トップ研究者を探す正常肝、慢性肝炎、肝硬変、肝細胞癌におけるプロテオーム解析-新しい診断、治療、発生予防の開発を目指して-

正常肝、慢性肝炎、肝硬変、肝細胞癌におけるプロテオーム解析-新しい診断、治療、発生予防の開発を目指して-

KAKEN 科学研究費助成事業データベース で見る
研究課題番号 KAKENHI-PROJECT-15590654
研究種目 基盤研究(C)
研究分野 生物系
医歯薬学
内科系臨床医学
消化器内科学
研究機関 香川大学
香川大学(医学部)
代表研究者 正木 勉
研究分担者 栗山 茂樹
研究分担者 渡邊 精四郎
研究分担者 黒河内 和貴
研究期間 開始年月日 2003/4/1
研究期間 終了年度 2004
研究ステータス 完了 (2004/4/1)
配分額(合計) 3,500,000 (直接経費 :3,500,000)
配分額(履歴) 2004年度:700,000 (直接経費 :700,000)
2003年度:2,800,000 (直接経費 :2,800,000)
キーワード 細胞周期
肝癌
p18^<INK4C>
サイクリン
Shc
LECラット
hepatocllular carcinoma
cell cycle
Cdk
Cdk inhibitor
p18^<INK4C>

研究成果

[雑誌論文] Enhanced expression of adaptor molecule p46 Shc in nuclei of gastric cancer.

Yukimasa S, Masaki T, Funaki T, 13 others. 2005

[雑誌論文] Enhanced expression of adaptor molecule p46 Shc in nuclei of gastric cancer.

Yukimasa S, Masaki T, Funaki T, 13 others 2005

[雑誌論文] Expression of myristoylated alanine-rich C kinase substrate(MARCKS)in hepatocellular carcinoma : comparative study of hepatocellular carcinoma versus liver cirrhosis, chronic hepatitis and normal liver.

Masaki T, Tokuda M, Yoshida S, 16 others. 2005

[雑誌論文] Expression of myristoylated alanine-rich C kinase substrate (MARCKS) in hepatocellular carcinoma : comparative study of hepatocellular carcinoma versus liver cirrhosis, chronic hepatitis and normal liver.

Masaki T, Tokuda M, Yoshida S, 16 others 2005

[雑誌論文] Identification of p46Shc overexpressed in hepatoccellular nuclei with high proliferative activity : study of regenerating rat liver.

Yuji J, Masaki T, Yoshida S, 9 others. 2004

[雑誌論文] Enhanced expression of adaptor molecule p46Shc in nuclei of hepatocellular carcinoma : study of Lec rats.

Yoshida S, Masaki T, Feng H, 9 others. 2004

[雑誌論文] Reduced Expression of Cell Cycle Regulator p18^<INK4C> in Human Hepatocellular Carcinoma.

Morishita A, Masaki T, Yoshiji H, 14 others. 2004

[雑誌論文] Correlation of Skp2 with carcinogenesis, invasion, metastasis, and prognosis in colorectal tumors.

Li JQ, Wu F, Masaki T, 7 others 2004

[雑誌論文] Enhanced expression of adaptor molecule p46Shc in nuclei of hepatocellular carcinoma : study of Lec rats.

Yoshida S, Masaki T, Feng H, 9 others 2004

[雑誌論文] Reduced Expression of Cell Cycle Regulator p18^<INK4C> in Human Hepatocellular Carcinoma

Morishita A, Masaki T, Yoshiji H, 14 others 2004

[雑誌論文] Correlation of Skp2 with carcinogenesis, invasion, metastasis, and prognosis in colorectal tumors.

Li JQ, Wu F, Masaki T, 7 ohters 2004

[雑誌論文] Reduced Expression of Cell Cycle Regulator p184^<INK4C> in Human Hepatocellular Carcinoma.

Morishita A, Masaki T, Yoshiji H, 14 others 2004

[雑誌論文] Enhanced expression of adaptor molecule p46Shc in nuclei of hepatocellular carcinoma study of Lec rats

Yoshida S, Masaki T, Feng H, 9 others 2004

[雑誌論文] Identification of p46Shc overexpressed in hepatoccellular nuclei with high proliferative activity : study of regenerating rat liver.

Yuji J, Masaki T, Yoshida S, 9 others 2004

[雑誌論文] Correlation of Skp2 with carcinogenesis, invasion, metastasis, and prognosis in colorectal tumors.

Li JQ, Wu F, Masaki T, 7 others. 2004

[雑誌論文] Cyclins and cyclin-dependent kinases : comparative study of hepatocellular carcinoma versus cirrhosis.

Masaki T, Shiratori Y, Rengifo W, 9 others. 2003

[雑誌論文] pp60^<c-src> Activation in Lung Adenocarcinoma.

Masaki T, Igarashi K, Tokuda M, 11 others 2003

[雑誌論文] Cyclins and cyclin-dependent kinases : comparative study of hepatocellular carcinoma versus cirrhosis.

Masaki T, Shiratori Y, Rengifo W, 9 others 2003

[雑誌論文] Cyclins and cyclin-dependent kinases : comparative study of hepatocellular carcinoma versus cirrhosis

Masaki T, Shiratori Y, Rengifo W, 9 others 2003

[雑誌論文] pp60^<c-src> Activation in Lung Adenocarcinoma.

Masaki T, Igarashi K, Tokuda M, 11 others. 2003