トップ研究者を探すDNAアフィニティー精製法を用いた新規BMPシグナル伝達分子の探索と機能解析

DNAアフィニティー精製法を用いた新規BMPシグナル伝達分子の探索と機能解析

KAKEN 科学研究費助成事業データベース で見る
研究課題番号 KAKENHI-PROJECT-15591611
研究種目 基盤研究(C)
研究分野 生物系
医歯薬学
外科系臨床医学
整形外科学
研究機関 (財)癌研究会
代表研究者 今村 健志
研究期間 開始年月日 2003/4/1
研究期間 終了年度 2004
研究ステータス 完了 (2004/4/1)
配分額(合計) 3,500,000 (直接経費 :3,500,000)
配分額(履歴) 2004年度:1,700,000 (直接経費 :1,700,000)
2003年度:1,800,000 (直接経費 :1,800,000)
キーワード BMP
Smad
Gcn5
蛋白質-DNA相互作用
シグナル伝達
BMP
Smad
Gcn5

研究成果

[雑誌論文] Roles for the MH2 domain of Smad7 in the specific inhibition of transforming growth factor-β superfamily signaling.

Mochizuki T, Miyazaki H, Hara T, Furuya T, Imamura T, Watabe T, Miyazono K 2004

[雑誌論文] Roles for the MH2 domain of Smad7 in the specific inhibition of transforming growth factor-β superfamily signaling

Mochizuki T, Imamura T (他5名) 2004

[雑誌論文] Regulation of transforming growth factor-β and bone morphogenetic protein signaling by transcriptional co-activator GCN5.

Kahata K, Imamura T (外7名) 2004

[雑誌論文] Roles for the MH2 domain of Smad7 in the specific inhibition of transforming growth factor-β superfamily signaling.

Mochizuki T, Imamura T (他5名) 2004

[雑誌論文] Regulation of transforming growth factor-β and bone morphogenetic protein signaling by transcriptional co-activator GCN5.

Kahata K, Hayashi M, Asaka M, Hellman U, Kitagawa H, Yanagisawa J, Kato S, Imamura T, Miyazono M 2004

[雑誌論文] Coordinate regulation of cell growth and differentiation by TGF-β superfamily and Runx proteins.

Miyazono K, Meda S, Imamura T 2004

[雑誌論文] Coordinate regulation of cell growth and differentiation by TGF-β superfamily and Runx proteins.

Miyazono K, Meda S, Imamura T 2004

[雑誌論文] Coordinate regulation of cell growth and differentiation by TGF-β superfamily and Runx proteins.

Miyazono K, Meda S, Imamura T 2004

[雑誌論文] SB-431542 and Gleevec inhibit TGF-β induced growth stimulation of human osteosarcoma cells.

Matsuyama S, Kondo M, Saitoh M, Shimizu K, Aburatani H, Mishima K, Imamura T, Miyazono K, Miyazawa K 2003

[雑誌論文] Regulation of TGF-β signaling and its roles in progression of tumors.

Miyazono K, Suzuki H, Imamura T 2003

[雑誌論文] SB-431542 and Gleevec inhibit TGF-β induced growth stimulation of human osteosarcoma cells.

Matsuyama S, Imamura T (外9名) 2003

[雑誌論文] Regulation of TGF-β signaling and its roles in progression of tumors.

Miyazono K, Suzuki H, Imamura T 2003