トップ›研究者を探す›筋肉衰退の抑制効果を持つペプチドミミックの設計・合成と活性評価

筋肉衰退の抑制効果を持つペプチドミミックの設計・合成と活性評価

KAKEN 科学研究費助成事業データベース で見る
研究課題番号 KAKENHI-PROJECT-15510177
研究種目 基盤研究(C)
研究分野 総合・新領域系
複合新領域
生体分子科学
生物分子科学
研究機関 徳島大学
代表研究者 根本 尚夫
研究分担者 二川 健
研究分担者 渋谷 雅之
研究期間 開始年月日 2003/4/1
研究期間 終了年度 2004
研究ステータス 完了 (2004/4/1)
配分額（合計） 3,900,000 (直接経費 :3,900,000)
配分額（履歴） 2004年度：1,100,000 (直接経費 :1,100,000)
2003年度：2,800,000 (直接経費 :2,800,000)
キーワード Masked Acyl Cyanide
ペプチドミミック
筋肉衰退抑制
高齢者社会への対応
宇宙時代への対応
umpolung
ユビキチン
MAC反応剤
アシルアニオン等価体
Masked Acyl Cyanide
peptide mimics
ubiquitin
umpolung
correspondence of an aging society
correspondence of the space age
inhibition effect of reducing musclar strength

研究成果

[雑誌論文] Synthesis of a water-soluble molecular tweezer and a recognition study in an aqueous media

Nemoto, Hisao, Kawano, Tomoaki, Ueji, Nobuo, Sakamoto, Nobutaka, Araki, Takaaki, Miyoshi, Norikazu, Suzuki, Ichiro, Shibuya, Masayuki 2005

[雑誌論文] Synthesis of a water-soluble molecular tweezer and a recognition study in an aqueous media

Nemoto, Hisao 2005

[雑誌論文] Synthesis of a water-soluble molecular tweezer and a recognition study in an aqueous media

Nemoto, Hisao 2005

[雑誌論文] Highly efficient chiral resolution and determination of absolute configuration of 2-alkanols by using a cyclopenta[b]furan derivative

Nemoto, Hisao, Tsutsumi, Hiroe, Yuzawa, Satomi, Peng, Xian, Zhong, Weihui, Xie, Jun, Miyoshi, Norikazu, Suzuki, Ichiro, Shibuya, Masayuki 2004

[雑誌論文] Synthesis and DNA damaging ability of enediyne model compounds possessing photo-triggering devices

Suzuki, Ichiro, Uno, Shinsaku, Tsuchiya, Yuko, Shigenaga, Akira, Nemoto, Hisao Shibuya, Masayuki 2004

[雑誌論文] Developments of enediyne model compounds generating biradicals with an enhanced radical character-regulation of triggering devices

Suzuki, Ichiro, Shigenaga, Akira, Nemoto, Hisao, Shibuya, Masayuki 2004

[雑誌論文] Synthesis and DNA damaging ability of enediyne-polyamine conjugates

Suzuki, Ichiro, Shigenaga, Akira, Nemoto, Hisao, Shibuya, Masayuki 2004

[雑誌論文] Highly efficient chiral resolution and determination of absolute configuration of 2-alkanols by using a cyclopehta[b]furan derivative

Nemoto, Hisao 2004

[雑誌論文] MAC reagents : Three-components coupling reaction with one carbon homologation

Nemoto, Hisao 2004

[雑誌論文] Highly efficient chiral resolution and determination of absolute configuration of 2-alkanols by using a cyclopenta[b]furan derivative

Nemoto, Hisao 2004

[雑誌論文] Process for preparation and separation of 2-oxabicyclo[3.3.0]octane derivatives

Sakamoto, Kei, Nakano, Yasuyuki, Kondou, Yoshihisa, Yamada, Toshiro, Nemoto, Hisao 2004

[雑誌論文] MAC反応剤-簡便な1炭素増炭型3成分連結反応-

根本尚夫 2004

[雑誌論文] MAC反応剤-簡便な1炭素増炭型3成分連結反応-

根本尚夫 2004

[雑誌論文] Preparation of glycerol derivatives for modification of physiologically active polypeptides

Nemoto, Hisao, Yamasaki, Motoo, Suzawa, Toshiyuki, Yamaguchi, Hiroyuki 2004

[雑誌論文] Synthesis, reactions and DNA damaging abilities of 10-membered enediyne-sulfone and related compounds

Suzuki, Ichiro, Shigenaga, Akira, Manabe, Atsuo, Nemoto, Hisao, Shibuya, Masayuki 2003

[雑誌論文] Process for preparation of dicyanomethyl esters

Nemoto, Hisao 2003