘍免疫
感染症
免疫不全
日和見感染症
獲得免疫

研究成果

[雑誌論文] Lethal cardiac damage resulting from eosinophilia caused by anaplastic large cell lymphoma

Imataki Osamu、Uemura Makiko、Kadowaki Norimitsu 2019

[雑誌論文] c-D-index is a risk factor for prolonged febrile neutropenia during chemotherapy in patients with acute myeloid leukemia.

Kubo Hiroyuki, Imataki Osama, Kubo Yukiko, Uemura M, Kadowaki N. 2019

[雑誌論文] Diagnostic Value of Flow Cytometry Standardized Using the European LeukemiaNet for Myelodysplastic Syndrome

Takeuchi Akihiro、Imataki Osamu、Kubo Hiroyuki、Kondo Akihiro、Seo Kayoko、Uemura Makiko、Yamaoka Genji、Murao Koji、Takeuchi Akihiro 2019

[雑誌論文] Asymptomatic hepatosplenomegaly in chronic myeloid leukemia.

Imataki Osamu、Uemura Makiko 2018

[雑誌論文] Pure erythroid leukemia in a polymyositis patient treated with azathioprine

Imataki Osamu、Takeuchi Akihiro、Uchida Shumpei、Yokokura Shigeyuki、Uemura Makiko、Kadowaki Norimitsu 2018

[雑誌論文] B-chronic lymphocytic leukemia showed triple transformation, to diffuse large B cell, CD20-negative, and T-cell neoplasm during ofatumumab treatment: a case report

Imataki Osamu、Uemura Makiko 2018

[雑誌論文] Voriconazole concentration is inversely correlated with corticosteroid usage in immunocompromised patients

Imataki Osamu、Yamaguchi Kazunori、Uemura Makiko、Fukuoka Noriyasu 2018

[雑誌論文] Central Nervous System Peripheral T Cell Lymphoma Manifesting as Lymphomatosis Cerebri That Was Misdiagnosed as Neuro-Beh?et’s Disease: A Case Report

Imataki Osamu、Uchida Shumpei、Yokokura Shigeyuki、Uemura Makiko、Kadowaki Norimitsu 2018

[雑誌論文] Lemongrass essential oil and citral inhibit Src/Stat3 activity and suppress the proliferation/survival of small-cell lung cancer cells, alone or in combination with chemotherapeutic agents

Maruoka Takayuki、Kitanaka Akira、Kubota Yoshitsugu、Yamaoka Genji、Kameda Tomohiro、Imataki Osamu、Dobashi Hiroaki、Bandoh Shuji、Kadowaki Norimitsu、Tanaka Terukazu 2018

[雑誌論文] Bendamustine and G-CSF support

Imataki Osamu、Uchida Shumpei、Yokokura Shigeyuki、Uemura Makiko、Kadowaki Norimitsu 2018

[雑誌論文] Strain-specific transmission in an outbreak of ESBL-producing Enterobacteriaceae in the hemato-oncology care unit: a cohort study.

Uemura M, Imataki O, Uchida S, Nakayama-Imaohji H, Ohue Y, Matsuka H, Mori H, Dobashi H, Kuwahara T, Kadowaki N. 2017

[雑誌論文] Nutritional risk in allogeneic stem cell transplantation: rationale for a tailored nutritional pathway.

Aoyama T, Imataki O, Mori K, Yoshitsugu K, Fukaya M, Okamura I, Enami T, Tatara R, Ikeda T. 2017

[雑誌論文] Methionine PET Might Be Reliable for the Detection of Low M-Protein-Producing Myelomas.

Imataki O, Uchida S, Yokokura S, Uemura M, Kadowaki N. 2017

[雑誌論文] Fatal Rhabdomyolysis Caused by <i>Morganella morganii</i> in a Patient with Multiple Myeloma

Imataki O, Uemura M. 2017

[雑誌論文] Low-dose anti-thymocyte globulin reduce severe acute and chronic graft-versus-host disease after allogeneic stem cell transplantation.

Imataki O, Matsumoto K, Uemura M. 2017

[雑誌論文] Anemia and hypogammaglobulinemia caused by M&eacute;n&eacute;trier's disease.

Imataki O, Uchida S, Yokokura S, Uemura M, Kadowaki N. 2017

[雑誌論文] Bladder Rupture After Chronic Hemorrhagic Cystitis in a Stem Cell Transplantation Recipient.

Imataki O, Uchida S, Kushida Y, Uemura M. 2017

[雑誌論文] Enteral Malakoplakia Prior to Helicobacter cinaedi Bacteremia.

Imataki O, Kawashima K, Uchida S, Yokokura S, Uemura M, Kadowaki N. 2017

[雑誌論文] Acquired Inhibitors to Multiple Coagulation Factors (V, IX, and XII) Identified in a Unique Patient with Hepatocellular Carcinoma

Imataki O, Arai T, Uemura M. 2017

[雑誌論文] Clinical impact of sarcopenia and relevance of nutritional intake in patients before and after allogeneic hematopoietic stem cell transplantation.

Tanaka S, Imataki O, Kitaoka A, Fujioka S, Hanabusa E, Ohbayashi Y, Uemura M, Arima N, Yamamoto T. 2017

[雑誌論文] Complete mimicry: a case of alveolar rhabdomyosarcoma masquerading as acute leukemia.

Imataki O, Uemura M, Uchida S, Yokokura S, Takeuchi A, Ishikawa R, Kondo A, Seo K, Kadowaki N. 2017

[雑誌論文] The Leading Seafood Cuisine of Anisakidosis in Japan.

Imataki O, Bandoh S, Kawakami K, Uemura M. 2016

[雑誌論文] Bone Marrow and Peripheral Blood: Which Is Safe?

Imataki O, Uchida S, Yokokura S, Uemura M, Matsushita K, Kadowaki N. 2016

[雑誌論文] Neurotropic infiltration and neuropathy of multifocal lymphoma.

Imataki O, Kida J, Yokohira M, Uemura M. 2016

[雑誌論文] Paradoxical thrombosis in idiopathic thrombocytopenic purpura.

Imataki O, Uchida S, Yokokura S, Uemura M, Kadowaki N. 2016

[雑誌論文] Perforation in an intestinal malignant lymphoma case.

Imataki O, Shiroshita K, Uchida S, Kida J, Akamoto S, Uemura M. 2016

[雑誌論文] Chromosomal abnormality of acute promyelocytic leukemia other than PML-RARA: a case report of acute promyelocytic leukemia with del(5q).

Imataki O, Uemura M. 2016

[雑誌論文] Fatal acute respiratory distress syndrome after stem cell infusion.

Imataki O, Ura K, Uemura M. 2016

[雑誌論文] Charlson comorbidity index predicts poor outcome in CML patients treated with tyrosine kinase inhibitor.

Uemura M, Imataki O, Kawachi Y, Kawakami K, Hoshijima Y, Matsuoka A, Kadowaki N. 2016

[雑誌論文] Chryseobacterium indologenes, a possible emergent organism resistant to carbapenem antimicrobials after stem cell transplantation.

Imataki O, Uemura M. 2016

[雑誌論文] CDR3β sequence motifs regulate autoreactivity of human invariant NKT cell receptors.

Chamoto K, Guo T, Imataki O, Tanaka M, Nakatsugawa M, Ochi T, Yamashita Y, Saito AM, Saito TI, Butler MO, Hirano N. 2016

[雑誌論文] Antilymphocyte Globulin for Chronic Graft-versus-Host Disease.

Imataki O, Uemura M, Kadowaki N. 2016

[雑誌論文] Tanaka S, Imataki O, Kitaoka A, Fujioka S, Hanabusa E, Ohbayashi Y, Uemura M, Arima N, Yamamoto T.

Clinical impact of sarcopenia and relevance of nutritional intake in patients before and after allogeneic hematopoietic stem cell transplantation. 2016

[雑誌論文] Ganciclovir-resistant HHV-6 encephalitis that progressed rapidly after bone marrow transplantation.

Imataki O, Uemura M. 2015

[雑誌論文] Persistent Left Superior Vena Cava in Hematological Malignancy Requiring Central Venous Catheter Insertion for Intensive Chemotherapy.

Imataki O, Kubo H, Hamasaki Y, Oku M, Kida J, Uemura M, Matsuka H. 2015

[雑誌論文] Anti-CD30 antibody-induced radiation recall reaction: a collateral target for activated lymphocytes.

Imataki O, Kubo H, Hamasaki Y, Oku M, Kida J, Uemura M. 2015

[雑誌論文] Marked Hematopoiesis Masquerading Multiple Bone Metastasis in a Lung Cancer Patient With Myelodysplastic Syndrome.

Imataki O, Uchida S, Shiroshita K, Kida J, Uemura M. 2015