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木下倫子

徳島大学

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2024年11月22日更新

職名: 助教
電話: 研究者総覧に該当データはありませんでした。
電子メール: michiko-kinoshita@tokushima-u.ac.jp
学歴: 2006/3: 徳島大学医学部医学科卒業
????/??: 徳島大学大学院医科学教育部医学専攻博士課程
学位: 博士(医学) (徳島大学)
学士(医学) (徳島大学) (2006年3月)
職歴・経歴: 2010/5: 徳島大学特任助教, 病院 (-2011.6.)
2019/6: 徳島大学助教, 病院

専門分野・研究分野: 医学 (Medicine)

研究者総覧で最新データを確認する

2024年11月22日更新

専門分野・研究分野: 医学 (Medicine)
担当経験のある授業科目: 研究者総覧に該当データはありませんでした。
指導経験: 1人 (博士)

研究者総覧で最新データを確認する

2024年11月22日更新

専門分野・研究分野: 医学 (Medicine)

研究テーマ: 研究者総覧に該当データはありませんでした。

著書

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論文

Matsumoto Yako, Michiko Kinoshita, Yoshinobu Tomiyama and Katsuya Tanaka :
Earthquake Preparedness for Operating Room Staff: Lessons Learned From Experiences and the Literature,
Anesthesia & Analgesia, 2024.

(徳島大学機関リポジトリ): ● Metadata: 119645
(出版サイトへのリンク): ● Publication site (DOI): 10.1213/ANE.0000000000007250
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 39504302; ● Search Scopus @ Elsevier (PMID): 39504302; ● Search Scopus @ Elsevier (DOI): 10.1213/ANE.0000000000007250

(徳島大学機関リポジトリ: 119645, DOI: 10.1213/ANE.0000000000007250, PubMed: 39504302) Sekiguchi Ryo, Michiko Kinoshita, Yoko Sakai and Katsuya Tanaka :
Anesthetic management of a patient with mandibular hypoplasia, deafness, progeroid features, lipodystrophy syndrome: a case report,
JA Clinical Reports, 64, 2024.

(徳島大学機関リポジトリ): ● Metadata: 119632
(出版サイトへのリンク): ● Publication site (DOI): 10.1186/s40981-024-00747-8
(文献検索サイトへのリンク): ● Search Scopus @ Elsevier (DOI): 10.1186/s40981-024-00747-8

(徳島大学機関リポジトリ: 119632, DOI: 10.1186/s40981-024-00747-8) Matsumoto Yako, Yoko Sakai, Michiko Kinoshita, Nakaji Yoshimi, Takahashi Rikako and Katsuya Tanaka :
Impact of anesthesiologist experience on neuraxial anesthesia outcomes in cesarean sections,
Minerva Anestesiologica, Vol.90, No.10, 864-71, 2024.

(徳島大学機関リポジトリ): ● Metadata: 119619
(出版サイトへのリンク): ● Publication site (DOI): 10.23736/S0375-9393.24.18154-0
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 39283168; ● Search Scopus @ Elsevier (PMID): 39283168; ● Search Scopus @ Elsevier (DOI): 10.23736/S0375-9393.24.18154-0

(徳島大学機関リポジトリ: 119619, DOI: 10.23736/S0375-9393.24.18154-0, PubMed: 39283168) Hiroya Endo, Ryo Sekiguchi, Michiko Kinoshita and Katsuya Tanaka :
Peripheral venous dilation using flow-mediated dilation response: A randomized crossover study,
The Journal of Vascular Access, 2024.

(徳島大学機関リポジトリ): ● Metadata: 119596
(出版サイトへのリンク): ● Publication site (DOI): 10.1177/11297298241273642
(文献検索サイトへのリンク): ● Search Scopus @ Elsevier (DOI): 10.1177/11297298241273642

(徳島大学機関リポジトリ: 119596, DOI: 10.1177/11297298241273642) Rikako Takahashi, Yoko Sakai, Michiko Kinoshita, Yako Matsumoto, Yoshimi Nakaji and Katsuya Tanaka :
Quantitative and calculated estimated blood loss in cesarean deliveries for twin and singleton pregnancies: a retrospective analysis,
Journal of Anesthesia, 2024.

(要約): This study retrospectively assessed blood loss during cesarean deliveries for twin and singleton pregnancies using two distinct methods, quantitative estimation measured during cesarean sections and hematocrit-based calculated estimation. We included scheduled cesarean deliveries for twin or singleton pregnancies at ≥ 34 weeks of gestation. Quantitative blood loss was recorded based on the blood volume in the graduated collector bottle and by weighing the blood-soaked textiles during cesarean sections. The blood loss was calculated using the change in hematocrit levels before and after the cesarean delivery. We evaluated 403 cases including 44 twins and 359 singletons. Quantitative blood loss during cesarean section was significantly higher in twin pregnancies than that in singleton pregnancies (1117 [440] vs 698 [378] mL; p < 0.001). However, no significant differences were observed in the calculated blood loss between the two groups on the day after delivery (487 mL [692 mL] vs 507 mL [522 mL]; p = 0.861). On post-delivery days 4-5, twin pregnancies were associated with a significantly higher calculated blood loss than singleton pregnancies (725 [868] mL vs 444 [565] mL, p = 0.041). Although a significant moderate correlation between quantitative and calculated blood loss was observed in singleton pregnancies (r = 0.473, p < 0.001), no significant correlation was observed between twin pregnancies (r = 0.053, p = 0.735). Quantitative blood loss measurements during cesarean section may be clinically insufficient in twin pregnancies. Incorporating blood tests and continuous assessments are warranted for enhanced blood loss evaluation, especially in twin pregnancies, owing to the risk of persistent bleeding.
(徳島大学機関リポジトリ): ● Metadata: 119485
(出版サイトへのリンク): ● Publication site (DOI): 10.1007/s00540-024-03370-0
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 38963564; ● Search Scopus @ Elsevier (PMID): 38963564; ● Search Scopus @ Elsevier (DOI): 10.1007/s00540-024-03370-0

(徳島大学機関リポジトリ: 119485, DOI: 10.1007/s00540-024-03370-0, PubMed: 38963564) Sarara Mutoh, Michiko Kinoshita, Yuki Maeda and Katsuya Tanaka :
Ketamine as an Alternative Anesthetic for Augmenting Seizure Durations During Electroconvulsive Therapy: A Retrospective Observational Study,
The Journal of ECT, Vol.40, No.2, 134-139, 2024.

(要約): Electroconvulsive therapy (ECT) is highly effective for severe psychiatric disorders; however, short seizure durations may lead to ineffective therapy. This retrospective study aimed to examine the risks and benefits of switching to ketamine anesthesia to augment seizure durations during an acute course of ECT. We included 33 patients who underwent ketamine anesthesia due to suboptimal seizures during an acute course of ECT. We assessed seizure duration, stimulus dose, hemodynamic variability, and postseizure complications before and after switching to ketamine. Age was significantly associated with suboptimal seizures during ECT (P = 0.040). After switching to ketamine, 32 patients (97%) experienced prolonged seizure duration. Ketamine significantly prolonged both electroencephalogram and motor seizure durations with a mean difference of 34.6 seconds (95% confidence interval [CI], 26.4-42.7 seconds; P < 0.001) and 26.6 seconds (95% CI, 19.6-33.6 seconds; P < 0.001), respectively. It also significantly reduced stimulus dose (mean difference, -209.5 mC [95% CI, -244.9 to -174.1 mC]; P < 0.001). In addition, maximum changes in systolic blood pressure and heart rate during ECT sessions significantly increased with ketamine (mean difference, 27.2 mm Hg [95% CI, 12.0-42.4 mm Hg; P = 0.001]; 25.7 beats per minute [95% CI, 14.5-36.8 beats per minute; P < 0.001], respectively). Patients reported more headaches with ketamine (P = 0.041). Our results provide evidence that ketamine as an alternative anesthetic can augment seizure durations in specific patients experiencing suboptimal seizures during an acute course of ECT. However, its use requires greater attention to circulatory management and postseizure complications.
(キーワード): augmentation / alternative anesthetic / electroconvulsive therapy / ketamine / seizure duration
(徳島大学機関リポジトリ): ● Metadata: 118832
(出版サイトへのリンク): ● Publication site (DOI): 10.1097/YCT.0000000000000981
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 38109337; ● Search Scopus @ Elsevier (PMID): 38109337; ● Search Scopus @ Elsevier (DOI): 10.1097/YCT.0000000000000981

(徳島大学機関リポジトリ: 118832, DOI: 10.1097/YCT.0000000000000981, PubMed: 38109337) 木下倫子, 鈴木奈央, 田中克哉 :
日本麻酔科学会年次学術集会における一般演題数の推移と要因,
麻酔, Vol.73, No.4, 233-237, 2024年.

(出版サイトへのリンク): ● Publication site (DOI): 10.18916/masui.2024040006
(文献検索サイトへのリンク): ● CiNii @ 国立情報学研究所 (CRID): 1390299760190538752; ● Search Scopus @ Elsevier (DOI): 10.18916/masui.2024040006

(DOI: 10.18916/masui.2024040006, CiNii: 1390299760190538752) Michiko Kinoshita, Makoto Kinoshita, Rikako Takahashi, Sarara Mutoh, Nami Kakuta and Katsuya Tanaka :
The Safety and Strategies for Reinitiating Electroconvulsive Therapy After ECT-Induced Takotsubo Cardiomyopathy: A Case Report and Systematic Review.,
The Journal of ECT, Vol.39, No.3, 185-192, 2023.

(要約): Electroconvulsive therapy-induced TCM is more likely to cause cardiogenic shock than nonperioperative cases; nevertheless, it has good prognosis. Cautious reinitiation of ECT after TCM recovery is possible. Further studies are required to determine preventive measures for ECT-induced TCM.
(キーワード): electroconvulsive therapy / takotsubo cardiomyopathy / systematic review
(徳島大学機関リポジトリ): ● Metadata: 118060
(出版サイトへのリンク): ● Publication site (DOI): 10.1097/YCT.0000000000000905
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 36897138; ● Summary page in Scopus @ Elsevier: 2-s2.0-85169185042

(徳島大学機関リポジトリ: 118060, DOI: 10.1097/YCT.0000000000000905, PubMed: 36897138, Elsevier: Scopus) Yuta Uemura, Michiko Kinoshita, Yoko Sakai and Katsuya Tanaka :
Hemodynamic impact of ephedrine on hypotension during general anesthesia: a prospective cohort study on middle-aged and older patients,
BMC Anesthesiology, Vol.23, No.1, 283, 2023.

(要約): Ephedrine is a mixed α- and β-agonist vasopressor that is frequently used for the correction of hypotension during general anesthesia. β-responsiveness has been shown to decrease with age; therefore, this study aimed to determine whether aging would reduce the pressor effect of ephedrine on hypotension during general anesthesia. Seventy-five patients aged ≥ 45 years were included in this study, with 25 patients allocated to each of the three age groups: 45-64 years, 65-74 years, and ≥ 75 years. All patients received propofol, remifentanil, and rocuronium for the induction of general anesthesia, followed by desflurane and remifentanil. Cardiac output (CO) was estimated using esCCO technology. Ephedrine (0.1 mg/kg) was administered for the correction of hypotension. The primary and secondary outcome measures were changes in the mean arterial pressure (MAP) and CO, respectively, at 5 min after the administration of ephedrine. RESULTS: The administration of ephedrine significantly increased MAP (p < 0.001, mean difference: 8.34 [95% confidence interval (CI), 5.95-10.75] mmHg) and CO (p < 0.001, mean difference: 7.43 [95% CI, 5.20-9.65] %) across all groups. However, analysis of variance revealed that the degree of elevation of MAP (F [2, 72] = 0.546, p = 0.581, η = 0.015 [95% CI, 0.000-0.089]) and CO (F [2, 72] = 2.023, p = 0.140, η = 0.053 [95% CI, 0.000-0.162]) did not differ significantly among the groups. Similarly, Spearman's rank correlation and multiple regression analysis revealed no significant relation between age and the changes in MAP or CO after the administration of ephedrine. The administration of ephedrine significantly increased MAP and CO; however, no significant correlation with age was observed in patients aged > 45 years. These findings suggest that ephedrine is effective for the correction of hypotension during general anesthesia, even in elderly patients. UMIN-CTR (UMIN000045038; 02/08/2021).
(キーワード): Aged / Middle Aged / Humans / Ephedrine / Prospective Studies / Remifentanil / Hemodynamics / Hypotension / Vasoconstrictor Agents / Anesthesia, General
(徳島大学機関リポジトリ): ● Metadata: 118532
(出版サイトへのリンク): ● Publication site (DOI): 10.1186/s12871-023-02244-4
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 37608253; ● Summary page in Scopus @ Elsevier: 2-s2.0-85168706206

(徳島大学機関リポジトリ: 118532, DOI: 10.1186/s12871-023-02244-4, PubMed: 37608253, Elsevier: Scopus) Michiko Kinoshita, Takahashi Mina, Katsuya Tanaka and Yoko Sakai :
Authorship by gender in anesthesiology journals: a retrospective cross-sectional study for Japan,
Journal of Anesthesia, Vol.37, No.3, 364-370, 2023.

(要約): Although it is important to recognize gender disparities in publishing to achieve gender diversity, women's authorship in Japan remains unclear. Therefore, this study aimed to investigate the percentage and analyze the trends of articles authored and published in anesthesiology journals by Japanese female authors. The genders of the first and last authors affiliated with Japanese institutions were surveyed in the Journal of Anesthesia (JA) (1990, 1995, and 2000-2022) and 11 international anesthesiology journals (2010-2022). We included 845 and 819 original research articles from JA in the analyses of the first and last authors, respectively. The proportion of female first authors significantly increased from 41 (11.7%) out of 351 before 2009 to 119 (24.1%) out of 494 after 2010 (p < 0.001). The proportion of female last authors was 11 (3.3%) out of 335 before 2009 and 22 (4.5%) out of 484 after 2010, respectively, with no significant difference (p = 0.470). We included 624 and 572 original research articles from international anesthesiology journals in the analyses of first and last authors, respectively. Among these, there were 134 (21.5%) and 23 (4.0%) female first and last authors, respectively. These proportions in international anesthesiology journals did not significantly differ from those in JA (p = 0.334, p = 0.789, respectively). The percentage of female first authors has increased, commensurate with the percentage of female anesthesiologists. However, the percentage of female last authors has not increased and remains low in Japan.
(徳島大学機関リポジトリ): ● Metadata: 117926
(出版サイトへのリンク): ● Publication site (DOI): 10.1007/s00540-023-03165-9
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 36688988; ● Search Scopus @ Elsevier (PMID): 36688988; ● Search Scopus @ Elsevier (DOI): 10.1007/s00540-023-03165-9

(徳島大学機関リポジトリ: 117926, DOI: 10.1007/s00540-023-03165-9, PubMed: 36688988) Ryo Sekiguchi, Michiko Kinoshita, Ryosuke Kawanishi, Nami Kakuta, Yoko Sakai and Katsuya Tanaka :
Comparison of hemodynamics during induction of general anesthesia with remimazolam and target-controlled propofol in middle-aged and elderly patients: a single-center, randomized, controlled trial.,
BMC Anesthesiology, 2023.

(要約): MAP decreased after induction of anesthesia in both groups, without significant differences between the groups (- 41.1 [16.4] mmHg and - 42.8 [10.8] mmHg in remimazolam and propofol groups, respectively; mean difference: 1.7 [95% confidence interval: - 8.2 to 4.9]; p = 0.613). Furthermore, HR, CO, and SV decreased after induction in both groups, without significant differences between the groups. Remimazolam group had significantly shorter time until loss of consciousness than propofol group (1.7 [0.7] min and 3.5 [1.7] min, respectively; p < 0.001). However, MAP, HR, CO, and SV were not significantly different between the groups despite adjusting time until loss of consciousness as a covariate. Seven (35%) and 11 (55%) patients in the remimazolam and propofol groups, respectively, experienced hypotension (MAP < 65 mmHg over 2.5 min), without significant differences between the groups (p = 0.341).
(キーワード): Adult / Aged / Middle Aged / Humans / Propofol / Piperidines / Hemodynamics / Anesthesia, General / Hypotension / Unconsciousness / Anesthetics, Intravenous
(徳島大学機関リポジトリ): ● Metadata: 117916
(出版サイトへのリンク): ● Publication site (DOI): 10.1186/s12871-023-01974-9
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 36624371; ● Search Scopus @ Elsevier (PMID): 36624371; ● Search Scopus @ Elsevier (DOI): 10.1186/s12871-023-01974-9

(徳島大学機関リポジトリ: 117916, DOI: 10.1186/s12871-023-01974-9, PubMed: 36624371) Michiko Kinoshita, Sarara Mutoh, Asuka Kasai, Ryosuke Kawanishi and Katsuya Tanaka :
General Anesthesia in a Patient With Neuronal Intranuclear Inclusion Disease: A Case Report.,
A&A Practice, Vol.16, No.10, 2022.

(要約): Neuronal intranuclear inclusion disease (NIID) is a progressive neurodegenerative disease with diverse clinical manifestations, including dementia and muscle weakness. We summarize anesthetic considerations in reporting general anesthesia for a 58-year-old man with bladder dysfunction and cerebellar ataxia who was diagnosed with NIID. The patient developed postinduction hypotension relevant to autonomic neuropathy. The potential risks, such as prolonged reaction to neuromuscular blocking agent, postoperative delirium, and worsening of NIID-related symptoms, were also considered. The responsiveness to anesthetics may vary widely from case t case. As the number of NIID cases increases, a better understanding of NIID is needed.
(出版サイトへのリンク): ● Publication site (DOI): 10.1213/XAA.0000000000001633
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 36599032; ● Search Scopus @ Elsevier (PMID): 36599032; ● Search Scopus @ Elsevier (DOI): 10.1213/XAA.0000000000001633

(DOI: 10.1213/XAA.0000000000001633, PubMed: 36599032) Michiko Kinoshita, Yoko Sakai, Kimiko Katome, Tomomi Matsumoto, Shizuka Sakurai, Yuka Jinnouchi and Katsuya Tanaka :
Transition in eye gaze as a predictor of emergence from general anesthesia in children and adults: a prospective observational study.,
BMC Anesthesiology, Vol.22, No.1, 2022.

(要約): In children, eye-gaze transition was observed significantly earlier than other physical-behavioral responses during emergence from general anesthesia and seemed to reflect emergence from anesthesia. In contrast, observation of eye gaze was not a useful indicator of emergence from anesthesia in adults.
(徳島大学機関リポジトリ): ● Metadata: 117915
(出版サイトへのリンク): ● Publication site (DOI): 10.1186/s12871-022-01867-3
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 36253763; ● Search Scopus @ Elsevier (PMID): 36253763; ● Search Scopus @ Elsevier (DOI): 10.1186/s12871-022-01867-3

(徳島大学機関リポジトリ: 117915, DOI: 10.1186/s12871-022-01867-3, PubMed: 36253763) Michiko Kinoshita, Yuki Ishikawa, Ryo Sekiguchi, Miyuki Matsuda and Katsuya Tanaka :
Impact of surgical masks on fraction of inspired oxygen during oxygen therapy depends on the type of oxygen masks and respiratory conditions: volunteer- and simulation-based studies.,
Journal of Anesthesia, Vol.36, No.5, 633-641, 2022.

(要約): was measured using a simulator that reproduced spontaneous breathing. RR was 12 or 24 bpm, and the tidal volume (Tv) was 300, 500, or 700 mL. The effect of oxygen mask fitting conditions was also examined. The primary outcome measure was FIO
(キーワード): Carbon Dioxide / Humans / Masks / Oxygen / Oxygen Inhalation Therapy / Respiratory Rate / Volunteers
(徳島大学機関リポジトリ): ● Metadata: 117917
(出版サイトへのリンク): ● Publication site (DOI): 10.1007/s00540-022-03083-2
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 35711009; ● Search Scopus @ Elsevier (PMID): 35711009; ● Search Scopus @ Elsevier (DOI): 10.1007/s00540-022-03083-2

(徳島大学機関リポジトリ: 117917, DOI: 10.1007/s00540-022-03083-2, PubMed: 35711009) Michiko Kinoshita, Yasuhito Honda, Yoko Sakai, Yoshinobu Tomiyama and Katsuya Tanaka :
Elevated tryptase in vancomycin-induced red man syndrome.,
Journal of Anesthesia, Vol.35, No.5, 773-774, 2021.

(キーワード): Erythema / Humans / 症候群 (syndrome) / Tryptases / Vancomycin
(出版サイトへのリンク): ● Publication site (DOI): 10.1007/s00540-021-02985-x
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 34387746; ● Summary page in Scopus @ Elsevier: 2-s2.0-85112453285

(DOI: 10.1007/s00540-021-02985-x, PubMed: 34387746, Elsevier: Scopus) Chiaki Murakami, Hiroaki Kawano, Michiko Kinoshita, Akio Kondo and Masaya Inoue :
Effects of Nicorandil Versus Nitroglycerin on Arterial Oxygenation During Two-Lung Ventilation and One-Lung Ventilation in Patients With Risk Factors for Myocardial Ischemia: A Prospective, Randomized, Double-Blind Study.,
Journal of Cardiothoracic and Vascular Anesthesia, Vol.33, No.3, 702-709, 2018.

(要約): at TLV (479.7 ± 57.1 v 408.2 ± 70.9 mmHg, p < 0.001); and at 5 minutes (344.8 ± 85.1 v 282.6 ± 85.8 mmHg, p = 0.012), 20 minutes (215.7 ± 103.0 v 158.2 ± 74.5 mmHg, p = 0.027), and 30 minutes (198.8 ± 103.5 v 147.5 ± 64.1 mmHg, p = 0.039) after OLV was significantly higher in the nicorandil group than in the nitroglycerin group.
(出版サイトへのリンク): ● Publication site (DOI): 10.1053/j.jvca.2018.05.022
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 30054187; ● Search Scopus @ Elsevier (PMID): 30054187; ● Search Scopus @ Elsevier (DOI): 10.1053/j.jvca.2018.05.022

(DOI: 10.1053/j.jvca.2018.05.022, PubMed: 30054187) Hiroaki Kawano, Michiko Kinoshita, Akio Kondo, Yasuhito Yamada and Masaya Inoue :
TORSADES DE POINTES ASSOCIATED WITH TAKOTSUBO CARDIOMYOPATHY IN AN ANOREXIA NERVOSA PATIENT DURING EMERGENCE FROM GENERAL ANESTHESIA.,
Middle East Journal of Anaesthesiology, Vol.23, No.5, 557-561, 2016.

(要約): Takotsubo cardiomyopathy, also known as stress-induced cardiomyopathy, is a disease in which the patient exhibits transient, reversible left ventricular dysfunction that is triggered by physical or emotional stress. Prolongation of QT interval, a risk factor for arrhythmia and sudden death, has been reported to be prevalent among patients with Takotsubo cardiomyopathy and is also observed in those with severe anorexia nervosa. In this report, we describe the rare case of a 30-year-old female patient with anorexia nervosa who developed Torsades de Pointes associated with Takotsubo cardiomyopathy during emergence from general anesthesia for emergency exploratory laparotomy.
(キーワード): Adult / Anesthesia, General / Anorexia Nervosa / Electrocardiography / Female / Humans / Laparotomy / Takotsubo Cardiomyopathy / Torsades de Pointes
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 27487642; ● Search Scopus @ Elsevier (PMID): 27487642

(PubMed: 27487642) Michiko Kinoshita, Yasuo M. Tsutsumi, Kohei Fukuta, Asuka Kasai and Katsuya Tanaka :
Isoflurane-induced postconditioning via mitochondrial calcium-activated potassium channels.,
The Journal of Medical Investigation : JMI, Vol.63, No.1-2, 80-84, 2016.

(要約): Activation of the mitochondrial calcium-activated potassium (mKCa) channel reportedly confers resistance to myocardial ischemic stress. However, the role of the mKCa channel in postconditioning induced by volatile anesthetic remains unclear. Male Japanese white rabbits underwent coronary artery occlusion for 30 min followed by reperfusion for 3 h. Volatile anesthetic, isoflurane, was administered at 3 min prior to reperfusion for 5 min. Rabbits were injected with the mKCa channel blocker, iberiotoxin, or the mKCa channel opener, NS1619, at 8 min prior to reperfusion. Myocardial infarct size and the area at risk (AAR) were measured at the end of the experiment. Isoflurane significantly reduced infarct size (23.0 ± 9.8% of the AAR, P<0.05) compared with the control (44.0 ± 9.1%). Iberiotoxin abolished the cardioprotective impact of isoflurane (43.0 ± 11.6%), while iberiotoxin alone exerted no effect on infarct size (45.0 ± 9.5%). NS1619 and isoflurane/NS1619 both significantly reduced infarct size (21.0 ± 10.3% and 19.0 ± 8.8%, respectively, P<0.05 vs control group), but isoflurane/NS1619 showed no additional benefits compared with isoflurane alone. These results indicate that activation of the mKCa channel contribute isoflurane-induced postconditioning.
(徳島大学機関リポジトリ): ● Metadata: 111158
(出版サイトへのリンク): ● Publication site (DOI): 10.2152/jmi.63.80
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 27040058; ● Summary page in Scopus @ Elsevier: 2-s2.0-84962157655

(徳島大学機関リポジトリ: 111158, DOI: 10.2152/jmi.63.80, PubMed: 27040058, Elsevier: Scopus) Hiroaki Kawano, Naohiro Ohshita, Kimiko Katome, Takako Kadota, Michiko Kinoshita, Yayoi Matsuoka, Yasuo M. Tsutsumi, Shinji Kawahito, Katsuya Tanaka and Shuzo Oshita :
[Effects of a novel method of anesthesia combining propofol and volatile anesthesia on the incidence of postoperative nausea and vomiting in patients undergoing laparoscopic gynecological surgery].,
Revista Brasileira de Anestesiologia, Vol.66, No.1, 12-18, 2015.

(要約): We investigated the effects of a novel method of anesthesia combining propofol and volatile anesthesia on the incidence of postoperative nausea and vomiting in patients undergoing laparoscopic gynecological surgery. Patients were randomly divided into three groups: those maintained with sevoflurane (Group S; n = 42), propofol (Group P; n = 42), or combined propofol and sevoflurane (Group PS; n = 42). We assessed complete response (no postoperative nausea and vomiting and no rescue antiemetic use), incidence of nausea and vomiting, nausea severity score, vomiting frequency, rescue antiemetic use, and postoperative pain at 2 and 24h after surgery. The number of patients who exhibited a complete response was greater in Groups P and PS than in Group S at 0-2h (74%; 76% and 43%; respectively, p = 0.001) and 0-24h (71%; 76%, and 38%; respectively, p < 0.0005). The incidence of nausea at 0-2h (Group S = 57%; Group P = 26% and Group PS = 21%; p = 0.001) and 0-24h (Group S = 62%; Group P = 29% and Group PS = 21%; p < 0.0005) was also significantly different among groups. However, there were no significant differences among groups in the incidence or frequency of vomiting or rescue antiemetic use at 0-24h. Combined propofol and volatile anesthesia during laparoscopic gynecological surgery effectively decreases the incidence of postoperative nausea.
(出版サイトへのリンク): ● Publication site (DOI): 10.1016/j.bjan.2014.07.006
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 25896644; ● Summary page in Scopus @ Elsevier: 2-s2.0-84952982793

(DOI: 10.1016/j.bjan.2014.07.006, PubMed: 25896644, Elsevier: Scopus) Hiroaki Kawano, Sawa Manabe, Tomomi Matsumoto, Eisuke Hamaguchi, Michiko Kinoshita, Fumihiko Tada and Shuzo Oshita :
Comparison of intraoperative blood loss during spinal surgery using either remifentanil or fentanyl as an adjuvant to general anesthesia.,
BMC Anesthesiology, Vol.13, No.1, 2013.

(要約): The remifentanil group exhibited significantly lower intraoperative arterial BP than the fentanyl group. Intraoperative blood loss was also significantly lower in the remifentanil group (125 ± 67 mL vs. 165 ± 82 mL, P = 0.035).
(徳島大学機関リポジトリ): ● Metadata: 119224
(出版サイトへのリンク): ● Publication site (DOI): 10.1186/1471-2253-13-46
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 24304964; ● Search Scopus @ Elsevier (PMID): 24304964; ● Search Scopus @ Elsevier (DOI): 10.1186/1471-2253-13-46

(徳島大学機関リポジトリ: 119224, DOI: 10.1186/1471-2253-13-46, PubMed: 24304964) Kayo Hirose, Yasuo M. Tsutsumi, Rie Tsutsumi, Masayuki Shono, Erika Katayama, Michiko Kinoshita, Katsuya Tanaka and Shuzo Oshita :
Role of the O-linked -N-acetylglucosamine in the cardioprotection induced by isoflurane.,
Anesthesiology, Vol.115, No.5, 955-962, 2011.

(要約): Cardiac protection by volatile anesthetic-induced preconditioning and ischemic preconditioning have similar signaling pathways. Recently, it was reported that augmentation of protein modified with O-linked -N-acetylglucosamine (O-GlcNAc) contributes to cardiac protection. This study investigated the role of O-GlcNAc in cardiac protection induced by anesthetic-induced preconditioning. O-GlcNAc-modified proteins were visualized by immunoblotting. Tolerance against ischemia or reperfusion was tested in vivo (n = 8) and in vitro (n = 6). The opening of the mitochondrial permeability transition pore (mPTP) upon oxidative stress was examined in myocytes treated with calcein AM (n = 5). Coimmunoprecipitation and enzymatic labeling were performed to detect the mitochondrial protein responsible for the mPTP opening. Isoflurane treatment and the consequent augmentation of O-GlcNAc concentrations reduced the infarct size (26 ± 5% [mean ± SD], P < 0.001) compared with the control. The protective effect of O-GlcNAc was eliminated in the group pretreated with the O-GlcNAc transferase inhibitor alloxan (39 ± 5%, P < 0.001). Myocyte survival also showed the same result in vitro. Formation of the mPTP was abrogated in the isoflurane-treated cells (86 ± 4%, P < 0.001) compared with the control and alloxan-plus-isoflurane-treated cells (57 ± 7%, P < 0.001). Coimmunoprecipitation and enzymatic labeling studies revealed that the O-GlcNAc-modified, voltage-dependent anion channel restained the mPTP opening. Isoflurane induced O-GlcNAc modification of mitochondrial voltage-dependent anion channel. This modification inhibited the opening of the mPTP and conferred resistance to ischemia-reperfusion stress.
(キーワード): Acetylglucosamine / Anesthetics, Inhalation / Animals / Cell Survival / Heart / Ischemic Preconditioning, Myocardial / Isoflurane / Male / Mice / Mice, Inbred C57BL / Mitochondrial Membrane Transport Proteins / Myocardial Reperfusion Injury / Voltage-Dependent Anion Channels
(出版サイトへのリンク): ● Publication site (DOI): 10.1097/ALN.0b013e31822fcede
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 21876430; ● Search Scopus @ Elsevier (PMID): 21876430; ● Search Scopus @ Elsevier (DOI): 10.1097/ALN.0b013e31822fcede

(DOI: 10.1097/ALN.0b013e31822fcede, PubMed: 21876430) 福田浩平, 堤保夫, 曽我朋宏, 木下倫子, 田中克哉 :
脳血管芽腫摘出術と褐色細胞腫摘出術を緊急で行ったvon Hippel-Lindau病の麻酔経験,
日本臨床麻酔学会誌, Vol.31, No.5, 884-887, 2011年.

(キーワード): von Hippel-Lindau病 / 褐色細胞腫 / 血管芽腫 / 高用量レミフェンタニル / 緊急手術
(徳島大学機関リポジトリ): ● Metadata: 117911
(出版サイトへのリンク): ● Publication site (DOI): 10.2199/jjsca.31.884
(文献検索サイトへのリンク): ● CiNii @ 国立情報学研究所 (CRID): 1390001204759730304; ● Search Scopus @ Elsevier (DOI): 10.2199/jjsca.31.884

(徳島大学機関リポジトリ: 117911, DOI: 10.2199/jjsca.31.884, CiNii: 1390001204759730304) Nami Kakuta, Yasuo M. Tsutsumi, Yousuke T. Horikawa, Hiroaki Kawano, Michiko Kinoshita, Katsuya Tanaka and Shuzo Oshita :
Neurokinin-1 receptor antagonism, aprepitant, effectively diminishes post-operative nausea and vomiting while increasing analgesic tolerance in laparoscopic gynecological procedures.,
The Journal of Medical Investigation : JMI, Vol.58, No.3-4, 246-251, 2011.

(要約): Post-operative nausea and vomiting (PONV) remains the most frequently reported patient complaint after anesthesia. Aprepitant is the first neurokinin-1(NK1) receptor antagonism available for use as an antiemetic. We investigated whether aprepitant can effectively decrease PONV in patients undergoing laparoscopic gynecological surgery. Sixty four patients receiving general anesthesia for laparoscopic gynecological surgery were randomly assigned to either receive a preoperative dose of 80 mg aprepitant or no drug. Efficacy was assessed in 2 and 24 hours after surgery. Primary and secondary endpoints were analyzed for the time intervals 0-2 hours (acute phase) and 2-24 hours (delayed phase). Vomiting, nausea, use of rescue anti-emetic, and visual analog scale (VAS) were assessed. Nausea was assessed on a 4-point scale, from 0 to 3. Sixty patients participated in the study. At acute phase, PONV was present in both control and NK1 group and were 63% and 43% respectively. The severity of nausea was much less in the NK1 group. PONV prevalence at delayed phase was present in control but absent in NK1 group 27% vs. 0%, respectively. The amount of pain medication used by patients in the NK1 group was significantly less for diclofenac and pentazocine suggesting increase pain tolerance. Neurokinin-1 receptor antagonism effectively lowered PONV increased pain tolerance, and expedited recovery in patients undergoing laparoscopic gynecological surgery.
(キーワード): Adult / Antiemetics / Female / Gynecologic Surgical Procedures / Humans / Laparoscopy / Middle Aged / Morpholines / Pain Measurement / Pain Threshold / Postoperative Nausea and Vomiting / Receptors, Neurokinin-1
(徳島大学機関リポジトリ): ● Metadata: 83838
(出版サイトへのリンク): ● Publication site (DOI): 10.2152/jmi.58.246
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 21921426; ● Search Scopus @ Elsevier (PMID): 21921426; ● Search Scopus @ Elsevier (DOI): 10.2152/jmi.58.246

(徳島大学機関リポジトリ: 83838, DOI: 10.2152/jmi.58.246, PubMed: 21921426) Yasuo M. Tsutsumi, Rie Tsutsumi, Kazuaki Mawatari, Yutaka Nakaya, Michiko Kinoshita, Katsuya Tanaka and Shuzo Oshita :
Compound K, a metabolite of ginsenosides, induces cardiac protection mediated nitric oxide via Akt/PI3K pathway.,
Life Sciences, Vol.88, No.15-16, 725-729, 2011.

(要約): Compound K (C-K; 20-O-D-glucopyranosyl-20(S)-protopanaxadiol) is a novel ginsenoside metabolite formed by intestinal bacteria and does not occur naturally in ginseng. In this study, we investigated whether administration of C-K has protective effects on myocardial ischemia-reperfusion injury and its potential mechanisms.
(キーワード): Androstadienes / Animals / カルシウム (calcium) / Ginsenosides / Immunoblotting / 男性 (male) / Mice / Mice, Inbred C57BL / Mitochondria, Heart / Myocardial Infarction / Myocardial Reperfusion Injury / 一酸化窒素 (nitric oxide) / Nitric Oxide Synthase Type III / Phosphatidylinositol 3-Kinases / Proto-Oncogene Proteins c-akt
(出版サイトへのリンク): ● Publication site (DOI): 10.1016/j.lfs.2011.02.011
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 21338613; ● Summary page in Scopus @ Elsevier: 2-s2.0-79953283184

(DOI: 10.1016/j.lfs.2011.02.011, PubMed: 21338613, Elsevier: Scopus) Katsuya Tanaka, Takashi Kawano, Yasuo M. Tsutsumi, Michiko Kinoshita, Nami Kakuta, Kayo Hirose, Masakazu Kimura and Shuzo Oshita :
Differential effects of propofol and isoflurane on glucose utilization and insulin secretion.,
Life Sciences, Vol.88, No.1-2, 96-103, 2011.

(要約): Volatile anesthetics, such as isoflurane, reverse glucose-induced inhibition of pancreatic adenosine triphosphate-sensitive potassium (K(ATP)) channel activity, resulting in reduced insulin secretion and impaired glucose tolerance. No previous studies have investigated the effects of intravenous anesthetics, such as propofol, on pancreatic K(ATP) channels. We investigated the cellular mechanisms underlying the effects of isoflurane and propofol on pancreatic K(ATP) channels and insulin secretion.
(キーワード): アデノシン三リン酸 (adenosine triphosphate) / Anesthetics, Inhalation / Anesthetics, Intravenous / Animals / Dose-Response Relationship, Drug / グルコース (glucose) / Glucose Tolerance Test / インスリン (insulin) / Islets of Langerhans / Isoflurane / KATP Channels / 男性 (male) / Membrane Potentials / Patch-Clamp Techniques / Propofol / Rabbits / Rats
(出版サイトへのリンク): ● Publication site (DOI): 10.1016/j.lfs.2010.10.032
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 21056586; ● Summary page in Scopus @ Elsevier: 2-s2.0-78650519087

(DOI: 10.1016/j.lfs.2010.10.032, PubMed: 21056586, Elsevier: Scopus)

MISC

Michiko Kinoshita, Mizuki Komasaka and Katsuya Tanaka :
ChatGPTs performance on JSA-certified anesthesiologist exam,
Journal of Anesthesia, 2023.

(キーワード): ChatGPT / GenerativeAI / 大規模言語モデル (large scale language model) / Anesthesiology
(徳島大学機関リポジトリ): ● Metadata: 118717
(出版サイトへのリンク): ● Publication site (DOI): 10.1007/s00540-023-03275-4
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 37902835; ● Search Scopus @ Elsevier (PMID): 37902835; ● Search Scopus @ Elsevier (DOI): 10.1007/s00540-023-03275-4

(徳島大学機関リポジトリ: 118717, DOI: 10.1007/s00540-023-03275-4, PubMed: 37902835) Michiko Kinoshita, Yoko Sakai and Katsuya Tanaka :
Relative publication output and international collaboration in anaesthesiology and pain medicine: a bibliometric analysis from 1996 to 2021,
British Journal of Anaesthesia, Vol.131, No.2, e53-e55, 2023.

(出版サイトへのリンク): ● Publication site (DOI): 10.1016/j.bja.2023.05.014
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 37330311; ● Summary page in Scopus @ Elsevier: 2-s2.0-85165099943

(DOI: 10.1016/j.bja.2023.05.014, PubMed: 37330311, Elsevier: Scopus)

総説・解説: 研究者総覧に該当データはありませんでした。
講演・発表: Takahashi Rikako, Yoko Sakai, Matsumoto Yako, Nakaji Yoshimi, Michiko Kinoshita and Katsuya Tanaka :
Quantitative and Calculated Estimated Blood Loss in Caesarean Sections: A Retrospective Comparative Analysis between Twin and Singleton Pregnancies,
Euroanesthesia 2024, May 2024. Yako Matsumoto, Michiko Kinoshita, Yoshinobu Tomiyama and Katsuya Tanaka :
Protecting Intraoperative Patients In Time Of Natural DisastersPast Experiences And Lessons Learned: A Scoping Review,
The Anesthesiology Annual Meeting 2023, San Francisco, Oct. 2023. Ryo Sekiguchi, Michiko Kinoshita, Ryosuke Kawanishi, Nami Kakuta, Yoko Sakai and Katsuya Tanaka :
Comparison Between Hemodynamics Of Remimazolam And Propofol During General Anesthesia: A Randomized Study,
The Anesthesiology Annual Meeting, Oct. 2022. Michiko Kinoshita, Yoko Sakai, Kimiko Katome, Tomomi Matsumoto, Yuka Jinnouchi, Noriko Niki, Shizuka Sakurai, Yoshiko Yoshida and Katsuya Tanaka :
The transition in the eye gaze is a helpful predictor of emergence from general anesthesia with sevoflurane combined with remifentanil in children, but not adults, --- A prospective observational study ---,
The Annual Meeting of the American Society of Anesthesiologists, WEB, Oct. 2020. Mai Morimoto, Katsuya Tanaka, Michiko Kinoshita, Noriko Kambe, Ryosuke Kawanishi, Katsuyoshi Kume, Naohiro Oshita, Yasuo M. Tsutsumi and Shuzo Oshita :
Effects of new developed mask for novel mask holding on the quality of mask ventilation and the pressure between face and mask.,
The American Society of Anesthesiologist Annual Meeting, San Francisco, Oct. 2013. Michiko Kinoshita, Katsuya Tanaka, Yasuo Tsutsumi and Shuzo Oshita :
Role of calcium-activated potassium channel and cAMP-dependent protein kinase on isflurane-induced postconditoning.,
American Society of Anesthesiologists 2011 Annual Meeting, Chicago, Oct. 2011. Katsuya Tanaka, Michiko Kinoshita, Yasuo Tsutsumi, Kaori Takata and Shuzo Oshita :
Simvastatin restores anesthetic postconditioning in the presence of hyperglycemia in vivo rabbits.,
American Society of Anesthesiologists 2011 Annual Meeting, Chicago, Oct. 2011. Michiko Kinoshita, Katsuya Tanaka, Yasuo Tsutsumi, Hirose Kayo and Shuzo Oshita :
The effect of the novel mask ventilation technique on airway management.,
The Annual Meeting of the American Society of Anesthesiologists, San Diego, California, Oct. 2010. Michiko Kinoshita, Katsuya Tanaka, Jinnouchi Yuka, Yasuo Tsutsumi and Shuzo Oshita :
Dose dependent effects of remifentanil on perioperative immune-inflammtory response in patients.,
The Annual Meeting of the American Society of Anesthesiologists, San Diego, California, Oct. 2010. Hirose Kayo, Shuzo Oshita, Michiko Kinoshita, Katsuya Tanaka and Yasuo Tsutsumi :
The role of O-linked -N-acetylglucosamine in the cardiac protection induced by isoflurane.,
The Annual Meeting of the American Society of Anesthesiologists, San Diego, California, Oct. 2010. 木下倫子, 酒井陽子, 田中克哉 :
日本麻酔科学会年次学術集会の講演者の性別割合,
日本麻酔科学会中国・四国支部第61回学術集会, 2024年9月. 遠藤寛也, 関口諒, 木下倫子, 田中克哉 :
血流依存性血管拡張反応を応用した末梢静脈径拡張の検討 :ランダム化クロスオーバー試験,
日本麻酔科学会第71回学術集会, 2024年6月. 中路佳美, 酒井陽子, 高橋里加子, 松本弥子, 木下倫子, 田中克哉 :
帝王切開術における脊髄くも膜下麻酔から胎児娩出までの時間に影響を与える因子 :後方視的分析,
日本麻酔科学会第71回学術集会, 2024年6月. 松本弥子, 酒井陽子, 木下倫子, 田中克哉 :
Impact of Anesthesiologists' Experience on Anesthetic Management in Cesarean Section,
第11回日本区域麻酔学会学術集会, 2024年4月. 関口諒, 鈴木奈央, 木下倫子, 田中克哉 :
携帯型ディスポーザブル注入ポンプの投与精度に関する検討 —機械式ポンプとバルーン式ポンプの比較—,
第41回日本麻酔 · 集中治療テクノロジー学会, 2023年11月. 手塚信裕, 酒井陽子, 木下倫子, 池添照代, 藤本理恵子, 田中克哉 :
特定行為研修修了看護師が全身麻酔中に行う追加連絡の検討,
日本麻酔科学会中国・四国支部第60回学術集会, 2023年9月. 駒坂みずき, 木下倫子, 田中克哉 :
麻酔科専門分野におけるChatGPTの能力検証:麻酔科専門医認定筆記試験の正答,
日本麻酔科学会中国・四国支部第60回学術集会, 2023年9月. 鈴木奈央, 木下倫子, 田中克哉 :
日本麻酔科学会年次学術集会における一般演題数の変化とその要因,
日本麻酔科学会中国・四国支部第60回学術集会, 2023年9月. 石川雄樹, 木下倫子, 田中克哉 :
呼気終末陽圧が麻酔回路からのセボフルラン排出速度に与える影響,
日本麻酔科学会中国・四国支部第60回学術集会, 2023年9月. 木下倫子, 田中克哉, 酒井陽子 :
顕示的比較優位(RCA)指数を用いた麻酔・疼痛医学分野における論文数の計量書誌学的分析,
日本麻酔科学会第70回学術集会, 2023年6月. 木下倫子, 高橋未奈, 田中克哉, 酒井陽子 :
麻酔科学における日本女性の学術活動状況と推移,
日本麻酔科学会第70回学術集会, 2023年6月. 関口諒, 木下倫子, 田中克哉 :
携帯型ディスポーザブル注入ポンプの投与速度の精度に関する検討,
日本麻酔科学会第70回学術集会, 2023年6月. 植村勇太, 常城あゆみ, 木下倫子, 関口諒, 田中克哉 :
高齢者におけるエフェドリンの昇圧効果および循環動態変化の検討:前向き観察研究,
日本麻酔科学会第69回学術集会, 2022年6月. 前田卓也, 篠原光治, 武藤さら良, 木下倫子, 川西良典, 田中克哉 :
神経核内封入体病患者の麻酔経験,
日本麻酔科学会中国・四国支部第59回学術集会, 2022年. 高橋里加子, 武藤さら良, 松田みゆき, 木下倫子, 角田奈美, 田中克哉 :
修正型電気けいれん療法(mECT)誘発性たこつぼ型心筋症の再発予防のための麻酔管理:症例報告と文献レビュー,
日本麻酔科学会中国・四国支部第59回学術集会, 2022年. 武藤さら良, 河原富也, 木下倫子, 酒井陽子, 田中克哉 :
修正型電気痙攣療法におけるケタミン麻酔の有用性と問題点,
日本麻酔科学会第68回学術集会, 2021年. 関口諒, 河原富也, 木下倫子, 石川雄樹, 酒井陽子, 田中克哉 :
サージカルマスクがオープンタイプの酸素マスクを用いた酸素療法に与える影響:ランダム化，クロスオーバー，単盲検試験,
日本麻酔科学会第68回学術集会, 2021年. 松田みゆき, 木下倫子, 関口諒, 石川雄樹, 酒井陽子, 田中克哉 :
酸素マスクの種類と呼吸パターンがサージカルマスク併用の酸素療法に与える影響:シミュレーターを用いた研究,
日本麻酔科学会中国・四国支部第58回学術集会, 2021年. 岩佐みゆき, 西京子, 佐藤功志, 浅井孝仁, 前田拓也, 中村昌史, 門田宗之, 田中久美子, 河北直也, 武田美佐, 藤永裕之, 近藤明男, 木下倫子, 酒井陽子, 田中克哉, 安倍正博, 西村匡司, 香美祥二 :
メディカルゾーン(MZ)重点研修プログラムにおける麻酔化融合研修,
第261回徳島医学会学術集会, 2020年8月. 吉田佳子, 木下倫子, 松本朋美, 香留希実子, 酒井陽子, 田中克哉 :
吸入麻酔薬とレミフェンタニルを用いた小児全身麻酔からの覚醒と眼位の変化の関係,
日本麻酔科学会第67回学術集会, 2020年6月. 曾我部洋平, 木下倫子, 陣内由佳, 箕田直治, 田中克哉 :
抗Jra抗体を有する血友病B保因者の乳房部分切除術の麻酔経験,
日本麻酔科学会中国・四国第54回学術集会, 2017年9月. 堤保夫, 田中克哉, 曽我朋宏, 神邊紀子, 木下倫子, 大下修造 :
敗血症マウスにおける分岐鎖アミノ酸投与がタンパク合成に及ぼす影響,
第59回日本麻酔科学会, 2012年6月. 門田尚子, 堤保夫, 大下修造, 河野裕明, 笠井飛鳥, 木下倫子, 角田奈美, 田中克哉 :
術後嘔気・嘔吐に対する選択的ニューロキニン1受容体拮抗薬の有効性,
日本臨床麻酔学会第31回大会, 2011年11月. 角田奈美, 堤保夫, 木下倫子, 田中克哉, 河野裕明, 大下修造, 大下修造 :
選択的ニューロキニン1受容体拮抗型制吐剤が術後嘔気嘔吐に及ぼす影響,
日本麻酔科学会第58回学術集会, 2011年5月. 金村朋美, 田中克哉, 木下倫子, 門田尚子, 堤保夫, 大下修造, 大下修造 :
Grip and Lift法とEC法の2種類のマスク換気中にマスクと顔面の間にかかる圧分布の検討,
日本麻酔科学会第58回学術集会, 2011年5月. 木下倫子, 田中克哉, 堤保夫, 福田浩平, 真鍋佐和, 大下修弘 :
ソフルランのポストコンディショニング効果におけるCa2+依存性K+チャネルとcAMP依存性プロテインキナーゼの役割,
日本麻酔科学会第58回学術集会, 2011年5月. 廣瀬佳代, 田中克哉, 木下倫子, 堤保夫, 大下修弘 :
イソフルランによる心筋保護効果におけるO-Linked β-N-Acetylglucosamineとミトコンドリア機能,
日本麻酔科学会第58回学術集会, 2011年5月. 木下倫子, 田中克哉, 野村佳世, 濱口英佑, 大下修造 :
新しいマスク換気法とマスクの開発∼より安全な麻酔導入に向けて∼,
日本麻酔科学会第57回学術集会, 2010年6月. 堤保夫, 廣瀬佳代, 木下倫子, 角田奈美, 田中克哉, 大下修造 :
吸入麻酔薬による遅延型プレコンディショニングの細胞膜ドメインに及ぼす影響,
第57回日本麻酔科学会, 2010年6月. 木下倫子, 田中克哉, 河野崇, 陣内由佳, 大下修造 :
高用量レミフェンタニルによる全身麻酔がストレス反応に及ぼす影響,
日本麻酔科学会第57回学術集会, 2010年6月. 田中克哉, 河野崇, 堤保夫, 木下倫子, 廣瀬佳代, 大下修造 :
麻酔薬が膵臓β細胞のATP感受性K+チャネルに及ぼす影響,
第57回日本麻酔科学会, 2010年6月. 角田奈美, 田中克哉, 木下倫子, 河野崇, 堤保夫, 大下修造 :
プロポフォールとイソフルランがブドウ糖負荷試験に及ぼす影響,
第57回日本麻酔科学会, 2010年6月.

研究会・報告書: 研究者総覧に該当データはありませんでした。

特許: 田中克哉, 木下倫子, 大下修造 : GL用麻酔用マスク, (2010年8月), (2012年3月), 特許第2010-191931号.
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補助金・競争的資金: 吸入麻酔薬と近赤外線の併用は高齢モデルにおいて心保護効果を増強するか？ (研究課題/領域番号: 20K17814 )
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2024年11月22日更新

専門分野・研究分野: 医学 (Medicine)
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受賞: 2023年6月, 日本麻酔科学会第70回学術集会最優秀演題賞 (社団法人日本麻酔科学会)
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2024年11月16日更新

研究者番号: 90532218

所属（現在）: 2024/4/1 : 徳島大学, 病院, 助教

所属（過去の研究課題 情報に基づく）*注記: 2020/4/1 – 2022/4/1 : 徳島大学, 病院, 助教

審査区分/研究分野: 研究代表者

小区分55050:麻酔科学関連

キーワード: 研究代表者

吸入麻酔薬 / 近赤外線 / 心筋保護 / 近位赤外線 / 心保護 / 虚血再灌流 / 心筋梗塞

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