トップ研究者を探す普遍的な再生原理の探求と応用

普遍的な再生原理の探求と応用

KAKEN 科学研究費助成事業データベース で見る
研究課題番号 KAKENHI-ORGANIZER-22124001
研究種目 新学術領域研究(研究領域提案型)
研究分野
研究機関 京都大学
代表研究者 阿形 清和
連携研究者 野地 澄晴
連携研究者 梅園 良彦
連携研究者 横山 仁
連携研究者 遠藤 哲也
連携研究者 柴田 典人
研究期間 開始年月日 2010/4/1
研究期間 終了年度 2015
研究ステータス 完了 (2015/4/1)
配分額(合計) 160,940,000 (直接経費 :123,800,000、間接経費 :37,140,000)
配分額(履歴) 2015年度:3,900,000 (直接経費 :3,000,000、間接経費 :900,000)
2014年度:23,400,000 (直接経費 :18,000,000、間接経費 :5,400,000)
2013年度:20,020,000 (直接経費 :15,400,000、間接経費 :4,620,000)
2012年度:24,830,000 (直接経費 :19,100,000、間接経費 :5,730,000)
2011年度:39,390,000 (直接経費 :30,300,000、間接経費 :9,090,000)
2010年度:49,400,000 (直接経費 :38,000,000、間接経費 :11,400,000)
キーワード 再生
再生医療
器官形成
トランスクリプトーム
数理モデル
イモリ
カエル
プラナリア
コオロギ
関節再生

研究成果

[雑誌論文] Involvement of dachshund and Distal-less in distal pattern formation of the cricket leg during regeneration

Y. Ishimaru, T. Nakamura, T. Bando, Y. Matsuoka, H. Ohuchi, S. Noji and T. Mito 2015

[雑誌論文] Light and abscisic acid independently regulated FaMYB10 in Fragaria x ananassa fruit

Y. Kadomura-Ishikawa, K. Miyawaki, A. Takahashi, T. Masuda and S. Noji 2015

[雑誌論文] Novel role of hnRNP-A2/B1 in modulating aryl hydrocarbon receptor ligand sensitivity

S. W. Cho, K. I. Suzuki, Y. Miura, T. Miyazaki, M. Nose, H. Iwata and E. Y. Kim 2014

[雑誌論文] An extended steepness model for leg-size determination based on Dachsous/Fat trans-dimer system.

Yoshida H, Bando T, Mito T, Ohuchi H, Noji S. 2014

[雑誌論文] Highly efficient targeted mutagenesis in one-cell mouse embryos mediated by the TALEN and CRISPR/Cas systems

A. Yasue, S. N. Mitsui, T. Watanabe, T. Sakuma, S. Oyadomari, T. Yamamoto, S. Noji, T. Mito and E. Tanaka 2014

[雑誌論文] 3D image reconstruction of histopathological structure of atherosclerotic plaque using a novel technique with film tomography

T. Hiro, T. Takayama, H. Haruta, M. Mitsumori, K. Tanaka, J. Kawanabe, S. Noji and A. Hirayama 2014

[雑誌論文] Gene knockout by targeted mutagenesis in a hemimetabolous insect, the two-spotted cricket Gryllus bimaculatus, using TALENs

T. Watanabe, S. Noji and T. Mito 2014

[雑誌論文] Correlation of fibroblast growth factor 21 serum levels with metabolic parameters in Japanese subjects

Q. R. Jin, Y. Bando, K. Miyawaki, Y. Shikama, C. Kosugi, N. Aki, M. Funaki and S. Noji 2014

[雑誌論文] Effectiveness of cationic liposome-mediated local delivery of myostatin-targeting small interfering RNA in vivo

H. Mori, N. Kawai, N. Kinouchi, N. Hichijo, T. Ishida, E. Kawakami, S. Noji and E. Tanaka 2014

[学会発表] Targeted genome editing in the cricket, Gryllus bimaculatus, using CRISPR/Cas9 system

Watanabe, T., Matsuoka, Y., Noji, S. and Mito, T 2014

[雑誌論文] コオロギ脚再生の分子メカニズム

板東哲哉、三戸太郎、野地澄晴、大内淑代 2014

[学会発表] 原始的発生様式をとる昆虫の胚発生過程におけるポリコーム遺伝子群によるホメオティック遺伝子発現の制御機能

松岡佑児,板東哲哉,渡辺崇人,野地澄晴,三戸太郎 2014

[雑誌論文] Lowfat, a mammalian Lix1 homologue, regulates leg size and growth under the Dachsous/Fat signaling pathway during tissue regeneration.

Bando Tetsuya 2011

[雑誌論文] Regulation of leg size and shape: involvement of the Dachsous-fat signaling pathway.

Bando Tetsuya 2011

[学会発表] Regeneration Biology in Japan

K.Agata, Y.Umesono, S.Noji, T.Endo, H.Yokoyama 2011

[学会発表] Regulation of leg size and shape : involvement of the Dachsous-Fat signaling pathway

S.Noji, T.Bando, T.Mito, T.Nakamura, H.Ohuchi 2011

[学会発表] Lowfat regulates leg size and growth under the Dachsous/Fat signaling during regeneration in Gryllus bimaculatus

T.Bando, Y.Hamada, T.Nakamura, T.Mito, H.Ohuchi, S.Noji 2011

[学会発表] Involvement of Dachsous/Fat signaling pathway in regulation of leg size and shape during cricket legregeneration

T.Bando, T.Nakamura, T.Mito, H.Ohuchi, S.Noji 2010

[学会発表] Functions of Polycomb group gene in regulation of Hox gene expression in a primitive mode of insect embryogenesis in the cricket Gryllus bimaculatus

Yuji Matsuoka, Tetsuya Bando, Takahito Watanabe, Sumihare Noji, Taro Mito 0

[学会発表] Molecular Mechanisms underlying Regeneration of Insect Legs: Involvement of the JAK-STAT and Dachsous-Fat Signaling Pathways

Noji Sumihare

[学会発表] Molecular mechanisms underlying insect leg regeneration: from wound healing to leg size determination

野地澄晴

[学会発表] Targeted gene disruption in the cricket, Gryllus bimaculatus, using CRISPR/Cas9 system

Takahito Watanabe, Yuji Matsuoka, Taro Mito, Sumihare Noji 0

[学会発表] Mechanisms underlying regeneration of the cricket leg, based on an extended steepness model

Tetsuya Bando, Yoshiyasu Ishimaru, Hiroshi Yoshida, Taro Nakamura, Taro Mito, Hideyo Ohuchi, Sumihare Noji, 0

[学会発表] In vivo study of Msx1 gene in mice using CRISPR/Cas system

Silvia Mitsui, Akihiro Yasue, Issei Imoto, Seiichi Oyadomari, Sumihare Noji, Taro Mito, Eiji Tanaka 0

[学会発表] Epigenetic regulation of gene expressions via methylation on histone H3 27th lysine residue during leg regeneration

Yoshimasa Hamada, Tetsuya Bando, Taro Mito, Kenji Tomioka, Sumihare Noji, Hideyo Ohuchi 0