周生期ストレスが子供の脳発達に及ぼす影響-母子間相互作用の発達精神病理学的解析

トップ›研究者を探す›周生期ストレスが子供の脳発達に及ぼす影響-母子間相互作用の発達精神病理学的解析

周生期ストレスが子供の脳発達に及ぼす影響-母子間相互作用の発達精神病理学的解析

代表研究者	三木崇範
研究課題番号	KAKENHI-PROJECT-14571050
研究種目	基盤研究(C)
研究分野	医学内科胎児・新生児医学
研究機関	香川大学香川大学(医学部)
研究分担者	横山俊史
研究分担者	日下隆
研究分担者	渡邊岳海
研究分担者	伊藤進
研究分担者	竹内義喜
研究分担者	松本由樹
研究分担者	宮武良輔
研究期間開始年月日	2002/4/1
研究期間終了年度	2004
研究ステータス	完了 (2004/4/1)
配分額（合計）	4,000,000 (直接経費 :4,000,000)
配分額（履歴）	2004年度：700,000 (直接経費 :700,000) 2003年度：1,100,000 (直接経費 :1,100,000) 2002年度：2,200,000 (直接経費 :2,200,000)
キーワード	母仔分離海馬神経細胞周生期ストレス曝露神経発達神経栄養因子 BDNF mRNA Real-time PCR 組織定量解析(ステレオロジー) 母性剥奪ラット海馬定量解析ストレス成人病素因周生期ストレス海馬脳発達可塑性母子間相互作用 maternal deprivation hippocampal neurons perinatal stress brain development neurotrophic factors BDNF mRNA Real-time PCR stereology

研究成果

[雑誌論文] Application of the physical dissector to central nervous system : estimation of the total number of neurons in the subdivisions of the rat hippocampus

Miki T, Satriotomo I, Li H-P, Matsumoto Y, He G, Yokoyam T, Lee K-Y, Bedi KS, Takeuchi Y 2005

[雑誌論文] Application of the physical disector to central nervous system : estim ation of the total number of neurons in the subdivisions of the rat hippocampus

Takanori Miki et al. 2005

[雑誌論文] Multiple defects in the formation of rat cortical axonal pathways following prenatal X-ray irradiation.

Li H-P, Honma S, Miki T, Takeuchi Y, Takeuchi K, Kawano H. 2005

[雑誌論文] Relationship between cerebral interstitial levels of amino acids and phosphorylation potential during secondary energy failure in hypoxic-ischemicnewborn piglets

Kusaka et al. 2004

[雑誌論文] Relationship between cerebral interstitial levels of amino acids and phosphorylation potential during secondary energy failure in hypoxic-ischemic newborn piglets.

Kusaka T, Matsuura S, Fujikawa Y, Okubo K, Kawada K, Namba M, Okada H, Imai T, Isobe K, Itoh S. 2004

[雑誌論文] Relationship between cerebral interstitial levels of amino acids and phosphorylation potential during secondary energy failure in hypoxic-ischemic newborn pialets

Takashi Kusaka et al. 2004

[雑誌論文] Early maternal deprivation induces alterations in brain-derived neurotrophic factor expression in the developing rat hippocampus.

Kuma H, Miki T, Matsumoto Y, Gu H, Li HP, Kusaka T, Satriotomo I, Okamoto H, Yokoyama T, Bedi KB, Onishi S, Suwaki H, Takeuchi Y. 2004

[雑誌論文] Excessive testosterone treatment and castration induce reactive astrocytes and fos immunoreactivity in suprachiasmatic nucleus of mice.

Satriotomo I, Miki T, Gonzalez D, Matsumoto Y, Li HP, Gu H, Takeuchi Y. 2004

[雑誌論文] Parabrachial inputs to Fos-immunoreactive neurons in the lateral central nucleus of amygdala activated by hypotension : a light and electron microscopic study in the rat.

Takeuchi Y, Xie Q, Miki T, Matsumoto Y, Satriotomo I, Li HP, Gu H. 2004

[雑誌論文] Effects of age and alcohol exposure during early life on pyramidal cell numbers in the CA1-CA3 region of the rat hippocampus

Takanori Miki et al. 2004

[雑誌論文] Effects of age and alcohol exposure during early life on pyramidal cell numbers in the CA1-CA3 region of the rat hippocampus.

Miki T, Harris SJ, Wilce PA, Takeuchi Y, Bedi KS. 2004

[雑誌論文] Effects of age and alcohol exposure during early life on pyramidal cell numbers in the CA1-CA3 region of the rat hippocampus.

Miki et al. 2004

[雑誌論文] Kindling of the ventral tegmental area induces supersensitivity in the central dopamine system

Takemi Watanabe et al. 2004

[雑誌論文] Kindling of the ventral tegmental area induces supersensitivity in the central dopamine system

Watanabe et al. 2004

[雑誌論文] Kindling of the ventral tegmental area induces supersensitivity in the central dopamine system.

Watanabe T, Morimoto K, Nakamura M, Hirao T, Ninomiya T, Ando N, Suwaki H. 2004

[雑誌論文] Activation of the visual cortex in newborn infants under natural sleep using multichannel near-infrared spectroscopy.

Kusaka T, Okubo K, Nagano K, Yasuda S, Kawada K, Imai T, Isobe K, Itoh S. 2003

[雑誌論文] Activation of the visual cortex in newborn infants under natural sleep using multichannel near-infrared spectroscopy

Takashi Kusaka et al. 2003

[雑誌論文] The effects of alcohol exposure during early life on neuron numbers in the rat hippocampus : I) hilus neurons and granule cells.

Takanori Miki et al. 2003

[雑誌論文] Colocalization of taurine and glial fibrillary acidic protein immunoreactivity in mouse hippocampus induced by short-term ethanol exposure.

Sakurai T, Miki T, Li HP, Miyatake A, Satriotomo I, Takeuchi Y. 2003

[雑誌論文] Effects of alcohol exposure during early life on neuron numbers in the rat hippocampus. I. Hilus neurons and granule cells.

Miki T, Harris SJ, Wilce PA, Takeuchi Y, Bedi KS. 2003

[雑誌論文] Quantification of cerebral oxygenation by full-spectrum near-infrared spectroscopy using a two-point method.

Kusaka T, Isobe K, Nagano K, Okubo K, Yasuda S, Kondo M, Itoh S, Hirao K, Onishi S. 2002

[雑誌論文] Quantification of cerebral oxygenation by full spectrum near infrared spectroscopy with a two-point method

Takashi Kusaka et al. 2002

[雑誌論文] The effect of the timing of prenatal X-irradiation on Purkinje cell numbers in rat cerebellum.

Li HP, Miki T, Gu H, Satriotomo I, Matsumoto Y, Kuma H, Gonzalez D, Bedi KS, Suwaki H, Takeuchi Y. 2002