トップ研究者を探す循環動態変化に伴う心血管系組織のmitoATP感受性Kチャネルと活性酸素産生関連

循環動態変化に伴う心血管系組織のmitoATP感受性Kチャネルと活性酸素産生関連

KAKEN 科学研究費助成事業データベース で見る
研究課題番号 KAKENHI-PROJECT-15590230
研究種目 基盤研究(C)
研究分野 生物系
医歯薬学
基礎医学
薬理学一般
研究機関 香川大学
香川大学(医学部)
代表研究者 木村 正司
研究分担者 安部 陽一
研究分担者 宮武 明
研究分担者 西山 成
研究期間 開始年月日 2003/4/1
研究期間 終了年度 2004
研究ステータス 完了 (2004/4/1)
配分額(合計) 3,700,000 (直接経費 :3,700,000)
配分額(履歴) 2004年度:900,000 (直接経費 :900,000)
2003年度:2,800,000 (直接経費 :2,800,000)
キーワード 高血圧
アンジオテンシン
活性酸素
心筋虚血再環流障害
ミトコンドリア
アドレナリン受容体
MAPキナーゼ
angiotensin
Hypertension
Superoxide
Ischemic-reperfudion injury
Mitochondria
Adrenergic receptor
Mitogen-activated protein kinase

研究成果

[雑誌論文] Mitochondria- derived reactive oxygen species and vascular MAP kinases : Comparison of angiotensin II and diazoxide.

Kimura S.et al. 2005

[雑誌論文] Roles of ROS derived from NAD(P)H oxidase and mitochondria in cardioprotection of ischemic reperfusion injury by angiotensin II.

Kimura Shoji 2005

[雑誌論文] Roles of NAD(P)H oxidase and mitochondria-derived reactive oxygen species in cardioprotection of ischemic reperfusion injury by angiotensin II.

Kimura Shoji 2005

[雑誌論文] Mitochondria-derived Reactive Oxygen Species and Vascular MAP Kinases : Comparison of Angiotensin II and Diazoxide.

Kimura Shoji 2005

[雑誌論文] Roles of NAD(P)H oxidase- and mitochondria-derived reactive oxygen species in cardioprotection of ischemic reperfusion injury by angiotensin II.

Kimura S.et al. 2005

[雑誌論文] Possible contribution of reactive oxygen species and mitogen-activated protein kinase to renal injury in aldosterone/salt-induced hypertensive rats.

Nishiyama A. et al. 2004

[雑誌論文] The SOD mimetic tempol ameliorates glomerular injury and reduces mitogen-activated protein kinase actibvity in Dahl salt-sensitive rats.

Nishiyama A. et al. 2004

[雑誌論文] Effects of ATI receptor blockade on renal injury and mitogen-activated protein kinase activity in Dahl salt-sensitive rats.

Nishiyama A.et al. 2004

[雑誌論文] The SOD mimetic tempol ameliorates glomerular injury and reduces mitogen-activated protein kinase activity in Dahl salt-sensitive rats.

Nishiyama A.et al. 2004

[雑誌論文] Effects of AT1 receptor blockade on renal injury and mitogen-activated protein activity in Dahl salt-sensitive rats.

Nishiyama A. et al. 2004

[雑誌論文] Possible contribution of reactive oxygen species and mitogen-activated protein kinase to renal injury in aldosterone/salt-induced hypertensive rats.

Nishiyama A.et al. 2004

[雑誌論文] Malfunction of vascular control in lifestyle-related diseases : Oxidative stress of angiorensin II -induced hypertension : Mitogen-activated protein kinases and blood pressure regulation.

Kimura S.et al. 2004

[雑誌論文] Time-dependent transition of tempol-sensitive reduction of blood pressure in angiotensin II-induced hypertension.

Kimura Shoji 2004

[雑誌論文] Time dependent transition of tempol sensitive reduction of blood pressure in angiotensin II induced hypertension.

Kimura S.et al. 2004

[雑誌論文] Malfunction of Vascular Control in Lifestyle-Related Diseases : Oxidative Stress of Angiotensin II-induced Hypertension : Mitogen-Activated Protein Kinases and Blood Pressure Regulation.

Kimura Shoji 2004

[雑誌論文] Role of angiotensin II and reactive oxygen species in cyclosporine A-dependent hypertension.

Nishiyama A.et al. 2003

[雑誌論文] Role of angiotensin II and reactive oxygen species in cyclosporine A-dependent hypertension.

Nishiyama A. 2003