研究成果

[学会発表] Development of T-Cell Therapy By Exploiting Modified Antibodies Specific for A2/NY-ESO-1 for Refractory Myeloma

Masaki Maruta, Toshiki Ochi, Kazushi Tanimoto, Taichi Azuma, Hiroshi Fujiwara, and Masaki Yasukawa 2017

[雑誌論文] Human tolerogenic dendritic cells generated with protein kinase C inhibitor are optimal for functional regulatory T cell induction

Adnan E, Yasukawa M, et al. 2016

[雑誌論文] The transcriptional repressor Gfi1 plays a critical role in the development of NKT1- and NKT2-type iNKT cells

Yasuoka, T. Yasukawa M, et al. 2016

[雑誌論文] Menin plays a critical role in the regulation of the antigen-specific CD8+ T cell response upon Listeria infection

Yamada T, Yasukawa M, et al. 2016

[学会発表] Phase 1 Clinical Trial of Adoptive Immunotherapy for Acute Myelogenous Leukemia and Myelodysplastic Syndrome, Using Gene-Modified Autologous Lymphocytes Expressing WT1-Specific T-Cell Receptor

Kazushi Tanimoto, Hiroshi Fujiwara, Isao Tawara, Masahiro Masuya, Shinichi Kageyama, Tetsuya Nishida, Makoto Murata, Seitaro Terakura, Yoshiki Akatsuka, Hiroaki Ikeda, Yoshihiro Miyahara, Ikuei Nukaya, Kazutoh Takesako, Nobuhiko Emi, Naoyuki Katayama, Hiroshi Shiku, Masaki Yasukawa 2016

[雑誌論文] Development of engineered T cells expressing a chimeric CD16-CD3ζ receptor to improve the clinical efficacy of mogamulizumab therapy against adult T cell leukemia

Tanaka H, Yasukawa M, et al. 2016

[雑誌論文] A functionally superior second-generation vector expressing an Aurora Kinase-A-specific T-cell receptor for anti-leukaemia adoptive immunotherapy

Casey, N.P., Yasukawa M, et al. 2016

[雑誌論文] Development of engineered T cells expressing a chimeric CD16-CD3ζ receptor to improve the clinical efficacy of mogamulizumab therapy against adult T cell leukemia

Tanaka H, Fujiwara H, Ochi F, Tanimoto K, Casey N, Okamoto S, Mineno J, Kuzushima K, Shiku H, Sugiyama T, Barrett J, Yasukawa M. 2016

[学会発表] Immunotherapy with Chimeric Antigen Receptor Targeting Intracellular WT1 Gene Product Complexed with HLA-a*24:02 Molecule

Hiroaki Ikeda, Yasushi Akahori, Motohiro Yoneyama, Yuki Orito, Yoshihiro Miyahara, Yasunori Amaishi, Sachiko Okamoto, Junichi Mineno, Kazutoh Takesako, Hiroshi Fujiwara, Masaki Yasukawa, Hiroshi Shiku 2015

[学会発表] Targeting Aurora Kinase with a Superior T-Cell Receptor Gene-Transfer Vector

Nicholas Casey, Hiroshi Fujiwara, Kazushi Tanimoto, Sachiko Okamoto, Junichi Mineno, Kiyotaka Kuzushima, Hiroshi Shiku, Masaki Yasukawa 2015

[学会発表] Adoptive Transfer of WT1-Specific TCR Gene-Transduced Lymphocytes in Patients with Myelodysplastic Syndrome and Acute Myeloid Leukemia

Isao Tawara, Masahiro Masuya, Shinichi Kageyama, Tetsuya Nishida, Seitaro Terakura, Makoto Murata, Hiroshi Fujiwara, Yoshiki Akatsuka, Hiroaki Ikeda, Yoshihiro Miyahara, Daisuke Tomura, Ikuei Nukaya, Kazutoh Takesako, Nobuhiko Emi, Masaki Yasukawa, Naoyuki Katayama, Hiroshi Shiku 2015