トップ研究者を探す細胞増殖因子徐放性生体内吸収材料による胸腔内充填組織誘導の研究

細胞増殖因子徐放性生体内吸収材料による胸腔内充填組織誘導の研究

KAKEN 科学研究費助成事業データベース で見る
研究課題番号 KAKENHI-PROJECT-15390418
研究種目 基盤研究(B)
研究分野 生物系
医歯薬学
外科系臨床医学
胸部外科学
研究機関 香川大学
香川大学(医学部)
代表研究者 横見瀬 裕保
研究分担者 岡本 卓
研究分担者 山本 恭通
研究分担者 黄 政龍
研究分担者 田端 泰彦
研究期間 開始年月日 2003/4/1
研究期間 終了年度 2004
研究ステータス 完了 (2004/4/1)
配分額(合計) 9,900,000 (直接経費 :9,900,000)
配分額(履歴) 2004年度:4,900,000 (直接経費 :4,900,000)
2003年度:5,000,000 (直接経費 :5,000,000)
キーワード ゼラチンビーズ
肺全摘術後症候群
予防
肺葉切除後死腔
ポリ乳酸・カプロラクトン共重合体
bFGF
肉芽形成
胸膜肥厚
全摘後症候群
治療
ポリ乳酸
カプロラクトン
組織再生
FGF徐放化
gelatin micro-spheres
lactic acid and caprolactone copolymer cube
granulation
thoracic cavity
basic fibroblast growth factor
rabbits
pneumonectomy
inflammatory cells

研究成果

[雑誌論文] The regeneration of canine tracheal cartilage using the slow release of basic fibroblast growth factor (b-FGF) from a gelatin sponge.

Hitoshi Igai, Masashi Gotoh, Yasumichi Yamamoto, Hiroyasu Yokomise, Noriyuki Misaki, Taku Okamoto, Masaya Yamamoto, Yasuhiko Tabata 2005

[雑誌論文] Induction of granulation inside of the lactic acid and caprolactone copolymer cube in rabbit's post pneumonectomy thoracic cavity and the evaluation of the effect of slow releasing of basic fibroblast growth factor from a gelatin micro-sphere.

Noriyuki Misaki, Yasumichi Yamamoto, Taku Okamoto, Sung Soo Chang, Hitoshi Igai, Masashi Gotoh, Toshihiro Kushibiki, Yasuhiko Tabata, Hiroyasu Yokomise 2005

[雑誌論文] Bioabsorbable artificial trachea with slow release of bone morphogenetic protein (BMP)-2 : a comparative evaluation of two different suturing techniques.

Yasumichi Yamamoto, Sung Soo Chang, Hitoshi Igai, Noriyuki Misaki, Masashi Gotoh, Hiroyasu Yokomise, Taku Okamoto, Masaya Yamamoto, Yasuhiko Tabata 2005

[雑誌論文] Cartilage regeneration using slow release of bone morphogenetic protein (BMP)-2 from a gelatin sponge to treat experimental canine tracheomalacia : a preliminary report.

Taku Okamoto, Yasumichi Yamamoto, Masashi Gotoh, Dage Liu, Minoru Kihara, Kotaro Kameyama, Eiichi Hayashi, Kenji Nakamura, Akira Yamauchi, Cheng-long Huang, Hiroyasu Yokomise, Masaya Yamamoto, Tatsuo Nakamura, Yasuhiko Shimizu, Yasuhiko Tabata 2003

[雑誌論文] Experimental Study of Bone Morphogenetic Proteins-2 Slow Release From an Artificial Trachea Made of Biodegradable Materials : Evaluation of Stenting Time.

Yasumichi Yamamoto, Taku Okamoto, Masashi Gotoh, Hioyasu Yokomise et al. 2003

[雑誌論文] Experimental Study of Bone Morphogenetic Proteins-2 Slow Release From an Artificial Trachea Made of Biodegradable Materials : Evaluation of Stenting Time.

Yasumichi Yamamoto, Taku Okamoto, Masashi Gotoh, Hiroyasu Yokomise, Masaya Yamamoto, Yasuhiko Tabata 2003

[雑誌論文] Slow release of bone morphogenetic protein 2 from a gelatin sponge to promote regeneration of tracheal cartilage in a canine model

Taku Okamoto, Yasumichi Yamamoto, Masashi Gotoh, Cheng-Long Huang, Tatuo Nakamura, Yasuhiko Shimizu, Yasuhiko Tabata, Hiroyasu Yokomise 2003

[雑誌論文] Cartilage regeneration using slow release of bone morphogenetic protein (BMP)-2 from a gelatin sponge to treat experimenttal canine tracheomalacia : a prelininary report

Taku Okamoto, Yasumichi Yamamoto, Masashi Gotoh et al. 2003

[雑誌論文] Slow release of bone morphogenetic protein 2 from a gelatin sponge to promote regeneration of tracheal cartilage in a canine model.

Taku Okamoto, Yasumichi Yamamoto, Masashi Gotoh et al. 2003

[雑誌論文] Induction of granulation inside of the lactic acid and caprolactone copolymer cube in rabbit's post pneumonectomy thorac cavity and the evaluation of the effect of slow releasing of basic fibroblast growth factor from a gelatin micro-sphere.

Noriyuki Misaki, Yasumichi Yamamoto, Taku Okamoto et al.

[雑誌論文] Bioabsorbable artificial trachea with slow release of bone morphogenetic proenin (BMP)-2 : a comparative evaluation of two different suturine techniques.

Yasumichi Yamamoto, Sung Soo Chang, Hitoshi Igai et al.

[雑誌論文] The regeneration of canine tracheal cartilage using the slow release of basic fibroblast growth factor (b-FGF) from a gelatin sponge

Hitoshi Igai, Masashi Gotoh, Yasumichi Yamamoto et al.