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住谷さつき

徳島大学

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2024年12月23日更新

職名: 教授
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電子メール: satsuki@clin.med.tokushima-u.ac.jp
学歴: 1990/3: 徳島大学医学部医学科卒業
学位: 博士(医学) (徳島大学) (2007年2月)
職歴・経歴: 〜: 徳島大学助手, 大学院ヘルスバイオサイエンス研究部 (-2007.3.)
2007/4: 徳島大学講師, 病院 (-2009.11.)
2009/12: 徳島大学准教授, 大学院ヘルスバイオサイエンス研究部 (-2015.3.)
2015/4: 徳島大学准教授, 大学院医歯薬学研究部 (-2015.6.)
2015/7: 徳島大学教授, 特別修学支援室 (-2016.3.)
2016/4: 徳島大学教授, 大学院医歯薬学研究部 (-2017.3.)
2017/4: 徳島大学教授, 特別修学支援室 (-2019.3.)
2019/4: 徳島大学教授, キャンパスライフ健康支援センター

専門分野・研究分野: 医学 (Medicine)

研究者総覧で最新データを確認する

2024年12月23日更新

専門分野・研究分野: 医学 (Medicine)
担当経験のある授業科目: 医学心理行動学 (共通教育)
精神医学特論(保健医療分野に関する理論と支援の展開) (大学院)
身体・精神・発達障害へのサポート (共通教育)
指導経験: 研究者総覧に該当データはありませんでした。

研究者総覧で最新データを確認する

2024年12月23日更新

専門分野・研究分野: 医学 (Medicine)

研究テーマ: 研究者総覧に該当データはありませんでした。

著書

住谷さつき :
CHAPTER 5 神経症性・ストレス関連性障害および身体表現性障害,
株式会社中外医学社, 2016年6月. 住谷さつき :
強迫性障害,
南々社, 2015年8月. 瀧川裕美子, 住谷さつき :
身体表現性障害,
株式会社中外医学社, 2015年6月. 住谷さつき :
神経症性，ストレス関連性障害および身体表現性障害,
株式会社中外医学社, 2015年6月. 住谷さつき :
強迫性障害,
株式会社医学書院, 2015年. 住谷さつき, 大森哲郎 :
統合失調症や気分障害のMRの最新知見バイオマーカー(Ⅲ),
株式会社星和書店, 2015年. 住谷さつき :
子どもの心の処方箋ガイド, --- 強迫性障害 ---,
株式会社中山書店, 東京, 2014年4月. 住谷さつき :
発達障害,
医歯薬出版株式会社, 2014年. 住谷さつき :
精神・心療内科疾患とは,
医歯薬出版株式会社, 2014年. 住谷さつき :
不眠,
医歯薬出版株式会社, 2014年. 住谷さつき :
神経症性，ストレス関連性障害および身体表現性障害,
2011年3月. 住谷さつき, 大森哲郎 :
強迫性障害ハンドブック, --- 強迫性障害ニューロサイエンス ---,
2005年. 住谷さつき, 大森哲郎 :
強迫性障害の研究(5), --- 5．OCDの薬物治療応答性と臨床特徴について ---,
株式会社星和書店, 東京, 2004年. 谷岡哲也, 高坂要一郎, 真野元四郎, 瀧川薫, 多田敏子, 永峰勲, 橋本文子, 松下恭子, 住谷さつき :
精神障害をやさしく理解するQ&A253,
日総研, 名古屋, 2003年4月. 住谷さつき, 大森哲郎 :
精神医学症候群ー統合失調症と周縁疾患などー, --- Ⅲ 神経症性障害，ストレス関連障害，および身体表現性障害 3)強迫性障害の治療 ---,
日本臨牀社, 2003年.

論文

Takeo Tominaga, Masahito Tomotake, Tomoya Takeda, Yoshinori Ueoka, Tsunehiko Tanaka, Shinya Watanabe, Naomi Kameoka, Masahito Nakataki, Shusuke Numata, Yumiko Izaki, Satsuki Sumitani, Hiroko Kubo, Yasuhiro Kaneda and Tetsuro Ohmori :
Predictors of life skills in people with schizophrenia,
The Journal of Medical Investigation : JMI, Vol.67, No.1,2, 75-82, 2020.

(要約): Objective : The purpose of the present study is to examine clinical factors related to life skills in people with schizophrenia. Method : The participants were 51 stabilized outpatients with schizophrenia. Their mean age was 38.91 (SD = 10.73) years. Life skills were assessed using the Life skills profile (LSP). Cognitive function was evaluated with the Measurement and Treatment Research to Improve Cognition in Schizophrenia Consensus Cognitive Battery (MCCB). Clinical symptoms were assessed using the Positive and Negative Syndrome scale (PANSS), the Calgary Depression Scale for Schizophrenia (CDSS) and the Drug-Induced Extrapyramidal Symptoms Scale (DIEPSS). Results : Cognitive function was not correlated with the LSP scores at all. Among clinical symptoms, scores of the PANSS positive and negative syndrome scales, the CDSS, and the DIEPSS had negative correlations with the LSP total score and the subscales. Stepwise regression analyses showed that the CDSS and PANSS negative syndrome scale scores were independent predictors of the LSP total score and two of the subscales. Conclusions : These results indicate that cognitive function is not associated with life skills but clinical symptoms such as depressive and negative symptoms have considerable impacts on life skills in people with schizophrenia. J. Med. Invest. 67 : 75-82, February, 2020.
(徳島大学機関リポジトリ): ● Metadata: 114756
(出版サイトへのリンク): ● Publication site (DOI): 10.2152/jmi.67.75
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 32378622; ● Summary page in Scopus @ Elsevier: 2-s2.0-85084203721

(徳島大学機関リポジトリ: 114756, DOI: 10.2152/jmi.67.75, PubMed: 32378622, Elsevier: Scopus) Naomi Kameoka, Satsuki Sumitani and Tetsuro Ohmori :
Behavioral and psychological symptoms of dementia (BPSD) and care burden : Examination in the facility staff for elderly residents.,
The Journal of Medical Investigation : JMI, Vol.67, No.3.4, 236-239, 2020.

(要約): Purpose : We investigated the cognitive function, behavioral and psychological symptoms of dementia (BPSD), and activities of daily living (ADLs) of elderly individuals admitted in care facilities. Moreover, the factors affecting the care burden experienced by facility staffs were examined. Method : 24 care facilities for elderly individuals participated in the study. The Revised Hasegawa Dementia Scale (HDS-R), Japanese version of the Neuropsychiatric Inventory (NPI), and Crichton Geriatric Behavioral Rating Scale (CGBRS) were used to evaluate cognitive function, BPSD, and ADL, respectively. The short Japanese version of the Zarit Burden Interview was used to assess the care burden. A multiple regression analysis was conducted with data obtained from 464 elderly individuals who fulfilled all the scales. Results : The care burden was correlated to the scores of HDS-R, but not with those of dysphoria/depression and disinhibition of NPI, restlessness of CGBRS, and subjective mood of CGBRS (R2 = 0.309, p < 0.005). Conclusion : Dysphoria/depression, disinhibition, restlessness, and subjective mood, but not cognitive decline, have an effect on the care burden experienced by facility staffs who manage elderly individuals. These results indicated that the appropriate diagnosis and treatment of BPSD are important in reducing the burden of facility staffs. J. Med. Invest. 67 : 236-239, August, 2020.
(徳島大学機関リポジトリ): ● Metadata: 115410
(出版サイトへのリンク): ● Publication site (DOI): 10.2152/jmi.67.236
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 33148894; ● Search Scopus @ Elsevier (PMID): 33148894; ● Search Scopus @ Elsevier (DOI): 10.2152/jmi.67.236

(徳島大学機関リポジトリ: 115410, DOI: 10.2152/jmi.67.236, PubMed: 33148894) 住谷さつき :
長期にわたり気分の変動と摂食障害の症状が連動した双極性障害の1例鑑別診断と病因の相互作用に関する考察,
精神神經學雜誌, Vol.121, No.10, 790-798, 2019年.

(キーワード): 双極性障害 / 摂食障害 / 神経性無食欲症 / 躁状態 / 気分安定薬 / bipolar disorder / eating disorder / anorexia nervosa / manic state / mood stabilizer
(文献検索サイトへのリンク): ● CiNii @ 国立情報学研究所 (CRID): 1520854805705822208

(CiNii: 1520854805705822208) Tomoya Takeda, Masahito Nakataki, Masashi Ohta, S Hamatani, K Matsuura, R Yoshida, Naomi Kameoka, Takeo Tominaga, Hidehiro Umehara, Makoto Kinoshita, Shinya Watanabe, Shusuke Numata, Satsuki Sumitani and Tetsuro Ohmori :
Negative and positive self-thoughts predict subjective quality of life in people with schizophrenia.,
Neuropsychiatric Disease and Treatment, Vol.15, 293-301, 2019.

(要約): Recently, cognitive variables such as negative and positive self-belief and thoughts have attracted much attention because they are associated with functional outcomes and quality of life (QOL). However, it is unclear how cognitive variables affect subjective and objective QOL. This study aimed to investigate the relationship of negative and positive self-belief and thoughts with subjective and objective QOL. Thirty-six people with schizophrenia participated in this study. Subjective and objective QOL were assessed with the Schizophrenia Quality of Life Scale (SQLS) and Quality of Life Scale (QLS), respectively. Neurocognitive function was assessed with the Brief Assessment of Cognition in Schizophrenia (BACS). Clinical symptoms were assessed with the Positive and Negative Syndrome Scale and Calgary Depression Scale for Schizophrenia. Side effects were assessed with the Drug-induced Extrapyramidal Symptoms Scale (DIEPSS). Negative and positive self-belief and thoughts were assessed with the Defeatist Performance Belief Scale and Automatic Thoughts Questionnaire-Revised. A generalized linear model was tested, with subjective and objective QOL as the response variable and symptoms, neurocognitive function, and cognitive variables that were significantly correlated with subjective and objective QOL as explanatory variables. In the schizophrenia group, the common objects score on the QLS was predicted by the composite BACS score, and the total QLS score was predicted by the DIEPSS score. Motivation and Energy, Psychosocial, and Symptoms and Side effects scores on the SQLS were predicted by depression and by negative automatic thought (NAT) and positive automatic thought (PAT). Our results indicated that key targets for improving objective and subjective QOL in people with schizophrenia are side effects, neurocognitive function, depression, and NAT and PAT.
(徳島大学機関リポジトリ): ● Metadata: 113356
(出版サイトへのリンク): ● Publication site (DOI): 10.2147/NDT.S190381
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 30718955; ● Summary page in Scopus @ Elsevier: 2-s2.0-85062679097

(徳島大学機関リポジトリ: 113356, DOI: 10.2147/NDT.S190381, PubMed: 30718955, Elsevier: Scopus) Makoto Kinoshita, Masahito Nakataki, Ryoma Morigaki, Satsuki Sumitani, Satoshi Goto, Ryuji Kaji and Tetsuro Ohmori :
Turning on the Left Side Electrode Changed Depressive State to Manic State in a Parkinson's Disease Patient Who Received Bilateral Subthalamic Nucleus Deep Brain Stimulation: A Case Report.,
Clinical Psychopharmacology and Neuroscience, Vol.16, No.4, 494-496, 2018.

(要約): No previous reports have described a case in which deep brain stimulation elicited an acute mood swing from a depressive to manic state simply by switching one side of the bilateral deep brain stimulation electrode on and off. The patient was a 68-year-old woman with a 10-year history of Parkinson's disease. She underwent bilateral subthalamic deep brain stimulation surgery. After undergoing surgery, the patient exhibited hyperthymia. She was scheduled for admission. On the first day of admission, it was clear that resting tremors in the right limbs had relapsed and her hyperthymia had reverted to depression. It was discovered that the left-side electrode of the deep brain stimulation device was found to be accidentally turned off. As soon as the electrode was turned on, motor impairment improved and her mood switched from depression to mania. The authors speculate that the lateral balance of stimulation plays an important role in mood regulation. The current report provides an intriguing insight into possible mechanisms of mood swing in mood disorders.
(徳島大学機関リポジトリ): ● Metadata: 114301
(出版サイトへのリンク): ● Publication site (DOI): 10.9758/cpn.2018.16.4.494
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 30466222; ● Summary page in Scopus @ Elsevier: 2-s2.0-85055838752

(徳島大学機関リポジトリ: 114301, DOI: 10.9758/cpn.2018.16.4.494, PubMed: 30466222, Elsevier: Scopus) Takeo Tominaga, Masahito Tomotake, Tomoya Takeda, Yoshinori Ueoka, Tsunehiko Tanaka, Shinya Watanabe, Naomi Kameoka, Masahito Nakataki, Shusuke Numata, Yumiko Izaki, Satsuki Sumitani, hiroko Kubo, Yasuhiro Kaneda and Tetsuro Ohmori :
Relationship between social and cognitive functions in people with schizophrenia,
Neuropsychiatric Disease and Treatment, Vol.14, 2215-2224, 2018.

(要約): The purpose of the present study was to examine clinical factors related to social function in people with schizophrenia. The participants were 55 stabilized outpatients with schizophrenia. Their mean age was 39.36 (SD =10.65) years. Social function was assessed using the Quality of Life Scale (QLS). Cognitive function was evaluated with the Measurement and Treatment Research to Improve Cognition in Schizophrenia Consensus Cognitive Battery (MCCB). Clinical symptoms were assessed using the Positive and Negative Syndrome Scale (PANSS), the Calgary Depression Scale for Schizophrenia, and the Drug-Induced Extrapyramidal Symptoms Scale. Neither the MCCB cognitive domain score nor composite score was correlated with the QLS scores. However, of the 10 MCCB subtests, the Trail Making Test Part A and the Brief Assessment of Cognition in Schizophrenia-Symbol Coding (BACS-SC) scores were positively correlated with the QLS scores. Among clinical variables, especially the PANSS negative syndrome scale score had a strong negative correlation with the QLS scores. Stepwise regression analyses showed that the PANSS negative syndrome scale score was an independent predictor of the QLS scores, and although the BACS-SC score predicted the QLS common objects and activities subscale score, the association was not so strong compared to the PANSS negative syndrome scale score. These results indicate that speed of processing evaluated by BACS-SC could predict some aspect of social function but negative symptoms have a much stronger impact on global social function in people with schizophrenia.
(徳島大学機関リポジトリ): ● Metadata: 114525
(出版サイトへのリンク): ● Publication site (DOI): 10.2147/NDT.S171207
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 30214211; ● Summary page in Scopus @ Elsevier: 2-s2.0-85057540520

(徳島大学機関リポジトリ: 114525, DOI: 10.2147/NDT.S171207, PubMed: 30214211, Elsevier: Scopus) Tomoya Takeda, Satsuki Sumitani, Sayo Hamatani, Y Yokose, M Shikata and Tetsuro Ohmori :
Prefrontal cortex activation during neuropsychological tasks might predict response to pharmacotherapy in patients with obsessive-compulsive disorder.,
Neuropsychiatric Disease and Treatment, Vol.23, No.13, 577-583, 2017.

(要約): We investigated oxyhemoglobin change in the prefrontal cortex (PFC) of patients with obsessive-compulsive disorder (OCD) who showed different responses to pharmacotherapy during neuropsychological tasks with near-infrared spectroscopy. A total of 42 patients with OCD (mean age: 35.6±9.6 years, 14 men, 28 women) and healthy control subjects (mean age: 35.4±9.7 years, 13 men, 29 women) were selected. Patients with OCD were divided into three groups (responders to selective serotonin-reuptake inhibitors (SSRIs), responders to SSRIs with antipsychotics, and nonresponders to SSRIs and SSRIs with antipsychotics) based on pharmacological response. We investigated oxyhemoglobin change in the PFC of subjects during Stroop tasks and a verbal fluency test with near-infrared spectroscopy. Responders to SSRIs showed smaller activation compared to control subjects during the Stroop incongruent task and verbal fluency test, but not during the Stroop congruent task. In contrast, responders to SSRIs with antipsychotics showed smaller activation compared to control subjects during all three tasks. Our results suggest that activation of the PFC during Stroop tasks might predict responses to pharmacotherapy of patients with OCD.
(徳島大学機関リポジトリ): ● Metadata: 114061
(出版サイトへのリンク): ● Publication site (DOI): 10.2147/NDT.S127752
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 28260905; ● Search Scopus @ Elsevier (PMID): 28260905; ● Search Scopus @ Elsevier (DOI): 10.2147/NDT.S127752

(徳島大学機関リポジトリ: 114061, DOI: 10.2147/NDT.S127752, PubMed: 28260905) Hiroko Kubo, Masahito Nakataki, Satsuki Sumitani, Junichi Iga, Shusuke Numata, Naomi Kameoka, Shinya Watanabe, Hidehiro Umehara, Makoto Kinoshita, Masatoshi Inoshita, Mai Tamaru, Masashi Ohta, Chiaki Nakayama-Yamauchi, Yasuhiro Funakoshi, Masafumi Harada and Tetsuro Ohmori :
1H-magnetic resonance spectroscopy study of glutamate-related abnormality in bipolar disorder.,
Journal of Affective Disorders, Vol.208, 139-144, 2017.

(要約): Previous studies of patients with bipolar disorder (BD) using magnetic resonance spectroscopy (MRS) have shown neurophysiological abnormalities related to the glutamate (Glu)-glutamine (Gln) cycle, membrane turnover, and neuronal integrity, although the results were neither consistent nor conclusive. Recently it has been reported the Gln/Glu ratio is the most useful index, quantifying neuronal-glial interactions and the balance of glutamatergic metabolites In this MRS study, we elucidated the abnormalities of metabolites in a larger sample of patients with BD with a high-field MRI system. Sixty-two subjects (31 patients with BD and 31 healthy controls [HC]) underwent 3T proton MRS (1H-MRS) of the anterior cingulate cortex (ACC) and left basal ganglia (ltBG) using a stimulated echo acquisition mode (STEAM) sequence. After verifying the data quality, 20 patients with BD and 23 age- and gender-matched HCs were compared using repeated-measures analysis of covariance (ANCOVA). Compared to the HC group, the BD group showed increased levels of Gln, creatine (Cr), N-acetyl aspartate (NAA), choline (Cho), and an increased ratio of Gln to Glu in the ACC, and increased Gln and Cho in the ltBG. These findings remained after the participants with BD were limited to only euthymic patients. After removing the influence of lithium (Li) and sodium valproate (VPA), we observed activated glutamatergic neurotransmission in the ACC but not in the ltBG. The present findings are cross-sectional and metabolites were measured in only two regions. Our results support a wide range of metabolite changes in patients with BD involved in glutamatergic neurotransmission, membrane turnover, and neuronal integrity. Moreover, the elevation of Gln/Glu ratio suggested that hyperactivity of glutamatergic neurotransmission in the ACC is a disease marker for BD.
(徳島大学機関リポジトリ): ● Metadata: 109987
(出版サイトへのリンク): ● Publication site (DOI): 10.1016/j.jad.2016.08.046
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 27770643; ● Summary page in Scopus @ Elsevier: 2-s2.0-85008670828

(徳島大学機関リポジトリ: 109987, DOI: 10.1016/j.jad.2016.08.046, PubMed: 27770643, Elsevier: Scopus) Hidehiro Umehara, Shusuke Numata, Atsushi Tajima, Akira Nishi, Masahito Nakataki, Issei Imoto, Satsuki Sumitani and Tetsuro Ohmori :
Calcium Signaling Pathway Is Associated with the Long-Term Clinical Response to Selective Serotonin Reuptake Inhibitors (SSRI) and SSRI with Antipsychotics in Patients with Obsessive-Compulsive Disorder.,
PLoS ONE, Vol.11, No.6, e0157232., 2016.

(要約): Selective serotonin reuptake inhibitors (SSRI) are established first-line pharmacological treatments for obsessive-compulsive disorder (OCD), while antipsychotics are used as an augmentation strategy for SSRI in OCD patients who have either no response or a partial response to SSRI treatment. The goal of the present study was to identify genetic variants and pathways that are associated with the long-term clinical response of OCD patients to SSRI or SSRI with antipsychotics. We first performed a genome-wide association study of 96 OCD patients to examine genetic variants contributing to the response to SSRI or SSRI with antipsychotics. Subsequently, we conducted pathway-based analyses by using Improved Gene Set Enrichment Analysis for Genome-wide Association Study (i-GSEA4GWAS) to examine the combined effects of genetic variants on the clinical response in OCD. While we failed to detect specific genetic variants associated with clinical responses to SSRI or to SSRI with an atypical antipsychotic at genome-wide levels of significance, we identified 8 enriched pathways for the SSRI treatment response and 5 enriched pathways for the treatment response to SSRI with an antipsychotic medication. Notably, the calcium signaling pathway was identified in both treatment responses. Our results provide novel insight into the molecular mechanisms underlying the variability in clinical response to SSRI and SSRI with antipsychotics in OCD patients.
(徳島大学機関リポジトリ): ● Metadata: 110039
(出版サイトへのリンク): ● Publication site (DOI): 10.1371/journal.pone.0157232
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 27281126; ● Summary page in Scopus @ Elsevier: 2-s2.0-84975507364

(徳島大学機関リポジトリ: 110039, DOI: 10.1371/journal.pone.0157232, PubMed: 27281126, Elsevier: Scopus) Hidehiro Umehara, Shusuke Numata, Makoto Kinoshita, Shinya Watanabe, S Nakaaki, Satsuki Sumitani and Tetsuro Ohmori :
No association between BDNF Val66Met polymorphism and treatment response in obsessive-compulsive disorder in the Japanese population.,
Neuropsychiatric Disease and Treatment, Vol.12, 611-615, 2016.

(要約): Brain-derived neurotrophic factor (BDNF) is a member of the neurotrophin family, and it promotes the development and function of dopaminergic and serotonergic neurons. The Met allele of the BDNF Val66Met polymorphism is associated with a decrease in activity-dependent secretion of BDNF compared with the Val allele, and a number of studies have provided evidence for the association between this polymorphism and obsessive-compulsive disorder (OCD). The purpose of this study was to investigate whether this functional variant of the BDNF gene is associated with OCD and treatment response in patients with OCD in the Japanese population. We first performed a case-control association study between the BDNF Val66Met polymorphism and OCD (175 cases and 2,027 controls). Then, we examined an association between this polymorphism and treatment response in 96 patients with OCD. We found no significant association between the Met allele and OCD risk or between the Met allele and treatment responses to selective serotonin reuptake inhibitors or serotonin reuptake inhibitor with an atypical antipsychotic (P>0.05). Our results suggest that the BDNF Val66Met polymorphism may not be associated as a risk factor for developing OCD or with therapeutic response in patients with OCD in the Japanese population.
(徳島大学機関リポジトリ): ● Metadata: 115651
(出版サイトへのリンク): ● Publication site (DOI): 10.2147/NDT.S102100
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 27042072; ● Search Scopus @ Elsevier (PMID): 27042072; ● Search Scopus @ Elsevier (DOI): 10.2147/NDT.S102100

(徳島大学機関リポジトリ: 115651, DOI: 10.2147/NDT.S102100, PubMed: 27042072) Naomi Kameoka, Junichi Iga, Mai Tamaru, Takeo Tominaga, Hiroko Kubo, Shinya Watanabe, Satsuki Sumitani, Masahito Tomotake and Tetsuro Ohmori :
Risk factors for refeeding hypophosphatemia in Japanese inpatients with anorexia nervosa.,
The International Journal of Eating Disorders, Vol.49, No.4, 402-406, 2016.

(要約): Refeeding in patients with anorexia nervosa (AN) is associated with a risk of refeeding syndrome, which is a disruption in metabolism with a variety of features including hypophosphatemia. We evaluated the risk factors for refeeding hypophosphatemia (RH) during nutritional replenishment in Japanese patients with AN. We retrospectively examined clinical data for 99 female inpatients (mean age 30.9 ± 10.7 years; range, 9 - 56 years). RH (phosphate < 2.3 mg/dL) occurred within 4.8 ± 3.7 days of hospital admission and was still observed at 28 days after admission in 21 of the 99 cases (21.2%). Oral or intravenous phosphate was given to some patients to treat or prevent RH. Patients with RH had a significantly lower body mass index, were older, and had higher blood urea nitrogen than those without RH. Severe complications associated with RH were recorded in only one patient who showed convulsions and disturbed consciousness at Day 3 when her serum phosphate level was 1.6 mg/dL. The significant risk factors for RH that we identified were lower body mass index, older age, and higher blood urea nitrogen at admission. No significant difference in total energy intake was seen between the RH and no RH groups, suggesting that RH may not be entirely correlated with energy intake. Precisely predicting and preventing RH is difficult, even in patients with AN who are given phosphate for prophylaxis. Thus, serum phosphate levels should be monitored for more than 5 days after admission.
(キーワード): Adolescent / Adult / Anorexia Nervosa / Child / Energy Intake / Female / Hospitalization / Humans / Hypophosphatemia / Japan / Middle Aged / Refeeding Syndrome / Retrospective Studies / Risk Factors / Young Adult
(徳島大学機関リポジトリ): ● Metadata: 114060
(出版サイトへのリンク): ● Publication site (DOI): 10.1002/eat.22472
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 26446402; ● Search Scopus @ Elsevier (PMID): 26446402; ● Search Scopus @ Elsevier (DOI): 10.1002/eat.22472

(徳島大学機関リポジトリ: 114060, DOI: 10.1002/eat.22472, PubMed: 26446402) 武田知也, 住谷さつき, 濱谷沙世, 横瀬洋輔, 四方めぐみ, 大森哲郎 :
成人高機能自閉症スペクトラム障害におけるWechsler式知能検査と自閉症スペクトラム指数との関連,
精神医学, Vol.57, No.11, 919-926, 2015年.

(キーワード): ASD (autism spectrum disorder) / WAIS-Ⅲ (Wechsler Adult Intelligence Scale Ⅲ) / AQ (Autism-Spectrum Quotient)
(出版サイトへのリンク): ● Publication site (DOI): 10.11477/mf.1405205056
(文献検索サイトへのリンク): ● CiNii @ 国立情報学研究所 (CRID): 1390001277384003072; ● Search Scopus @ Elsevier (DOI): 10.11477/mf.1405205056

(DOI: 10.11477/mf.1405205056, CiNii: 1390001277384003072) Hidehiro Umehara, Shusuke Numata, Atsushi Tajima, Makoto Kinoshita, Shutaro Nakaaki, Issei Imoto, Satsuki Sumitani and Tetsuro Ohmori :
No association between the COMT Val158Met polymorphism and the long-term clinical response in obsessive-compulsive disorder in the Japanese population.,
Human Psychopharmacology, Vol.30, No.5, 372-376, 2015.

(要約): Catechol-O-methyltransferase (COMT) is an enzyme that participates in the metabolic inactivation of dopamine and norepinephrine, and the Met allele of the COMT Val158Met polymorphism is associated with lower enzymatic activity. The purpose of the present study was to investigate whether this functional variant is associated with obsessive-compulsive disorder (OCD) and the clinical responses in OCD. We first performed a case-control association study between the COMT Val158Met polymorphism and OCD (171 cases and 944 controls). Then, we examined the association between this polymorphism and the clinical responses in 91 of the OCD patients. Our study did not find a significant association between the Met allele and OCD risk or between the Met allele and clinical responses (p > 0.05). The present case-control/pharmacogenetic study did not provide clear evidence that the COMT Val158Met polymorphism is a predictor of OCD or of OCD patients' clinical responses.
(出版サイトへのリンク): ● Publication site (DOI): 10.1002/hup.2485
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 26010653; ● Summary page in Scopus @ Elsevier: 2-s2.0-84941187896

(DOI: 10.1002/hup.2485, PubMed: 26010653, Elsevier: Scopus) Mai Hosokawa, Yoshihiro Nakadoi, Yukina Watanabe, Satsuki Sumitani and Tetsuro Ohmori :
Association of autism tendency and hemodynamic changes in the prefrontal cortex during facial expression stimuli measured by multi-channel near-infrared spectroscopy.,
Psychiatry and Clinical Neurosciences, Vol.69, No.3, 145-152, 2015.

(要約): The aim of this study is to examine the hemodynamic changes induced by the cognitive process of facial expression by using multi-channel near-infrared spectroscopy in healthy subjects with varying degrees of autism tendency. Subjects were 38 volunteers, 20 men and 18 women. Autism tendency was measured by the Autism Spectrum Quotient. The hemodynamic changes in the prefrontal cortex were measured by 24-channel near-infrared spectroscopy system, while subjects were asked to judge their own emotional response to standardized pictures of eight kinds of facial expressions on a computer screen. There were significant negative correlations between Autism Spectrum Quotient scores and accuracy of fearful expression recognition as well as increases in the concentration of oxygenated hemoglobin in response to four kinds of emotional faces (fear, contempt, sadness and disgust). Our findings suggest that the greater tendency to autism that subjects have, the more difficulty they have in recognizing a fearful expression and the less hemodynamic change in the prefrontal cortex they show in response to negative facial expressions.
(出版サイトへのリンク): ● Publication site (DOI): 10.1111/pcn.12240
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 25296773; ● Summary page in Scopus @ Elsevier: 2-s2.0-84924078741

(DOI: 10.1111/pcn.12240, PubMed: 25296773, Elsevier: Scopus) 住谷さつき :
MRS(magnetic resonance spectroscopy)による児童青年期精神疾患の研究,
児童青年精神医学とその近接領域, Vol.56, No.5, 763-772, 2015年.

(文献検索サイトへのリンク): ● CiNii @ 国立情報学研究所 (CRID): 1520853833560296064

(CiNii: 1520853833560296064) Yukina Watanabe, Satsuki Sumitani, M Hosokawa and Tetsuro Ohmori :
Prefrontal activation during two Japanese Stroop tasks revealed with multi-channel near-infrared spectroscopy.,
The Journal of Medical Investigation : JMI, Vol.62, No.1-2, 51-55, 2015.

(要約): The Stroop task is sometimes used in psychiatric research to elicit prefrontal activity, which presumably reflects cognitive functioning. Although there are two Stroop tasks (Kana script and Kanji script) in Japan, it is unclear whether these tasks elicit the same hemoglobin changes. Moreover, it is unclear whether psychological conditions or characteristics influence hemoglobin changes in the Japanese Stroop task. The aim of this study was to clarify whether hemoglobin changes elicited by the two Japanese Stroop tasks accurately reflected cognitive functioning. Hemoglobin changes were measured with multi-channel near-infrared spectroscopy (NIRS) in 100 healthy Japanese participants performing two Japanese Stroop tasks. The Beck-Depression Inventory (BDI), State-Trait-Anxiety Inventory (STAI), and Maudsley Obsessive Compulsive Inventory (MOCI) were administered to participants to identify psychological conditions or personality characteristics. Compared with the Kanji task, the Kana task produced a greater Stroop effect and a larger increase in oxyhemoglobin (oxy-Hb) concentration. Moreover there were no significant correlations between oxy-Hb concentration and BDI, STAI-trait, STAI-state, or MOCI scores. Therefore we found that a participant's psychological conditions or characteristics did not influence the hemodynamic changes during either task. These data suggest the Kana Stroop task is more useful than the Kanji Stroop task for NIRS studies in psychiatric research.
(徳島大学機関リポジトリ): ● Metadata: 111246
(出版サイトへのリンク): ● Publication site (DOI): 10.2152/jmi.62.51
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 25817284; ● Summary page in Scopus @ Elsevier: 2-s2.0-84925865443

(徳島大学機関リポジトリ: 111246, DOI: 10.2152/jmi.62.51, PubMed: 25817284, Elsevier: Scopus) Yoko Morigaki, Junichi Iga, Naomi Kameoka, Satsuki Sumitani and Tetsuro Ohmori :
Psychiatric symptoms in a patient with isolated adrenocorticotropin deficiency: case report and literature review.,
General Hospital Psychiatry, Vol.36, No.4, 449e3-e5, 2014.

(要約): We report a 59-year-old man with isolated adrenocorticotropin (ACTH) deficiency. The patient presented with sudden onset of delusions and hallucinations at the age of 54, which resolved gradually without treatment. Subsequently, the patient manifested stereotypy, wandering, hypobulia, and autistic symptoms, and was treated with antipsychotics for 1 year without any improvement. He suffered from neuroleptic malignant syndrome-like symptoms at the age of 59. A thorough endocrine assessment revealed isolated ACTH deficiency. After hydrocortisone supplementation, the physical and psychiatric symptoms improved dramatically. Clinicians should consider this rare disease when diagnosing patients with refractory psychiatric symptoms and unique physical symptoms of isolated ACTH deficiency.
(キーワード): Adrenocorticotropic Hormone / Anti-Inflammatory Agents / Endocrine System Diseases / Genetic Diseases, Inborn / Humans / Hydrocortisone / Hypoglycemia / Male / Middle Aged / Neuroleptic Malignant Syndrome / Psychotic Disorders / Treatment Outcome
(出版サイトへのリンク): ● Publication site (DOI): 10.1016/j.genhosppsych.2014.02.012
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 24725972; ● Summary page in Scopus @ Elsevier: 2-s2.0-84902840361

(DOI: 10.1016/j.genhosppsych.2014.02.012, PubMed: 24725972, Elsevier: Scopus) 中土井芳弘, 渡部幸奈, M Hosokawa, 住谷さつき, 大森哲郎 :
[Multi-channel near-infrared spectroscopy shows reduced activation in the prefrontal cortex during facial expression processing in pervasive developmental disorder],
精神神經學雜誌, Vol.115, No.3, 237-244, 2013年.

(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 23991471; ● Summary page in Scopus @ Elsevier: 2-s2.0-84891690457

(PubMed: 23991471, Elsevier: Scopus) 中土井芳弘, 渡部幸奈, 細川麻衣, 住谷さつき, 大森哲郎 :
多チャンネル近赤外線スペクトロコピーが示す広汎性発達障害の表情処理過程における前頭前野の賦活反応性の低下,
精神神經學雜誌, Vol.115, No.3, 237-244, 2013年. Makoto Kinoshita, Shusuke Numata, Atsushi Tajima, S Shimodera, S Ono, A Imamura, Junichi Iga, Shinya Watanabe, Kumiko Kikuchi, Hiroko Kubo, Masahito Nakataki, Satsuki Sumitani, Issei Imoto, Y Okazaki and Tetsuro Ohmori :
DNA Methylation Signatures of Peripheral Leukocytes in Schizophrenia.,
NeuroMolecular Medicine, Vol.Mar;15, No.1, 95-101, 2013.

(要約): Schizophrenia (SCZ) is a complex psychiatric disease with a lifetime morbidity rate of 0.5-1.0 %. To date, aberrant DNA methylation in SCZ has been reported in several studies. However, no comprehensive studies using medication-free subjects with SCZ have been conducted. In addition, most of these studies have been limited to the analysis of the CpG sites in CpG islands (CGIs) in the gene promoter regions, so little is known about the DNA methylation signatures across the whole genome in SCZ. Genome-wide DNA methylation profiling (485,764 CpG sites) of peripheral leukocytes was conducted in the first set of samples (24 medication-free patients with SCZ and 23 non-psychiatric controls) using Infinium HumanMethylation450 Beadchips. Second, a monozygotic twin study was performed using three pairs of monozygotic twins that were discordant for SCZ. Finally, the data from these two independent cohorts were compared. A total of 234 differentially methylated CpG sites that were common between these two cohorts were identified. Of the 234 CpG sites, 153 sites (65.4 %) were located in the CGIs and in the regions flanking CGIs (CGI: 40.6 %; CGI shore: 13.3 %; CGI shelf: 11.5 %). Of the 95 differently methylated CpG sites in the CGIs, most of them were located in the promoter regions (promoter: 75.8 %; gene body: 14.7 %; 3'-UTR: 2.1 %). Aberrant DNA methylation in SCZ was identified at numerous loci across the whole genome in peripheral leukocytes using two independent sets of samples. These findings support the notion that altered DNA methylation could be involved in the pathophysiology of SCZ.
(キーワード): 3' Untranslated Regions / Adult / Antipsychotic Agents / Cohort Studies / CpG Islands / DNA Methylation / DNA, Intergenic / Diseases in Twins / Female / Humans / Japan / Leukocytes / Male / Promoter Regions, Genetic / Schizophrenia / Twins, Monozygotic / Young Adult
(徳島大学機関リポジトリ): ● Metadata: 106144
(出版サイトへのリンク): ● Publication site (DOI): 10.1007/s12017-012-8198-6
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 22961555; ● Summary page in Scopus @ Elsevier: 2-s2.0-84874752700

(徳島大学機関リポジトリ: 106144, DOI: 10.1007/s12017-012-8198-6, PubMed: 22961555, Elsevier: Scopus) Tsunehiko Tanaka, Masahito Tomotake, Yoshinori Ueoka, Yasuhiro Kaneda, Kyoko Taniguchi, Masahito Nakataki, Shusuke Numata, Shinya Tayoshi, Ken Yamauchi, Satsuki Sumitani, Takashi Ohmori, Shu-ichi Ueno and Tetsuro Ohmori :
Clinical correlates associated with cognitive dysfunction in people with schizophrenia.,
Psychiatry and Clinical Neurosciences, Vol.66, No.6, 491-498, 2012.

(出版サイトへのリンク): ● Publication site (DOI): 10.1111/j.1440-1819.2012.02390.x
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 23066766; ● Search Scopus @ Elsevier (PMID): 23066766; ● Search Scopus @ Elsevier (DOI): 10.1111/j.1440-1819.2012.02390.x

(DOI: 10.1111/j.1440-1819.2012.02390.x, PubMed: 23066766) 住谷さつき :
メンタルヘルスと栄養認知症と栄養,
四国医学雑誌, Vol.68, No.1-2, 9-12, 2012年.

(要約): Japan has rapidly been becoming an aged society. Most of people are eager to grow olderhealthily. One of the most important things for aged people is how to prevent risks for dementia.It is well known that hypertention, hyperlipemia and diabetes are risk factors for vasucular dementia.Moreover recently it comes to be clear that diabetes increase the risk not only for vasucular dementiabut also for Alzheimer's disease. Mediterranean diet is well-known to prevent Alzheimerdisease. A number of prospective epidemiologic studies have found association between nutritionand dementia. For example, n‐3fatty acid, vitamins and polyphenol may be associated with decreaseof the risk for dementia. It may also be useful to prevent metabolic syndrome before aging. It isnecessary for all to mind the relationship between diet and dementia.
(キーワード): dementia / Alzheimer disease / nutrition / Mediterranean diet / n-3 fatty acid
(徳島大学機関リポジトリ): ● Metadata: 97912
(文献検索サイトへのリンク): ● CiNii @ 国立情報学研究所 (CRID): 1050302172854624384

(徳島大学機関リポジトリ: 97912, CiNii: 1050302172854624384) Yoshihiro Nakadoi, Satsuki Sumitani, Y Watanabe, M Akiyama, Naomi Yamashita and Tetsuro Ohmori :
Multi-channel near-infrared spectroscopy reveals reduced activation in the prefrontal cortex during the facial expression processing in patients with pervasive developmental disorders,
Psychiatry and Clinical Neurosciences, Vol.66, No.1, 26-33, 2012.

(要約): The purpose of the present study was to investigate whether individuals with pervasive developmental disorders (PDD) show differential activation during an emotional activation task compared with age- and sex-matched controls, by measuring changes in the concentration of oxygenated (oxyHb) and deoxygenated (deoxyHb) hemoglobin, using near-infrared spectroscopy (NIRS). Fourteen patients with PDD and 14 age- and sex-matched healthy controls participated in the study. The relative changes of concentrations of oxyHb and deoxyHb were measured on NIRS during an implicit processing task of fearful expression using Japanese standard faces. PDD patients had significantly reduced oxyHb changes in the prefrontal cortex (PFC) compared to healthy controls. PFC dysfunction may exist in PDD.
(キーワード): Adult / Brain Mapping / Case-Control Studies / Child / Child Development Disorders, Pervasive / Facial Expression / Fear / Female / Humans / Male / Mental Processes / Prefrontal Cortex / Spectroscopy, Near-Infrared
(出版サイトへのリンク): ● Publication site (DOI): 10.1111/j.1440-1819.2011.02290.x
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 22250607; ● Search Scopus @ Elsevier (PMID): 22250607; ● Search Scopus @ Elsevier (DOI): 10.1111/j.1440-1819.2011.02290.x

(DOI: 10.1111/j.1440-1819.2011.02290.x, PubMed: 22250607) 木下誠, 中瀧理仁, 住谷さつき, 大森哲郎 :
両側視床下核深部脳刺激術を施行され左側電極Onによってうつ状態から躁状態に転じたパーキンソン病の一例,
精神神經學雜誌, Vol.114, No.4, 468, 2012年. 住谷さつき :
自閉症スペクトラムと青年成人期精神障害の接点自閉症スペクトラムと強迫性障害,
児童青年精神医学とその近接領域, Vol.53, No.4, 496-500, 2012年. 住谷さつき :
精神神経疾患領域におけるMR spectroscopy,
画像診断, Vol.32, No.6, 500-506, 2012年. Yoshinori Ueoka, Masahito Tomotake, Tsunehiko Tanaka, Yasuhiro Kaneda, Kyoko Taniguchi, Masahito Nakataki, Shusuke Numata, Shinya Tayoshi, Ken Yamauchi, Satsuki Sumitani, Takashi Ohmori, Shu-ichi Ueno and Tetsuro Ohmori :
Quality of life and cognitive dysfunction in people with schizophrenia,
Progress in Neuro-Psychopharmacology & Biological Psychiatry, Vol.35, No.1, 53-59, 2011.

(要約): The main purpose of the present study was to examine the relationship between quality of life (QOL) and cognitive dysfunction in schizophrenia. Subjects were 61 stabilized outpatients. Quality of life and cognitive function were assessed using the Quality of Life Scale (QLS) and the Brief Assessment of Cognition in Schizophrenia (BACS), respectively. Clinical symptoms were evaluated with the Positive and Negative Syndrome Scale (PANSS) and the Calgary Depression Scale for Schizophrenia (CDSS). The BACS composite score and the BACS Verbal memory score were positively correlated with the QLS total score and two subscales. The BACS Attention and speed of information processing score had positive correlation with the QLS total and all the subscales scores. The PANSS Positive and Negative syndrome scores also had significant correlations with the QLS total score and all of the subscales. In addition, the CDSS score was negatively correlated with the QLS total score and some of the subscales. Stepwise regression analysis showed that the BACS Attention and speed of information processing score was an independent predictor of the QLS total score but it was less associated with the QLS than the PANSS Negative syndrome score and the CDSS score. The results suggest that negative and depressive symptoms are important factors on patients' QOL and also support the view that cognitive performance provides a determinant of QOL in patients with schizophrenia.
(キーワード): Adult / Cognition Disorders / Female / Humans / Male / Middle Aged / Neuropsychological Tests / Predictive Value of Tests / Psychiatric Status Rating Scales / Quality of Life / Questionnaires / Retrospective Studies / Schizophrenia / Young Adult
(出版サイトへのリンク): ● Publication site (DOI): 10.1016/j.pnpbp.2010.08.018
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 20804809; ● Summary page in Scopus @ Elsevier: 2-s2.0-78650960902

(DOI: 10.1016/j.pnpbp.2010.08.018, PubMed: 20804809, Elsevier: Scopus) Shinya Tayoshi, Masahito Nakataki, Satsuki Sumitani, Kyoko Taniguchi, Sumiko Tayoshi, Shusuke Numata, Junichi Iga, Shu-ichi Ueno, Masafumi Harada and Tetsuro Ohmori :
GABA concentration in schizophrenia patients and the effects of antipsychotic medication: a proton magnetic resonance spectroscopy study.,
Schizophrenia Research, Vol.117, No.1, 83-91, 2010.

(要約): Gamma-amino butyric acid (GABA) is thought to play a role in the pathophysiology of schizophrenia. High magnetic field proton magnetic resonance spectroscopy ((1)H-MRS) provides a reliable measurement of GABA in specific regions of the brain. This study measured GABA concentration in the anterior cingulate cortex (ACC) and in the left basal ganglia (ltBG) in 38 patients with chronic schizophrenia and 29 healthy control subjects. There was no significant difference in GABA concentration between the schizophrenia patients and the healthy controls in either the ACC (1.36+/-0.45 mmol/l in schizophrenia patients and 1.52+/-0.54 mmol/l in control subjects) or the ltBG (1.13+/-0.26 mmol/l in schizophrenia patients and 1.18+/-0.20 mmol/l in control subjects). Among the right handed schizophrenia patients, the GABA concentration in the ltBG was significantly higher in patients taking typical antipsychotics (1.25+/-0.24 mmol/l) than in those taking atypical antipsychotics (1.03+/-0.24 mmol/l, p=0.026). In the ACC, the GABA concentration was negatively correlated with the dose of the antipsychotics (rs=-0.347, p=0.035). In the ltBG, the GABA concentration was positively correlated with the dose of the anticholinergics (rs=0.403, p=0.015). To the best of our knowledge, this is the first study to have directly measured GABA concentrations in schizophrenia patients using (1)H-MRS. Our results suggest that there are no differences in GABA concentrations in the ACC or the ltBG of schizophrenia patients compared to healthy controls. Antipsychotic medication may cause changes in GABA concentration, and atypical and typical antipsychotics may have differing effects. It is possible that medication effects conceal inherent differences in GABA concentrations between schizophrenia patients and healthy controls.
(キーワード): Adult / Antipsychotic Agents / 脳 (brain) / Chronic Disease / Female / Humans / Magnetic Resonance Spectroscopy / Male / Protons / 統合失調症 (schizophrenia) / gamma-Aminobutyric Acid
(出版サイトへのリンク): ● Publication site (DOI): 10.1016/j.schres.2009.11.011
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 20022731; ● Search Scopus @ Elsevier (PMID): 20022731; ● Search Scopus @ Elsevier (DOI): 10.1016/j.schres.2009.11.011

(DOI: 10.1016/j.schres.2009.11.011, PubMed: 20022731) Shusuke Numata, Junichi Iga, Masahito Nakataki, Shinya Tayoshi, Kyoko Taniguchi, Satsuki Sumitani, Masahito Tomotake, Toshihito Tanahashi, Mitsuo Itakura, Yoko Kamegaya, Masahiko Tsutsumi, Akira Sano, Takashi Asada, Hiroshi Kunugi, Shu-ichi Ueno and Tetsuro Ohmori :
Gene expression and association analyses of the phosphodiesterase 4B (PDE4B) gene in major depressive disorder in the Japanese population.,
American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics, Vol.150B, No.4, 527-534, 2009.

(要約): The phosphodiesterase 4B (PDE4B) interacts with disrupted-in-schizophrenia 1 (DISC1), which is a known genetic risk factor for schizophrenia, bipolar disorder and major depressive disorder (MDD). PDE4B is also important in the regulation of cAMP signaling, a second messenger implicated in learning, memory, and mood. In this study, we determined mRNA expression levels of the PDE4B gene in the peripheral blood leukocytes of patients with MDD and control subjects (n = 33, each). Next we performed two-stage case-controlled association analyses (first set; case = 174, controls = 348; second set; case = 481, controls = 812) in the Japanese population to determine if the PDE4B gene is implicated in MDD. In the leukocytes, a significantly higher expression of the PDE4B mRNA was observed in the drug-naïve MDD patients compared with control subjects (P < 0.0001) and the expression of the MDD patients significantly decreased after antidepressant treatment (P = 0.030). In the association analysis, we observed significant allelic associations of four SNPs (the most significant, rs472952; P = 0.002) and a significant haplotypic association (permutation P = 0.019) between the PDE4B gene and MDD in the first-set samples. However, we could not confirm these significant associations in the following independent second-set of samples. Our results suggest that the PDE4B gene itself does not link to MDD but the elevated mRNA levels of PDE4B might be implicated in the pathophysiology of MDD.
(キーワード): Adult / Aged / Alleles / Case-Control Studies / Cyclic Nucleotide Phosphodiesterases, Type 4 / Depressive Disorder, Major / Female / Gene Expression / Gene Frequency / Genetic Predisposition to Disease / Genotype / Haplotypes / Humans / Japan / Male / Middle Aged / RNA, Messenger
(出版サイトへのリンク): ● Publication site (DOI): 10.1002/ajmg.b.30852
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 18785206; ● Search Scopus @ Elsevier (PMID): 18785206; ● Search Scopus @ Elsevier (DOI): 10.1002/ajmg.b.30852

(DOI: 10.1002/ajmg.b.30852, PubMed: 18785206) Shin'Ya Tayoshi, Satsuki Sumitani, Kyoko Taniguchi, Sumiko Shibuya-Tayoshi, Shusuke Numata, Jun-ichi Iga, Masahito Nakataki, Shu-ichi Ueno, Masafumi Harada and Tetsuro Ohmori :
Metabolite changes and gender differences in schizophrenia using 3-Tesla proton magnetic resonance spectroscopy (1H-MRS).,
Schizophrenia Research, Vol.108, No.1-3, 69-77, 2008.

(要約): A change in the glutamatergic system is thought to play an important role in the pathophysiology of schizophrenia. The aim of this study was to investigate the changes in metabolites, including glutamate (Glu), in the anterior cingulate cortex (ACC) and the left basal ganglia (ltBG) of patients with chronic schizophrenia using proton magnetic resonance spectroscopy ((1)H-MRS). In addition, since gender differences in this illness were known, we examined the effects of gender on these metabolites. The (1)H-MRS was performed on the ACC and ltBG of 30 patients with schizophrenia and 25 healthy individuals who acted as the control group. The levels of Glu, glutamine (Gln), creatine plus phosphocreatine (Cre), myo-inositol (mI), N-acetylaspartate (NAA), and choline-containing compounds (Cho) were measured. Two-way analysis of variance revealed that the illness significantly affected the levels of Glu and mI in the ACC; both metabolites were lower in the patients with schizophrenia as compared to the control subjects. The results also revealed that gender significantly affected the level of Gln in the ACC and the levels of Cre and NAA in the ltBG; the level of Gln in the ACC were higher in male subjects versus female subjects, whereas Cre and NAA levels in the ltBG were lower in male subjects as compared to female subjects. These results confirmed a change in the glutamatergic system and suggested an involvement of mI in the pathophysiology of schizophrenia.
(キーワード): Adult / Analysis of Variance / Aspartic Acid / Basal Ganglia / Choline / Creatine / Female / Glutamic Acid / Gyrus Cinguli / Humans / Image Processing, Computer-Assisted / Inositol / Magnetic Resonance Spectroscopy / Male / Middle Aged / Protons / 統合失調症 (schizophrenia) / Sex Characteristics / Young Adult
(出版サイトへのリンク): ● Publication site (DOI): 10.1016/j.schres.2008.11.014
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 19097753; ● Search Scopus @ Elsevier (PMID): 19097753; ● Search Scopus @ Elsevier (DOI): 10.1016/j.schres.2008.11.014

(DOI: 10.1016/j.schres.2008.11.014, PubMed: 19097753) Ken Yamauchi, Hirofumi Aki, Masahito Tomotake, Junichi Iga, Shusuke Numata, Ikuyo Motoki, Yumiko Izaki, Shinya Tayoshi, Sawako Kinouchi, Satsuki Sumitani, Sumiko Tayoshi, Yumiko Takikawa, Yasuhiro Kaneda, Takahide Taniguchi, Yasuhito Ishimoto, Shu-ichi Ueno and Tetsuro Ohmori :
Predictors of subjective and objective quality of life in outpatients with schizophrenia.,
Psychiatry and Clinical Neurosciences, Vol.62, No.4, 404-411, 2008.

(要約): AIM: In recent years, greater attention has been given to quality of life (QOL) in schizophrenia and several studies reported that negative and depressive symptoms and cognitive dysfunction are related to patient QOL. But because a variety of QOL measures have been used in the previous studies, there seems to be no unanimous predictors for subjective and objective QOL. The purpose of the present study was to elucidate the relationship between clinical variables and subjective and objective QOL in outpatients with schizophrenia, using schizophrenia disease-specific QOL measures. Particular attention was paid to cognitive function as a predictor of QOL. METHODS: Schizophrenia symptoms of the Positive and Negative Syndrome Scale (PANSS) were divided into five factors: positive factor, negative factor, cognitive factor, emotional discomfort, and hostility. The study sample consisted of 84 schizophrenia outpatients. Subjective and objective QOL were assessed with Schizophrenia Quality of Life Scale (SQLS) and the Quality of Life Scale (QLS), respectively. RESULTS: Subjective QOL correlated significantly with emotional discomfort, positive factor, negative factor, extrapyramidal symptoms and cognitive factor, while objective QOL correlated with negative factor, cognitive factor, emotional discomfort, extrapyramidal symptoms, and dose of antipsychotics. Total score and three of four subscales in the QLS correlated significantly with cognitive factor, while cognitive factor had a significant correlation with only one of three scales of SQLS. Stepwise regression showed that subjective QOL was significantly predicted by emotional discomfort and extrapyramidal symptoms, while negative factor was the most important predictor of objective QOL. CONCLUSION: Cognitive dysfunction had a greater influence on objective QOL than subjective QOL. Treating depressive and negative symptoms and extrapyramidal symptoms might contribute to enhanced subjective and objective QOL.
(キーワード): Adult / Affective Symptoms / Ambulatory Care / Antipsychotic Agents / Cognition Disorders / Dose-Response Relationship, Drug / Dyskinesia, Drug-Induced / Female / Humans / Male / Middle Aged / Motivation / Psychiatric Status Rating Scales / 生活の質 (quality of life) / 統合失調症 (schizophrenia) / Schizophrenic Psychology / Social Adjustment
(出版サイトへのリンク): ● Publication site (DOI): 10.1111/j.1440-1819.2008.01818.x
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 18778437; ● Search Scopus @ Elsevier (PMID): 18778437; ● Search Scopus @ Elsevier (DOI): 10.1111/j.1440-1819.2008.01818.x

(DOI: 10.1111/j.1440-1819.2008.01818.x, PubMed: 18778437) Shusuke Numata, Shu-ichi Ueno, Junichi Iga, Hongwei Song, Masahito Nakataki, Shinya Tayoshi, Satsuki Sumitani, Masahito Tomotake, Mitsuo Itakura, Akira Sano and Tetsuro Ohmori :
Positive association of the PDE4B (phosphodiesterase 4B) gene with schizophrenia in the Japanese population.,
Journal of Psychiatric Research, Vol.43, No.1, 7-12, 2008.

(要約): The phosphodiesterase 4B (PDE4B) gene is located at 1p31, a susceptibility region for schizophrenia (SZ). Moreover, PDE4B interacts with DISC1, which is a known genetic risk factor for SZ. Recently, it was reported that the PDE4B gene is associated with SZ in Caucasian and African American populations. In this study, case-controlled association analyses were performed in the Japanese population to determine if the PDE4B gene is implicated in SZ. Thirteen single nucleotide polymorphisms (SNPs) were analyzed in 444 schizophrenic patients and 452 control subjects. Three SNPs (rs2180335, rs910694 and rs472952) were significantly associated with SZ after applying multiple test correction (p=0.039, 0.004 and 0.028). In addition, a significant association was found between specific haplotypes (rs2180335 and rs910694) and SZ (permutation p=0.001). Our result suggests that variations at the PDE4B locus may play a significant role in the etiology of SZ in the Japanese population.
(キーワード): Asian Continental Ancestry Group / Case-Control Studies / Catechol O-Methyltransferase / Chromosome Mapping / Chromosomes, Human, Pair 1 / Control Groups / Cyclic Nucleotide Phosphodiesterases, Type 4 / Female / Gene Frequency / Genetic Markers / Genetic Predisposition to Disease / Genotype / Haplotypes / Humans / Linkage (Genetics) / Linkage Disequilibrium / Male / Middle Aged / Polymorphism, Single Nucleotide / Risk Factors / 統合失調症 (schizophrenia)
(出版サイトへのリンク): ● Publication site (DOI): 10.1016/j.jpsychires.2008.01.013
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 18329668; ● Search Scopus @ Elsevier (PMID): 18329668; ● Search Scopus @ Elsevier (DOI): 10.1016/j.jpsychires.2008.01.013

(DOI: 10.1016/j.jpsychires.2008.01.013, PubMed: 18329668) Sawako Kinouchi, Junichi Iga, Shu-ichi Ueno, Ken Yamauchi, Shusuke Numata, Hongwei Song, Satsuki Sumitani, Sumiko Shibuya-Tayoshi, Mari Haku, Toshiyuki Yasui, Minoru Irahara, Kyoko Morita, Kazuhito Rokutan and Tetsuro Ohmori :
FKBP5, SERT and COMT mRNA expressions in the peripheral leukocytes during menstruation cycle in healthy reproductive females.,
Neuroscience Letters, Vol.434, No.1, 124-128, 2008.

(要約): There have been several evidences that the mRNA expressions in the peripheral leukocytes may indicate not only physical but also psychological states. The purpose of this study is whether the mRNA expressional changes in the leukocytes are related to the mental states across the menstrual cycle in reproductive healthy female subjects. Thirty-eight female subjects (22.4+/-1.4 year-old) were participated in this study at three menstruation cycle periods (menstrual, follicular and luteal phase). The FKBP5 (FK506-binding protein gene), SERT (serotonin transporter gene) and COMT (catechol-o-methyltransferase gene) mRNA expressions in the leukocytes were determined with hormonal data. The psychological changes were assessed with self-rating hospital anxiety and depression scale (HADS). Only one thirds of subjects (n=12) had regular menstrual cycles during the experiment. So we analyzed the data from these 12 subjects. The anxiety score of each subject was changed across the menstrual cycle (Friedman test: P<0.05). The FKBP5 mRNA expression was significantly lower in the follicular phase than in the other phases but no changes were seen in either SERT or COMT mRNA expressions among the phases. In conclusion, there are differences of HADS anxiety score and FKBP5 mRNA expression in the leukocytes across the menstrual cycle but there is no correlation between anxiety scores and FKBP5 mRNA.
(キーワード): Adult / Anxiety / Anxiety Disorders / Biological Markers / Catechol O-Methyltransferase / Catecholamines / Depression / Depressive Disorder / 女性 (female) / Follicular Phase / Humans / Leukocytes / Luteal Phase / Menstrual Cycle / Premenstrual Syndrome / RNA, Messenger / Reference Values / Reproduction / Serotonin / Serotonin Plasma Membrane Transport Proteins / Tacrolimus Binding Proteins
(出版サイトへのリンク): ● Publication site (DOI): 10.1016/j.neulet.2008.01.039
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 18291582; ● Summary page in Scopus @ Elsevier: 2-s2.0-40649127657

(DOI: 10.1016/j.neulet.2008.01.039, PubMed: 18291582, Elsevier: Scopus) Hongwei Song, Shu-ichi Ueno, Shusuke Numata, Junichi Iga, Sumiko Tayoshi, Masahito Nakataki, Shin'Ya Tayoshi, Ken Yamauchi, Satsuki Sumitani, Tomohito Tomotake, Tomohito Tada, Toshihito Tanahashi, Mitsuo Itakura and Tetsuro Ohmori :
Association between PNPO and schizophrenia in the Japanese population,
Schizophrenia Research, Vol.97, No.1-3, 264-270, 2007.

(要約): Accumulating evidence suggests that both homocysteine metabolism and monoaminergic neurotransmitter systems are important in schizophrenia pathology. We hypothesized that the gene PNPO (pyridoxine 5'-phosphatase oxidase gene) might be a candidate for susceptibility to schizophrenia because PNPO encodes pyridoxamine 5'-phosphate oxidase (EC 1.4.3.5), a rate-limiting enzyme in pyridoxal 5'-phosphate (PLP, vitamin B(6)) synthesis. PLP is a metabolically-active form of vitamin B(6) and thus, is required as a co-factor for enzymes involved in both homocysteine metabolism and synthesis of neurotransmitters such as catecholamine. We examined 8 single nucleotide polymorphisms (SNPs) in PNPO and its 5'-flanking regions in 359 schizophrenia patients and 582 control subjects. Four marker regions of PNPO showed significant levels of allelic associations with schizophrenia (the highest was rs2325751, P=0.004). In addition, the haplotype case-control study revealed a significant association (permutation P<0.00001) between PNPO and schizophrenia. These findings suggest that variations in PNPO may contribute to overall genetic risk for schizophrenia in the Japanese population.
(キーワード): Adult / Aged / Alleles / Asian Continental Ancestry Group / Female / Genetic Markers / Genetic Predisposition to Disease / Genotype / Haplotypes / Humans / 日本 (Japan) / Linkage Disequilibrium / Male / Middle Aged / Neurotransmitter Agents / Polymorphism, Single Nucleotide / Pyridoxaminephosphate Oxidase / Risk Factors / 統合失調症 (schizophrenia)
(出版サイトへのリンク): ● Publication site (DOI): 10.1016/j.schres.2007.08.004
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 17851041; ● Search Scopus @ Elsevier (PMID): 17851041; ● Search Scopus @ Elsevier (DOI): 10.1016/j.schres.2007.08.004

(DOI: 10.1016/j.schres.2007.08.004, PubMed: 17851041) 住谷さつき, 上野修一, 石元康仁, 谷口隆英, 友竹正人, 元木郁代, 山内健, 大森哲郎 :
強迫性障害の薬物応答性と臨床特徴について,
精神神經學雜誌, Vol.108, No.12, 1282-1292, 2006年.

(キーワード): OCD / 選択的セロトニン再取り込み阻害薬 / SSRI / 非定型抗精神病薬 / obsessive-compulsive disorder / pharmacological response / clinical feature / selective serotonin reuptake inhibitor / atypical antipsychotic
(文献検索サイトへのリンク): ● CiNii @ 国立情報学研究所 (CRID): 1521699230021528192; ● Summary page in Scopus @ Elsevier: 2-s2.0-34047257329

(CiNii: 1521699230021528192, Elsevier: Scopus) Masahito Tomotake, Yasuhiro Kaneda, Junichi Iga, Sawako Kinouchi, Sumiko Tayoshi, Ikuyo Motoki, Satsuki Sumitani, Ken Yamauchi, Takahide Taniguchi, Yasuhito Ishimoto, Shu-ichi Ueno and Tetsuro Ohmori :
Subjective and objective measures of quality of life have different predictors for people with schizophrenia.,
Psychological Reports, Vol.99, No.2, 477-487, 2006.

(要約): This study investigated the relationship between subjective and objective quality of life and assessed predictors in people with schizophrenia. The study population consisted of 99 stabilized outpatients with schizophrenia (DSM-IV) who had been regularly receiving outpatient treatment at the Department of Psychiatry, The Tokushima University Hospital. Subjective and objective quality of life were estimated using the Schizophrenia Quality of Life Scale and the Quality of Life Scale, respectively. Psychiatric symptoms were also measured with the Brief Psychiatric Rating Scale and the Calgary Depression Scale for Schizophrenia. Scores on the Schizophrenia Quality of Life Scale Motivation and Energy scales significantly correlated with the Quality of Life Scale total scores -.40 (p <.001), and with the scores on Interpersonal Relations subscale -.42 (p <.001), Instrumental Role subscale -.28 (p = .005), Intrapsychic Foundations subscale -.39 (p<.001), and Common Objects and Activities subscale -.25 (p =.014). The Schizophrenia Quality of Life Scale Psychosocial scale significantly correlated with only the Quality of Life Scale total score -.20 (p =.05), and there was no significant correlation between the scores on the Schizophrenia Quality of Life Scale Symptoms and Side-effects scales and the Quality of Life Scale. Stepwise regression analyses showed that the Calgary Depression Scale for Schizophrenia score was the most important predictor of each scale of the Schizophrenia Quality of Life Scale, and the Brief Psychiatric Rating Scale Negative Symptoms score was the most important predictor of the Quality of Life Scale total score and each subscale. These results suggest that subjective and objective quality of life have different predictors and should be considered as separate and complementary outcome variables.
(キーワード): Adult / Ambulatory Care / Brief Psychiatric Rating Scale / Cross-Sectional Studies / Depressive Disorder / Female / Humans / Japan / Male / Middle Aged / Quality of Life / Schizophrenia / Schizophrenic Psychology
(出版サイトへのリンク): ● Publication site (DOI): 10.2466/pr0.99.2.477-487
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 17153817; ● Search Scopus @ Elsevier (PMID): 17153817; ● Search Scopus @ Elsevier (DOI): 10.2466/pr0.99.2.477-487

(DOI: 10.2466/pr0.99.2.477-487, PubMed: 17153817) Shusuke Numata, Shu-ichi Ueno, Junichi Iga, Ken Yamauchi, Song Hongwei, Koji Ohta, Sawako Kinouchi, Sumiko Shibuya-Tayoshi, Shin'ya Tayoshi, Michitaka Aono, Naomi Kameoka, Satsuki Sumitani, Masahito Tomotake, Yasuhiro Kaneda, Takahide Taniguchi, Yasuhito Ishimoto and Tetsuro Ohmori :
Brain-derived neurotrophic factor (BDNF) Val66Met polymorphism in schizophrenia is associated with age at onset and symptoms.,
Neuroscience Letters, Vol.401, No.1-2, 1-5, 2006.

(要約): Brain-derived neurotrophic factor (BDNF) is a neurotrophic factor that promotes several functions of neurons and modulates neurotransmissions. It has been reported that there are alterations of BDNF levels in schizophrenic brains and that BDNF gene expressional changes would be responsible for the etiology of schizophrenia. Recent studies have shown that a variation of BDNF gene (Val66Met polymorphism) affects the function of neurons, and is associated with several neurological and psychiatrical disorders. We investigated the relationship between BDNF Val66Met polymorphism and the onset age as well as levels of clinical symptoms in 159 of chronic schizophrenia in-patients diagnosed by DSM-IV. The mean onset ages were 27.5+/-9.5 for BDNF Val/Val, 25.5+/-7.4 for BDNF Val/Met and 22.9+/-6.0 for BDNF Met/Met and this polymorphism was significantly associated with age at onset (P=0.023). The mean Brief Psychiatric Rating Scale scores (BPRS) were significantly different among those three groups (P=0.003). No significant differences were demonstrated comparing the BDNF genotype distributions of positive and negative family history (P=0.21). Our investigation indicates that the BDNF gene Val66Met polymorphism is related to the onset age of schizophrenia and the levels of clinical symptoms that remain after long-term antipsychotic treatment.
(キーワード): Adult / Age of Onset / Aged / Amino Acid Substitution / Antipsychotic Agents / 脳 (brain) / Brain Chemistry / Brain-Derived Neurotrophic Factor / DNA Mutational Analysis / Drug Resistance / Female / Gene Frequency / Genetic Predisposition to Disease / Genetic Testing / Genotype / Humans / Male / Methionine / Middle Aged / Polymorphism, Genetic / 統合失調症 (schizophrenia) / Valine
(出版サイトへのリンク): ● Publication site (DOI): 10.1016/j.neulet.2006.02.054
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 16533563; ● Search Scopus @ Elsevier (PMID): 16533563; ● Search Scopus @ Elsevier (DOI): 10.1016/j.neulet.2006.02.054

(DOI: 10.1016/j.neulet.2006.02.054, PubMed: 16533563) Satsuki Sumitani, Tsunehiko Tanaka, Shinya Tayoshi, Koshi Ota, naomi Kameoka, Shu-ichi Ueno and Tetsuro Ohmori :
Activation of the prefrontal cortex during the Wisconsin Card Sorting Test as measured by multichannel near-infrared spectroscopy.,
Neuropsychobiology, Vol.53, No.2, 70-76, 2006.

(要約): The Wisconsin Card Sorting Test (WCST) is a neuropsychological test to evaluate the function of the prefrontal cortex (PFC). However, inconsistent results have been reported concerning whether this task activates the PFC symmetrically or asymmetrically. To investigate the brain activation in the PFC during the WCST, we examined blood oxygenation changes of healthy subjects by using multichannel near-infrared spectroscopy (NIRS). Subjects were 32 healthy volunteers, 18 males and 14 females. The WCST was administered using a computerized version, and the hemodynamic changes of the PFC during the WCST were measured by a 24-channel NIRS system. A bilateral increase in oxygenated hemoglobin (oxyHb) was observed in the PFC in 20 subjects during the WCST. However, 5 subjects showed predominant activation on the left side and 3 subjects one on the right side. No oxyHb change was observed in 4 subjects, although they had good performances in the WCST. These results directly confirmed that the PFC was activated during the WCST in vivo by using the optical technique and suggested that the distribution of the activation in the PFC is different among healthy individuals.
(キーワード): Adult / Brain Mapping / Cerebrovascular Circulation / Decision Making / Female / Functional Laterality / Humans / Male / Middle Aged / Neuropsychological Tests / Oxyhemoglobins / Pattern Recognition, Visual / Prefrontal Cortex / Psychomotor Performance / Reference Values / Reproducibility of Results / Spectroscopy, Near-Infrared
(出版サイトへのリンク): ● Publication site (DOI): 10.1159/000091722
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 16511337; ● Search Scopus @ Elsevier (PMID): 16511337; ● Search Scopus @ Elsevier (DOI): 10.1159/000091722

(DOI: 10.1159/000091722, PubMed: 16511337) Satsuki Sumitani, Tsunehiko Tanaka, Shin'Ya Tayoshi, Koshi Ota, Naomi Kameoka, Mizuki Morimune, Sumiko Shibuya-Tayoshi, Sawako Kinouchi, Shu-ichi Ueno and Tetsuro Ohmori :
Hemodynamic changes in the prefrontal cortex during mental works as measured by multi channel near-infrared spectroscopy (NIRS),
The Journal of Medical Investigation : JMI, Vol.52, No.Supplement, 302-303, 2005.

(要約): To investigate the brain activation in the prefrontal cortex (PFC) during mental works, we examined blood oxygenation changes of healthy subjects by using multi channel near infrared spectropcopy (NIRS). It was directly confirmed that the PFC was activated during mental tasks in vivo and it was suggested that distribution of the activation in the PFC is different among healthy individuals.
(キーワード): near infrared spectropcopy (NIRS) / prefrontal cortex (PFC) / the wisconsin card sorting test (WCST) / the verbal fluency test (VFT) / the uchida-kraepelin test (UKT)
(徳島大学機関リポジトリ): ● Metadata: 111588
(出版サイトへのリンク): ● Publication site (DOI): 10.2152/jmi.52.302
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 16366522; ● Search Scopus @ Elsevier (PMID): 16366522; ● Search Scopus @ Elsevier (DOI): 10.2152/jmi.52.302

(徳島大学機関リポジトリ: 111588, DOI: 10.2152/jmi.52.302, PubMed: 16366522) 住谷さつき, 中平仁, 瀬川裕美子, 大森哲郎 :
長期にわたる摂食障害が躁状態発症とともに消失した一症例,
Bipolar Disorder, Vol.2, 41-47, 2004年. 山内健, 武久美奈子, 津野麻美, 住谷さつき, 永峰勲, 大森哲郎 :
発作後もうろう状態時に多飲水し水中毒の症状を呈したてんかん患者の1症例,
臨床精神医学, Vol.32, No.3, 315-319, 2003年.

(キーワード): Epilepsy / Water Intoxication / Polydipsia / Postictal Twilight State
(文献検索サイトへのリンク): ● CiNii @ 国立情報学研究所 (CRID): 1521980704707071104

(CiNii: 1521980704707071104) 沼田周助, 住谷さつき, 永峰勲, 大森哲郎 :
Paroxetineが著効した幼児期発症の社会恐怖の一症例,
精神医学, Vol.44, No.12, 1321-1324, 2002年.

(キーワード): Social phobia / Paroxetine / Early onset
(文献検索サイトへのリンク): ● CiNii @ 国立情報学研究所 (CRID): 1522262180157499904

(CiNii: 1522262180157499904) 住谷さつき, 中瀧理仁, 石元康仁, 大森哲郎 :
fluvoxamineとrisperidoneの併用が効果的であったOCDの3症例,
強迫性障害の研究 3, 69-74, 2002年. 谷口隆英, 兼田康宏, 河上晋也, 住谷さつき, 大久保晃, 大森哲郎 :
薬原性錐体外路症状を有する症例におけるquetiapineへの切り替え効果,
臨床精神医学, Vol.31, No.3, 299-304, 2002年.

(キーワード): クエチアピン / extrapyramidal symptoms / switching / 精神分裂病 / schizophrenia
(文献検索サイトへのリンク): ● CiNii @ 国立情報学研究所 (CRID): 1523388080219130496

(CiNii: 1523388080219130496) 原田雅史, 住谷さつき, 久保均, 岡田稔子, 西谷弘, 大森哲郎 :
強迫性障害におけるproton MRSによる評価, --- 特にグルタミン酸とグルタミン代謝に対して ---,
日本磁気共鳴医学会雑誌, Vol.22, No.Suppl, 248, 2002年. 住谷さつき, 谷口隆英, 大森哲郎 :
長期にわたる過食と嘔吐がfluvoxamineにより消失した中年男性の一症例,
臨床精神医学, Vol.31, No.3, 307-312, 2002年. 住谷さつき, 石元康仁, 大森哲郎 :
Fluvoxamineとrisperidoneの併用が効果的であった分裂病性人格障害を伴うOCDの一症例,
精神科治療学, Vol.16, No.8, 841-845, 2001年. 住谷さつき, 上岡千世, 谷口隆英, 永峰勲, 大森哲郎 :
行為障害, --- 症例と考察 ---,
四国医学雑誌, Vol.56, No.5, 174-184, 2000年.

(徳島大学機関リポジトリ): ● Metadata: 110464

(徳島大学機関リポジトリ: 110464)

MISC

石澤有紀, 坂東良美, 住谷さつき, 丹黒章, 葉久真理 :
研究に関する男女共同参画・ダイバーシティの推進状況に関するアンケート調査-全国の集計結果との比較から見える徳島大学の現状-,
徳島大学人と地域共創センター紀要, Vol.31, 17-32, 2022年.

(要約): 本調査では，全国ダイバーシティネットワークの幹事機関である大阪大学と，日本学術会議科学者委員会男女共同参画分科会・同アンケート検討小分科会が共同で実施した「大学・研究機関における男女共同参画・ダイバーシティの推進状況調査」のうち「大学・研究機関における男女共同参画の推進状況に対する意見・感想」について，徳島大学回答分(男性60 件，女性21 件)のみ抽出されたデータを用いて，本学における男女共同参画・ダイバーシティ推進に関する研究者の意識調査を実施した．男女別に集計し，公開されている全国集計結果(計10，105 件)と比較検討することで，全国における本学の位置付けについて分析した．調査項目は， 1 ．男女共同参画の推進(全般) 2 ．男女共同参画の取り組み 3 ．ワークライフバランス・育児支援サービス 4 ．ダイバーシティ対応 5 ．ハラスメント防止体制 6 ．医学系の6 項目にわたる．全国と徳島での回答差，また男女間の回答差から，現在の徳島大学の研究者における男女共同参画に対する意識について考察する．
(キーワード): ダイバーシティ推進 / 男女共同参画 / 女性研究者支援
(徳島大学機関リポジトリ): ● Metadata: 116860
(文献検索サイトへのリンク): ● CiNii @ 国立情報学研究所 (CRID): 1520010707343811712

(徳島大学機関リポジトリ: 116860, CiNii: 1520010707343811712) 住谷さつき :
難治性うつ病の薬物治療,
Fulvoxamine Area Report, 11-13, 2006年. 森垣洋子, 住谷さつき, 亀岡尚美, 大森哲郎 :
ステロイド補充により精神症状が改善したACTH単独欠損症の1例,
精神神經學雜誌, Vol.115, No.6, 678, 2013年. Hidehiro Umehara, Satsuki Sumitani and Tetsuro Ohmori :
Restless legs syndrome with chest and back restlessness as the initial symptom,
Psychiatry and Clinical Neurosciences, Vol.64, No.2, 211, 2010.

(キーワード): Back / Diagnosis, Differential / Humans / Magnetic Resonance Imaging / Male / Middle Aged / Psychomotor Agitation / Restless Legs Syndrome / Thorax
(出版サイトへのリンク): ● Publication site (DOI): 10.1111/j.1440-1819.2009.02053.x
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 20447017; ● Search Scopus @ Elsevier (PMID): 20447017; ● Search Scopus @ Elsevier (DOI): 10.1111/j.1440-1819.2009.02053.x

(DOI: 10.1111/j.1440-1819.2009.02053.x, PubMed: 20447017) 住谷さつき :
不安障害に対する評価尺度の使い方,
第27回国際神経精神薬理学会(CINP)2010総会ニュースレター, 2010年.

総説・解説

住谷さつき :
【子どもの精神科薬物治療について考える】子どもの強迫症に対する薬物治療,
精神科治療学, Vol.36, No.10, 1171-1176, 2021年10月.

(キーワード): obsessive-compulsive disorder / selective serotonin reuptake inhibitor / child / adolescence / pharmacotherapy
(文献検索サイトへのリンク): ● CiNii @ 国立情報学研究所 (CRID): 1520010381331911296

(CiNii: 1520010381331911296) 住谷さつき :
【強迫についてあらためて考える】強迫症の薬物療法,
精神医学, Vol.63, No.6, 923-931, 2021年6月.

(キーワード): 強迫症 (obsessive-compulsive disorder : OCD) / 選択的セロトニン再取り込み阻害薬 (selective serotonin reuptake inhibitor : SSRI) / セロトニン (serotonin) / グルタミン酸 (glutamate) / 薬物療法 (pharmacotherapy) / キョウハクショウ (obsessive-compulsive disorder : OCD) / センタクテキセロトニンサイトリコミソガイヤク (selective serotonin reuptake inhibitor : SSRI) / グルタミンサン (glutamate) / ヤクブツリョウホウ (pharmacotherapy)
(出版サイトへのリンク): ● Publication site (DOI): 10.11477/mf.1405206385
(文献検索サイトへのリンク): ● CiNii @ 国立情報学研究所 (CRID): 1390006982830641152; ● Search Scopus @ Elsevier (DOI): 10.11477/mf.1405206385

(DOI: 10.11477/mf.1405206385, CiNii: 1390006982830641152) 住谷さつき :
神経発達症と不安症および強迫症,
臨床精神医学, Vol.48, No.10, 1173-1178, 2019年10月.

(キーワード): 自閉スペクトラム症 (Autism Spectrum Disorder) / 社交不安症 (Social Anxiety Disorder) / 強迫症 (Obsessive-Compulsive Disorder) / 併存 (comorbidity) / 成人期 (adult) / ジヘイスペクトラムショウ (Autism Spectrum Disorder) / シャコウフアンショウ (Social Anxiety Disorder) / キョウハクショウ (Obsessive-Compulsive Disorder) / ヘイソン (comorbidity) / セイジンキ (adult)
(文献検索サイトへのリンク): ● CiNii @ 国立情報学研究所 (CRID): 1521980703401345920

(CiNii: 1521980703401345920) 住谷さつき :
小児・児童の強迫症/強迫性障害の臨床,
Depression Strategy, Vol.7, No.2, 12-14, 2017年6月.

(キーワード): 子どもの強迫症/強迫性障害 (OCD) / 心理教育 / 認知行動療法 (CBT) / 薬物療法 / コドモノキョウハクショウ/キョウハクセイショウガイ (OCD) / シンリキョウイク / ニンチコウドウリョウホウ (CBT) / ヤクブツリョウホウ
(文献検索サイトへのリンク): ● CiNii @ 国立情報学研究所 (CRID): 1523951030903092480

(CiNii: 1523951030903092480) 住谷さつき :
強迫症/強迫性障害に対する抗精神病薬による増強療法,
精神科治療学, Vol.32, No.4, 449-454, 2017年4月.

(キーワード): SSRI / antipsychotics / augumentation / aripiprazole / risperidone
(文献検索サイトへのリンク): ● CiNii @ 国立情報学研究所 (CRID): 1520854805316874368

(CiNii: 1520854805316874368) 住谷さつき :
自閉症スペクトラムと強迫症/強迫性障害,
最新精神医学, Vol.22, No.3, 219-225, 2017年. 住谷さつき :
強迫性障害に対する薬物療法,
臨床精神医学, Vol.44, No.11, 1497-1503, 2015年. 住谷さつき :
精神科領域における最近のMRIの進歩:高磁場MRSの精神疾患への応用,
精神科, Vol.22, No.4, 394-400, 2013年4月.

(キーワード): proton magnetic resonance spectroscopy(proton MRS) / high-field MRS / N-acetyl aspartate(NAA) / glutamate / gamma amino butyric acid(GABA)
(文献検索サイトへのリンク): ● CiNii @ 国立情報学研究所 (CRID): 1522543655983811328

(CiNii: 1522543655983811328) 中土井芳弘, 渡部幸奈, 細川麻衣, 住谷さつき, 大森哲郎 :
発達障害の病態生理解明の最先端: 広汎性発達障害における多チャンネル近赤外線スペクトロスコピーを用いた表情処理過程,
日本生物学的精神医学会誌, Vol.24, No.4, 235-240, 2013年.

(キーワード): 広汎性発達障害(PDD) / 近赤外線スペクトロスコピー(NIRS) / 前頭前野(PFC) / 情動喚起課題
(文献検索サイトへのリンク): ● CiNii @ 国立情報学研究所 (CRID): 1390001205412474752

(CiNii: 1390001205412474752) 住谷さつき :
強迫性障害の神経生物学的基盤,
臨床精神医学, Vol.41, No.1, 13-20, 2012年. 中瀧理仁, 久保弘子, 住谷さつき, 大森哲郎 :
MRSを用いた統合失調症研究,
精神科治療学, Vol.26, No.11, 1427-1433, 2011年. 住谷さつき, 大森哲郎 :
神経症圏障害のすべて Ⅲ各論 e.強迫性障害 3.治療学,
臨床精神医学, Vol.35, No.6, 843-848, 2006年. 伊賀淳一, 住谷さつき, 大森哲郎 :
) 統合失調症の前駆症状にパロキセチンとオランザピンの併用が有効であった一症例,
抗うつ薬の新たな治療戦略, 66-67, 2003年. 住谷さつき, 大森哲郎 :
難治性強迫性障害の治療,
こころの科学, Vol.104, 48-51, 2002年6月.

講演・発表

Hidehiro Umehara, Shusuke Numata, Shinya Watanabe, Satsuki Sumitani and Tetsuro Ohmori :
Altered Serotonin transporter mRNA expression in the peripheral leukocytes of obsessive-compulsive disorder.,
30th CINP World Congress of Neuropsychopharmacology, Seoul, Jul. 2016. Masashi Ohta, Y Funakoshi, Masafumi Harada, Junichi Iga, Hiroko Kubo, Masahito Nakataki, C Nakayama, T Nishikawa, Shusuke Numata, Tetsuro Ohmori, Satsuki Sumitani, M Tamaru and A. Uezato :
Structural and functional brain alterations in schizophrenia patients treated with D-cycloserine:a combination of VBM and resting-state functional connectivity study.,
30th CINP World Congress of Neuropsychopharmacology, Seoul, Jul. 2016. Tomoya Takeda, Satsuki Sumitani, Masahito Nakataki, Sayo Hamatani, Y Yokose, M Shikata and Tetsuro Ohmori :
Relationship between WAIS- and AQ in Japanese ASD patients with average intelligence quotient.,
31st International Congress of Psychology, Tokyo, Jul. 2016. Hidehiro Umehara, Shusuke Numata, Atsushi Tajima, A NISHI, Issei Imoto, Satsuki Sumitani and Tetsuro Ohmori :
A genome-wide association study of the long-term clinical response to SSRI or SSRI with antipsychotics in obsessive-compulsive disorder in the Japanese population,
Neuroscience, Chicago, Oct. 2015. Hidehiro Umehara, Shusuke Numata, Atsushi Tajima, Makoto Kinoshita, Nakaaki Shutaro, Issei Imoto, Satsuki Sumitani and Tetsuro Ohmori :
Association between the COMT Val158Met polymorphism and the clinical response to SSRI or SSRI with antipsychotics in obsessive-compulsive disorder.,
Neuroscience, Washington DC, Nov. 2014. Satsuki Sumitani and Tetsuro Ohmori :
Clinical features and response to pharmacotherapy in patients with obsessive-compulsive disorder.,
11th World Congress of Biological Psychiatry, Kyoto, Jun. 2013. Masahito Nakataki, Satsuki Sumitani, Hiroko Kubo, Shusuke Numata, Junichi Iga, Shinya Watanabe, Makoto Kinoshita, Masafumi Harada and Tetsuro Ohmori :
Structural brain asymmetry in obsessive-compulsive disorder.,
11th world congress of biological psychiatry, Kyoto, Jun. 2013. Masahito Nakataki, Satsuki Sumitani, Hiroko Kubo, Masafumi Harada and Tetsuro Ohmori :
Caudate asymmetry in obesessive compulsive disorder: A voxel based morphometry study,
28th CINP World Congress of Neuropsychopharmacology, Stockholm, Jun. 2012. Hiroko Kubo, Sumiko Tayoshi, Satsuki Sumitani and Tetsuro Ohmori :
Effects of Lithium on the Cognitive Function in healthy Volunteers,
2nd Congress of Asian College of Neuropsychopharmacology, Seoul, Sep. 2011. Masahito Nakataki, Shinya Tayoshi, Hiroko Kubo, Junichi Iga, Shinya Watanabe, Satsuki Sumitani, Masafumi Harada and Tetsuro Ohmori :
Amino acid neurotransmission in schizophrenia patients and the effects of antipsychotic medication: A proton magnetic resonance spectroscopy study,
10th World Conbress of Biological Psychiatry, Prague, Czech Republic, Jun. 2011. Satsuki Sumitani, 渡部幸奈, 秋山麻衣 and Tetsuro Ohmori :
Relationship between he level of difficulty of task and hemodynamic change measured by NIRS,
10th World Conbress of Biological Psychiatry, Prague, Czech Republic, Jun. 2011. Satsuki Sumitani and Tetsuro Ohmori :
Clinical features in patients with obsessive-compulsive disorder with different pharmacological response,
XXVII CINP CONGRESS 2010 WORLD CONGRESS, Hong Kong, Jun. 2010. Yoshinori Ueoka, Masahito Tomotake, Tsunehiko Tanaka, Yasuhiro Kaneda, Masahito Nakataki, Satsuki Sumitani, Shu-ichi Ueno and Tetsuro Ohmori :
Quality of Life and Cognitive Dysfunction in People with Schizophrenia,
The 1st Meeting of the Asian College of Neuropsychopharmacology, Nov. 2009. Masahito Tomotake, Yoshinori Ueoka, Tsunehiko Tanaka, Yasuhiro Kaneda, Ken Yamauchi, Kyoko Taniguchi, Yumiko Takikawa, Masahito Nakataki, Shusuke Numata, Shinya Tayoshi, Satsuki Sumitani, Yumiko Izaki, Takashi Ohmori, Shu-ichi Ueno and Tetsuro Ohmori :
Subjective quality of life and cognitive function in people with schizophrenia,
XIV World Congress of Psychiatry, Sep. 2008. Yoshinori Ueoka, Masahito Tomotake, Tsunehiko Tanaka, Yasuhiro Kaneda, Ken Yamauchi, Kyoko Taniguchi, Yumiko Takikawa, Masahito Nakataki, Shusuke Numata, Shinya Tayoshi, Satsuki Sumitani, Yumiko Izaki, Takashi Ohmori, Shu-ichi Ueno and Tetsuro Ohmori :
Predictors of objective quality of life in people with schizophrenia,
XIV World Congress of Psychiatry, Sep. 2008. Shinya Tayoshi, Sumiko Tayoshi, Satsuki Sumitani, Masafumi Harada, Shu-ichi Ueno and Tetsuro Ohmori :
Maintenance modified electroconvulsive therapy for an elderly patient with recurrent catatonia,
Higashihiroshima, Oct. 2006. Shinya Tayoshi, Sumiko Tayoshi, Satsuki Sumitani, Masafumi Harada, Shu-ichi Ueno and Tetsuro Ohmori :
Six cases of elderly patients with psychotic feature refractory to drug therapy but response to ECT,
Higashihiroshima, Oct. 2006. Shinya Tayoshi, Satsuki Sumitani, Sumiko Tayoshi, Shu-ichi Ueno, Masafumi Harada and Tetsuro Ohmori :
Acute administration of benzodiazepine did not change the level of GABA in 3T 1H-Magnetic resonance spectroscopy,
Chicago, Jul. 2006. Satsuki Sumitani, Mami Matsushita, Kayoko Wada, Masahito Tomotake, Shu-ichi Ueno, Taketoshi Yamashita, Shinichi Matsumoto, Ryuji Kaji and Tetsuro Ohmori :
Comparison of the temperament between obsessive-compulsive disorder and idiopathic dystonia,
CINP, Paris, Jun. 2004. 石澤有紀, 三成美保, 坂東良美, 住谷さつき, 丹黒章, 葉久真理 :
研究に関する男女共同参画・ダイバーシティの推進状況に関するアンケート調査 -全国の集計結果との比較から見える徳島大学の現状-,
第262回徳島医学会学術集会(令和2年度冬期), 2021年3月. 住谷さつき :
ワークショップ精神神経誌に掲載される論文の書き方「症例報告の投稿経験」,
第116回日本精神神経学会総会, 2020年9月. 中瀧理仁, 久保弘子, 住谷さつき, 沼田周助, 亀岡尚美, 渡部真也, 梅原英裕, 大田将史, 原田雅史, 大森哲郎 :
双極性障害患者におけるアミノ酸系神経伝達物質の異常,
第15回日本うつ病学会総会, 2018年7月. 大田将史, 中瀧理仁, 住谷さつき, 沼田周助, 伊賀淳一, 久保弘子, 田丸麻衣, 中山千明, 船越康宏, 上里彰仁, 原田雅史, 西川徹, 大森哲郎 :
D-サイクロセリンにより治療された統合失調症患者における脳構造的および機能的結合性変化 VBMと安静時fMRIによるコンビネーション研究.,
第13回日本統合失調症学会, 2018年3月. 武田知也, 中瀧理仁, 大田将史, 濱谷沙世, 松浦可苗, 吉田玲於奈, 亀岡尚美, 富永武男, 坂本新介, 梅原英裕, 木下誠, 久保弘子, 渡部真也, 沼田周助, 住谷さつき, 大森哲郎 :
統合失調症患者の否定的・肯定的自動思考と臨床要因との関連,
第13回統合失調症学会, 2018年3月. Hidehiro Umehara, Shusuke Numata, Shinya Watanabe, Satsuki Sumitani and Tetsuro Ohmori :
Altered Serotonin transporter mRNA expression in the peripheral leukocytes of obsessive-compulsive disorder,
第47回日本神経精神薬理学会・第39回日本生物学的精神医学会合同年会, Sep. 2017. 久保弘子, 中瀧理仁, 住谷さつき, 原田雅史, 大森哲郎 :
MRSを用いた気分安定薬服用中の双極性障害患者におけるグルタミン酸神経伝達の異常,
第26回日本臨床精神神経薬理学会, 2016年11月. 梅原英裕, 沼田周助, 田嶋敦, 井本逸勢, 住谷さつき, 大森哲郎 :
GWASによる強迫性障害の薬物反応性関連パスウエイの同定,
第26回日本臨床精神神経薬理学会, 2016年11月. 住谷さつき, 大森哲郎 :
気分の変動と摂食障害の症状が連動した双極性障害の一例,
第13回日本うつ病学会総会, 2016年8月. 大田将史, 中瀧理仁, 田丸麻衣, 久保弘子, 中山千明, 船越康宏, 上里彰仁, 沼田周助, 伊賀淳一, 住谷さつき, 原田雅史, 西川徹, 大森哲郎 :
D-サイクロセリンにより治療された統合失調症患者における内側前頭前皮質の機能的統合安静時fMRI研究,
第46回日本神経精神薬理学会, 2016年7月. 江戸宏彰, 渡部真也, 住谷さつき, 大森哲郎 :
一過性に精神病症状が出現した強迫性障害の一例,
第56回中国・四国精神神経学会, 2015年11月. 武田知也, 住谷さつき, 濱谷沙世, 横瀬洋輔, 四方めぐみ, 大森哲郎 :
Stroopおよび言語流暢性検査を用いた強迫性障害患者の脳血流変化の検討,
第37回日本生物学的精神医学会, 2015年9月. 梅原英裕, 沼田周助, 住谷さつき, 大森哲郎 :
強迫性障害の治療反応性とセロトニントランスポータ遺伝子多型との関連,
第37回日本生物学的精神医学会, 2015年9月. 住谷さつき, 武田知也, 濱谷沙世, 横瀬洋輔, 四方めぐみ, 大森哲郎 :
成人高機能自閉スペクトラム症におけるWechsler式知能検査と自閉症スペクトラム指数との乖離,
第35回日本精神科診断学会, 2015年8月. 梅原英裕, 沼田周助, 住谷さつき, 大森哲郎 :
HTR2A -1438G/A多型と強迫性障害の治療反応性との遺伝関連研究,
第7回日本不安症学会学術大会, 2015年2月. 梅原英裕, 沼田周助, 田嶋敦, 井本逸勢, 住谷さつき, 大森哲郎 :
ゲノムワイド関連解析による強迫性障害の薬物反応性予測遺伝子多型の検討,
第7回日本不安症学会学術大会, 2015年2月. 久保弘子, 中瀧理仁, 住谷さつき, 大森哲郎 :
MRSによる双極性障害におけるリチウムの作用の検討.,
第24回日本臨床精神神経薬理学会, 2014年11月. 梅原英裕, 沼田周助, 田嶋敦, 木下誠, 仲秋秀太郎, 井本逸勢, 住谷さつき, 大森哲郎 :
BDNF Val66Met多型と強迫性障害;メタ解析ならびに治療反応性,
第24回日本臨床精神神経薬理学会, 2014年11月. 住谷さつき, 亀岡尚美, 亀沖彩乃, 細尾綾子, 大森哲郎 :
施設入所中高齢者の介護負担に影響する要因の検討,
第34回日本精神科診断学会, 2014年11月. 藤田美香, 木下誠, 住谷さつき, 大森哲郎 :
初診時にけいれん発作を生じてんかんとの鑑別に苦慮した統合失調症の1例.,
第55回中国・四国精神神経学会., 2014年10月. 枝川令音, 井下真利, 住谷さつき, 大森哲郎 :
躁状態や妄想にオランザピンが著効したステロイド精神病の一例,
第55回中国・四国精神神経学会., 2014年10月. 梅原英裕, 沼田周助, 田嶋敦, 木下誠, 仲秋秀太郎, 井本逸勢, 住谷さつき, 大森哲郎 :
COMT Val158Met多型と強迫性障害の遺伝子関連ならびにメタ解析研究,
第36回日本生物学的精神医学会, 2014年9月. 武田知也, 上岡義典, 住谷さつき, 大森哲郎 :
発達障害が疑われ最終診断が広汎性発達障害者と他の精神疾患者のWAIS-IIIの比較,
日本心理学会第78回大会, 2014年9月. 中村公哉, 住谷さつき, 大森哲郎 :
大うつ病性障害に伴う頭痛に対しアリピラゾールが奏功した一例,
第37回日本心身医学会中国・四国地方会, 2013年11月. 中内緑, 前川美波, 曽我彩美, 佐藤光代, 高松典通, 住谷さつき, 谷口浩一郎, 立花直子 :
日中の眠気を主訴としPSG+MSLTを行ったが，結果の解釈が困難となった強迫神経症の一症例,
第5回日本臨床睡眠医学会, 2013年8月. 亀岡尚美, 住谷さつき, 亀沖彩乃, 細尾綾子, 大森哲郎 :
施設入所中高齢者における時計描写テストの特徴,
第32回日本精神科診断学会, 2012年11月. 住谷さつき, 亀岡尚美, 細尾綾子, 亀沖彩乃, 大森哲郎 :
Zarit介護負担尺度を用いた高齢者の介護負担度に影響を与える要因の検討,
第32回日本精神科診断学会, 2012年11月. 森垣洋子, 住谷さつき, 亀岡尚美, 大森哲郎 :
ステロイド補充により精神症状が改善したACTH単独欠損症の一例,
第53回中国・四国精神神経学会, 2012年11月. 住谷さつき, 渡部幸奈, 細川麻衣, 大森哲郎 :
仮名と漢字における認知処理過程の差異-NIRSを用いた検討-,
第12回精神疾患と認知機能研究会, 2012年11月. 木下誠, 中瀧理仁, 住谷さつき, 大森哲郎 :
片側電極のOn-Offによって躁状態とうつ状態を呈した両側STN-DBSを施行されたパーキンソン病の一例,
第34回日本生物学的精神医学会, 2012年9月. 住谷さつき :
認知症と栄養(シンポジウムメンタルヘルスと栄養),
第244回徳島医学会学術集会, 2012年2月. 亀岡尚美, 住谷さつき, 大森哲郎 :
徳島大学病院精神科神経科における外来初診時診断の動向,
第31回日本精神科診断学会, 2011年11月. 木下誠, 中瀧理仁, 住谷さつき, 大森哲郎 :
両側視床下核深部脳刺激術を施行され左側電極Onによってうつ状態から躁状態に転じたパーキンソン病の一例,
第52回中国・四国精神神経学会, 2011年11月. 住谷さつき :
自閉症スペクトラムと強迫性障害(シンポジウム自閉症スペクトラムと青年成人期精神障害の接点),
第52回日本児童青年精神医学会総会, 2011年11月. 亀岡尚美, 住谷さつき, 大森哲郎 :
徳島大学病院精神科神経科における児童思春期初診患者の動向,
第52回日本児童青年精神医学会総会, 2011年11月. 中瀧理仁, 久保弘子, 伊賀淳一, 渡部真也, 住谷さつき, 原田雅史, 大森哲郎 :
統合失調症患者におけるアミノ酸神経伝達が抗精神病薬から受ける影響 1H-MRS(proton magnetic resonance spectroscopy)を用いた検討,
第21回日本臨床精神神経薬理学会・第41回日本神経精神薬理学会合同年会, 2011年10月. 住谷さつき, 田吉伸哉, 中瀧理仁, 大森哲郎 :
高磁場MRSを用いた非侵襲的脳内代謝物質測定による統合失調症アミノ酸仮説の検討,
第7回統合失調症研究会, 2011年2月. 秋山麻衣, 住谷さつき, 大森哲郎 :
選択性緘黙の15歳女児との心理療法過程-筆談によるコミュニケーションを通して-,
第51回日本児童青年精神医学会, 2010年10月. 住谷さつき, 上西優介, 渡邊周平, 渡部幸奈, 秋山麻衣, 大森哲郎 :
近赤外線スペクトロスコピーを用いた課題の難易度と前頭葉血流変化の関連,
第32回日本生物学的精神医学会, 2010年10月. Yoshinori Ueoka, Masahito Tomotake, Tsunehiko Tanaka, Yasuhiro Kaneda, Masahito Nakataki, Shusuke Numata, Shinya Tayoshi, Satsuki Sumitani, Takashi Ohmori, Shu-ichi Ueno and Tetsuro Ohmori :
Subjective Quality of Life and Cognitive Function in Outpatients with Schizophrenia,
第5回日本統合失調症学会, Mar. 2010. Yoshinori Ueoka, Masahito Tomotake, Tsunehiko Tanaka, Yasuhiro Kaneda, Masahito Nakataki, Satsuki Sumitani, Shu-ichi Ueno and Tetsuro Ohmori :
Quality of Life and Cognitive Dysfunction in People with Schizophrenia,
第19回日本臨床精神神経薬理学会・第39回日本神経精神薬理学会合同年会, Nov. 2009. 中土井芳弘, 長尾智子, 井上麻由, 沼田周助, 住谷さつき, 友竹正人, 大森哲郎 :
抗精神病薬が有効であった高次脳機能障害を合併した神経性無食欲症の1例,
第50回中国四国精神神経学会, 2009年11月. Masahito Tomotake, Yoshinori Ueoka, Tsunehiko Tanaka, Yasuhiro Kaneda, Ken Yamauchi, Kyoko Taniguchi, Takikawa Yumiko, Masahito Nakataki, Shusuke Numata, Shinya Tayoshi, Satsuki Sumitani, Yumiko Izaki, Takashi Ohmori, Shu-ichi Ueno and Tetsuro Ohmori :
Quality of life and cognitive function in outpatients with schizophrenia,
第18回日本臨床精神神経薬理学会・第38回日本神経精神薬理学会合同年会, Oct. 2008. Yoshinori Ueoka, Masahito Tomotake, Tsunehiko Tanaka, Yasuhiro Kaneda, Masahito Nakataki, Shusuke Numata, Shinya Tayoshi, Satsuki Sumitani, Yumiko Izaki, Takashi Ohmori, Shu-ichi Ueno and Tetsuro Ohmori :
Relationship between cognitive function and clinical factors in people with schizophrenia,
第18回日本臨床精神神経薬理学会・第38回日本神経精神薬理学会合同年会, Oct. 2008. 梅原英裕, 住谷さつき, 大森哲郎 :
胸腹部の不快感を主訴としたレストレスレッグズ症候群の一症例,
第49回日本心身医学会総会, 2008年6月. Shusuke Numata, Shu-ichi Ueno, Junichi Iga, Ken Yamauchi, Hongwei Song, Koji Ohta, Sawako Kinouchi, Sumiko Tayoshi, Shinya Tayoshi, Michitaka Aono, Naomi Kameoka, Satsuki Sumitani, Masahito Tomotake, Yasuhiro Kaneda, Takahide Taniguchi, Yasuhito Ishimoto and Tetsuro Ohmori :
Brain-derived neurotrophic factor (BDNF) Val66Met polymorphism in schizophrenia is associated with age of onset,
The 2nd Annual Meeting of Japanse Society of Schizophrenia Research, Mar. 2007. Syusuke Numata, Shu-ichi Ueno, Junichi Iga, Ken Yamauchi, Hongwei So, Koshi Ohta, Sawako Kinouchi, Sumiko Shibuya-Tayoshi, Shinya Tayoshi, Michitaka Aono, Naomi Kameoka, Satsuki Sumitani, Masahito Tomotake and et al :
Brain-derived neurotrophic factor (BDNF) Val66Met polymorphism in schizophrenia is associated with age at onset,
第2回日本統合失調症学会, Mar. 2007. 住谷さつき, 上野修一, 石元康仁, 谷口隆英, 友竹正人, 他 :
OCDのSSRIと非定型抗精神病薬に対する応答性と臨床特徴について,
第8回OCD研究会, 2006年11月. 住谷さつき, 原田雅史, 久保均, 田吉伸哉, 田吉純子, 木内佐和子, 上野修一, 大森哲郎 :
3T proton MRSを用いたOCDの脳内代謝物の検討,
2006年9月. Shusuke Numata, Shu-ichi Ueno, Junichi Iga, Ken Yamauchi, Hongwei Song, Sawako Kinouchi, Sumiko Tayoshi, Shinya Tayoshi, Satsuki Sumitani and Tetsuro Ohmori :
BDNFVal66Met polymorphism in schizophrenia is associated with age of onset and symptoms.,
The 28th Annual Meeting of Japanese Society of Biological Psychiatry, Sep. 2006. 住谷さつき, 原田雅史, 久保均, 大森哲郎 :
薬物応答性の異なるOCDのProton MRSによる検討,
第26回日本生物学的精神医学会, 2004年7月. 住谷さつき, 大森哲郎 :
OCDの薬物治療応答性と臨床特徴について,
第100回日本精神神経学会, 2004年5月. 住谷さつき, 松下真美, 和田香代子, 友竹正人, 他 :
TCIを用いたOCDと特発性ジストニアのパーソナリティーの比較,
第99回日本精神神経学会, 2003年5月. 住谷さつき, 沼田周助, 谷口隆英, 大森哲郎 :
Quetiapineにより多飲が改善した統合失調症の1症例,
第14回西日本精神神経学会, 2002年11月. 住谷さつき, 松下真美, 和田香代子, 友竹正人, 他 :
TCIを用いたOCDとジストニアのパーソナリティーの比較,
第4回OCD研究会, 2002年11月. 沼田周助, 住谷さつき, 永峰勲, 大森哲郎 :
ParoParoxetineが著効した会食恐怖を主症状とする社会恐怖の1症例,
第43回中国・四国精神神経学会, 2001年11月.

研究会・報告書: 武田知也, 中瀧理仁, 大田将史, 濱谷沙世, 松浦可苗, 吉田玲於奈, 亀岡尚美, 富永武男, 坂本新介, 梅原英裕, 木下誠, 久保弘子, 渡部真也, 沼田周助, 住谷さつき, 大森哲郎 :
統合失調症患者における神経認知機能と否定的・肯定的認知の関連.,
第4回CEPD会, 2018年3月. 武田知也, 住谷さつき, 濱谷沙世, 横瀬洋輔, 四方めぐみ, 大森哲郎 :
成人高機能自閉症スペクトラム障害におけるWechsler式知能検査と自閉症スペクトラム指数との関連,
第15回精神疾患と認知機能研究会, 2015年11月. 住谷さつき :
治療抵抗性強迫性障害に対するドパミン・パーシャル・アゴニストの有用性の検討,
第11回DPA研究会, 2015年1月. 住谷さつき :
書評子どもの強迫性障害診断・治療ガイドライン,
児童青年精神医学とその近接領域, Vol.54, No.2, 213-214, 2013年. 住谷さつき :
パニック・強迫・対人恐怖の診断と治療,
めんたる・へるす, Vol.61, 52-64, 2012年. 住谷さつき :
認知症の診断と治療,
阿南医報, Vol.169, 7, 2012年. 住谷さつき :
第51回日本児童青年精神医学会印象記,
精神医学, Vol.53, No.2, 200, 2011年. 住谷さつき :
社交不安障害,
GSKホームページこころの薬箱, 2010年. 沼田周助, 中瀧理仁, 伊賀淳一, 田吉伸哉, 谷口京子, 住谷さつき, 友竹正人, 他 :
大うつ病の末梢白血球におけるPDE4B遺伝子の発現と関連研究,
第41回精神神経系薬物治療研究報告会, 2008年12月. 住谷さつき :
近赤外分光法を用いた前頭葉機能検査遂行時の脳血行動態の検討,
2006年9月. 住谷さつき, 原田雅史, 久保均, 田吉伸哉, 田吉純子, 木内佐和子, 上野修一, 大森哲郎 :
3T1H-MRSを用いた強迫性障害の脳内代謝物の検討,
強迫性障害の研究7, 15-21, 2006年. 住谷さつき, 原田雅史, 久保均, 大森哲郎 :
薬物応答性の異なるOCDのprotonMRSを用いた検討,
厚生労働省精神神経疾患研究委託費精神疾患における脳の画像解析学的研究, 2004年12月. 住谷さつき, 原田雅史, 久保均, 大森哲郎 :
薬物応答性の異なるOCDのProton MRSを用いた検討,
第6回OCD研究会, 2004年11月. 住谷さつき :
第51回日本児童青年精神医学会印象記,
精神医学, Vol.53, No.2, 200, 2011年.

特許: 研究者総覧に該当データはありませんでした。
作品: 住谷さつき :
薬物療法が役に立つ場合，役に立たない場合,
精神科臨床サービス, Vol.15, No.1, 53-58, 2015年.
補助金・競争的資金: 高磁場MRSとNIRSを中間表現型とした強迫性障害の薬物応答遺伝子の研究 (研究課題/領域番号: 26461720 )
脳内アミノ酸系に及ぼす向精神薬の影響－高磁場MRSの精神薬理学的応用－ (研究課題/領域番号: 26461719 )
認知機能と機能画像を指標とした強迫性障害の治療戦略に関する研究 (研究課題/領域番号: 23591709 )
認知機能障害とQOLに着目した統合失調症の臨床的および脳科学的研究 (研究課題/領域番号: 21591520 )
高磁場MRSと多チャンネルNIRSを用いた強迫性障害の薬物応答性予測に関する研究 (研究課題/領域番号: 20591410 )
高磁場MRSを用いた脳内アミノ酸神経伝達物質動態による気分、不安障害の解明 (研究課題/領域番号: 18591291 )
MRI装置による脳機能評価法の開発と誤差や再現性を含めた限界についての検討 (研究課題/領域番号: 15591280 )
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専門分野・研究分野: 医学 (Medicine)
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受賞: 2012年3月, 医学部優秀教育賞 (徳島大学)
2013年3月, Best Teacher of The Year 2012 (徳島大学)
2016年10月, 教養教育賞(2016前期) (徳島大学)
2021年3月, 教養教育賞(2019) (徳島大学)
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Jグローバル最終確認日: 2024/12/21 01:23
氏名（漢字）: 住谷さつき
氏名（フリガナ）: スミタニサツキ
氏名（英字）: Sumitani Satsuki
所属機関: 徳島大学助手

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researchmap最終確認日: 2024/12/22 01:38
氏名（漢字）: 住谷さつき
氏名（フリガナ）: スミタニサツキ
氏名（英字）: Sumitani Satsuki
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所属: 徳島大学
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研究者番号: 90346594

所属（現在）: 2024/4/1 : 徳島大学, キャンパスライフ健康支援センター, 教授

所属（過去の研究課題 情報に基づく）*注記: 2016/4/1 : 徳島大学, 大学院医歯薬学研究部(総合支援), 教授
2015/4/1 : 徳島大学, 特別修学支援室, 教授
2011/4/1 – 2014/4/1 : 徳島大学, ヘルスバイオサイエンス研究部, 准教授
2009/4/1 – 2011/4/1 : 徳島大学, 大学院・ヘルスバイオサイエンス研究部, 准教授
2010/4/1 : 徳島大学, 大学院・ヘルスバイオサイエンス研究部・精神医学分野, 准教授
2007/4/1 – 2008/4/1 : 徳島大学, 医学部・歯学部附属病院, 講師
2007/4/1 : 徳島大学, 医学部・歯学部付属病院, 講師
2006/4/1 : 徳島大学, 大学院ヘルスバイオサイエンス研究部, 助手
2004/4/1 : 徳島大学, 大学院・ヘルスバイオサイエンス研究部, 助手
2003/4/1 : 徳島大学, 医学部, 助手

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生物系 / 医歯薬学 / 内科系臨床医学 / 精神神経科学

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生物系 / 医歯薬学 / 内科系臨床医学 / 精神神経科学
生物系 / 医歯薬学 / 内科系臨床医学 / 放射線科学

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研究代表者

強迫性障害 / NIRS MRS SSRI / 薬物応答性 / 脳血流 / 非定型抗精神病薬 / NAA / MRS / NIRS / SSRI / 非定型抗精神病 / 認知機能 / 機能画像 / 前頭葉 / 基底核 / 前頭葉機能 / GABA / Stroop Test / グルタミン酸 / 薬物応答遺伝子 / 中間表現型 / GWAS / 強迫性障害（OCD） / ゲノムワイドジェノタイピング / 5-HTTLPR / COMT / 気分障害 / 不安障害 / OCD / glutamate / mood disorder / anxiety disorder

研究代表者以外

統合失調症 / 認知機能 / QOL / 脳画像 / 分子遺伝学 / 精神薬理学 / 脳画像解析 / グルタミン酸 / GABA / FAIR / Proton MRS / 3T MRI / Perfusion / Metabolism / Glutamate / LCmodel / LCModeol / proton MRS / fMRI / perfusion / LCModel / ICC / ICA

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