トップ研究者を探す二酸化窒素様活性窒素種の心血管系組織からの発生機序とその制御に関する研究

二酸化窒素様活性窒素種の心血管系組織からの発生機序とその制御に関する研究

KAKEN 科学研究費助成事業データベース で見る
研究課題番号 KAKENHI-PROJECT-14370120
研究種目 基盤研究(B)
研究分野 医学
社会医学
衛生学
研究機関 金沢大学
代表研究者 荻野 景規
研究分担者 神林 康弘
研究分担者 加藤 昌志
研究分担者 中村 裕之
研究分担者 信國 好俊
研究期間 開始年月日 2002/4/1
研究期間 終了年度 2004
研究ステータス 完了 (2004/4/1)
配分額(合計) 14,100,000 (直接経費 :14,100,000)
配分額(履歴) 2004年度:2,900,000 (直接経費 :2,900,000)
2003年度:5,000,000 (直接経費 :5,000,000)
2002年度:6,200,000 (直接経費 :6,200,000)
キーワード ペルオキシダーゼ
ニトロチロシン
心臓
免疫組織化学
心筋梗塞
ヘモグロビン
ミオグロビン
ミエロペルオキシダーゼ
心筋細胞
亜硝酸
NO
虚血
チトクロームC
ミクロペルオキシダーゼ
ニトロ化
免疫組織
HPLC
好酸球
peoxidase
nitrotyrosine
heart
immunohistochemistry
myocardial infarction
homoglobin
myoglobin
myeloperoxidase

研究成果

[雑誌論文] Intranasal mite allergen induces allergic asthma-like responses in NC/Nga mice.

Shibamori M, Ogino K, Kambayashi Y, Ishiyama H 2006

[雑誌論文] Intranasal mite allergen induces allergic asthma-like responses in NC/Nga mice.

Shibamori, M., Ogino, K., Kambayashi, Y., Ishiyama, H. 2006

[雑誌論文] Kinobeon A, purified from safflower's culture cells, is a novel and potent single oxygen quencher.

Kambayashi Y, Takekoshi S, Nakano M, Shibamori M, Hitomi Y, Ogino K 2005

[雑誌論文] Reactive nitrogen species formation in eosinophils and imbalance in nitric oxide metabolism are involved in atopic dermatitis-like skin lesions in NC/Nga mice.

Kubo, M., Kambayashi, Y., Takemoto, K., Okuda, J., Muto, M., Ogino K. 2005

[雑誌論文] Reactive nitrogen species formation in eosinophils and imbalance in nitric oxoxide metabolism are involved in atopic dermatitis-like skin lesions in NC/Nga mice.

Kubo M, Kambayashi Y, Takemoto K, Okuda J, Muto M, Ogino K 2005

[雑誌論文] Kinobeon A, purified from safflower's culture cells, is a novel and potent singlet oxygen quencher.

Kambayashi, Y., Takekoshi, S., Nakano, M., Shibamori, M., Hitomi, Y., Ogino, K. 2005

[雑誌論文] Association of single nucleotide polymorphisms in the eosinophil peroxidase gene with Japanese cedar pollinosis.

Nakamura, H., Higashikawa, F., Miyagawa, K., Nobukuni, Y., Endo, T., Imai, T., Ozasa, K., Motohashi, Y., Matsuzaki, I., Sasahara, S., Hatta, K., Ogino, k., Eboshida, A. 2004

[雑誌論文] Association of single nucleotide polymorphisms in the eosinophil peroxidase gene with Japanese cedar pollinosis.

Nakamura H, Higashikawa F, Miyagawa K, Nobukuni Y, Endo T, Imai T, Ozasa K, Motohashi Y, Matsuzaki I, Sasahara S, Hatta K, Ogino K, Eboshida A. 2004

[雑誌論文] Induction of myeloperoxidase and nitrotyrosine formation in a human leukemia cell line, EoL-1.

Kodama N, Kambayashi Y, Kubo M, Yoneyama S, Nobukuni Y, Nakamura H, Ogino K. 2004

[雑誌論文] Induction of myeloperoxidase and nitrotyrosine formation in a human eosinophilic leukemia cell line, Eol-1.

Kodama N, Kambaayashi Y, Kubo M, Yoneyama S, Nobukuni Y, Nakamura H, Ogino K 2004

[雑誌論文] c-Kit-targeting immunotherapy for hereditary melanoma in a mouse model.

Kato M, Takeda K, Kawamoto Y, Tsuzuki T, Hossain K, Tamakoshi A, Kunisada T, Kambayashi Y, Ogino K, Suzuki H, Takahashi M, Nakashima I. 2004

[雑誌論文] Induction of myeloperoxidase and nitrotyrosine formation in a human eosinophilic leukemia cell line, EoL-1.

Kodama, N., Kambayashi, Y., Kubo, M., Yoneyama, S., Nobukuni, Y., Nakamura, H., Ogino, K. 2004

[雑誌論文] Reestimation of Cypridina luciferin analogues (MCLA) as a chemiluminescence probe to detect active oxygen species-cationary note for use of MCLA

Kambayashi Y, Ogino K 2003

[雑誌論文] High contribution contrast between the genes of eosinophil peroxidase and IL-4 receptor alpha-chain in Japanese cedar pollinosis.

Nakamura H, Miyagawa K, Ogino K, Endo T, Imai T, Ozasa K, Motohashi Y, Matsuzaki I, Sasahara S, Hatta K, Eboshida A 2003

[雑誌論文] High contribution contrast between the genes of eosinophil peroxidase and IL-4 receptor α-chain in Japanese cedar pollinosis.

Nakamura H, Miyagawa K, Ogino K, Endo T, Imai T, Ozasa K, Motohashi Y, Matsuzaki I, Sasahara S, Hatta K, Eboshida A. 2003

[雑誌論文] Formation of superoxide anion during ferrous ion-catalyzed decomposition of linoleic acid hydroperoxide under aerobic condition.

Kambayashi, Y., Tero-Kubota, S., Yamamoto, Y., Kato, M., Nakano, M., Yagi, K., Ogino, K. 2003

[雑誌論文] High contribution contrast between the genes of eosinophil peroxidase and IL-4 receptor alpha-chain in Japanese cedar pollinosis.

Nakamura, H., Miyagawa, K., Ogino, K., Endo, T., Imai, T., Ozasa, K., Motohashi, Y., Matsuzaki, I., Sasahara, S., Hatta, K., Eboshida, A. 2003

[雑誌論文] Reestimation of Cypridina luciferin analogs (MCLA) as a chemiluminescence probe to detect active oxygen species -cautionary note for use of MCLA.

Kambayashi, Y., Ogino, K. 2003

[雑誌論文] Reactive Nitrogen Species Formation in Eosinophils and Imbalance in Nitric Oxide Metabolism Are Involved in Atopic Dermatitis-Like Skin Lesions in NC/Nga Mice.

Kubo M, Kambayashi Y, Takemoto K, Okuda J, Muto M, Ogino K.