研究成果

[学会発表] Ovarian metastasectomy in colorectal cancer may improve the clinical outcomes of patients with metastatic colorectal cancer regardless of BRAF or KRAS mutational profiles

Yoshiko Mori, Takeshi Nagasaka, Hiroaki Tanioka, Akihiro Nyuya, Takashi Kawai, Toshiaki Toshima, Kazuya Yasui, Kunitoshi Shigeyasu, Hiroyuki Kishimoto, Yuzo Umeda, Toshiyoshi Fujiwara 2017

[学会発表] 切除不能進行再発大腸がんの２次治療以降における Ramcirumab + FOLFIRI 療法の治療成績

永坂岳司, 母里淑子, 重安邦俊, 河合　毅, 矢野修也, 岸本浩行, 楳田祐三, 山口佳之, 藤原俊義 2017

[学会発表] Gene expression signatures in BRAF V600E mutant colorectal cancer in relation to WNT signaling cascade

asui K, Nagasaka T, Nyuya A, Toshima T, Kawai T, Shigeyasu K, Yano S, Mori Y, Haraga J, Nakamura K, Umeda Y, Goel A, Fujiwara T 2017

[学会発表] StageIV大腸癌に対するPrecision Medicineの構築

河合　毅, 永坂岳司, 母里淑子, 楳田祐三, 稲田　涼, 谷口文崇, 安井和也, 戸嶋俊明, 岸本浩行, 藤原俊義 2017

[学会発表] utcome of locally advanced rectal cancer with or without preoperative treatments

母里淑子, 永坂岳司, 稲田　涼, 河合　毅, 近藤喜太, 浅野博昭, 佃　和憲, 木村圭佑, 楳田祐三, 岸本浩行, 藤原俊義 2017

[学会発表] Heterogenity of epigenetic and EMT marks observed in hepatocellular carcinoma with keratin 19 proficiency

Nagasaka T, Okada T, Yokomichi N, Taniguchi F, Toshima T, Yasui K, Fuji T, Mori Y, Kawai T, Umeda Y, Yagi T, Fujiwara T, Goel A 2017

[学会発表] 遺伝子変異情報に基づいた大腸癌肝転移の治療戦略―原発巣の左右局在とRAS/RAF 変異の意義―

楳田祐三, 永坂岳司, 母里淑子, 吉田龍一, 信岡大輔, 杭瀬　崇, 藤　智和, 河合　毅, 荒木宏之, 八木孝仁, 藤原俊義 2017

[雑誌論文] Living Donor Liver Transplantation for Acute Liver Failure : Comparing Guidelines on the Prediction of Liver Transplantation

Yoshida K, Umeda Y, Takaki A, Nagasaka T, Yoshida R, Nobuoka D, Kuise T, Takagi K, Yasunaka T, Okada H, Yagi T, Fujiwara T. 2017

[学会発表] 大腸癌多発肝転移におけるRAS/RAF変異の意義～生物学的悪性度から術前化学療法適応を見極める～

楳田祐三, 八木孝仁, 永坂岳司, 吉田龍一, 信岡大輔, 母里淑子, 杭瀬　崇, 高木弘誠, 河合　毅, 藤原俊義 2017

[学会発表] Gene expression profiles in BRAF V600E mutant colorectal cancer and association with SFRP2 methylation status

Kazuya Yasui, Takeshi Nagasaka, Toshiaki Toshima, Takashi Kawai, Kunitoshi Shigeyasu, Yoshiko Mori, Junko Haraga, Keiichiro Nakamura, Yuzo Umeda, Hiroshi Tazawa, Ajay Goel, Toshiyoshi Fujiwara 2017

[学会発表] 局所進行直腸癌に対する術前化学療法の有用性

母里淑子, 永坂岳司, 河合　毅, 重安邦俊, 矢野修也, 近藤喜太, 楳田祐三, 岸本浩行, 藤原俊義 2017

[学会発表] A Novel Circulating Cell Free DNA-Based Assay Can Predict Tumor Response to Systematic Chemotherapy

T. Toshima, T. Nagasaka, Y. Mori, T. Kawai, K. Yasui, T. Fuji, F. Taniguchi, K. Kimura, H. Kishimoto, Y. Umeda, A. Goel, T. Fujiwara 2017

[学会発表] 便中メチル化CpG検出による非侵襲的大腸癌スクリーニング技術の実用化を目指して

永坂岳司, 母里淑子, 入谷光洋, 安井和也, 戸嶋俊明, 河合　毅, 重安邦俊, 谷口文崇, 藤　智和, 楳田祐三, 岸本浩行, 藤原俊義 2017

[学会発表] MGMT Inactivation Arrest Tumor Growth and Serves As a Promising Predictive Biomarker for Treatment Response in Colorectal Cancer

Mori Y, Nagasaka T, Tazawa H, Umeda Y, Shigeyasu K, Yoshida K, Goel A, Fujiwara T 2016

[学会発表] 膵癌切除症例における免疫チェックポイント分子の発現解析～膵癌切除例とTCGA dataを対象とした免疫チェックポイント機構の解析～

藤　智和, 楳田祐三, 永坂岳司, 母里淑子, 谷口文崇, 安井和也, 河合　毅, 八木孝仁, 藤原俊義 2016

[学会発表] A novel circulating cell free DNA-based assay in colorectal cancer patients during treatment with systematic chemotherapy

Toshima T, Nagasaka T, Mori Y, Kawai T, Fuji T, Taniguchi F, Kimura K, Yasui K, Kishimoto H, Umeda Y, Tazawa H, Goel A, Fujiwara T 2016

[学会発表] PD-1 and PD-L1 expression patterns and DNA mismatch repair status for precision management of patients with gastric cancer

Kimura K, Nagasaka T, Mori Y, Kawai T, Fuji T, Taniguchi F, Yasui K, Toshima T, Umeda Y, Tazawa H, Goel A, Fujiwara T 2016

[学会発表] Micro RNAs as promising therapeutic targets for anti-metastatic therapy in colorectal cancer

Kawai T, Nagasaka T, Mori Y, Fuji T, Taniguchi F, Kimura K, Toshima T, Yasui K, Umeda Y, Tazawa H, Goel A, Fujiwara T 2016

[学会発表] Comprehensive analysis of intrahepatic cholangiocarcinoma based on viral infections and mutational status in the IDH1/2 and KRAS genes

Yasui K, Nagasaka T, Umeda Y, Fuji T, Taniguchi F, Toshima T, Kimura K, Kawai T, Mori Y, Tazawa H, Yagi T, Goel A, Fujiwara T 2016

[学会発表] Lynch症候群および家族性大腸腺腫症の系統的遺伝子解析

谷口文崇, 永坂岳司, 楳田祐三, 母里淑子, 河合 毅, 内海方嗣, 田中屋宏爾, 青木秀樹, 竹内仁司, 藤原俊義 2016

[学会発表] Acquired Resistance to Anti-Epidermal Growth Factor Receptor Therapy in Metastatic Colorectal Cancer

谷口文崇, 永坂岳司, 藤　智和, 母里淑子, 岸本浩行, 河合　毅, 楳田祐三, 藤原俊義 2016

[雑誌論文] The rare BRAF VK600-601E mutation as a possible indicator of poor prognosis in rectal carcinoma - a report of a case.

Mori Y, Nagasaka T, Mishima H, Umeda Y, Inada R, Kishimoto H, Goel A, Fujiwara T. 2015

[学会発表] Non invasive detection of methylated CpGs from sputum can predict patiets with lung cancer

Kawai T, Nagasaka T, Takehara Y, Umeda Y, Fuji T, Taniguchi F, Kimura K, Toshima T, Yasui K, Mori Y, Kishimoto H, Toyooka S, Goel A, Fujiwara T 2015