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伊勢孝之

徳島大学

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2024年4月26日更新

職名: 助教
電話: 研究者総覧に該当データはありませんでした。
電子メール: isetaka@tokushima-u.ac.jp
学歴: 研究者総覧に該当データはありませんでした。
学位: 博士
職歴・経歴: 2011/9: 徳島大学特任助教, 病院 (-2013.3.)
2013/4: 徳島大学助教, 病院 (-2014.3.)
2014/4: 徳島大学特任助教, 病院 (-2015.3.)
2015/4: 徳島大学助教, 病院 (-2018.3.)
2018/4: 徳島大学特任助教, 病院 (-2019.3.)
2019/4: 徳島大学助教, 病院

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2024年4月26日更新

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担当経験のある授業科目: 内科学第二 (学部)
循環器コース(3年) (学部)
疾病学2 (学部)
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2024年4月26日更新

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著書

伊勢孝之, 内藤紘一, 佐藤聡見, 小野慎太郎, 石井亜由美, 西川幸治, 門田宗之, 八木秀介, 佐田政隆 :
ウェアラブルデバイスとコミュニケーションアプリを用いた遠隔伴走型心リハシステムの開発,
2023年7月. 八木秀介, 伊勢孝之, 門田宗之, Tserensonom Munkhtsetseg, 石井亜由美, 西川幸治, 佐田政隆 :
冠動脈疾患の一次予防に関する身体活動指導,
2022年10月. 賀川久美子, 前田悠作, 大浦雅博, 曽我部公子, 藤野ひかる, 髙橋真美子, 丸橋朋子, 岩佐昌美, 宇高憲吾, 原田武志, 伊勢孝之, 藤井志朗, 中村信元, 三木浩和, 八木秀介, 竹内恭子, 尾崎修治, 安倍正博, 藤野ひかる :
治療後長期生存が得られた心不全合併ALアミロイドーシス症例の検討,
臨床血液, 2017年10月.

(要約): ALアミロイドーシスは，多発性骨髄腫やMGUS(monoclonal gammopathy of undetermined significance)などのモノクローナルな形質細胞が産生する免疫グロブリン軽鎖および重鎖が，アミロイド線維として組織に沈着し，臓器障害を惹起する難治性疾患である．なかでも心アミロイドーシス(以下CA)は，心不全症状が出現してからは，無治療の場合極めて予後不良であるため，その管理・治療が重要である1)．ALアミロイドーシスに対しては，自家末梢血幹細胞移植併用メルファラン大量療法(以下ASCT)の有効性が報告されているが，CAにおいては治療関連毒性が強く，その適応を慎重に検討する必要がある2, 3)．近年，多発性骨髄腫において，ボルテゾミブ(Bor)や，免疫調節薬であるサリドマイド(Thal)やレナリドミド(Len)などの新規薬を用いた治療により，治療成績が向上している．ALアミロイドーシス症例においてもこれらの新規薬の有効性が示され，CAに対しても，重篤な有害事象の発生率が低く，有効であったとの報告がある4∼6)．しかしながら，その長期の治療成績や予後については，十分な情報がない．そこで我々は，当科において治療し，長期生存が得られた心不全合併CA例について，後方視的に検討した．
(キーワード): Cardiac AL amyloidosis / Autologous hematopoietic stem cell transplantation / Long-term survival
(出版サイトへのリンク): ● Publication site (DOI): 10.11406/rinketsu.58.2197
(文献検索サイトへのリンク): ● CiNii @ 国立情報学研究所 (CRID): 1390282680011466240; ● Search Scopus @ Elsevier (DOI): 10.11406/rinketsu.58.2197

(DOI: 10.11406/rinketsu.58.2197, CiNii: 1390282680011466240) 高島啓, 伊勢孝之, 佐田政隆 :
心不全治療に魚油が効く!?-ω-3不飽和脂肪酸慢性心不全治療へ- (第4章慢性心不全の治療 1. 内服治療 ),
株式会社メディカ出版, 大阪, 2014年10月. 伊勢孝之 :
心不全 (Chapter 2 循環器疾患),
医歯薬出版株式会社, 東京, 2014年5月.

論文

N Yamaguchi, Yukina Hirata, Susumu Nishio, Tomonori Takahashi, Yoshihito Saijo, Muneyuki Kadota, Takayuki Ise, Koji Yamaguchi, Shusuke Yagi, Hirotsugu Yamada, Takeshi Soeki, Tetsuzo Wakatsuki, Masataka Sata and Kenya Kusunose :
Pulmonary Pressure-flow responses to exercise in heart failure treated with angiotensin receptor neprilysin inhibitor.,
International Journal of Cardiology, Vol.400, 131789, 2024.

(要約): The role of the angiotensin receptor neprilysin inhibitor (ARNI) in cardiac function, particularly its impact on pulmonary circulation, remains underexplored. Recent studies have described abnormal mean pulmonary artery pressure (mPAP)-cardiac output (CO) responses as having the potential to assess the disease state. The aim of this study was to assess the effects of ARNI on pulmonary circulation in heart failure. We measured echocardiographic parameters post 6-min walk (6 MW) and compared the changes with baseline and follow-up. Our hypothesis was that pulmonary pressure-flow relationship of the pulmonary circulation obtained by 6 MW stress echocardiography would be improved with treatment. We prospectively enrolled 39 heart failure patients and conducted the 6 MW test indoors. Post-6 MW echocardiography measured echocardiographic variables, and CO was derived from electric cardiometry. Individualized ARNI doses were optimized, with follow-up echocardiographic evaluations after 1 year. Left ventricular (LV) volume were significantly reduced (160.7 ± 49.6 ml vs 136.0 ± 54.3 ml, P < 0.001), and LV ejection fraction was significantly improved (37.6 ± 11.3% vs 44.9 ± 11.5%, P < 0.001). Among the 31 patients who underwent 6 MW stress echocardiographic study at baseline and 1 year later, 6 MW distance increased after treatment (380 m vs 430 m, P = 0.003). The ΔmPAP/ΔCO by 6 MW stress decreased with treatment (6.9 mmHg/L/min vs 2.8 mmHg/L/min, P = 0.002). The left atrial volume index was associated with the response group receiving ARNI treatment for pulmonary circulation. Initiation of ARNI was associated with improvement of left ventricular size and LVEF. Additionally, the 6 MW distance increased and the ΔmPAP/ΔCO was improved to within normal range with treatment.
(徳島大学機関リポジトリ): ● Metadata: 118925
(出版サイトへのリンク): ● Publication site (DOI): 10.1016/j.ijcard.2024.131789
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 38246422; ● Search Scopus @ Elsevier (PMID): 38246422; ● Search Scopus @ Elsevier (DOI): 10.1016/j.ijcard.2024.131789

(徳島大学機関リポジトリ: 118925, DOI: 10.1016/j.ijcard.2024.131789, PubMed: 38246422) Munkhtsetseg Tserensonom, Shusuke Yagi, Takayuki Ise, Yutaka Kawabata, Muneyuki Kadota, Tomoya Hara, Kenya Kusunose, Koji Yamaguchi, Hirotsugu Yamada, Takeshi Soeki, Tetsuzo Wakatsuki and Masataka Sata :
Lipoprotein (a) is a risk factor of aortic valve calcification in patients with a risk of atherosclerosis,
The Journal of Medical Investigation : JMI, Vol.70, No.3.4, 450-456, 2023.

(要約): Aortic valve calcification (AVC), which causes aortic stenosis (AS), is more common in elderly persons. Controlling for conventional risk variables did not, however, reduce the incidence of AS. Thus, residual risk factors of AS should be identified. We enrolled 513 patients who underwent coronary angiography with computed tomography because of suspicion of coronary artery disease (CAD) or ruling out of CAD before aortic valve replacement. Calcium volume was calculated with a commercially available application. Conventional and lipid-related risk factors including serum levels of Lp(a) were evaluated for all patients. Calcium volume and Lp(a) levels were significantly higher in patients who underwent aortic valve replacement than in those who did not. A single regression analysis showed that the calcium volume was positively associated with age and the Lp(a) levels and negatively associated with the estimated glomerular filtration rate. No statistical significance was observed for other risk factors, including oxidized low-density lipoprotein, omega-3 fatty acids levels. The multiple regression analysis revealed that age (P<0.001), female sex (P<0.05), Lp(a) (P<0.01), and hemoglobin A1c (P<0.01) were determinants of the calcium volume. The area under the curve in receiver operating characteristic analysis of Lp(a) for implementation of AVR was 0.65 at an Lp(a) cut-off level of 16 mg/dL. In conclusion, the serum Lp(a) level is a potent risk factor of AVC in patients with high risk of atherosclerosis. J. Med. Invest. 70 : 450-456, August, 2023.
(キーワード): Humans / Female / Aged / Aortic Valve / Lipoprotein(a) / Calcium / Aortic Valve Stenosis / Atherosclerosis / Risk Factors / Coronary Artery Disease
(出版サイトへのリンク): ● Publication site (DOI): 10.2152/jmi.70.450
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 37940531; ● Search Scopus @ Elsevier (PMID): 37940531; ● Search Scopus @ Elsevier (DOI): 10.2152/jmi.70.450

(DOI: 10.2152/jmi.70.450, PubMed: 37940531) Yuichiro Okushi, Yoshihito Saijyo, Hirotsugu Yamada, Hiroaki Toba, Robert Zheng, Hiromitsu Seno, Tomonori Takahashi, Takayuki Ise, Koji Yamaguchi, Shusuke Yagi, Takeshi Soeki, Tetsuzo Wakatsuki, Masataka Sata and Kenya Kusunose :
Effectiveness of surveillance by echocardiography for Cancer therapeutics-related cardiac dysfunction of patients with breast Cancer,
Journal of Cardiology, Vol.82, No.6, 467-472, 2023.

(要約): Cancer therapeutics-related cardiac dysfunction (CTRCD) affect the prognosis of patients with breast cancer. Echocardiographic surveillance of patients treated with anti-human epidermal growth factor receptor type 2 (HER2) antibodies has been recommended, but few reports have provided evidence on patients with breast cancer only. We aimed to evaluate the effectiveness of echocardiographic surveillance for breast cancer patients. We identified 250 patients with breast cancer who were treated with anti-HER2 antibodies from July 2007 to September 2021. We divided 48 patients with echocardiographic surveillance every 3 months into the surveillance group and 202 patients without echocardiographic surveillance into the non-surveillance group. In the surveillance group, patients with a considerable reduction in global longitudinal strain of 15 % were considered for the initiation of cardioprotective drugs. The composite outcome of CTRCD and acute heart failure was the study endpoint. The mean age was 59 ± 12 years. During the follow-up period of 15 months (12-17 months), 12 patients reached the endpoint. The surveillance group had significantly lower incidence of the composite outcome (2.1 % vs. 5.5 %, adjusted odds ratio: 0.28, 95 % confidential intervals: 0.09-0.94; p = 0.039) and higher rates of prescriptions of cardioprotective drugs than the non-surveillance group. The incidence of cardiac complications was significantly lower in the surveillance group than the non-surveillance group, which supports the effectiveness of echocardiographic surveillance in patients with breast cancer.
(出版サイトへのリンク): ● Publication site (DOI): 10.1016/j.jjcc.2023.07.002
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 37481235; ● Summary page in Scopus @ Elsevier: 2-s2.0-85166962366

(DOI: 10.1016/j.jjcc.2023.07.002, PubMed: 37481235, Elsevier: Scopus) Shusuke Yagi, Tomoya Hara, Hirotsugu Yamada, Kenya Kusunose, Takayuki Ise and Masataka Sata :
Intimal Sarcoma of the Pulmonary Artery as an Embolic Cause of Sudden Death,
Circulation Journal, Vol.87, No.7, 1036, 2023.

(徳島大学機関リポジトリ): ● Metadata: 118374
(出版サイトへのリンク): ● Publication site (DOI): 10.1253/circj.CJ-23-0029
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 37245990; ● Search Scopus @ Elsevier (PMID): 37245990; ● Search Scopus @ Elsevier (DOI): 10.1253/circj.CJ-23-0029

(徳島大学機関リポジトリ: 118374, DOI: 10.1253/circj.CJ-23-0029, PubMed: 37245990) Ryota Miyamoto, Takayuki Ise, Tomoya Yoshida and Masataka Sata :
Endomyocardial biopsy-proven fulminant lymphocytic myocarditis presenting with mid-apical ballooning,
European Heart Journal. Case Reports, Vol.7, No.3, ytad123, 2023.

(徳島大学機関リポジトリ): ● Metadata: 118932
(出版サイトへのリンク): ● Publication site (DOI): 10.1093/ehjcr/ytad123
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 37006797; ● Search Scopus @ Elsevier (PMID): 37006797; ● Search Scopus @ Elsevier (DOI): 10.1093/ehjcr/ytad123

(徳島大学機関リポジトリ: 118932, DOI: 10.1093/ehjcr/ytad123, PubMed: 37006797) Tomonori Takahashi, Kenya Kusunose, S Hayashi, Robert Zheng, Natsumi Yamaguchi, Sae Morita, Yukina Hirata, Susumu Nishio, Yoshihito Saijyo, Takayuki Ise, Koji Yamaguchi, Shusuke Yagi, Hirotsugu Yamada, Takeshi Soeki, Tetsuzo Wakatsuki and Masataka Sata :
Isoproterenol loading transesophageal echocardiography in atrial fibrillation,
The International Journal of Cardiovascular Imaging, Vol.39, No.3, 511-518, 2023.

(要約): In patients with sludge or severe spontaneous echo contrast (SEC) in the left atrial appendage (LAA), cases with isoproterenol loading transesophageal echocardiography (ISP-TEE) have been reported to identify the presence of thrombus in the LAA. This study aimed to assess the validity and hemodynamic changes of ISP-TEE in the LAA. We prospectively enrolled patients with atrial fibrillation (AF) who underwent ISP-TEE. The degree of sludge/SEC was categorized as being either absent (grade 0), mild SEC (grade 1), moderate SEC (grade 2), severe SEC or sludge (grade 3). The hemodynamic evaluation was performed by measuring LAA flow velocity, LAA tissue Doppler imaging (LAA-TDI) velocity, and pulmonary vein systolic forward flow velocity (PVS). In total, 35 patients (mean age 71 ± 7 years; 71% male) underwent ISP-TEE. Among 35 patients, 30 patients had grade 3 or 2 SEC, 5 patients had grade 1 SEC. After ISP loading, 23 patients (66% of all patients) showed improved sludge/SEC and one patient was diagnosed with thrombus in the LAA. There were 25 patients with grade 1 SEC, or no SEC (classified as Group1), 10 patients had residual sludge or grade 2 to 3 SEC (classified as Group2) after ISP administration. LAA flow, LAA-TDI, and PVS velocities were significantly higher in group 1 than in group 2 after ISP administration. There was no complication during the examination and after 24 h and 3 months. ISP infusion may be a potential tool to recognize LAA thrombus under the sludge/SEC during TEE in AF.
(キーワード): Humans / Male / Middle Aged / Aged / Female / Atrial Fibrillation / Echocardiography, Transesophageal / Isoproterenol / Sewage / Atrial Appendage / Predictive Value of Tests / Thrombosis
(徳島大学機関リポジトリ): ● Metadata: 118275
(出版サイトへのリンク): ● Publication site (DOI): 10.1007/s10554-022-02749-y
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 36357528; ● Search Scopus @ Elsevier (PMID): 36357528; ● Search Scopus @ Elsevier (DOI): 10.1007/s10554-022-02749-y

(徳島大学機関リポジトリ: 118275, DOI: 10.1007/s10554-022-02749-y, PubMed: 36357528) Yutaka Kawabata, Tetsuzo Wakatsuki, Koji Yamaguchi, Daiju Fukuda, Hiroyuki Ito, Tomomi Matsuura, Kenya Kusunose, Takayuki Ise, Shusuke Yagi, Hirotsugu Yamada, Takeshi Soeki, Y Tsuruo and Masataka Sata :
Association of Microluminal Structures Assessed by Optical Coherence Tomography With Local Inflammation in Adjacent Epicardial Adipose Tissue and Coronary Plaque Characteristics in Fresh Cadavers,
Circulation Journal, Vol.87, No.2, 329-335, 2023.

(要約): Coronary intraplaque microluminal structures (MS) are associated with plaque vulnerability, and the inward progression of vascular inflammation from the adventitia towards the media and intima has also been demonstrated. Therefore, in the present study we investigated the relationships among MS, local inflammation in adjacent epicardial adipose tissue (EAT), and coronary plaque characteristics.Methods and Results: Optical coherence tomography (OCT) revealed MS in the left anterior descending coronary artery in 10 fresh cadaveric hearts. We sampled 30 lesions and subdivided them based on the presence of MS: MS (+) group (n=19) and MS (-) group (n=11). We measured inflammatory molecule levels in the adjacent EAT and percentage lipid volume assessed by integrated backscatter intravascular ultrasound in each lesion. The expression levels of vascular endothelial growth factor B and C-C motif chemokine ligand 2 were significantly higher in the MS (+) group than in the MS (-) group (0.9±0.7 vs. 0.2±0.2 arbitrary units (AU), P=0.04 and 1.5±0.5 vs. 0.6±0.7 AU, P=0.02, respectively). Percentage lipid volume was significantly higher in the MS (+) group than in the MS (-) group (38.7±16.5 vs. 23.7±10.9%, P=0.03). Intraplaque MS observed on OCT were associated with lipid-rich plaques and local inflammation in the adjacent EAT. Collectively, these results suggest that local inflammation in the EAT is associated with coronary plaque vulnerability via MS.
(徳島大学機関リポジトリ): ● Metadata: 117602
(出版サイトへのリンク): ● Publication site (DOI): 10.1253/circj.CJ-22-0299
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 36244741; ● Search Scopus @ Elsevier (PMID): 36244741; ● Search Scopus @ Elsevier (DOI): 10.1253/circj.CJ-22-0299

(徳島大学機関リポジトリ: 117602, DOI: 10.1253/circj.CJ-22-0299, PubMed: 36244741) Tomonori Takahashi, Kenya Kusunose, Robert Zheng, Natsumi Yamaguchi, Yukina Hirata, Susumu Nishio, Yoshihito Saijyo, Takayuki Ise, Koji Yamaguchi, Shusuke Yagi, Hirotsugu Yamada, Takeshi Soeki, Tetsuzo Wakatsuki and Masataka Sata :
Association between cardiovascular risk factors and left ventricular strain distribution in patients without previous cardiovascular disease,
Journal of Echocardiography, Vol.20, No.4, 208-215, 2022.

(要約): Some cardiovascular (CV) risk factors, such as hypertension and diabetes mellitus, have been reported to reduce left ventricular (LV) longitudinal strain (LS) even in patients with preserved LV ejection fraction. We hypothesized that multiple CV risk factors might cause changes in myocardial strain. Our study aimed to assess the association between multiple CV risk factors and strain in patients without previous CV disease (CVD). We retrospectively evaluated 137 patients without CVD, who underwent echocardiography at our institution between May 2017 and February 2020. They were divided into four groups based on the number of risk factors (group 0: no risk factor, group 1: one risk factor, group 2: two risk factors, and groups 3: three or four risk factors). Risk factors were hypertension, dyslipidemia, diabetes mellitus, and chronic kidney disease. Absolute values of global LS (GLS) and relative apical LS ratio (RALSR) defined using the equation: average apical LS/(average basal LS + average mid LS) and was used as a marker of strain distribution. Out of 137 patients, group 0 had 35 patients, group 1 had 35 patients, group 2 had 32 patients, and group 3 had 35 patients. GLS was 22.4 ± 2.0%, 21.7 ± 2.1%, 21.3 ± 1.8%, 20.7 ± 2.2%, and RALSR was 0.64 ± 0.06, 0.66 ± 0.06, 0.68 ± 0.08, 0.69 ± 0.07 in groups 0-3, respectively. The one-way ANOVA detected significant differences between groups in GLS (p = 0.005) and RALSR (p = 0.037), respectively. Group 3 had a significantly lower GLS and higher RALSR than group 0 (p < 0.05). In patients without previous CVD, LS decreased especially from the basal segment as the number of cardiovascular risks increased. The segmental LS may be markers of occult LV dysfunction in patients with CV risk factors.
(キーワード): Humans / Cardiovascular Diseases / Retrospective Studies / Risk Factors / Stroke Volume / Ventricular Function, Left / Ventricular Dysfunction, Left / Heart Disease Risk Factors / Hypertension
(出版サイトへのリンク): ● Publication site (DOI): 10.1007/s12574-022-00576-7
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 35562627; ● Search Scopus @ Elsevier (PMID): 35562627; ● Search Scopus @ Elsevier (DOI): 10.1007/s12574-022-00576-7

(DOI: 10.1007/s12574-022-00576-7, PubMed: 35562627) O Bavuu, Daiju Fukuda, B Ganbaatar, Tomomi Matsuura, Takayuki Ise, Kenya Kusunose, Koji Yamaguchi, Shusuke Yagi, Hirotsugu Yamada, Takeshi Soeki, Tetsuzo Wakatsuki and Masataka Sata :
Esaxerenone, a selective mineralocorticoid receptor blocker, improves insulin sensitivity in mice consuming high-fat diet.,
European Journal of Pharmacology, 175190, 2022.

(要約): Esaxerenone is a novel, non-steroidal selective mineralocorticoid receptor (Csige et al.) blocker. MR activation plays a crucial role in the development of cardiovascular and metabolic diseases. In this study, we investigated the effects of esaxerenone on various metabolic parameters in mice. Esaxerenone (3 mg/kg/day) was orally administered to high-fat diet (HFD)-fed male C57BL/6 mice. Mice fed a normal diet (ND) served as controls. Glucose and insulin tolerance, plasma lipid levels, and transaminase levels were assessed as metabolic parameters. Macrophage accumulation in the adipose tissue was evaluated using histological analysis. 3T3-L1 adipocytes, HepG2 cells, and C2C12 myotubes were used for in vitro experiments. Gene expression and insulin signaling were examined using quantitative RT-PCR and western blotting, respectively. HFD successfully induced insulin resistance compared with that in ND. Esaxerenone ameliorated insulin resistance (P < 0.05) without altering other metabolic parameters, such as the lipid profile. Esaxerenone administration tended to decrease plasma transaminase levels compared with those in the non-treated group. In the adipose tissue, esaxerenone decreased macrophage accumulation (P < 0.05) and increased the expression levels of adiponectin and PPARγ. Aldosterone significantly decreased the expression levels of PPARγ and adiponectin in 3T3-L1 adipocytes. Furthermore, aldosterone attenuated insulin-induced Akt phosphorylation in 3T3-L1 adipocytes, HepG2 cells, and C2C12 myotubes in a dose-dependent manner (P < 0.01). These effects were ameliorated by pretreatment with esaxerenone. Esaxerenone ameliorated insulin resistance in HFD-fed mice. Reduction of inflammation and improvement in insulin signaling may underlie the beneficial effects of esaxerenone.
(徳島大学機関リポジトリ): ● Metadata: 117375
(出版サイトへのリンク): ● Publication site (DOI): 10.1016/j.ejphar.2022.175190
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 35961594; ● Search Scopus @ Elsevier (PMID): 35961594; ● Search Scopus @ Elsevier (DOI): 10.1016/j.ejphar.2022.175190

(徳島大学機関リポジトリ: 117375, DOI: 10.1016/j.ejphar.2022.175190, PubMed: 35961594) Kenya Kusunose, Hirotsugu Yamada, Y Saijo, Susumu Nishio, Yukina Hirata, Takayuki Ise, Koji Yamaguchi, Daiju Fukuda, Shusuke Yagi, Takeshi Soeki, Tetsuzo Wakatsuki and Masataka Sata :
Clinical course and decision-making in heart failure by preload stress echocardiography: a preliminary study,
ESC Heart Failure, Vol.9, No.6, 4020-4029, 2022.

(要約): Abnormal left ventricular diastolic response to preload stress can be an early marker of heart failure (HF). The aim of this study was to assess clinical course in patients with HF with preserved ejection fraction (HFpEF) who underwent preload stress echocardiography. In the subgroup analysis, we assessed the prognosis of patients with unstable signs during preload stress classified by treatment strategies. We prospectively conducted preload stress echocardiographic studies between January 2006 and December 2013 in 211 patients with HFpEF. Fifty-eight patients had abnormal diastolic reserve during preload stress (unstable impaired relaxation: unstable IR). Of 58 patients with unstable IR, 19 patients were assigned to additional therapy by increased or additional therapy and 39 patients were assigned to standard therapy. Composite outcomes were prespecified as the primary endpoint of death and hospitalization for deteriorating HF. During a median period of 6.9 years, 19 patients (33%) reached the composite outcome. Unstable group with standard therapy had significantly shorter event-free survival than stable group. Patients with uptitration of therapy had longer event-free survival than those with standard therapy group after adjustment of laboratory data (hazard ratio, 0.20, 95% confidence interval, 0.05-0.90; P = 0.036); the 10 year event-free survival in patients with and without uptitration of therapy was 93% and 51%, respectively (P = 0.023). Patients with unstable sign had significantly shorter event-free survival than patients with stable sign. After additional therapy, the prognosis of patients with unstable signs improved. This technique may impact decision-making for improving their prognosis.
(徳島大学機関リポジトリ): ● Metadata: 118008
(出版サイトへのリンク): ● Publication site (DOI): 10.1002/ehf2.14127
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 36017722; ● Search Scopus @ Elsevier (PMID): 36017722; ● Search Scopus @ Elsevier (DOI): 10.1002/ehf2.14127

(徳島大学機関リポジトリ: 118008, DOI: 10.1002/ehf2.14127, PubMed: 36017722) Koji Yamaguchi, Tetsuzo Wakatsuki, Tomomi Matsuura, Kazuhisa Matsumoto, Yutaka Kawabata, Muneyuki Kadota, Kenya Kusunose, Takayuki Ise, Shusuke Yagi, Daiju Fukuda, Hirotsugu Yamada, Takeshi Soeki and Masataka Sata :
Drug-coated balloon angioplasty for severe pulmonary vein stenosis resulting from cryoballoon ablation for atrial fibrillation,
Journal of Cardiology Cases, Vol.26, 35-38, 2022.

(徳島大学機関リポジトリ): ● Metadata: 117234
(出版サイトへのリンク): ● Publication site (DOI): 10.1016/j.jccase.2022.02.009
(文献検索サイトへのリンク): ● Summary page in Scopus @ Elsevier: 2-s2.0-85127324683

(徳島大学機関リポジトリ: 117234, DOI: 10.1016/j.jccase.2022.02.009, Elsevier: Scopus) Y Okushi, Kenya Kusunose, M Nakai, Y Sumita, Takayuki Ise, Koji Yamaguchi, Shusuke Yagi, Daiju Fukuda, Hirotsugu Yamada, Takeshi Soeki, Tetsuzo Wakatsuki and Masataka Sata :
Comparison of Direct Oral Anticoagulants for Acute Hospital Mortality in Venous Thromboembolism,
American Journal of Cardiovascular Drugs, Vol.22, No.4, 407-416, 2022.

(要約): The choice of direct oral anticoagulants (DOACs) for venous thromboembolism (VTE) is at the physician's discretion; however, it is useful to know the differences in the clinical data of DOACs to help physicians choose. We aimed to compare the mortality associated with the use of rivaroxaban, edoxaban, and apixaban in clinical practice. We identified 38,245 patients with first hospitalization for VTE from the Diagnosis Procedure Combination database in the Japanese Registry of All Cardiac and Vascular Datasets (JROAD-DPC). We classified patients into three groups by DOAC (rivaroxaban and edoxaban group, rivaroxaban and apixaban group, and edoxaban and apixaban group) and compared the in-hospital mortality and bleeding risk by propensity score (PS) matching in each group. After PS matching, patients with rivaroxaban use had significantly lower total in-hospital mortality (1.2% vs. 2.1%; odds ratio [OR] 0.55, p = 0.012) and in-hospital mortality within 21 days (0.4% vs. 1.0%; OR 0.41, p = 0.020) and 28 days (0.7% vs. 1.3%; OR 0.53, p = 0.042) than patients with apixaban use. In the subanalysis, significant differences were only observed in patients younger than 80 years of age, patients with pulmonary embolism, and patients without heart failure. There was no significant difference in in-hospital mortality in the other groups and in the rate of bleeding events among the three groups. On PS-matched analysis, there was a difference in in-hospital mortality, especially in the rivaroxaban and apixaban group. Identifying the clinical characteristics of patients associated with each DOAC, as well as prognosis, will be useful in determining treatment strategies for VTE.
(出版サイトへのリンク): ● Publication site (DOI): 10.1007/s40256-021-00514-5
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 34927214; ● Search Scopus @ Elsevier (PMID): 34927214; ● Search Scopus @ Elsevier (DOI): 10.1007/s40256-021-00514-5

(DOI: 10.1007/s40256-021-00514-5, PubMed: 34927214) Kazuhisa Matsumoto, Takeshi Tobiume, Tomomi Matsuura, Takayuki Ise, Kenya Kusunose, Koji Yamaguchi, Shusuke Yagi, Daiju Fukuda, Tetsuzo Wakatsuki, Hirotsugu Yamada, Takeshi Soeki and Masataka Sata :
Evaluation of the input site and characteristics of the antegrade fast pathway based on three-dimensional bi-atrial stimulus-ventricle mapping,
Journal of Interventional Cardiac Electrophysiology, Vol.63, No.2, 417-424, 2022.

(要約): Previous studies examined the right atrial (RA) input site of the antegrade fast pathway (AFp) (AFpI). However, the left atrial (LA) input to the atrioventricular (AV) node has not been extensively evaluated. In this study, we created three-dimensional (3-D) bi-atrial stimulus-ventricle (St-V) maps and analyzed the input site and characteristics of the AFp in both the RA and LA. Forty-four patients diagnosed with atrial fibrillation or WPW syndrome were included in this study. Three-dimensional bi-atrial St-V mapping was performed using an electroanatomical mapping system. Sites exhibiting the minimal St-V interval (MinSt-V) were defined as AFpIs and were classified into seven segments, four in the RA (F, S, M, and I) and three in the LA (M1, M2, and M3). By combining the MinSt-V in the RA and LA, the AFpIs were classified into three types: RA, LA, and bi-atrial (BA) types. The clinical and electrophysiological characteristics were compared. AFpIs were most frequently observed at site S in the RA (34%) and M2 in the LA (50%), and the BA type was the most common (57%). AFpIs in the LA were recognized in 75% of the patients. There were no clinical or electrophysiological indicators for predicting AFpI sites. Three-dimensional bi-atrial St-V maps could classify AFpIs in both the RA and LA. AFpIs in the LA were frequently recognized. There were no significant clinical or electrophysiological indicators for predicting AFpI sites, and 3-D bi-atrial St-V mapping was the only method to reveal the precise AFp input site.
(徳島大学機関リポジトリ): ● Metadata: 116382
(出版サイトへのリンク): ● Publication site (DOI): 10.1007/s10840-021-01026-7
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 34231099; ● Search Scopus @ Elsevier (PMID): 34231099; ● Search Scopus @ Elsevier (DOI): 10.1007/s10840-021-01026-7

(徳島大学機関リポジトリ: 116382, DOI: 10.1007/s10840-021-01026-7, PubMed: 34231099) Shusuke Yagi, Daiju Fukuda, Takayuki Ise, Koji Yamaguchi, Kenya Kusunose, Muneyuki Kadota, Yutaka Kawabata, Tomomi Matsuura, Tomohiro Soga, Hirotsugu Yamada, Takeshi Soeki, Tetsuzo Wakatsuki, Shinji Kawahito and Masataka Sata :
Clinical clerkship students' preferences and satisfaction regarding online lectures during the COVID-19 pandemic,
BMC Medical Education, Vol.22, No.1, 43, 2022.

(要約): The COVID-19 pandemic has caused an unprecedented disruption in medical education. Students and lecturers had to adapt to online education. The current study aimed to investigate the level of satisfaction and future preference for online lectures among clinical clerkship students and elucidated the factors that affect these outcomes. We selected a sample of 114 medical students undergoing clinical clerkship during the COVID-19 pandemic. We conducted onsite lectures before the pandemic and online lectures after the outbreak. A survey was conducted, and the sample included students and 17 lecturers. The average scores of total satisfaction and future preference related to online lectures were computed. Students' scores on total satisfaction with online lectures and their future preference were higher than those for onsite lectures. Scores on the ease of debating dimension were low and those on accessibility of lectures in online lectures were higher than those in onsite lectures. There was no difference between the two groups in the scores on the comprehensibility and ease of asking questions dimensions. Results of the multiple regression analysis revealed that accessibility determined total satisfaction, and future preference was determined by comprehensibility as well as accessibility. Contrary to students' future preferences, lecturers favored onsite lectures to online ones. Online lectures are an acceptable mode of teaching during the COVID-19 pandemic for students undergoing clinical clerkship. Online lectures are expected to become more pervasive to avoid the spread of COVID-19.
(キーワード): COVID-19 / Clinical Clerkship / Humans / Pandemics / Personal Satisfaction / SARS-CoV-2 / Students, Medical
(徳島大学機関リポジトリ): ● Metadata: 116989
(出版サイトへのリンク): ● Publication site (DOI): 10.1186/s12909-021-03096-7
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 35042505; ● Summary page in Scopus @ Elsevier: 2-s2.0-85123015852

(徳島大学機関リポジトリ: 116989, DOI: 10.1186/s12909-021-03096-7, PubMed: 35042505, Elsevier: Scopus) Nao Ishii, Kenya Kusunose, A Shono, K Matsumoto, Susumu Nishio, Natsumi Yamaguchi, Yukina Hirata, Tomomi Matsuura, Takayuki Ise, Koji Yamaguchi, Shusuke Yagi, Daiju Fukuda, Hirotsugu Yamada, Takeshi Soeki, Tetsuzo Wakatsuki and Masataka Sata :
Effects of Radiofrequency Catheter Ablation on Cardiac Reserve Using Preload Stress Echocardiography in Paroxysmal and Persistent Atrial Fibrillation,
The American Journal of Cardiology, Vol.168, 71-77, 2022.

(要約): The effects of catheter ablation on exercise tolerance and quality of life in patients with atrial fibrillation (AF) have been reported. We assessed cardiac function in more detail using the leg positive pressure (LPP) technique and found that contractile reserve is particularly important in relation to exercise tolerance and prognosis. In this study, we used the LPP technique to examine changes in contractile reserve immediately after ablation and 6 months later. We prospectively enrolled patients who underwent catheter ablation for AF at 2 institutes. We performed LPP stress echocardiography 2 to 3 days after (FU-1) and 6 months after (FU-2) ablation to examine changes in cardiac function indexes. The primary end point was improvement in contractile reserve. Ultimately, 109 patients (mean age 67.4 ± 9.6 years; 70% men) underwent 2 sessions of LPP stress echocardiography. The median CHADS-VAS score was 2 (interquartile range 13). From FU-1 to FU-2, the change in the stroke volume index after the LPP maneuver increased in patients with paroxysmal and persistent AF with low CHADS-VAS scores (both p <0.05). Regardless of AF subtype, contractile reserve at FU-2 improved in patients with low CHADS-VAS scores compared with that at FU-1. In contrast, patients with high CHADS-VAS scores had no change. In conclusion, patients with AF with a low CHADS-VAS score had improved contractile reserve after ablation, whereas patients with high scores did not show any improvement. Aggressive interventions in patients with high scores may lead to better management after catheter ablation.
(キーワード): Aged / Atrial Fibrillation / Catheter Ablation / Echocardiography, Stress / Female / Humans / Male / Middle Aged / Predictive Value of Tests / Quality of Life / Risk Assessment / Risk Factors / Treatment Outcome
(徳島大学機関リポジトリ): ● Metadata: 116987
(出版サイトへのリンク): ● Publication site (DOI): 10.1016/j.amjcard.2021.12.026
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 35063270; ● Search Scopus @ Elsevier (PMID): 35063270; ● Search Scopus @ Elsevier (DOI): 10.1016/j.amjcard.2021.12.026

(徳島大学機関リポジトリ: 116987, DOI: 10.1016/j.amjcard.2021.12.026, PubMed: 35063270) Kenya Kusunose, Miharu Arase, Robert Zheng, Yukina Hirata, Susumu Nishio, Takayuki Ise, Koji Yamaguchi, Daiju Fukuda, Shusuke Yagi, Hirotsugu Yamada, Takeshi Soeki, Tetsuzo Wakatsuki and Masataka Sata :
Clinical Utility of Overlap Time for Incomplete Relaxation to Predict Cardiac Events in Heart Failure: Incomplete relaxation in heart failure,
Journal of Cardiac Failure, Vol.27, No.11, 1222-1230, 2021.

(要約): The overlap time of transmitral flow can be a novel marker of subclinical left ventricular (LV) dysfunction for predicting adverse events in heart failure (HF). We aimed to 1) investigate the role of overlap time of E-A wave in association with clinical parameters, and 2) evaluate whether the overlap time could add prognostic information with respect to other conventional clinical prognosticators in HF. We prospectively evaluated 153 patients hospitalized with HF (mean age 68±15 years; 63% male). The primary endpoint was readmission following HF and cardiac death. During a median period of 25 months, 43 patients were either readmitted or died. Overlap time appeared to be associated with worse outcomes. After adjustment for readmission score and ratio of diastolic filling period and cardiac cycle length in a Cox proportional-hazards model, overlap time was associated with event free survival, independent of elevated left atrial pressure (LAP) based on guidelines. When overlap time was added to the model based on clinical variables and elevated LAP, the C-statistic significantly improves from 0.70 (95% CI: 0.63-0.77) to 0.77 (95% CI: 0.69-0.83, compared P=0.035). This preliminary study suggested that prolonged overlap time may have potential for predicting readmission and cardiac mortality risk assessment in HF.
(出版サイトへのリンク): ● Publication site (DOI): 10.1016/j.cardfail.2021.05.018
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 34129950; ● Search Scopus @ Elsevier (PMID): 34129950; ● Search Scopus @ Elsevier (DOI): 10.1016/j.cardfail.2021.05.018

(DOI: 10.1016/j.cardfail.2021.05.018, PubMed: 34129950) Robert Zheng, Kenya Kusunose, Y Okushi, Y Okayama, M Nakai, Y Sumita, Takayuki Ise, Koji Yamaguchi, Shusuke Yagi, Daiju Fukuda, Hirotsugu Yamada, Takeshi Soeki, Tetsuzo Wakatsuki and Masataka Sata :
Impact of cancer on short-term in-hospital mortality after primary acute myocardial infarction,
Open Heart, Vol.8, No.2, e00186, 2021.

(徳島大学機関リポジトリ): ● Metadata: 116972
(出版サイトへのリンク): ● Publication site (DOI): 10.1136/openhrt-2021-001860
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 34810277; ● Summary page in Scopus @ Elsevier: 2-s2.0-85120377378

(徳島大学機関リポジトリ: 116972, DOI: 10.1136/openhrt-2021-001860, PubMed: 34810277, Elsevier: Scopus) Kenya Kusunose, Hironori Takahashi, Susumu Nishio, Yukina Hirata, Robert Zheng, Takayuki Ise, Koji Yamaguchi, Shusuke Yagi, Daiju Fukuda, Hirotsugu Yamada, Takeshi Soeki, Tetsuzo Wakatsuki, Kenji Shimada, Yasuhisa Kanematsu, Yasushi Takagi and Masataka Sata :
Predictive value of left atrial function for latent paroxysmal atrial fibrillation as the cause of embolic stroke of undetermined source,
Journal of Cardiology, Vol.78, No.5, 355-361, 2021.

(要約): In patients with embolic stroke of undetermined source (ESUS), paroxysmal atrial fibrillation (AF) is often diagnosed, however, the risk of paroxysmal AF in ESUS has not been well described. Several studies have suggested a linkage between left atrial (LA) functional parameters and risk of AF in stroke patients. The aim of this study was to assess the role of LA functional parameters as predictors of latent paroxysmal AF in ESUS on admission. Between January 2015 and December 2019, consecutive stroke patients with suspected ESUS at admission were prospectively included in this study. They were under hospital electrocardiographic monitoring for detection of new-onset AF. Various echocardiographic parameters including left atrial strain were assessed for association with new-onset AF. We gathered 1082 consecutive patients with ischemic stroke. After exclusions, 121 patients with suspected ESUS at admission formed the study cohort. New-onset AF was detected in 46 (38%) patients during hospital electrocardiographic monitoring (median follow-up: 18 days). LA pump and reservoir strains were significantly and independently associated with new-onset AF. Receiver operating characteristic analysis for the association with new-onset AF showed that the areas under the curve (AUCs) of clinical parameters plus one of each strain (LA pump strain: AUC: 0.86±0.04 and LA reservoir strain: AUC: 0.76±0.05) models were significantly better than plus LA volume index (AUC: 0.68±0.04, compared p-values <0.05). LA strain was significantly associated with new development of AF. Patients with impaired LA function at admission should be carefully monitored to find AF.
(出版サイトへのリンク): ● Publication site (DOI): 10.1016/j.jjcc.2021.05.005
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 34119401; ● Search Scopus @ Elsevier (PMID): 34119401; ● Search Scopus @ Elsevier (DOI): 10.1016/j.jjcc.2021.05.005

(DOI: 10.1016/j.jjcc.2021.05.005, PubMed: 34119401) Kenya Kusunose, Yuichiro Okushi, Yoshihiro Okayama, Robert Zheng, Michikazu Nakai, Yoko Sumita, Takayuki Ise, Koji Yamaguchi, Shusuke Yagi, Daiju Fukuda, Hirotsugu Yamada, Takeshi Soeki, Tetsuzo Wakatsuki and Masataka Sata :
Use of Echocardiography and Heart Failure In-Hospital Mortality from Registry Data in Japan.,
Journal of Cardiovascular Development and Disease, Vol.8, No.10, 124, 2021.

(要約): Echocardiography requires a high degree of skill on the part of the examiner, and the skill may be more improved in larger volume centers. This study investigated trends and outcomes associated with the use and volume of echocardiographic exams from a real-world registry database of heart failure (HF) hospitalizations. This study was based on the Diagnosis Procedure Combination database in the Japanese Registry of All Cardiac and Vascular Datasets (JROAD-DPC). A first analysis was performed to assess the trend of echocardiographic examinations between 2012 and 2016. A secondary analysis was performed to assess whether echocardiographic use was associated with in-hospital mortality in 2015. During this period, the use of echocardiography grew at an average annual rate of 6%. Patients with echocardiography had declining rates of hospital mortality, and these trends were associated with high hospitalization costs. In the 2015 sample, a total of 52,832 echocardiograms were examined, corresponding to 65.6% of all HF hospital admissions for that year. We found that the use and volume of echocardiography exams were associated with significantly lower odds of all-cause hospital mortality in heart failure (adjusted odds ratio (OR): 0.48 for use of echocardiography and 0.78 for the third tertile; both < 0.001). The use of echocardiography was associated with decreased odds of hospital mortality in HF. The volumes of echocardiographic examinations were also associated with hospital mortality.
(徳島大学機関リポジトリ): ● Metadata: 117323
(出版サイトへのリンク): ● Publication site (DOI): 10.3390/jcdd8100124
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 34677193; ● Summary page in Scopus @ Elsevier: 2-s2.0-85116636823

(徳島大学機関リポジトリ: 117323, DOI: 10.3390/jcdd8100124, PubMed: 34677193, Elsevier: Scopus) Shusuke Yagi, T Takahashi, K Murakami, M Azuma, M Sugano, R Miyamoto, M Niki, Hirotsugu Yamada, Yutaka Kawabata, Tani Akihiro, Daiju Fukuda, Muneyuki Kadota, Takayuki Ise, Kenya Kusunose, Takeshi Tobiume, Tomomi Matsuura, Koji Yamaguchi, Takeshi Soeki, Tetsuzo Wakatsuki, H Hata and Masataka Sata :
Infective Endocarditis from Furuncle with Meningitis Complication Caused by Methicillin-resistant Staphylococcus aureus,
Internal Medicine, Vol.60, No.20, 3251-3255, 2021.

(徳島大学機関リポジトリ): ● Metadata: 118014
(出版サイトへのリンク): ● Publication site (DOI): 10.2169/internalmedicine.6902-20
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 33867390; ● Search Scopus @ Elsevier (PMID): 33867390; ● Search Scopus @ Elsevier (DOI): 10.2169/internalmedicine.6902-20

(徳島大学機関リポジトリ: 118014, DOI: 10.2169/internalmedicine.6902-20, PubMed: 33867390) Yuta Torii, Kenya Kusunose, Yukina Hirata, Susumu Nishio, Takayuki Ise, Koji Yamaguchi, Daiju Fukuda, Shusuke Yagi, Hirotsugu Yamada, Takeshi Soeki, Tetsuzo Wakatsuki and Masataka Sata :
Left Atrial Strain Associated with Functional Recovery in Patients Receiving Optimal Treatment for Heart Failure,
Journal of the American Society of Echocardiography, Vol.34, No.9, 966-975, 2021.

(要約): Heart failure with recovered ejection fraction (HFrecEF) has been reported in several previous studies to have a better prognosis than heart failure with reduced ejection fraction (HFrEF). However, the factors associated with HFrecEF have not been identified. The aim of this study was to test the hypothesis that left atrial (LA) strain could help identify patients with recovered ejection fraction (EF) among those with heart failure (HF) with low EF on admission. One hundred consecutive patients hospitalized for the first time for new-onset HF were enrolled. Patients were clinically diagnosed with HFrEF on admission (left ventricular EF < 40%) and received optimal treatment for HF. Twenty-eight patients improved to HFrecEF during 6 months of follow-up. Regarding clinical background, there were significantly more women and a lower rate of atrial fibrillation in the HFrecEF group than in the HFrEF group. In a multivariate logistic regression analysis, LA strain was an independent predictor of HFrecEF, even after adjustment for gender and left ventricular EF (odds ratio: 4.06; 95% CI: 2.04-8.07; P < .001). A cutoff value of 10.8% for LA strain showed high sensitivity (96%) and specificity (82%) in identifying HFrecEF in patients with HF presenting with low EF on admission. During a follow-up period of 24 ± 13 months, 31 patients (31%) had cardiovascular death or readmission for HF. Patients with reduced LA strain (<10.8%) had significantly shorter event-free survival than those with preserved LA strain (P = .02). LA strain is a useful indicator for predicting HFrecEF and should be considered as a routine measurement in patients with HFrEF on admission.
(出版サイトへのリンク): ● Publication site (DOI): 10.1016/j.echo.2021.03.016
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 33852960; ● Search Scopus @ Elsevier (PMID): 33852960; ● Search Scopus @ Elsevier (DOI): 10.1016/j.echo.2021.03.016

(DOI: 10.1016/j.echo.2021.03.016, PubMed: 33852960) Tomomi Matsuura, Takeshi Soeki, Daiju Fukuda, Etsuko Uematsu, Takeshi Tobiume, Tomoya Hara, Kenya Kusunose, Takayuki Ise, Koji Yamaguchi, Shusuke Yagi, Hirotsugu Yamada, Tetsuzo Wakatsuki and Masataka Sata :
Activated Factor X Signaling Pathway via Protease-Activated Receptor 2 Is a Novel Therapeutic Target for Preventing Atrial Fibrillation,
Circulation Journal, Vol.85, No.8, 1383-1391, 2021.

(要約): Activated factor X (FXa), which contributes to chronic inflammation via protease-activated receptor 2 (PAR2), might play an important role in atrial fibrillation (AF) arrhythmogenesis. This study aimed to assess whether PAR2 signaling contributes to AF arrhythmogenesis and whether rivaroxaban ameliorates atrial inflammation and prevents AF.Methods and Results:In Study 1, PAR2 deficient (PAR2-/-) and wild-type mice were infused with angiotensin II (Ang II) or a vehicle via an osmotic minipump for 2 weeks. In Study 2, spontaneously hypertensive rats (SHRs) were treated with rivaroxaban, warfarin, or vehicle for 2 weeks after 8 h of right atrial rapid pacing. The AF inducibility and atrial remodeling in both studies were examined. Ang II-treated PAR2-/- mice had a lower incidence of AF and less mRNA expression of collagen1 and collagen3 in the atrium compared to wild-type mice treated with Ang II. Rivaroxaban significantly reduced AF inducibility compared with warfarin or vehicle. In SHRs treated with a vehicle, rapid atrial pacing promoted gene expression of inflammatory and fibrosis-related biomarkers in the atrium. Rivaroxaban, but not warfarin, significantly reduced expression levels of these genes. The FXa-PAR2 signaling pathway might contribute to AF arrhythmogenesis associated with atrial inflammation. A direct FXa inhibitor, rivaroxaban, could prevent atrial inflammation and reduce AF inducibility, probably by inhibiting the pro-inflammatory activation.
(徳島大学機関リポジトリ): ● Metadata: 116065
(出版サイトへのリンク): ● Publication site (DOI): 10.1253/circj.CJ-20-1006
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 33746155; ● Summary page in Scopus @ Elsevier: 2-s2.0-85111576585

(徳島大学機関リポジトリ: 116065, DOI: 10.1253/circj.CJ-20-1006, PubMed: 33746155, Elsevier: Scopus) Y Okushi, Kenya Kusunose, Y Okayama, Robert Zheng, M Nakai, Y Sumita, Takayuki Ise, Takeshi Tobiume, Koji Yamaguchi, Shusuke Yagi, Daiju Fukuda, Hirotsugu Yamada, Takeshi Soeki, Tetsuzo Wakatsuki and Masataka Sata :
Acute Hospital Mortality of Venous Thromboembolism in Patients With Cancer From Registry Data,
Journal of the American Heart Association, Vol.10, No.11, e019373, 2021.

(要約): Background The prognosis of patients with cancer-venous thromboembolism (VTE) is not well known because of a lack of registry data. Moreover, there is also no knowledge on how specific types are related to prognosis. We sought to evaluate the clinical characteristics and outcomes of patients with cancer-associated VTE, compared with a matched cohort without cancer using real-world registry data of VTE. Methods and Results This study was based on the Diagnosis Procedure Combination database in the JROAD-DPC (Japanese Registry of All Cardiac and Vascular Diseases and the Diagnosis Procedure Combination). Of 5 106 151 total patients included in JROAD-DPC, we identified 49 580 patients who were first hospitalized with VTE from April 2012 to March 2017. Propensity score was estimated with a logistic regression model, with cancer as the dependent variable and 18 clinically relevant covariates. After propensity matching, there were 25 148 patients with VTE with or without cancer. On propensity score-matched analysis with 25 148 patients with VTE, patients with cancer had higher total in-hospital mortality within 7 days (1.3% versus 1.1%, odds ratio [OR], 1.66; 95% CI, 1.31-2.11; <0.0001), 14 days (2.5% versus 1.5%, OR, 2.07; 95% CI, 1.72-2.49; <0.0001), and 30 days (4.8% versus 2.0%, OR, 2.85; 95% CI, 2.45-3.31; <0.0001). On analysis for each type of cancer, in-hospital mortality in 11 types of cancer was significantly high, especially pancreas (OR, 12.96; 95% CI, 6.41-26.20), biliary tract (OR, 8.67; 95% CI, 3.00-25.03), and liver (OR, 7.31; 95% CI, 3.05-17.50). Conclusions Patients with cancer had a higher in-hospital acute mortality for VTE than those without cancer, especially in pancreatic, biliary tract, and liver cancers.
(徳島大学機関リポジトリ): ● Metadata: 116140
(出版サイトへのリンク): ● Publication site (DOI): 10.1161/JAHA.120.019373
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 34027673; ● Search Scopus @ Elsevier (PMID): 34027673; ● Search Scopus @ Elsevier (DOI): 10.1161/JAHA.120.019373

(徳島大学機関リポジトリ: 116140, DOI: 10.1161/JAHA.120.019373, PubMed: 34027673) Miharu Arase, Kenya Kusunose, N Yamaguchi, Yukina Hirata, Susumu Nishio, Y Okushi, Takayuki Ise, Takeshi Tobiume, Koji Yamaguchi, Daiju Fukuda, Shusuke Yagi, Hirotsugu Yamada, Takeshi Soeki, Tetsuzo Wakatsuki and Masataka Sata :
Cardiac reserve by 6-minute walk stress echocardiography in systemic sclerosis.,
Open Heart, Vol.8, No.1, e001559, 2021.

(徳島大学機関リポジトリ): ● Metadata: 116465
(出版サイトへのリンク): ● Publication site (DOI): 10.1136/openhrt-2020-001559
(文献検索サイトへのリンク): ● Search Scopus @ Elsevier (DOI): 10.1136/openhrt-2020-001559

(徳島大学機関リポジトリ: 116465, DOI: 10.1136/openhrt-2020-001559) Kenya Kusunose, Y Okushi, Y Okayama, Robert Zheng, M Abe, M Nakai, Y Sumita, Takayuki Ise, Takeshi Tobiume, Koji Yamaguchi, Shusuke Yagi, Daiju Fukuda, Hirotsugu Yamada, Takeshi Soeki, Tetsuzo Wakatsuki and Masataka Sata :
Association between Vitamin D and Heart Failure Mortality in 10,974 Hospitalized Individuals.,
Nutrients, Vol.13, No.2, 335, 2021.

(要約): A broad range of chronic conditions, including heart failure (HF), have been associated with vitamin D deficiency. Existing clinical trials involving vitamin D supplementation in chronic HF patients have been inconclusive. We sought to evaluate the outcomes of patients with vitamin D supplementation, compared with a matched cohort using real-world big data of HF hospitalization. This study was based on the Diagnosis Procedure Combination database in the Japanese Registry of All Cardiac and Vascular Datasets (JROAD-DPC). After exclusion criteria, we identified 93,692 patients who were first hospitalized with HF between April 2012 and March 2017 (mean age was 79 ± 12 years, and 52.2% were male). Propensity score (PS) was estimated with logistic regression model, with vitamin D supplementation as the dependent variable and clinically relevant covariates. On PS-matched analysis with 10,974 patients, patients with vitamin D supplementation had lower total in-hospital mortality (6.5 vs. 9.4%, odds ratio: 0.67, < 0.001) and in-hospital mortality within 7 days and 30 days (0.9 vs. 2.5%, OR, 0.34, and 3.8 vs. 6.5%, OR: 0.56, both < 0.001). In the sub-group analysis, mortalities in patients with age < 75, diabetes, dyslipidemia, atrial arrhythmia, cancer, renin-angiotensin system blocker, and β-blocker were not affected by vitamin D supplementation. Patients with vitamin D supplementation had a lower in-hospital mortality for HF than patients without vitamin D supplementation in the propensity matched cohort. The identification of specific clinical characteristics in patients benefitting from vitamin D may be useful for determining targets of future randomized control trials.
(徳島大学機関リポジトリ): ● Metadata: 116464
(出版サイトへのリンク): ● Publication site (DOI): 10.3390/nu13020335
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 33498709; ● Summary page in Scopus @ Elsevier: 2-s2.0-85099832739

(徳島大学機関リポジトリ: 116464, DOI: 10.3390/nu13020335, PubMed: 33498709, Elsevier: Scopus) Akira Takashima, Shusuke Yagi, Koji Yamaguchi, Kiyoe Kurahashi, Yuko Kojima, Robert Zheng, Takayuki Ise, Kenya Kusunose, Sumiko Yoshida, Hirotsugu Yamada, Takeshi Soeki, Tetsuzo Wakatsuki, Ken-ichi Aihara, Masashi Akaike and Masataka Sata :
Congenital Hypogonadotropic Hypogonadism with Early-Onset Coronary Artery Disease.,
The Journal of Medical Investigation : JMI, Vol.68, No.1.2, 189-191, 2021.

(要約): The patient with congenital hypogonadotropic hypogonadism (HH) shows low serum levels of androgen, which is a group of sex hormones including testosterone, caused by the decreased gonadotropin release in the hypothalamus. Recent reports showed androgens exert protective effects against insulin resistance or atherosclerotic diseases, such as diabetes mellitus or coronary artery disease. However, whether the juvenile hypogonadism affects the diabetes or cardiovascular disease is unclear. We report a case of a middle-aged man with congenital HH who had severe coronary artery disease complicated with metabolic disorders. J. Med. Invest. 68 : 189-191, February, 2021.
(徳島大学機関リポジトリ): ● Metadata: 116019
(出版サイトへのリンク): ● Publication site (DOI): 10.2152/jmi.68.189
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 33994469; ● Search Scopus @ Elsevier (PMID): 33994469; ● Search Scopus @ Elsevier (DOI): 10.2152/jmi.68.189

(徳島大学機関リポジトリ: 116019, DOI: 10.2152/jmi.68.189, PubMed: 33994469) Yutaka Kawabata, Takeshi Soeki, Hiroyuki Ito, Tomomi Matsuura, Kenya Kusunose, Takayuki Ise, Koji Yamaguchi, Takeshi Tobiume, Shusuke Yagi, Daiju Fukuda, Hirotsugu Yamada, Tetsuzo Wakatsuki, M Kitani, K Kawano, Y Taketani and Masataka Sata :
Effects of L-/N-Type Calcium Channel Blockers on Angiotensin II-Renin Feedback in Hypertensive Patients,
International Journal of Hypertension, 6653851, 2020.

(徳島大学機関リポジトリ): ● Metadata: 115937
(出版サイトへのリンク): ● Publication site (DOI): 10.1155/2020/6653851
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 33489354; ● Summary page in Scopus @ Elsevier: 2-s2.0-85098701678

(徳島大学機関リポジトリ: 115937, DOI: 10.1155/2020/6653851, PubMed: 33489354, Elsevier: Scopus) Takeshi Tobiume, R Kato, Tomomi Matsuura, Kazuhisa Matsumoto, M Hara, N Takamori, Y Taketani, K Okwa, Takayuki Ise, Kenya Kusunose, Koji Yamaguchi, Shusuke Yagi, Daiju Fukuda, Hirotsugu Yamada, Tetsuzo Wakatsuki, Takeshi Soeki, Masataka Sata and K Matsumoto :
Antegrade slow pathway mapping of typical atrioventricular nodal reentrant tachycardia based on direct slow pathway capture,
Journal of Arrhythmia, Vol.37, No.1, 128-139, 2020.

(徳島大学機関リポジトリ): ● Metadata: 116343
(出版サイトへのリンク): ● Publication site (DOI): 10.1002/joa3.12484
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 33664895; ● Summary page in Scopus @ Elsevier: 2-s2.0-85099515348

(徳島大学機関リポジトリ: 116343, DOI: 10.1002/joa3.12484, PubMed: 33664895, Elsevier: Scopus) Kenya Kusunose, nao Yamada, Hirotsugu Yamada, Susumu Nishio, Yoshihito Saijoh, Yukina Hirata, Yuta Torii, Takayuki Ise, Koji Yamaguchi, Daiju Fukuda, Shusuke Yagi, Takeshi Soeki, Tetsuzo Wakatsuki and Masataka Sata :
Association between Right Ventricular Contractile Function and Cardiac Events in Isolated Post-capillary and Combined Pre- and Post-capillary Pulmonary Hypertension,
Journal of Cardiac Failure, Vol.26, No.1, 43-51, 2020.

(要約): Recent studies have shown that patients with combined pre- and postcapillary pulmonary hypertension (CpcPH) had worse outcomes than those with isolated postcapillary pulmonary hypertension (IpcPH). However, the prognostic factors including right ventricular (RV) function have not been well documented. The aim of this study was to assess the differentiation of PH phenotypes, using echocardiography, and the association between RV longitudinal strain and cardiac events. We prospectively recruited consecutive patients who had undergone right heart catheterization. The primary endpoint was cardiovascular death or readmission due to heart failure. We included 137 patients with Group 2 PH. A RV longitudinal strain of 17% was sensitive (85%) and specific (70%) to determine the CpcPH. During a median period of 31 months, 43 patients experienced the primary endpoint during follow-up. In a multivariate analysis, RV longitudinal strain was associated with the primary endpoint in both CpcPH and IpcPH (HR: 0.84, P = 0.003; HR: 0.86, P = 0.001). Lower RV longitudinal strain was independently associated with worse outcomes in CpcPH and IpcPH. RV longitudinal strain may play a prognostic role in PH phenotypes.
(徳島大学機関リポジトリ): ● Metadata: 114190
(出版サイトへのリンク): ● Publication site (DOI): 10.1016/j.cardfail.2019.08.021
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 31487533; ● Summary page in Scopus @ Elsevier: 2-s2.0-85072539026

(徳島大学機関リポジトリ: 114190, DOI: 10.1016/j.cardfail.2019.08.021, PubMed: 31487533, Elsevier: Scopus) Yuta Torii, Kenya Kusunose, Robert Zheng, Hirotsugu Yamada, Rie Amano, Rikizo Matsumoto, Yukina Hirata, Susumu Nishio, Nao Yamada, Takayuki Ise, Koji Yamaguchi, Takeshi Tobiume, Daiju Fukuda, Shusuke Yagi, Takeshi Soeki, Tetsuzo Wakatsuki, Yoshihiro Okayama and Masataka Sata :
Association between Sarcopenia/Lower Muscle Mass and Short-Term Regression of Deep Vein Thrombosis Using Direct Oral Anticoagulants,
International Heart Journal, Vol.61, No.4, 787-794, 2020.

(要約): Advanced age, obesity, and muscle weakness are independent factors in the onset of deep vein thrombosis (DVT). Recently, an association between sarcopenia and DVT has been reported. We hypothesized that sarcopenia related factors, observed by ultrasonography, are associated with the regression effect on the thrombus following anticoagulation therapy. The present study focused on gastrocnemius muscle (GCM) thickness and the GCM's internal echogenic brightness. We examined the association with DVT regression following direct oral anticoagulants (DOACs) treatment.The prospective cohort study period was between October 2017 and August 2018. We enrolled 46 patients diagnosed with DVT by ultrasonography, who were aged >60 years old and treated with DOACs. Sarcopenia was evaluated using the Asian Working Group for Sarcopenia flowchart. The average DOACs treatment period was 94 days, and 29 patients exhibited thrombus regression. On univariate logistic regression analysis, sarcopenia, average GCM diameter index, and gastrocnemius integrated backscatter index were significantly associated with thrombus regression. In a multivariate model, only the average GCM diameter index correlated with thrombus regression.The average GCM diameter index is associated with DVT regression treated with DOACs. Considering the GCM diameter during DVT treatment can be a marker to make a decision for the treatment of DVT.
(キーワード): Aged / Aged, 80 and over / Factor Xa Inhibitors / 女性 (female) / Humans / 男性 (male) / Middle Aged / Muscle, Skeletal / Prospective Studies / Sarcopenia / Ultrasonography / Venous Thrombosis
(出版サイトへのリンク): ● Publication site (DOI): 10.1536/ihj.20-032
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 32684602; ● Summary page in Scopus @ Elsevier: 2-s2.0-85088879684

(DOI: 10.1536/ihj.20-032, PubMed: 32684602, Elsevier: Scopus) Kenya Kusunose, M Fujiwara, Hirotsugu Yamada, Susumu Nishio, Y Saijo, N Yamada, Yukina Hirata, Yuta Torii, Takayuki Ise, Koji Yamaguchi, Daiju Fukuda, Shusuke Yagi, Takeshi Soeki, Tetsuzo Wakatsuki and Masataka Sata :
Deterioration of Biventricular Strain Is an Early Marker of Cardiac Involvement in Confirmed Sarcoidosis,
European Heart Journal Cardiovascular Imaging, Vol.21, No.7, 796-804, 2020.

(要約): Risk assessment of developing cardiac involvement in systemic sarcoidosis can be challenging because of limited data. Recently, attention has been given to left ventricular and right ventricular (LV and RV) involvement in cardiac sarcoidosis (CS) and its prevalence, relevance, and prognostic value. The aim of this study was to assess the role of biventricular strain to predict prognosis in confirmed sarcoidosis patients. LV and RV longitudinal strains (LSs) were evaluated by 2D speckle tracking in 139 consecutive confirmed sarcoidosis patients without other pre-existing structural heart diseases, and 52 age- and gender-matched control subjects. The primary endpoint was CS-related events (cardiac death or development of cardiac involvement). Sarcoidosis without cardiac involvement had significantly lower LV and RV free wall LS compared with control subjects. Basal LS had a higher area under the curve for differentiation of sarcoidosis in patients without cardiac involvement compared to control (cut-off value: -18% with 89% sensitivity and 69% specificity). During a median period of 50 months, the occurrence of CS-related events was observed in 20 patients. In a multivariate analysis, basal LV LS and RV free wall LS were associated with the events [hazard ratio (HR) 0.72, P < 0.001 and HR: 0.83, P = 0.006, respectively]. Patients with impaired biventricular function had significantly shorter event-free survival than those with preserved biventricular function (P < 0.001). Deterioration of biventricular strain was associated with CS-related events. This information might be useful for clinical evaluation and follow-up in sarcoidosis.
(出版サイトへのリンク): ● Publication site (DOI): 10.1093/ehjci/jez235
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 31566217; ● Summary page in Scopus @ Elsevier: 2-s2.0-85086792785

(DOI: 10.1093/ehjci/jez235, PubMed: 31566217, Elsevier: Scopus) Hiroyuki Ito, Tetsuzo Wakatsuki, Koji Yamaguchi, Daiju Fukuda, Yutaka Kawabata, Tomomi Matsuura, Kenya Kusunose, Takayuki Ise, Takeshi Tobiume, Shusuke Yagi, Hirotsugu Yamada, Takeshi Soeki, Yoshihiro Tsuruo and Masataka Sata :
Atherosclerotic Coronary Plaque Is Associated With Adventitial Vasa Vasorum and Local Inflammation in Adjacent Epicardial Adipose Tissue in Fresh Cadavers,
Circulation Journal, Vol.84, No.5, 769-775, 2020.

(徳島大学機関リポジトリ): ● Metadata: 116640
(出版サイトへのリンク): ● Publication site (DOI): 10.1253/circj.CJ-19-0914
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 32281556; ● Summary page in Scopus @ Elsevier: 2-s2.0-85083919450

(徳島大学機関リポジトリ: 116640, DOI: 10.1253/circj.CJ-19-0914, PubMed: 32281556, Elsevier: Scopus) Kenya Kusunose, Yuta Torii, Hirotsugu Yamada, Susumu Nishio, Yukina Hirata, Yoshihito Saijoh, Takayuki Ise, Koji Yamaguchi, Daiju Fukuda, Shusuke Yagi, Takeshi Soeki, Tetsuzo Wakatsuki and Masataka Sata :
Association of Echocardiography Before Major Elective Non-Cardiac Surgery With Improved Postoperative Outcomes - Possible Implications for Patient Care.,
Circulation Journal, Vol.83, No.12, 2512-2519, 2019.

(要約): Whether preoperative echocardiography improves postoperative outcomes is not well established, so we examined the value of echocardiographic assessment on the onset of postoperative heart failure (HF), and determining which patients benefitted most from undergoing echocardiography prior to major elective non-cardiac surgery.Methods and Results:We identified all patients aged 50 years and older who had major elective non-cardiac surgery, and excluded patients with previously identified severe cardiovascular disease. The primary endpoint was the onset of HF during hospitalization. A total of 806 patients were included in the analysis. During hospitalization, 49 patients (6%) reached the primary endpoint. Within the matched cohort, preoperative echocardiography was associated with a statistically significant decrease in postoperative HF (hazard ratio: 0.46, P=0.01). In subgroup analyses, age, sex, body surface area, hypertension, diabetes mellitus, prior HF, surgical type, chronic kidney disease, pulmonary disease, and malignancy influenced the association of echocardiography with postoperative HF. The use of echocardiography in elderly patients with certain risk factors was associated with improved postoperative outcomes. The basis for this finding remains to be determined; particularly whether echocardiography is simply a marker of a population with better outcomes or whether it leads to better management that improves outcomes.
(キーワード): Aged / Echocardiography / Female / Heart Failure / Humans / Incidence / Japan / Male / Middle Aged / Predictive Value of Tests / Preoperative Care / Retrospective Studies / Risk Assessment / Risk Factors / Surgical Procedures, Operative / Time Factors / Treatment Outcome
(徳島大学機関リポジトリ): ● Metadata: 114189
(出版サイトへのリンク): ● Publication site (DOI): 10.1253/circj.CJ-19-0663
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 31611537; ● Search Scopus @ Elsevier (PMID): 31611537; ● Search Scopus @ Elsevier (DOI): 10.1253/circj.CJ-19-0663

(徳島大学機関リポジトリ: 114189, DOI: 10.1253/circj.CJ-19-0663, PubMed: 31611537) Kenya Kusunose, Hirotsugu Yamada, Susumu Nishio, Yukina Hirata, Yoshihito Saijoh, Yuta Torii, nao Yamada, Takayuki Ise, Koji Yamaguchi, Daiju Fukuda, Shusuke Yagi, Takeshi Soeki, Tetsuzo Wakatsuki and Masataka Sata :
Pulmonary Artery Hypertension-Specific Therapy Improves Exercise Tolerance and Outcomes in Exercise-Induced Pulmonary Hypertension,
JACC. Cardiovascular Imaging, Vol.12, No.12, 2576-2579, 2019.

(徳島大学機関リポジトリ): ● Metadata: 114191
(出版サイトへのリンク): ● Publication site (DOI): 10.1016/j.jcmg.2019.07.002
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 31422131; ● Search Scopus @ Elsevier (PMID): 31422131; ● Search Scopus @ Elsevier (DOI): 10.1016/j.jcmg.2019.07.002

(徳島大学機関リポジトリ: 114191, DOI: 10.1016/j.jcmg.2019.07.002, PubMed: 31422131) Yuta Torii, Kenya Kusunose, Hirotsugu Yamada, Susumu Nishio, Yukina Hirata, Amano Rie, Yamao Masami, Zheng Robert, Yoshihito Saijoh, nao Yamada, Takayuki Ise, Koji Yamaguchi, Shusuke Yagi, Takeshi Soeki, Tetsuzo Wakatsuki and Masataka Sata :
Updated Left Ventricular Diastolic Function Recommendations and Cardiovascular Events in Patients with Heart Failure Hospitalization,
Journal of the American Society of Echocardiography, Vol.32, No.10, 1286-1297, 2019.

(要約): Evaluation of diastolic dysfunction is crucial in determining elevated left atrial pressure. However, a validation of the long-term prognostic value of the newly proposed algorithm updated in 2016 has not been performed. The aim of the present study was to investigate the relative value of the updated 2016 diastolic dysfunction grading system for the incidence of readmission in patients with heart failure (HF) with reduced ejection fraction (HFrEF) and HF with preserved ejection fraction (HFpEF). Two hundred thirty-two patients hospitalized with HF were retrospectively evaluated. Subjects were divided into two subgroups: those with HFrEF (n = 127) and those with HFpEF (n = 105). Readmission risk scores were calculated using the Yale Center for Outcomes Research and Evaluation HF, LACE index, and HOSPITAL scores. The primary end point was readmission following HF and cardiac death. Over a period of 24 months, 86 patients were either readmitted or died. Multivariate Cox analysis was performed on both the HFrEF and HFpEF groups. In the HFrEF group, both the 2009 and 2016 algorithms had superior incremental value for the association of the primary end point to several readmission risk scores. In the HFpEF group, only the 2016 algorithm led to significant improvement in association with the primary end point. The 2016 algorithm had incremental value over several readmission risk scores alone. The recommendations of the 2016 algorithm can be useful for readmission and cardiac mortality risk assessment in patients with HFrEF and HFpEF. The use of echocardiography to estimate elevated left atrial pressure appears to identify a higher risk group and may allow a more tailored approach to therapy.
(徳島大学機関リポジトリ): ● Metadata: 114193
(出版サイトへのリンク): ● Publication site (DOI): 10.1016/j.echo.2019.06.006
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 31378421; ● Summary page in Scopus @ Elsevier: 2-s2.0-85069976367

(徳島大学機関リポジトリ: 114193, DOI: 10.1016/j.echo.2019.06.006, PubMed: 31378421, Elsevier: Scopus) Shusuke Yagi, Daisuke Kondo, Takayuki Ise, Daiju Fukuda, Koji Yamaguchi, Tetsuzo Wakatsuki, Yutaka Kawabata, Hiroyuki Ito, Yoshihito Saijo, Hiromitsu Seno, Kumiko Sutou, Rie Ueno, Takafumi Todoroki, Kenya Kusunose, Tomomi Matsuura, Takeshi Tobiume, Hirotsugu Yamada, Takeshi Soeki, Michio Shimabukuro, Ken-ichi Aihara, Masashi Akaike and Masataka Sata :
Association of Decreased Docosahexaenoic Acid Level After Statin Therapy and Low Eicosapentaenoic Acid Level with In-Stent Restenosis in Patients with Acute Coronary Syndrome,
Journal of Atherosclerosis and Thrombosis, Vol.26, No.3, 272-281, 2019.

(要約): It is speculated that statin therapy modulates the synthesis of polyunsaturated fatty acids (PUFA), including eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). However, the data available on the effects of statin therapy on the serum levels of PUFA and the subsequent impact on in-stent restenosis (ISR) in patients with acute coronary syndrome (ACS) are limited. A total of 120 ACS patients who received emergent coronary stent implantation, follow-up coronary angiography to evaluate ISR, and new statin therapy were enrolled. We measured the serum levels of the PUFA and lipids at the onset of ACS and at the follow-up coronary angiography. The follow-up coronary angiography revealed 38 ISR cases. New statin therapy significantly reduced the serum levels of DHA and low-density lipoprotein cholesterol (LDL-C), while it did not affect EPA level. Single regression analysis revealed that a decreased serum level of LDL-C was associated with decreased DHA level. The multiple logistic regression analysis revealed that the decreased DHA level after statin therapy and low serum level of EPA on admission were determinants of prevalence of ISR. Statin therapy decreased the serum level of DHA with a parallel reduction in LDL-C level in patients with ACS. Decreased DHA level after statin therapy and low EPA level on admission are risk factors for ISR, indicating that in patients with ACS, decreased serum levels of DHA may be a residual target for the prevention of ISR.
(キーワード): Acute Coronary Syndrome / Aged / Coronary Restenosis / Docosahexaenoic Acids / Eicosapentaenoic Acid / 女性 (female) / Follow-Up Studies / Humans / Hydroxymethylglutaryl-CoA Reductase Inhibitors / 男性 (male) / Prognosis / Retrospective Studies / Risk Factors / Stents
(徳島大学機関リポジトリ): ● Metadata: 113220
(出版サイトへのリンク): ● Publication site (DOI): 10.5551/jat.44735
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 30135329; ● Summary page in Scopus @ Elsevier: 2-s2.0-85062425735

(徳島大学機関リポジトリ: 113220, DOI: 10.5551/jat.44735, PubMed: 30135329, Elsevier: Scopus) 高橋未奈, 飛梅威, 松本和久, 松浦朋美, 添木武, 藤本裕太, 原田貴文, Zheng Robert, 數藤久美子, 西條良仁, 上野理絵, 川端豊, 坂東美佳, 山田なお, 伊藤浩敬, 轟貴史, 伊勢孝之, 楠瀬賢也, 山口浩司, 八木秀介, 福田大受, 山田博胤, 若槻哲三, 佐田政隆 :
大動脈弁人工弁(機械弁)置換術後遠隔期に生じたOMI-VT stormに対し経心房中隔的に施行したカテーテルアブレーションが著効した1例,
四国医学雑誌, Vol.74, No.56, 201-208, 2019年.

(要約): A 68-year-old woman with VT storm and frequent appropriate ICD therapy was referred for catheter ablation. Her past history was notable for aortic valve replacement by mechanical valve due to infectious endocarditis 17 years prior to presentation and left ventricular apical old myocardial infarction with unknown onset. At 67 years old, She admitted to the prior hospital due to ventricular tachycardia with LBBB and superior axis at heart rate of 210 per minutes. Administration of amiodarone and magnesium sulfate was ineffective and cardioversion of 200J was successfully terminated the tachycardia. Intra-cardiac defibrillator was implanted and the administration of amiodarone and mexiletine was started. 5 months after, she admitted to the hospital due to the frequent appropriate shock against the same ventricular tachycardia. Administration of lidocaine, sotalol, pilsicainide, and magnesium sulfate could not control the tachycardia and she was referred to our hospital for catheter ablation. During the first session, ventricular tachycardia was easily induced and electroanatomical mapping was performed both during tachycardia and during sinus rhythm. Late diastolic potential preceding the onset of QRS wave by 45ms was detected at the infero-septal side of the apical aneurysm. 7 5s of the RF energy application at this site could terminate the tachycardia and thereafter no ventricular tachycardia was induced. But after dose-reduction or cessation of some anti-arrhythmic drugs, ventricular tachycardia was recurred and second session was performed. This time, no ventricular tachycardia was induced, then we performed isthmus transection and core isolation against the apical aneurysm. Thereafter no ventricular tachycardia was occurred in spite of dose-reduction or cessation of some anti-arrhythmic drugs.
(キーワード): ventricular tachycardia / storm / old myocardial infarction / catheter ablation / aortic valve replacement
(徳島大学機関リポジトリ): ● Metadata: 112988
(文献検索サイトへのリンク): ● CiNii @ 国立情報学研究所 (CRID): 1050001338015711104

(徳島大学機関リポジトリ: 112988, CiNii: 1050001338015711104) Shusuke Yagi, Robert Zheng, Seiichi Nishiyama, Yutaka Kawabata, Takayuki Ise, Kosuke Sugiura, Haruhiko Yoshinari, Toshihiko Nishisho, Yoshimi Bando, Kumiko Kagawa, Daiju Fukuda, Tomohiro Soga, Yoshihito Saijoh, Kenya Kusunose, Koji Yamaguchi, Hirotsugu Yamada, Takeshi Soeki, Tetsuzo Wakatsuki, Shinji Kawahito, Masashi Akaike and Masataka Sata :
Osteolytic primary bone lymphoma in the multiple bones,
The Journal of Medical Investigation : JMI, Vol.66, No.3,4, 347-350, 2019.

(要約): Primary non-Hodgkin bone lymphoma (PBL) can involve solitary or multiple destructive bone lesions such as those of the femur or pelvis humerus, and some cases have osteolytic lesions. PBL is a rare disease in adults. Thus, PBL is rarely considered a differential diagnosis of the osteolytic tumor. In addition, PBL can be underdiagnosed because patients do not experience symptoms or show objective abnormalities in the early stage. Here, we reported an elderly patient with PBL in multiple bones, including the cranial and femoral bones that were fractured due to falling. J. Med. Invest. 66 : 347-350, August, 2019.
(徳島大学機関リポジトリ): ● Metadata: 114167
(出版サイトへのリンク): ● Publication site (DOI): 10.2152/jmi.66.347
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 31656303; ● Summary page in Scopus @ Elsevier: 2-s2.0-85074142443

(徳島大学機関リポジトリ: 114167, DOI: 10.2152/jmi.66.347, PubMed: 31656303, Elsevier: Scopus) Shusuke Yagi, Itsuro Endo, Taichi Murakami, Tetsuya Hida, Yousuke Yamamoto, Tomohiro Soga, Takayuki Ise, Kenya Kusunose, Koji Yamaguchi, Daiju Fukuda, Hirotsugu Yamada, Takeshi Soeki, Tetsuzo Wakatsuki, Shinji Kawahito and Masataka Sata :
Adult onset of Immunoglobulin A vasculitis - A case report,,
The Journal of Medical Investigation : JMI, Vol.66, No.3,4, 344-346, 2019.

(要約): Immunoglobulin A vasculitis (IgAV), formerly known as Henoch-Schönlein purpura, primarily occurs during childhood between the ages of 3 and 15 years and is the most common form of systemic vasculitis in children ; its occurrence in adults has been rarely reported. Such low incidence could be attributable to either under-diagnosis or misdiagnosis. Thus, not only pediatricians but also physicians should be able to diagnose IgAV accurately to manage the patients appropriately and avoid its associated complications. In addition, treatment of adult onset IgAV with renal involvement has not been fully established yet. We describe here a case of adult onset IgAV complicated by proteinuria and pharyngitis, which was cured by no specific treatment. J. Med. Invest. 66 : 344-346, August, 2019.
(キーワード): Acetaminophen / Adult / Factor XIII / Humans / Immunoglobulin A / Male / Pharyngitis / Proteinuria / Purpura, Schoenlein-Henoch
(徳島大学機関リポジトリ): ● Metadata: 114166
(出版サイトへのリンク): ● Publication site (DOI): 10.2152/jmi.66.344
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 31656302; ● Search Scopus @ Elsevier (PMID): 31656302; ● Search Scopus @ Elsevier (DOI): 10.2152/jmi.66.344

(徳島大学機関リポジトリ: 114166, DOI: 10.2152/jmi.66.344, PubMed: 31656302) Shusuke Yagi, Rie Ueno, Kumiko Sutou, Tetsuzo Wakatsuki, Koji Yamaguchi, Yoshihito Saijo, Tomoya Hara, Takayuki Ise, Kenya Kusunose, Mika Bando, Tomomi Matsuura, Takeshi Tobiume, Hirotsugu Yamada, Daiju Fukuda, Takeshi Soeki, Masashi Akaike and Masataka Sata :
Lambda-like J wave due to acute myocardial infarction of the diagonal branch,
The Journal of Medical Investigation : JMI, Vol.66, No.1,2, 185-187, 2019.

(要約): The culprit lesion of acute myocardial infarction could be predicted by electrocardiogram findings. However, we experienced some cases with coronary angiographic finding in the area of ST-T elevation that was different from that predicted. The lambda-like J wave could be caused by ischemia although the mechanism has not been fully elucidated. We report a case of acute myocardial infarction that showed discrepancy between ST-T elevation with lambda-like ischemic J wave in a broad area and coronary angiographical finding of diagonal branch occlusion. J. Med. Invest. 66 : 185-187, February, 2019.
(徳島大学機関リポジトリ): ● Metadata: 113420
(出版サイトへのリンク): ● Publication site (DOI): 10.2152/jmi.66.185
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 31064936; ● Summary page in Scopus @ Elsevier: 2-s2.0-85065772885

(徳島大学機関リポジトリ: 113420, DOI: 10.2152/jmi.66.185, PubMed: 31064936, Elsevier: Scopus) Yoshihito Saijo, Hirotsugu Yamada, Kenya Kusunose, Mika Bando, Susumu Nishio, Yuta Torii, Yukina Hirata, Hiromitsu Seno, Tomomi Matsuura, Takayuki Ise, Takeshi Tobiume, Koji Yamaguchi, Shusuke Yagi, Takeshi Soeki, Tetsuzo Wakatsuki and Masataka Sata :
A clinical application of preload stress echocardiography for predicting future hemodynamic worsening in patients with early-stage heart failure.,
Echocardiography, Vol.35, No.10, 1587-1595, 2018.

(要約): To improve the prognosis of patients with heart failure, risk stratification in their early stage is important. We assessed whether the change in transmitral flow (TMF) velocity pattern during preload augmentation can predict future hemodynamic worsening in early-stage heart failure patients with impaired relaxation TMF pattern. We designed a prospective cohort study that included 155 consecutive patients with impaired relaxation (IR) pattern at rest. Preload stress echocardiography was achieved using leg-positive pressure (LPP), and changes in TMF pattern during the LPP was observed during baseline echocardiographic examination. The patients whose TMF pattern developed to pseudonormal (PN) pattern throughout the study period were classified into the change to PN group, and patients whose TMF pattern stayed in IR pattern were classified into the stay in IR group. The median follow-up period was 17 months. The average age was 68 ± 11 years old, and 97 patients (63%) were male. Among 155 patients, 27 were classified into the change to PN group. A Cox proportional hazard analysis confirmed that the change in the peak atrial systolic TMF velocity during the LPP (ΔA, hazard ratio = 0.58 per 1SD; 95% CI = 0.39-0.88, P = 0.010) was the powerful independent predictor of change into PN pattern. Kaplan-Meier analysis revealed that the patients with ΔA -7 cm/s had more likely to develop into PN pattern than patients with ΔA > -7 cm/s (P = 0.001). Evaluation of a response in TMF during the LPP might provide an incremental diagnostic value to detect future overt heart failure in patients with early-stage heart failure.
(徳島大学機関リポジトリ): ● Metadata: 112877
(出版サイトへのリンク): ● Publication site (DOI): 10.1111/echo.14098
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 30005132; ● Summary page in Scopus @ Elsevier: 2-s2.0-85054773574

(徳島大学機関リポジトリ: 112877, DOI: 10.1111/echo.14098, PubMed: 30005132, Elsevier: Scopus) Kenya Kusunose, Hiromitsu Seno, Hirotsugu Yamada, Susumu Nishio, Yuta Torii, Yukina Hirata, Y Saijo, Takayuki Ise, Koji Yamaguchi, Daiju Fukuda, Shusuke Yagi, Takeshi Soeki, Tetsuzo Wakatsuki and Masataka Sata :
Right Ventricular Function and Beneficial Effects of Cardiac Rehabilitation in Patients With Systolic Chronic Heart Failure.,
The Canadian Journal of Cardiology, Vol.34, No.10, 1307-1315, 2018.

(要約): It has been recognized that a comprehensive cardiac rehabilitation (CR) program improves mortality in patients with chronic heart failure. On the other hand, the magnitude of the improvement in exercise capacity after CR differs among individuals. The aim of this study was to assess the echocardiographic determinants of responders to CR using preload stress echocardiography. We prospectively enrolled 58 chronic heart failure patients with reduced left ventricular ejection fraction (aged 62 ± 11 years; 69% male; left ventricular ejection fraction 43% ± 7%) who had received optimized medical treatment in a CR program for 5 months. We performed preload echocardiographic studies using leg positive pressure (LPP) to assess the echocardiographic parameters during preload augmentation. We defined 41 patients as a development cohort to assess the predictive value of echocardiographic variables. Next, we validated results in the remaining 17 patients as a validation cohort. In the development cohort, significant improvement in peak oxygen uptake (VO) (>10%) after CR was observed in 58% patients. In a multivariable logistic regression model, the significant predictor of improvement in exercise capacity was right ventricular (RV) strain during LPP (odds ratio: 3.96 per 1 standard deviation; P = 0.01). An RV strain value of -16% during LPP had a good sensitivity of 0.79 and a specificity of 0.71 to identify patients with improvement in peak VO. In the validation cohort, an optimal cutoff value of RV strain value was the same (area under the curve: 0.77, sensitivity: 0.78, specificity: 0.65). RV strain during LPP may be an echocardiographic parameter for assessing beneficial effects of CR.
(徳島大学機関リポジトリ): ● Metadata: 114204
(出版サイトへのリンク): ● Publication site (DOI): 10.1016/j.cjca.2018.06.003
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 30146462; ● Summary page in Scopus @ Elsevier: 2-s2.0-85052061274

(徳島大学機関リポジトリ: 114204, DOI: 10.1016/j.cjca.2018.06.003, PubMed: 30146462, Elsevier: Scopus) Takeshi Soeki, Tomomi Matsuura, Takeshi Tobiume, Sachiko Bando, Matsumoto Kazuhisa, Hiromi Nagano, Etsuko Uematsu, Kenya Kusunose, Takayuki Ise, Koji Yamaguchi, Shusuke Yagi, Daiju Fukuda, Hirotsugu Yamada, Tetsuzo Wakatsuki, Michio Shimabukuro and Masataka Sata :
Clinical, Electrocardiographic, and Echocardiographic Parameter Combination Predicts the Onset of Atrial Fibrillation.,
Circulation Journal, Vol.82, No.9, 2253-2258, 2018.

(要約): The ability to identify risk markers for new-onset atrial fibrillation (AF) is critical to the development of preventive strategies, but it remains unknown whether a combination of clinical, electrocardiographic, and echocardiographic parameters predicts the onset of AF. In the present study, we evaluated the predictive value of a combined score that includes these parameters.Methods and Results:We retrospectively studied 1,040 patients without AF who underwent both echocardiography and 24-h Holter electrocardiography between May 2005 and December 2010. During a median follow-up period of 68.4 months (IQR, 49.9-93.3 months), we investigated the incidence of new-onset AF. Of the 1,040 patients, 103 (9.9%) developed AF. Patients who developed AF were older than patients who did not. Total heart beats, premature atrial contraction (PAC) count, maximum RR interval, and frequency of sinus pause quantified on 24-h electrocardiography were associated with new-onset AF. LA diameter (LAD) on echocardiography was also associated with the development of AF. On multivariate Cox analysis, age 58 years, PAC count 80 beats/day, maximum RR interval 1.64 s, and LAD 4.5 cm were independently associated with the development of AF. The incidence rate of new-onset AF significantly increased as the combined score (i.e., the sum of the risk score determined using hazard ratios) increased. A combined score that includes age, PAC count, maximum RR interval, and LAD could help characterize the risk of new-onset AF.
(徳島大学機関リポジトリ): ● Metadata: 113221
(出版サイトへのリンク): ● Publication site (DOI): 10.1253/circj.CJ-17-0758
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 29848884; ● Summary page in Scopus @ Elsevier: 2-s2.0-85052204332

(徳島大学機関リポジトリ: 113221, DOI: 10.1253/circj.CJ-17-0758, PubMed: 29848884, Elsevier: Scopus) Kenya Kusunose, Y Okushi, Hirotsugu Yamada, Susumu Nishio, Yuta Torii, Yukina Hirata, Y Saijo, Takayuki Ise, Koji Yamaguchi, Shusuke Yagi, Takeshi Soeki, Tetsuzo Wakatsuki and Masataka Sata :
Prognostic Value of Frailty and Diastolic Dysfunction in Elderly Patients.,
Circulation Journal, Vol.82, No.8, 2103-2110, 2018.

(要約): High prevalence of frailty and of diastolic dysfunction (DD) in heart failure and high mortality in frail adults have been noted. We characterized frailty by quantifying differences on echocardiography, and assessed the added prognostic utility of frailty and DD grade in an elderly population. One hundred and ninety-one patients 65 years who had at least 1 cardiovascular risk factor were prospectively recruited for clinically indicated echocardiography at the present institute. Weight loss, exhaustion, and deficits in physical activity, gait speed, and handgrip strength were used to categorize patients as frail (3 features), intermediately frail (1 or 2 features), or non-frail (0 features). DD grade 2 was defined as severe. Frailty was associated with larger left atrial volume, smaller stroke volume, and worse DD grade after adjustment for age. In a period of 14 months, 29 patients (15%) had cardiovascular events. The addition of frailty score and severe DD significantly improved the prognostic power of a model containing male gender (model 1, male gender, χ=6.4; model 2, model 1 plus frailty score, χ=16.7, P=0.004; model 3, model 2 plus severe DD, χ=25.5, P=0.015). Both frailty and DD grade were significantly associated with future cardiovascular events in an elderly population with preserved ejection fraction and 1 risk factor of cardiovascular disease.
(徳島大学機関リポジトリ): ● Metadata: 113222
(出版サイトへのリンク): ● Publication site (DOI): 10.1253/circj.CJ-18-0017
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 29709994; ● Summary page in Scopus @ Elsevier: 2-s2.0-85050588123

(徳島大学機関リポジトリ: 113222, DOI: 10.1253/circj.CJ-18-0017, PubMed: 29709994, Elsevier: Scopus) Gulinu Maimaituxun, Michio Shimabukuro, Daiju Fukuda, Shusuke Yagi, Yukina Hirata, Takashi Iwase, Shoichiro Takao, Tomomi Matsuura, Takayuki Ise, Kenya Kusunose, Takeshi Tobiume, Koji Yamaguchi, Hirotsugu Yamada, Takeshi Soeki, Tetsuzo Wakatsuki, Masafumi Harada and Masataka Sata :
Local Thickness of Epicardial Adipose Tissue Surrounding the Left Anterior Descending Artery Is a Simple Predictor of Coronary Artery Disease - New Prediction Model in Combination With Framingham Risk Score.,
Circulation Journal, Vol.82, No.5, 1369-1378, 2018.

(要約): Compared with global cardiac adiposity, the local accumulation of fat surrounding coronary arteries might have a more direct impact on coronary artery disease (CAD). Here, we compared the local epicardial adipose tissue (EAT) thickness and global cardiac adiposity volumes for predicting CAD.Methods and Results:A total of 197 consecutive subjects underwent 320-slice multi-detector computed tomography coronary angiography and were segregated into CAD (1 coronary artery branch stenosis 50%) and non-CAD groups. EAT thickness was measured at the right coronary artery (EAT), the left anterior descending artery (EAT), and the left circumflex artery (EAT). Although EATand EATwere similar between the 2 groups, EATwas larger in the CAD group than in the non-CAD group (5.45±2.16 mm vs. 6.86±2.19 mm, P<0.001). EAT, after correcting for confounding factors, was strongly associated with CAD (r=0.276, P<0.001) and Gensini score (r=0.239, P<0.001). On multiple regression analysis, Framingham risk score combined with EATwas a strong predictor of CAD (adjusted R=0.121; P<0.001). The local fat thickness surrounding the LAD is a simple and useful surrogate marker for estimating the presence, severity, and extent of CAD, independent of classical cardiovascular risk factors.
(徳島大学機関リポジトリ): ● Metadata: 112879
(出版サイトへのリンク): ● Publication site (DOI): 10.1253/circj.CJ-17-1289
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 29563352; ● Summary page in Scopus @ Elsevier: 2-s2.0-85045965929

(徳島大学機関リポジトリ: 112879, DOI: 10.1253/circj.CJ-17-1289, PubMed: 29563352, Elsevier: Scopus) Hiromu Yamazaki, Shusuke Yagi, Yuta Torii, Rie Amano, Yasuyuki Oomichi, Teruaki Sangawa, Daiju Fukuda, Muneyuki Kadota, Takayuki Ise, Rie Ueno, Tomoya Hara, Kenya Kusunose, Tomomi Matsuura, Takeshi Tobiume, Koji Yamaguchi, Hirotsugu Yamada, Takeshi Soeki, Tetsuzo Wakatsuki, Masashi Akaike and Masataka Sata :
Edoxaban improves acute venous thromboembolism while preserving protein C and protein S levels,
Journal of Cardiology, Vol.71, No.3, 305-309, 2017.

(要約): It is well known that warfarin inhibits the synthesis of vitamin K-dependent anticoagulants, including thrombin, protein C and S, and factor Xa, leading, paradoxically, to an initial hypercoagulable state. Edoxaban, a direct inhibitor of activated factor X is widely used for the treatment of acute venous thromboembolism (VTE). However, the effect of edoxaban on circulating coagulation factors, in patients with acute VTE, remains unknown. We enrolled 57 patients with acute VTE with/without pulmonary embolism treated with edoxaban (n=37) or warfarin (n=20) in a clinical setting. Before treatment and 2 weeks after treatment, we evaluated thrombotic burden using ultrasound or computed tomography angiography. We also evaluated thrombin generation, represented by prothrombin fragment F1+2; thrombus degradation, represented by D-dimer; and levels of anticoagulants, including protein C, protein S, and antithrombin III. Both edoxaban and warfarin treatment improved thrombotic burden and decreased prothrombin fragment F1+2, and D-dimer. Edoxaban treatment preserved protein C and protein S levels. In contrast, warfarin decreased protein C and protein S levels. Neither treatment affected antithrombin III. Edoxaban improves VTE while preserving protein C and protein S levels, thereby indicating that edoxaban improves thrombotic burden while maintaining levels of anticoagulants.
(出版サイトへのリンク): ● Publication site (DOI): 10.1016/j.jjcc.2017.09.009
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 29100817; ● Summary page in Scopus @ Elsevier: 2-s2.0-85032912457

(DOI: 10.1016/j.jjcc.2017.09.009, PubMed: 29100817, Elsevier: Scopus) Shusuke Yagi, Ken-ichi Aihara, Takeshi Kondo, Kiyoe Kurahashi, Sumiko Yoshida, Itsuro Endo, Daiju Fukuda, Yutaka Nakaya, Kin-Ichiro Suwaki, Takashi Takeji, Toshihiro Wada, Masdan Hotimah Salim, Saori Hama, Tomomi Matsuura, Takayuki Ise, Kenya Kusunose, Koji Yamaguchi, Takeshi Tobiume, Hirotsugu Yamada, Takeshi Soeki, Tetsuzo Wakatsuki, Munehide Matsuhisa, Michio Shimabukuro, Masashi Akaike and Masataka Sata :
Predictors for the Treatment Effect of Sodium Glucose Co-transporter 2 Inhibitors in Patients with Type 2 Diabetes Mellitus.,
Advances in Therapy, Vol.35, No.1, 124-134, 2017.

(要約): Predictors for the effect of sodium glucose co-transporter 2 (SGLT2) inhibitors at lowering hemoglobin A1c (HbA1c) levels in type 2 diabetes mellitus patients remain unclear. We therefore aimed to elucidate these predictors in type 2 diabetes patients after 3 months of SGLT2 treatment. A total of 302 consecutive type 2 diabetes patients who had been treated with SGLT2 inhibitors as monotherapy or add-on therapy to existing antidiabetic treatments were enrolled retrospectively. After excluding 27 patients whose HbA1c levels could not be evaluated 3 months after treatment, the glucose-lowering effects of SGLT2 inhibitors were assessed in 275 patients by measuring HbA1c levels before and 3 months after treatment. The predictors for changes in HbA1c levels after 3 months of treatment were evaluated. SGLT2 inhibitor treatment for 3 months decreased HbA1c levels from 7.8 ± 1.2% to 7.4 ± 1.0% (p < 0.0001). A multiple regression analysis showed that the independent determinants for SGLT2 inhibitor treatment effect included decreased HbA1c levels after 1 month of treatment, high baseline HbA1c levels, and a high estimated glomerular filtration rate (eGFR). We show that type 2 diabetes patients who received the greatest glucose-lowering effect with SGLT2 inhibitor treatment were those with preserved renal function (high baseline eGFR) and high baseline HbA1c levels. Moreover, SGLT2 inhibitor treatment efficacy could be predicted by the patients' initial response to treatment.
(出版サイトへのリンク): ● Publication site (DOI): 10.1007/s12325-017-0639-z
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 29185199; ● Summary page in Scopus @ Elsevier: 2-s2.0-85035102977

(DOI: 10.1007/s12325-017-0639-z, PubMed: 29185199, Elsevier: Scopus) Shusuke Yagi, Takeshi Soeki, Ken-Ichi Aihara, Daiju Fukuda, Takayuki Ise, Muneyuki Kadota, Sachiko Bando, Tomomi Matsuura, Takeshi Tobiume, Koji Yamaguchi, Kenya Kusunose, Hirotsugu Yamada, Tetsuzo Wakatsuki, Michio Shimabukuro, Masashi Akaike and Masataka Sata :
Low Serum Levels of Eicosapentaenoic Acid and Docosahexaenoic Acid are Risk Factors for Cardiogenic Syncope in Patients with Brugada Syndrome,
International Heart Journal, Vol.58, No.5, 720-723, 2017.

(要約): The n-3 polyunsaturated fatty acids (PUFAs), including eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), have antiarrhythmic effects, possibly via modulation of the cardiac ion channels. Nevertheless, it is unknown whether low serum levels of n-3 PUFAs are risk factors for ventricular fibrillation in patients with Brugada syndrome (BrS). We retrospectively reviewed data from 62 men with BrS and evaluated their serum levels of EPA and DHA, and the risk factors for sudden cardiac death, including a history of cardiogenic syncope. Nineteen patients had a history of cardiogenic syncope, and their EPA and DHA levels were significantly lower than those of the patients without syncope. Multivariate logistic regression analysis revealed that low EPA and DHA levels were associated with the incidence of syncope. The receiver-operator characteristic curve showed the area under the curves of EPA and DHA for history of syncope were 0.84 and 0.72, respectively. In conclusion, low levels of EPA and DHA are risk factors for cardiogenic syncope in patients with BrS, which suggests that n-3 PUFAs play important roles in preventing ventricular fibrillation in BrS.
(キーワード): Adult / Aged / Aged, 80 and over / Biomarkers / Brugada Syndrome / Chromatography, Gas / Docosahexaenoic Acids / Eicosapentaenoic Acid / Electrocardiography / Follow-Up Studies / Humans / Incidence / 日本 (Japan) / Male / Middle Aged / Prevalence / ROC Curve / Retrospective Studies / Risk Assessment / Risk Factors / Syncope / Young Adult
(出版サイトへのリンク): ● Publication site (DOI): 10.1536/ihj.16-278
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 28966307; ● CiNii @ 国立情報学研究所 (CRID): 1390282680202467328; ● Summary page in Scopus @ Elsevier: 2-s2.0-85032215381

(DOI: 10.1536/ihj.16-278, PubMed: 28966307, CiNii: 1390282680202467328, Elsevier: Scopus) Yuriko Takagawa, Shusuke Yagi, Takayuki Ise, Ayumi Ishii, Koji Nishikawa, Daiju Fukuda, Kenya Kusunose, Tomomi Matsuura, Takeshi Tobiume, Koji Yamaguchi, Hirotsugu Yamada, Takeshi Soeki, Tetsuzo Wakatsuki, Michio Shimabukuro, Shinsuke Katoh, Ken-ichi Aihara, Masashi Akaike and Masataka Sata :
Improved Exercise Capacity After Cardiac Rehabilitation Is Associated with Reduced Visceral Fat in Patients with Chronic Heart Failure.,
International Heart Journal, Vol.58, No.5, 746-751, 2017.

(要約): Participation in a comprehensive cardiac rehabilitation (CR) program has been shown to reduce mortality and improve exercise capacity and symptoms in patients with chronic heart failure (CHF). Reduced exercise capacity leads to a concomitant reduction of skeletal muscle mass and accumulation of body fat. However, it is currently unknown whether CR reduces visceral adipose tissue (VAT) and/or subcutaneous abdominal adipose tissue (SAT) in patients with CHF. In addition, the body composition associated with improved exercise capacity after CR in patients with CHF has not been previously studied. Nineteen CHF patients who were categorized as NYHA functional class II or III and had received optimal medical treatment including a CR program for 5 months were enrolled in this study. The CR program significantly increased peak VO and reduced B-type natriuretic peptide. In addition, fat and body composition analysis showed reductions in the visceral fat tissue (VAT) area, subcutaneous abdominal adipose tissue (SAT) area, body weight, and total fat weight after CR. There were no changes in total water weight and total muscle weight. Single regression analysis revealed that the amelioration of reduced exercise capacity seen after CR is associated with reduced VAT area but not with SAT area or body weight. In conclusion, CR reduces VAT and improves exercise capacity in patients with CHF. This suggests that reducing VAT is important for CR to be most effective in the treatment of CHF.
(キーワード): Body Composition / Cardiac Rehabilitation / Exercise Tolerance / Female / Follow-Up Studies / 心不全 (heart failure) / Humans / Intra-Abdominal Fat / Male / Middle Aged / 肥満症 (obesity) / 酸素消費 (oxygen consumption) / Prognosis / Retrospective Studies / Weight Loss
(徳島大学機関リポジトリ): ● Metadata: 110111
(出版サイトへのリンク): ● Publication site (DOI): 10.1536/ihj.16-454
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 28966316; ● Summary page in Scopus @ Elsevier: 2-s2.0-85032221042

(徳島大学機関リポジトリ: 110111, DOI: 10.1536/ihj.16-454, PubMed: 28966316, Elsevier: Scopus) Shusuke Yagi, Yukina Hirata, Takayuki Ise, Kenya Kusunose, Hirotsugu Yamada, Daiju Fukuda, Salim Masdan Hotimah, G Maimaituxun, Susumu Nishio, Yuriko Takagawa, Saori Hama, Tomomi Matsuura, Koji Yamaguchi, Takeshi Tobiume, Takeshi Soeki, Tetsuzo Wakatsuki, Ken-ichi Aihara, Masashi Akaike, Michio Shimabukuro and Masataka Sata :
Canagliflozin reduces epicardial fat in patients with type 2 diabetes mellitus.,
Diabetology & Metabolic Syndrome, Vol.9, 78, 2017.

(要約): It is unknown whether canagliflozin, a selective sodium glucose co-transporter 2 inhibitor, reduces epicardial adipose tissue (EAT) thickness, which is associated with insulin resistance and is a risk factor for coronary artery disease. We administered 100 mg of canagliflozin for 6 months to 13 patients with type 2 diabetes mellitus. We evaluated glycemic control, visceral adipose tissue (VAT) area and subcutaneous adipose tissue (SAT) area, and skeletal muscle mass by using impedance methods, and EAT thickness by using echocardiography. Canagliflozin treatment for 6 months decreased hemoglobin A1c level from 7.1 ± 0.5% to 6.7 ± 0.6% (P < 0.05) and decreased EAT thickness from 9.3 ± 2.5 to 7.3 ± 2.0 mm (P < 0.001), along with a trend of decreasing VAT and SAT area. No association was found between any of these changes. Canagliflozin reduced EAT thickness in patients with type 2 diabetes mellitus independent of its effect on lowering blood glucose, suggesting that canagliflozin may have an effect in preventing cardiovascular events in these patients (UMIN000021327).
(徳島大学機関リポジトリ): ● Metadata: 114544
(出版サイトへのリンク): ● Publication site (DOI): 10.1186/s13098-017-0275-4
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 29034006; ● Summary page in Scopus @ Elsevier: 2-s2.0-85030465923

(徳島大学機関リポジトリ: 114544, DOI: 10.1186/s13098-017-0275-4, PubMed: 29034006, Elsevier: Scopus) Kenya Kusunose, Hirotsugu Yamada, Susumu Nishio, Yuta Torii, Yukina Hirata, Hiromitsu Seno, Yoshihito Saijo, Takayuki Ise, Koji Yamaguchi, Shusuke Yagi, Takeshi Soeki, Tetsuzo Wakatsuki and Masataka Sata :
Preload Stress Echocardiography Predicts Outcomes in Patients With Preserved Ejection FractionandLow-GradientAorticStenosis,
Circulation. Cardiovascular Imaging, Vol.10, No.10, 2017.

(要約): The projected aortic valve area (AVA) at a normal transvalvular flow rate using dobutamine is helpful to determine the actual severity of aortic stenosis (AS) and to predict risk of adverse events in low-gradient AS cases with unclear surgical indication. Our study aimed to identify the independent and incremental value of preload stress echocardiography-derived AVA to predict outcomes in patients with preserved ejection fraction and low-gradient AS. We prospectively performed echocardiographic studies in 79 patients with low-gradient AS (age, 77±7 years; 30% men) with preload stress echocardiography using leg positive pressure. AVA was calculated using AVA and transvalvular flow rate at baseline and during leg positive pressure. The primary end point was the decision for aortic valve surgery or cardiac death. During a median period of 19 months, 23 patients had the decision for aortic valve surgery, and none died during follow-up. In a stepwise multivariable analysis, indexed AVA (AVAi; hazard ratio, 2.00 per 0.1 cm/m decrease; 95% confidence interval, 1.36-2.96; <0.001) was associated with the primary end point. Using a receiver operating characteristic curve analysis, the best cutoff value of AVAi for predicting cardiac events was <0.72 cm/m. By incorporating AVAi into AVAi at baseline, continuous net reclassification index for cardiac events was 0.48 (=0.04). In patients with low-gradient AS, indexed AVA derived from preload stress echocardiography can be useful to predict risk of adverse events. The present article should be considered as a proof of concept study, and we think that larger multicenter studies are warranted.
(キーワード): Aged / Aged, 80 and over / Aortic Valve / Aortic Valve Stenosis / Area Under Curve / Disease Progression / Disease-Free Survival / Echocardiography, Stress / Female / Humans / Kaplan-Meier Estimate / Male / Models, Cardiovascular / Predictive Value of Tests / Prospective Studies / ROC Curve / Severity of Illness Index / Stroke Volume / Time Factors / Ventricular Function, Left
(出版サイトへのリンク): ● Publication site (DOI): 10.1161/CIRCIMAGING.117.006690
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 29021259; ● Summary page in Scopus @ Elsevier: 2-s2.0-85031850278

(DOI: 10.1161/CIRCIMAGING.117.006690, PubMed: 29021259, Elsevier: Scopus) Susumu Nishio, Kenya Kusunose, Hirotsugu Yamada, Yukina Hirata, Takayuki Ise, Koji Yamaguchi, Shusuke Yagi, Takeshi Soeki, Tetsuzo Wakatsuki, Michio Shimabukuro and Masataka Sata :
Echocardiographic Epicardial Adipose Tissue Thickness Is Associated with Symptomatic Coronary Vasospasm during Provocative Testing.,
Journal of the American Society of Echocardiography, Vol.30, No.10, 1021-1027, 2017.

(要約): Epicardial adipose tissue (EAT) is the ectopic visceral fat surrounding the heart, which plays an important role in atherosclerosis of the coronary arteries via endothelial damage. Several studies have also suggested that vasospasm with angina (VSA) causes endothelial dysfunction in the coronary arteries. The aim of this study was to evaluate the thickness of EAT in the anterior interventricular groove (EAT-AIG) using echocardiography in patients who had no obstructive coronary artery disease and were suspected of having VSA. Sixty-five patients who underwent intracoronary acetylcholine provocation testing for clinical indications were prospectively enrolled. VSA was diagnosed by coronary artery stenosis increase of >90% and the presentation of chest pain with ischemic changes on electrocardiography. Subjects were divided into two groups, with and without significant coronary spasm (VSA group, 30 patients; non-VSA group, 35 patients), consistent with acetylcholine provocation testing. EAT-AIG thickness was significantly greater in the VSA group than in the non-VSA group (8.2 2.7 vs 6.1 2.5 mm, P = .002). By receiver operating characteristic analysis, EAT-AIG thickness had a high C statistic (area under the curve = 0.81, P < .001) after adjustment for conventional risk factors (smoking, diabetes mellitus, and dyslipidemia). EAT-AIG thickness had incremental diagnostic value over other conventional risk factors (area under the curve = 0.81 vs 0.64, P for comparison = .020). EAT-AIG thickness, which is noninvasively and easily measured using transthoracic echocardiography, can be one of multiple clinical variables associated with VSA.
(徳島大学機関リポジトリ): ● Metadata: 110928
(出版サイトへのリンク): ● Publication site (DOI): 10.1016/j.echo.2017.06.024
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 28843368; ● Search Scopus @ Elsevier (PMID): 28843368; ● Search Scopus @ Elsevier (DOI): 10.1016/j.echo.2017.06.024

(徳島大学機関リポジトリ: 110928, DOI: 10.1016/j.echo.2017.06.024, PubMed: 28843368) Kenya Kusunose, Hirotsugu Yamada, Susumu Nishio, Yukina Hirata, Hiromitsu Seno, Y Saijo, Takayuki Ise, Takeshi Tobiume, Koji Yamaguchi, Shusuke Yagi, Takeshi Soeki, Tetsuzo Wakatsuki and Masataka Sata :
Echocardiographic Predictors for Worsening of Six-Minute Walk Distances in Patients With Systemic Sclerosis (Scleroderma),
The American Journal of Cardiology, Vol.120, No.2, 315-321, 2017.

(要約): Change in 6-minute walk distance (6MWD) has been used as a clinical marker in pulmonary hypertension. Determinants and worsening of 6MWD remain a matter of debate because nonpulmonary factors have an impact on the 6MWD. We hypothesized that future reduction of 6MWD in patients with systemic sclerosis (SSc) was more closely associated with cardiac dysfunction. We prospectively performed standard clinical and echocardiographic evaluations in SSc patients with the 6-minute walk test at enrollment. Features associated with the 6MWD were sought in a multiple linear regression analysis and compared using standardized . Worsening of the 6MWD was defined as a 15% reduction and served as the primary outcome. Eighty-one patients were included. In the multivariate analysis, baseline 6MWD was related to SSc severity score ( = -0.250, p = 0.024), left atrial volume index ( = -0.222, p = 0.046), right ventricular fractional area change ( = 0.252, p = 0.025), and the ratio of mean pulmonary artery pressure and cardiac output ( = -0.31, p = 0.002). During follow-up, 20 patients reached the primary outcome. In sequential Cox models, a model based on right ventricular fractional area change at baseline (chi-square 4.8) was improved by left atrial volume index (chi-square 10.3, p = 0.007). In conclusion, determinants and worsening of 6MWD are explained by cardiac factors. When using the 6MWD as a clinical marker in pulmonary hypertension patients, their left ventricular diastolic function and right ventricular systolic function should be taken into consideration.
(キーワード): Diastole / Disease Progression / Echocardiography, Doppler / Female / Follow-Up Studies / Humans / Hypertension, Pulmonary / Male / Middle Aged / Predictive Value of Tests / Prospective Studies / Scleroderma, Systemic / Stroke Volume / Systole / Time Factors / Ventricular Function, Left / Ventricular Function, Right / Walking
(出版サイトへのリンク): ● Publication site (DOI): 10.1016/j.amjcard.2017.04.024
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 28532772; ● Search Scopus @ Elsevier (PMID): 28532772; ● Search Scopus @ Elsevier (DOI): 10.1016/j.amjcard.2017.04.024

(DOI: 10.1016/j.amjcard.2017.04.024, PubMed: 28532772) Kenya Kusunose, Hirotsugu Yamada, Susumu Nishio, Ayumi Ishii, Yukina Hirata, Hiromitsu Seno, Yoshihito Saijo, Takayuki Ise, Koji Yamaguchi, Shusuke Yagi, Takeshi Soeki, Tetsuzo Wakatsuki and Masataka Sata :
RV Myocardial Strain During Pre-Load Augmentation Is Associated With Exercise Capacity in Patients With Chronic HF,
JACC. Cardiovascular Imaging, Vol.10, No.10, 1240-1249, 2017.

(要約): The aim of this study was to assess the relationship between right ventricular (RV) function during pre-load augmentation and exercise tolerance. Peak oxygen uptake (VO2) is a strong predictor of mortality in chronic heart failure. Cardiac function during pre-load augmentation is an important part of the phenomenon in the evaluation of exercise capacity. We prospectively performed echocardiographic studies in 68 chronic heart failure patients with cardiopulmonary exercise testing (mean age 60 ± 12 years; 69% male). After resting evaluations, echocardiographic parameters were repeated during leg positive pressure (LPP). Exercise capacity was assessed by peak VO2 in all patients (left ventricular ejection fraction: 43 ± 15%). Patients with severely reduced exercise capacity (peak VO2 <14 ml/kg/min) had significantly lower stroke volume index, left ventricular global longitudinal strain and RV strain and higher filling pressure (E/e' and pulmonary arterial systolic pressure) than the remainder. Stroke volume index ( = 0.49), global longitudinal strain ( = -0.61), E/e' ( = -0.32), pulmonary arterial systolic pressure ( = -0.57), and RV strain ( = -0.66) during LPP were independently correlated to peak VO2 (all p < 0.01). RV strain during LPP was the most powerful predictor in identifying patients with severely reduced exercise capacity (cut off value: -17%; sensitivity: 81%; specificity: 88%; areas under the curve: 0.88; p < 0.001) compared with other variables including resting parameters. RV strain during pre-load augmentation correlated independently to peak VO2 and was a powerful predictor in identifying patients with severely reduced exercise capacity.
(出版サイトへのリンク): ● Publication site (DOI): 10.1016/j.jcmg.2017.03.022
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 28734918; ● Summary page in Scopus @ Elsevier: 2-s2.0-85025467938

(DOI: 10.1016/j.jcmg.2017.03.022, PubMed: 28734918, Elsevier: Scopus) S Bando, Takeshi Soeki, Tomomi Matsuura, Takeshi Tobiume, Takayuki Ise, Kenya Kusunose, Koji Yamaguchi, Shusuke Yagi, Daiju Fukuda, Takashi Iwase, Hirotsugu Yamada, Tetsuzo Wakatsuki, Michio Shimabukuro, Naoki Muguruma, Tetsuji Takayama, I Kishimoto, Kenji Kangawa and Masataka Sata :
Plasma brain natriuretic peptide levels are elevated in patients with cancer,
PLoS ONE, Vol.12, No.6, e0178607, 2017.

(要約): Natriuretic peptides have been proposed as biomarkers of cardiovascular disease, especially heart failure. Brain natriuretic peptide (BNP) has also been shown to be upregulated at the transcriptional and translational levels by pro-inflammatory cytokines in cardiac myocytes. Although we often measure plasma BNP levels in cancer patients, it remains unknown whether cancer-related inflammation affects the plasma BNP levels. We investigated the relationship between the BNP and human cancers. We retrospectively studied 2,923 patients in whom the plasma BNP levels and serum C-reactive protein (CRP) were measured and echocardiography was performed. Patients with clinically evident heart failure (NYHA II or higher), heart disease requiring medical treatment or surgery, renal dysfunction, and inflammatory disease were excluded. There were 234 patients in the final analysis. Blood sampling was performed before surgery and chemotherapy. In addition, we evaluated the relationship between the inflammation and plasma BNP levels in mouse models of colon cancer. Of the 234 patients, 80 were diagnosed with cancer. Both the plasma BNP and serum CRP levels were significantly higher in cancer patients than those without. There were no significant differences in the echocardiographic parameters. There was a significant positive correlation between the plasma BNP and serum CRP levels in cancer patients (r = 0.360, P<0.01) but not in those without. In cancer patients, only the CRP correlated with the BNP independent of the age, creatinine level, hypertension, and body mass index. In addition, in nude mice with subcutaneous colon cancer, the plasma BNP level was elevated compared with that in non-cancer mice, and there was a significant relationship between the plasma BNP and serum levels of the inflammatory markers. In cancer patients, as well as colon cancer model mice, the plasma BNP levels were elevated, possibly due to cancer-related inflammation. The effect of cancer on the BNP levels should be considered when using BNP as an indicator of heart failure in cancer patients.
(徳島大学機関リポジトリ): ● Metadata: 112318
(出版サイトへのリンク): ● Publication site (DOI): 10.1371/journal.pone.0178607
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 28570595; ● Search Scopus @ Elsevier (PMID): 28570595; ● Search Scopus @ Elsevier (DOI): 10.1371/journal.pone.0178607

(徳島大学機関リポジトリ: 112318, DOI: 10.1371/journal.pone.0178607, PubMed: 28570595) Kenya Kusunose, Yuta Torii, Hirotsugu Yamada, Susumu Nishio, Yukina Hirata, Hiromitsu Seno, Yoshihito Saijo, Takayuki Ise, Koji Yamaguchi, Takeshi Tobiume, Shusuke Yagi, Takeshi Soeki, Tetsuzo Wakatsuki and Masataka Sata :
Clinical Utility of Longitudinal Strain to Predict Functional Recovery in Patients With Tachyarrhythmia and Reduced LVEF.,
JACC. Cardiovascular Imaging, Vol.10, No.2, 118-126, 2017.

(要約): Objectives: The aim of this study was to assess the time course of presumptive TIC and the predictors of LV functional recovery in such patients.Background: Tachycardia-induced cardiomyopathy (TIC) is a potentially reversible cardiomyopathy with effective treatment of the tachyarrhythmia. However, cases without improvement of left ventricular (LV) systolic function were found occasionally. The diagnosis of TIC can be challenging, and the role of echocardiographic imaging in the prediction of LV functional recovery is limited.Methods: LV segmental longitudinal strains (LS) were evaluated by 2-dimensional speckle tracking in 71 consecutive patients (65±16 years; 61% men) with tachyarrhythmia and reduced LV ejection fraction (EF) without any other known cardiovascular disease, and 30 age and gender matched control subjects. Relative apical LS ratio (RALSR) was defined using the equation: average apical LS / (average basal LS + average mid LS) as a marker of strain distribution.Results: Compared to control subjects, patients with tachyarrhythmia had significantly lower global LS. Improvement in LVEF within 6 months after treatment of index arrhythmia was observed in 41 patients, and LVEF did not improve in 30 patients. In univariate analysis, lower LVEF at baseline (hazard ratio: HR: 0.59 per 1SD, p=0.04) and higher RALSR (HR: 11.2 per 1SD, p <0.001) were associated with no recovery in LVEF during follow-up. In a multivariate logistic regression model, the significant predictor of LV systolic functional recovery was RALSR (HR: 22.9 per 1SD, p=0.001). A RALSR of 0.61 was sensitive (71%) and specific (90%) in differentiating LV systolic functional recovery (area under the curve: 0.88).Conclusions: The RALSR was associated with LV systolic functional recovery. This information might be useful for clinical evaluation and follow-up in patients with reduced LVEF.
(キーワード): tachycardia induced cardiomyopathy / strain imaging / functional recovery
(出版サイトへのリンク): ● Publication site (DOI): 10.1016/j.jcmg.2016.03.019
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 27665160; ● Summary page in Scopus @ Elsevier: 2-s2.0-84994494325

(DOI: 10.1016/j.jcmg.2016.03.019, PubMed: 27665160, Elsevier: Scopus) A Takashima, Shusuke Yagi, Koji Yamaguchi, S Watanabe, N Yamamoto, H Ito, M Kadota, T Hara, H Yamazaki, Takayuki Ise, Kenya Kusunose, Takeshi Tobiume, Hirotsugu Yamada, Takeshi Soeki, Tetsuzo Wakatsuki and Masataka Sata :
Purulent pericarditis accompanying pericardial abscess induced by nocardia in an immunocompromised patient.,
Circulation Journal, Vol.80, No.11, 2409-2411, 2016.

(キーワード): Abscess / Aged, 80 and over / Echocardiography / Female / Humans / Immunocompromised Host / Nocardia / Nocardia Infections / Pericarditis / Pericardium / Tomography, X-Ray Computed
(出版サイトへのリンク): ● Publication site (DOI): 10.1253/circj.CJ-16-0531
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 27628220; ● Summary page in Scopus @ Elsevier: 2-s2.0-84992462594

(DOI: 10.1253/circj.CJ-16-0531, PubMed: 27628220, Elsevier: Scopus) M Kadota, Takayuki Ise, Shusuke Yagi, Takashi Iwase, Masashi Akaike, R Ueno, Y Kawabata, T Hara, K Ogasawara, Mika Bando, S Bando, Tomomi Matsuura, Koji Yamaguchi, Hirotsugu Yamada, Takeshi Soeki, Tetsuzo Wakatsuki and Masataka Sata :
Response prediction and influence of tolvaptan in chronic heart failure patients considering the interaction of the renin-angiotensin-aldosterone system and arginine vasopressin.,
International Heart Journal, Vol.57, No.4, 461-465, 2016.

(要約): The renin-angiotensin-aldosterone system (RAAS) and arginine vasopressin (AVP) regulate body fluids. Although conventional diuretics have been used for treating heart failure, they activate RAAS and exacerbate renal function. Tolvaptan, a newly developed vasopressin-2 receptor antagonist, elicits aquaresis and improves volume overload in heart failure patients, however, the predictors of tolvaptan effectiveness and the influence on the RAAS and renal function according to tolvaptan therapy are not established. We evaluated 26 chronic heart failure patients receiving therapy with 15 mg/day tolvaptan and examined their laboratory and urinary data before and after tolvaptan therapy. A response to tolvaptan was defined as a body weight decrease by more than 2 kg in a week and a urine volume increase by 500 mL/ day compared with that before tolvaptan administration. Body weight, urine volume, and brain natriuretic peptide levels significantly improved (P < 0.05), without any worsening of renal function represented by serum creatinine, sodium, and potassium. Moreover, no significant changes were observed in the plasma renin activity and plasma aldosterone concentration (PAC). In the responder group, urine osmolality before tolvaptan administration was significantly higher (P < 0.05) but declined significantly after tolvaptan administration (P < 0.05). The AVP/PAC ratio before administration was positively correlated with the efficacy of tolvaptan. Tolvaptan treatment could prevent RAAS activation in chronic heart failure patients. Moreover, monitoring the AVP/PAC ratio may be useful in predicting the tolvaptan response.
(キーワード): Adult / Aged / Aged, 80 and over / Antidiuretic Hormone Receptor Antagonists / Arginine Vasopressin / Benzazepines / Body Mass Index / Female / Heart Failure / Humans / Male / Middle Aged / Prospective Studies / Renin-Angiotensin System / Treatment Outcome
(徳島大学機関リポジトリ): ● Metadata: 109694
(出版サイトへのリンク): ● Publication site (DOI): 10.1536/ihj.15-491
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 27357439; ● Summary page in Scopus @ Elsevier: 2-s2.0-84979587993

(徳島大学機関リポジトリ: 109694, DOI: 10.1536/ihj.15-491, PubMed: 27357439, Elsevier: Scopus) Takeshi Soeki, Tomomi Matsuura, Sachiko Bando, Takeshi Tobiume, Etsuko Uematsu, Takayuki Ise, Kenya Kusunose, Koji Yamaguchi, Shusuke Yagi, Daiju Fukuda, Hirotsugu Yamada, Tetsuzo Wakatsuki, Michio Shimabukuro and Masataka Sata :
Relationship between local production of microRNA-328 and atrial substrate remodeling in atrial fibrillation.,
Journal of Cardiology, Vol.68, No.6, 472-477, 2016.

(要約): BACKGROUND: The underlying mechanism of atrial substrate remodeling in atrial fibrillation (AF) remains unknown. In this study, we investigated whether local and systemic levels of microRNA (miR) might be associated with the presence of AF and with left atrial (LA) substrate properties.METHODS: Blood from the periphery, pulmonary vein (PV), and left atrial appendage (LAA) was sampled from 30 patients with AF undergoing PV isolation, and from 10 control subjects with Wolff-Parkinson-White syndrome and without AF. We measured peripheral, PV, and LAA plasma levels of miR-1, -26, -133a, -328, and -590 by reverse transcription-polymerase chain reaction. LA global contact mapping during sinus rhythm was performed before PV isolation.RESULTS: Plasma levels of miR-328 were higher in patients with AF than in control subjects. Plasma miR-328 levels were significantly higher in the LAA than in the periphery and PV in patients with AF, but not in control subjects. Plasma miR-1 levels were also higher in the LAA than in the PV in AF patients. Interestingly, LAA plasma levels of miR-328 showed a positive correlation with the LA voltage zone index (area with voltage <0.5mV divided by total LA surface area) and a weak correlation with LA volume.CONCLUSION: Local production of miR-328 in the left atrium may be involved in the process of atrial remodeling in patients with AF.
(キーワード): Atrial fibrillation / Left atrium / MicroRNA / Remodeling / Substrate
(出版サイトへのリンク): ● Publication site (DOI): 10.1016/j.jjcc.2015.12.007
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 26987792; ● Summary page in Scopus @ Elsevier: 2-s2.0-84960969355

(DOI: 10.1016/j.jjcc.2015.12.007, PubMed: 26987792, Elsevier: Scopus) Toshiyuki Niki, Tetsuzo Wakatsuki, Koji Yamaguchi, Yoshio Taketani, Hiroyasu Oeduka, Kenya Kusunose, Takayuki Ise, Takashi Iwase, Hirotsugu Yamada, Takeshi Soeki and Masataka Sata :
Effects of the addition of eicosapentaenoic acid to strong statin therapy on inflammatory cytokines and coronary plaque components assessed by integrated backscatter intravascular ultrasound.,
Circulation Journal, Vol.80, No.2, 450-460, 2016.

(要約): BACKGROUND: The effects of eicosapentaenoic acid (EPA) on coronary artery disease have been previously reported; however, those of the addition of EPA to strong statins on coronary plaque components and local inflammatory cytokines are not known.METHODSANDRESULTS: A total of 95 patients who had been treated with strong statin for at least 6 months were randomized into 2 groups: an EPA group (additional treatment with EPA at 1,800 mg/day, n=48) or a control group (no additional treatment, n=47), for 6 months. The tissue characteristics of target coronary plaque in each patient were analyzed using IB-IVUS before and after treatment. We also measured plasma levels of inflammatory cytokines sampled in the coronary sinus (CS) and peripheral vein.A significant reduction in lipid volume (18.5±1.3 to 15.0±1.5 mm(3), P=0.007) and a significant increase in fibrous volume (22.9±0.8 to 25.6±1.1 mm(3), P=0.01) were observed in IB-IVUS image analyses in the EPA group, but no significant changes in the plaque components in the control group. CS levels of pentraxin 3 and monocyte chemoattractant protein-1 were lower after than before treatment with EPA (3.3±2.1 to 2.6±1.2 ng/ml, 120.4±26.2 to 110.2±26.8 pg/ml, P=0.015 and P=0.008, respectively); however, there were no significant changes in those inflammatory cytokines between pre- and post-treatment in the control group.CONCLUSIONS: The addition of EPA was associated with reduced lipid volume in coronary plaques and decreased inflammatory cytokines. (Circ J 2016; 80: 450-460).
(キーワード): Coronary plaque / Eicosapentaenoic acid / Inflammatory cytokines / Integrated backscatter intravascular ultrasound / Strong statins
(徳島大学機関リポジトリ): ● Metadata: 109653
(出版サイトへのリンク): ● Publication site (DOI): 10.1253/circj.CJ-15-0813
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 26667367; ● Summary page in Scopus @ Elsevier: 2-s2.0-84955453337

(徳島大学機関リポジトリ: 109653, DOI: 10.1253/circj.CJ-15-0813, PubMed: 26667367, Elsevier: Scopus) Akira Takashima, Shusuke Yagi, Koji Yamaguchi, Eri Takagi, Tamotsu Kanbara, Hirohisa Ogawa, Takayuki Ise, Kenya Kusunose, Takeshi Tobiume, Hirotsugu Yamada, Takeshi Soeki, Tetsuzo Wakatsuki, Tetsuya Kitagawa and Masataka Sata :
Vegetation in the coronary sinus that concealed the presence of a coronary arteriovenous fistula in a patient with infectious endocarditis.,
International Journal of Cardiology, Vol.207, 266-268, 2016.

(キーワード): Coronary sinus / Fistula / Infectious endocarditis / Vegetation
(出版サイトへのリンク): ● Publication site (DOI): 10.1016/j.ijcard.2016.01.057
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 26808990; ● Summary page in Scopus @ Elsevier: 2-s2.0-84958019532

(DOI: 10.1016/j.ijcard.2016.01.057, PubMed: 26808990, Elsevier: Scopus) Shusuke Yagi, Ken-ichi Aihara, Daiju Fukuda, Akira Takashima, Mika Bando, Tomoya Hara, Sachiko Nishimoto, Takayuki Ise, Kenya Kusunose, Koji Yamaguchi, Takeshi Tobiume, Takashi Iwase, Hirotsugu Yamada, Takeshi Soeki, Tetsuzo Wakatsuki, Michio Shimabukuro, Masashi Akaike and Masataka Sata :
Reduced ratio of eicosapentaenoic acid and docosahexaenoic acid to arachidonic acid is associated with early onset of acute coronary syndrome.,
Nutrition Journal, Vol.14, No.1, 111, 2015.

(要約): BACKGROUND: The hospitalization rate for acute coronary syndrome (ACS) for people aged 50 has remained stable over the past decade. Increased serum levels of n-3 polyunsaturated fatty acids (PUFAs), such as eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), are associated with a decreased incidence of cardiovascular events and mortality in older patients; however, it is currently unknown whether reduced serum levels of n-3 PUFAs is also a risk factor for ACS in patients aged 50 years.METHODS AND RESULTS: We retrospectively reviewed 102 (male/ female 73/29) Japanese ACS patients whose serum levels of EPA/arachidonic acid (AA) and DHA/AA were evaluated on admission. The EPA/AA ratio was the lowest in patients aged 50 compared to patients aged 51-74 and 75. Pearson correlation analysis showed that early ACS onset was associated with low EPA/AA and DHA/AA ratios, and multiple regression analysis determined that decreased ratios of EPA/AA and DHA/AA, and male sex, current smoker status, increased body mass index and triglyceride levels, independently correlated with early ACS onset. Conversely, low-density and high-density lipoproteins, glycated hemoglobin, and hypertension did not correlate with early ACS onset. Subgroup analyses of male patients revealed that decreased ratios of EPA/AA and DHA/AA independently correlated with early ACS onset.CONCLUSION: Decreased EPA/AA and DHA/AA ratios may be risk factors for early onset of ACS, suggesting that reduced EPA/AA and DHA/AA may represent targets for preventing ACS in Japanese young people.
(出版サイトへのリンク): ● Publication site (DOI): 10.1186/s12937-015-0102-4
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 26514181; ● Summary page in Scopus @ Elsevier: 2-s2.0-84945959581

(DOI: 10.1186/s12937-015-0102-4, PubMed: 26514181, Elsevier: Scopus) S Bando, Daiju Fukuda, Takeshi Soeki, S Nishimoto, E Uematsu, Tomomi Matsuura, Takayuki Ise, Takeshi Tobiume, Koji Yamaguchi, Shusuke Yagi, Takashi Iwase, Hirotsugu Yamada, Tetsuzo Wakatsuki, Michio Shimabukuro and Masataka Sata :
Expression of NLRP3 in subcutaneous adipose tissue is associated with coronary atherosclerosis.,
Atherosclerosis, Vol.242, No.2, 407-414, 2015.

(要約): ObjectivesThe promotion of adipose tissue inflammation by lifestyle-related diseases such as obesity and diabetes accelerates atherogenesis; however, the underlying mechanisms remain incompletely understood. Nucleotide-binding domain, leucine-rich-containing family, pyrin domain-containing-3 (NLRP3) inflammasome contributes to chronic inflammation in adipose tissue. Here, we investigated the link between NLRP3 expression in subcutaneous adipose tissue (SAT) and the severity of coronary atherosclerosis.Methods and resultsSAT was obtained from 72 patients who underwent heart device implantation and coronary angiography. Expression of NLRP3 inflammasome-related molecules (NLRP3, IL-1 and IL-18) in SAT were evaluated by quantitative RT-PCR. Laboratory markers related to lifestyle-related diseases were measured. Patients with obesity, dyslipidemia (P < 0.05, respectively), diabetes or hyperuricemia (P < 0.01, respectively) had significantly higher expression of NLRP3. Multivariate analysis demonstrated that body mass index and serum level of uric acid were predictors of NLRP3 expression in SAT. The expression of NLRP3 in SAT correlated negatively with serum adiponectin level (r = 0.23, P < 0.05). Patients with coronary artery disease showed higher NLRP3 expression than patients without significant stenosis (P < 0.01). Furthermore, the expression of NLRP3 in SAT correlated positively with the severity of coronary atherosclerosis as determined by Gensini score (r = 0.47, P < 0.0001) or SYNTAX score (r = 0.55, P < 0.0001). Multiple regression analysis revealed that the expression of NLRP3 in SAT remains as an independent predictors for the severity of coronary atherosclerosis.ConclusionsThe expression of NLRP3 in SAT, which is affected by lifestyle-related diseases, is associated with the severity of coronary atherosclerosis. Our results suggest that NLRP3 inflammasome in SAT may have a role in atherogenesis.
(キーワード): Atherosclerosis / Adipose tissue / Inflammation / NLRP3 inflammasome / Lifestyle-related disease
(徳島大学機関リポジトリ): ● Metadata: 109532
(出版サイトへのリンク): ● Publication site (DOI): 10.1016/j.atherosclerosis.2015.07.043
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 26282945; ● Search Scopus @ Elsevier (PMID): 26282945; ● Search Scopus @ Elsevier (DOI): 10.1016/j.atherosclerosis.2015.07.043

(徳島大学機関リポジトリ: 109532, DOI: 10.1016/j.atherosclerosis.2015.07.043, PubMed: 26282945) Shusuke Yagi, Ken-ichi Aihara, Masashi Akaike, Daiju Fukuda, HM Salim, Masayoshi Ishida, Tomomi Matsuura, Takayuki Ise, Koji Yamaguchi, Takashi Iwase, Hirotsugu Yamada, Takeshi Soeki, Tetsuzo Wakatsuki, Michio Shimabukuro, Toshio Matsumoto and Masataka Sata :
Predictive factors for efficacy of dipeptidyl peptidase-4 inhibitors in patients with type 2 diabetes mellitus.,
Diabetes & Metabolism Journal, Vol.39, No.4, 342-347, 2015.

(要約): BACKGROUND: Predictive factors for the efficacy of dipeptidyl peptidase-4 (DPP-4) inhibitors for lowering glycosylated hemoglobin (HbA1c) remain unclear in patients with type 2 diabetes mellitus. The aim of this study is therefore to clarify predictive factors of the efficacy of DPP-4 inhibitors for lowering HbA1c after 12 months of treatment.METHODS: A total of 191 consecutive type 2 diabetic patients (male sex 55%, mean age, 68.3±35.8 years), who had been treated with DPP-4 inhibitors for 12 months, were enrolled in this study and evaluated retrospectively.RESULTS: After 12 months of DPP-4 inhibitor treatment, random blood glucose level, and HbA1c level, decreased from 167±63 to 151±49 mg/dL (P<0.01), and from 7.5%±1.3% to 6.9%±0.9% (P<0.01) respectively, without severe side effects. Multiple regression analysis showed that predictors of DPP-4 inhibitor treatment efficacy in lowering HbA1c level after 12 months were a decrease in HbA1c level after 3 months of treatment, a high baseline HbA1c level, a low baseline body mass index, and the absence of coronary artery disease.CONCLUSION: Most suitable candidates for treatment with DPP-4 inhibitors are diabetics who are not obese and do not have coronary artery disease. In addition, long-term efficacy of DPP-4 inhibitors can be predicted by decrement of HbA1c after 3 months of treatment.
(キーワード): Coronary artery disease / 糖尿病 (diabetes mellitus) / Dipeptidyl-peptidase IV inhibitors / Obese / Predictive factors
(出版サイトへのリンク): ● Publication site (DOI): 10.4093/dmj.2015.39.4.342
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 26301197; ● Summary page in Scopus @ Elsevier: 2-s2.0-84939780057

(DOI: 10.4093/dmj.2015.39.4.342, PubMed: 26301197, Elsevier: Scopus) Kenya Kusunose, Hirotsugu Yamada, Junko Hotsuchi, Mika Bando, Susumu Nishio, Yukina Hirata, Takayuki Ise, Koji Yamaguchi, Shusuke Yagi, Takeshi Soeki, Tetsuzo Wakatsuki, Jun Kishi and Masataka Sata :
Prediction of Future Overt Pulmonary Hypertension by 6-Min Walk Stress Echocardiography in Patients With Connective Tissue Disease.,
Journal of the American College of Cardiology, Vol.66, No.4, 376-384, 2015.

(要約): BACKGROUND: Early detection of pulmonary hypertension (PH) in connective tissue disease (CTD) is crucial to ensuring that patients receive timely treatment for this progressive disease. Exercise stress tests have been used to screen patients in an attempt to identify early-stage PH. Recent studies have described abnormal mean pulmonary artery pressure (mPAP)-cardiac output (Q) responses as having the potential to assess the disease state.OBJECTIVES: This study hypothesized that pulmonary circulation pressure-flow relationships obtained by 6-min walk (6MW) stress echocardiography would better delineate differential progression of PH and predict development of PH during follow-up.METHODS: We prospectively performed 6MW stress echocardiographic studies in 78 CTD patients (age 58 ± 12 years; 9% male) at baseline and follow-up. All patients underwent yearly echocardiographic follow-up studies for up to 5 years.RESULTS: During a median period of 32 months (range: 15 to 62 months), 16 patients reached the clinical endpoint of development of PH and none died during follow-up. PH was confirmed by right heart catheterization in all 16 patients (mPAP 25 mm Hg and pulmonary capillary wedge pressure 15 mm Hg). In a Cox proportional-hazards survival model, 6MW distance (hazard ratio [HR]: 0.99; p = 0.010), early diastolic tricuspid annulus motion velocity (HR: 0.79; p = 0.025), and mPAP/Q by 6MW stress (HR: 1.10; p = 0.005) were associated with development of PH. In sequential Cox models, a model on the basis of 6MW distance (chi-square, 6.6) was improved by mPAP/Q (chi-square: 14.4; p = 0.019). Using a receiver-operating characteristic curve, we found that the best cutoff value of mPAP/Q for predicting development of pulmonary hypertension was >3.3 mm Hg/l/min.CONCLUSIONS: The 6MW stress echocardiography noninvasively provides an incremental prognostic value of PH development in CTD. This is a single-center prospective cohort study. Larger multicenter studies are warranted to confirm this result.
(キーワード): lupus erythematosus / mixed connective tissue disease / pulmonary circulation / systemic scleroderma
(出版サイトへのリンク): ● Publication site (DOI): 10.1016/j.jacc.2015.05.032
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 26205595; ● Summary page in Scopus @ Elsevier: 2-s2.0-84937681606

(DOI: 10.1016/j.jacc.2015.05.032, PubMed: 26205595, Elsevier: Scopus) Hiromu Yamazaki, Koji Yamaguchi, Takeshi Soeki, Tetsuzo Wakatsuki, Toshiyuki Niki, Yoshio Taketani, Atsunori Kitaoka, Kenya Kusunose, Takayuki Ise, Takeshi Tobiume, Shusuke Yagi, Takashi Iwase, Hirotsugu Yamada and Masataka Sata :
Impact of indoxyl sulfate, a uremic toxin, on non-culprit coronary plaque composition assessed by integrated backscatter intravascular ultrasound.,
Circulation Journal, Vol.79, No.8, 1773-1779, 2015.

(要約): BACKGROUND: Uremic toxin has emerged as an important determinant of cardiovascular risk. The aim of this study was to examine the relationship between serum uremic toxin and coronary plaque composition on integrated backscatter intravascular ultrasound (IB-IVUS).MethodsandResults:IB-IVUS was performed in 47 patients with planned treatment for angina pectoris. Non-culprit intermediate plaque analyzed in this study had to be >5 mm apart from the intervention site. 3-D IB-IVUS analysis was performed to determine percent lipid volume (LV) and fibrous volume (FV). We also measured serum uremic toxins (indoxyl sulfate [IS], asymmetric dimethylarginine [ADMA], and p-cresol [PC]). Glomerular filtration rate correlated with IS (r=-0.329, P=0.04), but did not correlate with ADMA or PC. Percent LV correlated with IS (r=0.365, P=0.02), but did not correlate with ADMA or PC. Percent FV also correlated with IS (r=-0.356, P=0.03), but did not correlate with ADMA or PC. On multivariate regression, only IS was associated with percent LV (r=0.359, P=0.04) and percent FV (r=-0.305, P=0.04) independently of potentially confounding coronary risk factors.CONCLUSIONS: Among the uremic toxins, serum IS might be a novel useful biomarker to detect and monitor lipid-rich coronary plaque on IB imaging. (Circ J 2015; 79: 1773-1779).
(キーワード): Coronary plaque / Indoxyl sulfate / Integrated backscatter intravascular ultrasound
(徳島大学機関リポジトリ): ● Metadata: 109533
(出版サイトへのリンク): ● Publication site (DOI): 10.1253/circj.CJ-15-0019
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 25971408; ● Summary page in Scopus @ Elsevier: 2-s2.0-84937904061

(徳島大学機関リポジトリ: 109533, DOI: 10.1253/circj.CJ-15-0019, PubMed: 25971408, Elsevier: Scopus) Kenya Kusunose, Junko Hotsuchi, Y Takagawa, S Nishio, Takayuki Ise, Takeshi Tobiume, Koji Yamaguchi, Shusuke Yagi, Takashi Iwase, Hirotsugu Yamada, Takeshi Soeki, Tetsuzo Wakatsuki and Masataka Sata :
Serial imaging changes during treatment of immunoglobulin G4-related disease with multiple pseudotumors.,
Circulation, Vol.131, No.21, 1882-1883, 2015.

(キーワード): Aged, 80 and over / Antibodies, Anti-Idiotypic / Arteries / Cardiomegaly / Coronary Aneurysm / Eyelid Diseases / Fluorodeoxyglucose F18 / Humans / Immunoglobulin G / Male / Paraproteinemias / Plasma Cells / Positron-Emission Tomography / Radiopharmaceuticals / Tomography, X-Ray Computed
(出版サイトへのリンク): ● Publication site (DOI): 10.1161/CIRCULATIONAHA.115.015638
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 26015466; ● Summary page in Scopus @ Elsevier: 2-s2.0-84936080389

(DOI: 10.1161/CIRCULATIONAHA.115.015638, PubMed: 26015466, Elsevier: Scopus) Shusuke Yagi, Ken-ichi Aihara, Daiju Fukuda, Akira Takashima, Tomoya Hara, Junko Hotsuchi, Takayuki Ise, Koji Yamaguchi, Takeshi Tobiume, Takashi Iwase, Hirotsugu Yamada, Takeshi Soeki, Tetsuzo Wakatsuki, Michio Shimabukuro, Masashi Akaike and Masataka Sata :
Effects of docosahexaenoic acid on the endothelial function in patients with coronary artery disease.,
Journal of Atherosclerosis and Thrombosis, Vol.22, No.5, 447-454, 2015.

(要約): AIM: The consumption of n-3 polyunsaturated fatty acids (PUFA), including docosahexaenoic acid DHA), reduces the incidence of cardiovascular events, and reduced serum levels of n-3 PUFA may be associated with an increased risk of cardiovascular events. However, controversy remains regarding which components of PUFA are associated with the endothelial function in patients with coronary artery disease (CAD). We therefore examined the associations between the n-3 and n-6 PUFA levels and CAD.METHODS: We retrospectively reviewed 160 consecutive Japanese patients with CAD whose endothelial function was measured according to the percent change in flow-mediated dilation (FMD) and the serum levels of n-3 PUFA, including eicosapentaenoic acid (EPA) and DHA, and n-6 PUFA, including arachidonic acid (AA) and dihomo-gamma-linolenic acid (DHLA).RESULTS: A single regression analysis showed no relationships between the FMD and the serum levels of PUFA, including EPA, DHA, AA and DHLA. In contrast, a multiple regression analysis showed that the DHA level was a positive (P0.01) and age was a negative (P0.001) contributor to an increased FMD; however, sex, body mass index, systolic and diastolic blood pressure, current/past smoking and the levels of HbA1c, triglycerides, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, EPA, AA and DHLA did not significantly affect the outcome.CONCLUSIONS: The serum level of DHA is associated with the endothelial function evaluated according to the FMD in patients with CAD, thus suggesting that a low serum level of DHA may be a predictive biomarker for endothelial dysfunction.
(キーワード): Flow-mediated dilation / n-3 polyunsaturated fatty acids / Docosahexaenoic acid
(出版サイトへのリンク): ● Publication site (DOI): 10.5551/jat.26914
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 25342567; ● CiNii @ 国立情報学研究所 (CRID): 1390282679408260352; ● Summary page in Scopus @ Elsevier: 2-s2.0-84929412906

(DOI: 10.5551/jat.26914, PubMed: 25342567, CiNii: 1390282679408260352, Elsevier: Scopus) S Momomura, Y Seino, Y Kihara, H Adachi, Y Yasumura, H Yokoyama, H Wada, Takayuki Ise, K Tanaka and investigator SAVIOR-C :
Adaptive servo-ventilation therapy for patients with chronic heart failure in a confirmatory, multicenter, randomized, controlled study.,
Circulation Journal, Vol.79, No.5, 981-990, 2015.

(要約): Adaptive servo-ventilation (ASV) therapy is expected to be novel nonpharmacotherapy with hemodynamic effects on patients with chronic heart failure (CHF), but sufficient evidence has not been obtained. A 24-week, open-label, randomized, controlled study was performed to confirm the cardiac function-improving effect of ASV therapy on CHF patients. At 39 institutions, 213 outpatients with CHF, whose left ventricular ejection fraction (LVEF) was <40% and who had mild to severe symptoms [New York Heart Association (NYHA) class: ≥II], were enrolled. After excluding 8 patients, 102 and 103 underwent ASV plus guideline-directed medical therapy (GDMT) [ASV group] and GDMT only [control group], respectively. The primary endpoint was LVEF, and the secondary endpoints were HF deterioration, B-type natriuretic peptide (BNP), and clinical composite response (CCR: NYHA class+HF deterioration). LVEF and BNP improved significantly at completion against the baseline values in the 2 groups. However, no significant difference was found between these groups. HF deterioration tended to be suppressed. The ASV group showed a significant improvement in CCR corroborated by significant improvements in NYHA class and ADL against the control group. Under the present study's conditions, ASV therapy was not superior to GDMT in the cardiac function-improving effect but showed a clinical status-improving effect, thus indicating a given level of clinical benefit.
(キーワード): Aged / Aged, 80 and over / Chronic Disease / Female / Heart Failure / Humans / Male / Middle Aged / Natriuretic Peptide, Brain / Respiration, Artificial / Stroke Volume
(出版サイトへのリンク): ● Publication site (DOI): 10.1253/circj.CJ-15-0221
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 25912560; ● Search Scopus @ Elsevier (PMID): 25912560; ● Search Scopus @ Elsevier (DOI): 10.1253/circj.CJ-15-0221

(DOI: 10.1253/circj.CJ-15-0221, PubMed: 25912560) Takeshi Soeki, Koji Yamaguchi, Toshiyuki Niki, E Uematsu, S Bando, T Matsuura, Takayuki Ise, Kenya Kusunose, Junko Hotsuchi, Takeshi Tobiume, Shusuke Yagi, Daiju Fukuda, Yoshio Taketani, Takashi Iwase, Hirotsugu Yamada, Tetsuzo Wakatsuki, Michio Shimabukuro and Masataka Sata :
Plasma microRNA-100 is associated with coronary plaque vulnerability.,
Circulation Journal, Vol.79, No.2, 413-418, 2015.

(要約): BACKGROUND: Although numerous studies have reported altered plasma levels of various microRNAs (miRNAs) in patients with cardiovascular disease, there are no data on the relationship between plasma miRNAs and vulnerable coronary plaque. In this study, we investigated whether plasma miRNAs might be a sensitive marker of coronary plaque vulnerability.MethodsandResults:Integrated backscatter intravascular ultrasound (IB-IVUS) was performed in 32 consecutive patients with angina pectoris who underwent percutaneous coronary intervention. Three-dimensional analysis of IB-IVUS was performed to determine the percentage of lipid volume (%LV) and fibrous volume (%FV). Circulating miRNAs were measured in EDTA-plasma simultaneously obtained from the aorta and the coronary sinus (CS). Muscle-enriched (miR-133a, miR-208a, miR-499), vascular-enriched (miR-92a, miR-100, miR-126, miR-127, miR-145), and myeloid cell-enriched miRNAs (miR-155, miR-223) were measured. Plasma miR-100 was higher in the CS than in the aorta, but there were no significant differences in the levels of other miRNAs between the aorta and CS. Plasma miR-100 in the aorta was positively correlated with %LV (r=0.48, P<0.01) and negatively correlated with %FV (r=-0.41, P<0.05). Importantly, transcoronary concentration gradient of circulating miR-100 was more strongly correlated with %LV (r=0.53, P<0.01) and %FV (r=-0.56, P<0.01).CONCLUSIONS: miR-100 might be released into the coronary circulation from vulnerable coronary plaques. This study provides insights into the role of miRNAs in coronary atherosclerotic disease. (Circ J 2015; 79: 413-418).
(キーワード): Coronary artery disease / Coronary circulation / Intravascular ultrasound / MicroRNA
(出版サイトへのリンク): ● Publication site (DOI): 10.1253/circj.CJ-14-0958
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 25519160; ● CiNii @ 国立情報学研究所 (CRID): 1390001205108464000; ● Summary page in Scopus @ Elsevier: 2-s2.0-84928251309

(DOI: 10.1253/circj.CJ-14-0958, PubMed: 25519160, CiNii: 1390001205108464000, Elsevier: Scopus) S Kimura, Yuka Ueda, Takayuki Ise, Shusuke Yagi, Takashi Iwase, K Nishikawa, Koji Yamaguchi, Hirotsugu Yamada, Takeshi Soeki, Tetsuzo Wakatsuki, Shinsuke Katoh, Masashi Akaike, Natsuo Yasui and Masataka Sata :
Impact of supervised cardiac rehabilitation on urinary albumin excretion in patients with cardiovascular disease.,
International Heart Journal, Vol.56, No.1, 105-109, 2015.

(要約): Urinary albumin excretion is a predictor of cardiovascular death. Cardiac rehabilitation (CR) with exercise training (ET) has been shown to improve exercise capacity and prognosis in patients with cardiovascular disease (CVD). However, it remains unclear whether CR reduces urinary albumin excretion in CVD patients. We performed a retrospective, observational study using data obtained from 98 male CVD patients without macroalbuminuria and estimated glomerular filtration rate (eGFR) < 30 mL/minute/1.73 m(2) who participated in CR with ET during hospitalization. Twenty-three patients continued supervised ET for 6 months (supervised group) and 75 patients quit supervised ET (non-supervised group). The supervised ET program consisted of 60 minutes of supervised sessions 1-3 times a week and 30-60 minutes of home exercise at least twice a week. Urinary albumin/creatinine ratio (ACR) was significantly decreased in the supervised group at 6 months after enrollment (43 ± 71 mg/g to 17 ± 20 mg/g creatinine, P < 0.05) but not in the non-supervised group. eGFR was unchanged in the supervised group but was significantly decreased in the non-supervised group (72 ± 18 mL/minute/1.73 m(2) to 67 ± 17 mL/minute/1.73 m(2), P < 0.001). The results of multiple regression analysis showed that only supervised ET was an independent contributor to ACR. CR with supervised ET decreased urinary albumin excretion without deterioration of renal function. These findings suggest that continuation of a supervised ET program is associated with reduction in the development of CVD and reduction in cardiovascular morbidity and mortality in CVD patients.
(キーワード): Cardiac rehabilitation / Renal function / Cardiovascular disease
(徳島大学機関リポジトリ): ● Metadata: 109367
(出版サイトへのリンク): ● Publication site (DOI): 10.1536/ihj.14-161
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 25742947; ● Search Scopus @ Elsevier (PMID): 25742947; ● Search Scopus @ Elsevier (DOI): 10.1536/ihj.14-161

(徳島大学機関リポジトリ: 109367, DOI: 10.1536/ihj.14-161, PubMed: 25742947) Shusuke Yagi, A Takashima, M Mitsugi, T Wada, Junko Hotsuchi, Ken-ichi Aihara, T Hara, Masayoshi Ishida, Daiju Fukuda, Takayuki Ise, Koji Yamaguchi, Takeshi Tobiume, Takashi Iwase, Hirotsugu Yamada, Takeshi Soeki, Tetsuzo Wakatsuki, Michio Shimabukuro, Masashi Akaike and Masataka Sata :
Effect of combination tablets containing amlodipine 10 mg and irbesartan 100 mg on blood pressure and cardiovascular risk factors in patients with hypertension.,
Therapeutics and Clinical Risk Management, Vol.11, 83-88, 2015.

(要約): Background: Hypertension is one of the major risk factors for cardiovascular and cerebrovascular disease and mortality. Patients who receive insufficient doses of antihypertensive agents or who are poorly adherent to multidrug treatment regimens often fail to achieve adequate blood pressure (BP) control. The aim of this study was to determine the efficacy of an angiotensin II receptor blocker (ARB) and calcium channel blocker (CCB) combination tablet containing a regular dose of irbesartan (100 mg) and a high dose of amlodipine (10 mg) with regard to lowering BP and other risk factors for cardiovascular disease.Methods: We retrospectively evaluated data from 68 patients with essential hypertension whose treatment regimen was changed either from combination treatment with an independent ARB and a low-dose or regular-dose CCB or from a combination tablet of ARB and a low-dose or regular-dose CCB to a combination tablet containing amlodipine 10 mg and irbesartan 100 mg, because of incomplete BP control. Previous treatments did not include irbesartan as the ARB.Results: The combination tablet decreased systolic and diastolic BP. In addition, it significantly decreased serum uric acid, low-density lipoprotein cholesterol, and increased high-density lipoprotein cholesterol levels, independent of the BP-lowering effect. Treatment with the combination tablet did not affect serum triglycerides, plasma glucose, glycated hemoglobin, serum potassium or creatinine levels, or the urinary albumin excretion rate.Conclusion: The combination tablet containing amlodipine 10 mg and irbesartan 100 mg had a greater BP-lowering effect than an ARB and a low-dose or regular-dose CCB. In addition, the combination tablet had more favorable effects on serum uric acid, low-density lipoprotein cholesterol, and high-density lipoprotein cholesterol levels in patients with hypertension.
(キーワード): blood pressure / combination tablet / uric acid / low-density lipoprotein cholesterol / high-density lipoprotein cholesterol
(出版サイトへのリンク): ● Publication site (DOI): 10.2147/TCRM.S72299
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 25624765; ● Summary page in Scopus @ Elsevier: 2-s2.0-84921260560

(DOI: 10.2147/TCRM.S72299, PubMed: 25624765, Elsevier: Scopus) Shusuke Yagi, T Hara, R Ueno, Ken-ichi Aihara, Daiju Fukuda, A Takashima, Junko Hotsuchi, Takayuki Ise, Koji Yamaguchi, Takeshi Tobiume, Takashi Iwase, Hirotsugu Yamada, Takeshi Soeki, Tetsuzo Wakatsuki, Michio Shimabukuro, Masashi Akaike and Masataka Sata :
Serum concentration of eicosapentaenoic acid is associated with cognitive function in patients with coronary artery disease.,
Nutrition Journal, Vol.13, No.1, 112, 2014.

(要約): BACKGROUND: Recent studies have shown that intake of n-3 polyunsaturated fatty acids (PUFAs) is associated with reduced risk of cognitive impairment and coronary artery disease (CAD); however, it is currently unknown whether reduced serum n-3 PUFA is associated with cognitive impairment in patients with CAD.METHODS: We retrospectively evaluated cognitive function with the mini-mental state examination (MMSE), serum levels of PUFAs (including eicosapentaenoic acid [EPA], docosahexaenoic acid [DHA], dihomogammalinolenic acid [DGLA], and arachidonic acid [AA]), cardiovascular risk factors (hypertension, dyslipidemia, diabetes mellitus, cerebrovascular disease, and history of current/previous smoking), and parameters of cardiac function (left ventricular ejection fraction and brain natriuretic peptide levels) in 146 Japanese CAD patients. The associations between the MMSE scores and the other parameters were evaluated.RESULTS: Pearson correlation analysis showed that EPA (R =0.25, P <0.01), EPA/AA ratio (R =0.22, P =0.01), and left ventricular ejection fraction (R =0.15, P =0.04) were positively associated with MMSE score, and that age (R = -0.20, P <0.01) and brain natriuretic peptide levels (R = -0.28, P <0.01) were inversely associated with MMSE score. Multiple regression analysis showed that age (P <0.05) was negatively associated with MMSE score, while EPA (P <0.01) and EPA/AA ratio (P <0.05) were positively associated with MMSE score; however, sex; body mass index; left ventricular ejection fraction; levels of DHA, AA, and DGLA; DHA/AA ratio; brain natriuretic peptide; and presence of hypertension, dyslipidemia, diabetes mellitus, cerebrovascular disease, and history of current/previous smoking were statistically excluded.CONCLUSIONS: Serum EPA concentration is associated with cognitive function in patients with CAD, suggesting that a low serum EPA level is a risk factor for cognitive impairment independent of cardiac function, including left ventricular ejection fraction. This correlation potentially lends further support to a role of dietary n-3 PUFAs in preventing the cognitive decline in CAD patients.
(キーワード): Aged / Arachidonic Acid / Cognition / Cognition Disorders / Coronary Disease / Eicosapentaenoic Acid / Fatty Acids, Omega-3 / Female / Humans / Japan / Male / Middle Aged / Retrospective Studies / Risk Factors / Stroke Volume
(出版サイトへのリンク): ● Publication site (DOI): 10.1186/1475-2891-13-112
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 25471307; ● Summary page in Scopus @ Elsevier: 2-s2.0-84926465688

(DOI: 10.1186/1475-2891-13-112, PubMed: 25471307, Elsevier: Scopus) Koji Yamaguchi, Tetsuzo Wakatsuki, Takeshi Soeki, Toshiyuki Niki, Yoshio Taketani, Hiroyasu Oeduka, Kenya Kusunose, Takayuki Ise, Takashi Iwase, Hirotsugu Yamada and Masataka Sata :
Effects of telmisartan on inflammatory cytokines and coronary plaque component as assessed on integrated backscatter intravascular ultrasound in hypertensive patients.,
Circulation Journal, Vol.78, No.1, 240-247, 2014.

(要約): Telmisartan has unique pleiotropic effects in addition to renin-angiotensin system (RAS)-inhibition effects. The aim of this study was to evaluate the effects of telmisartan on the coronary plaque component and local inflammatory cytokines. A total of 50 patients with hypertension were randomized to 2 groups: the telmisartan group (additional treatment with telmisartan 80mg/day, n=25) or the control group (additional treatment with other anti-hypertensive drugs except RAS blockers, n=25) for 6 months. Tissue characteristics of target coronary plaque were analyzed using integrated backscatter intravascular ultrasound (IB-IVUS) before and after treatment. Plasma levels of inflammatory cytokines sampled in the coronary sinus (CS) and peripheral vein were also measured. Significant increases in fibrous volume (51.2±10.4 to 58.3±7.7%, P=0.03) and reductions in lipid volume (38.4±12.4 to 32.8±9.7%, P=0.03) were observed on IB in the telmisartan group, while there were no significant changes in the plaque component in the control group. CS levels of inflammatory cytokines (matrix metalloproteinase [MMP]3, tumor necrosis factor-, high-sensitivity C-reactive protein and MMP9) were lower after than before treatment in the only telmisartan group (7.7±6.1 to 5.5±4.9ng/ml, 3.1±1.9 to 2.3±2.0pg/ml, 5.6±6.0 to 2.2±2.4mg/L, 36.1±39.3 to 19.9±27.5ng/ml, P=0.02, P=0.03, P=0.04, P=0.07, respectively). Decreased local inflammatory response and plaque stabilization on IB imaging were observed after 6 months of telmisartan treatment. These findings might be associated with local anti-inflammatory and anti-arteriosclerotic effects of telmisartan.
(キーワード): Coronary plaque / Inflammatory cytokine / Integrated backscatter intravascular ultrasound / Telmisartan
(出版サイトへのリンク): ● Publication site (DOI): 10.1253/circj.CJ-13-0741
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 24189463; ● CiNii @ 国立情報学研究所 (CRID): 1390282680085613824; ● Summary page in Scopus @ Elsevier: 2-s2.0-84891099318

(DOI: 10.1253/circj.CJ-13-0741, PubMed: 24189463, CiNii: 1390282680085613824, Elsevier: Scopus) A Takashima, Takayuki Ise, Shusuke Yagi, Takashi Iwase, S Kimura, Yuka Ueda, K Nishikawa, A Ishii, Toshiyuki Niki, Koji Yamaguchi, Yoshio Taketani, Hirotsugu Yamada, Takeshi Soeki, Tetsuzo Wakatsuki, Shinsuke Katoh, Masashi Akaike and Masataka Sata :
Cardiac rehabilitation reduces serum levels of oxidized low-density lipoprotein.,
Circulation Journal, Vol.78, No.11, 2682-2687, 2014.

(要約): BACKGROUND: Oxidized low-density lipoprotein (oxLDL) levels have been found to play an important role in the progression of atherosclerosis. However, methods for effectively reducing oxLDL levels have not been established. Comprehensive cardiac rehabilitation (CR) with exercise training prevents the progression of atherosclerosis, and might reduce oxLDL levels.MethodsandResults:We measured the serum levels of malondialdehyde-modified LDL (MDA-LDL), a marker of oxLDL, in 136 patients who were enrolled in a 6-month CR program. Peak oxygen consumption (VO2) and MDA-LDL levels were analyzed, before and 6 months after enrolment. In total, 67 patients completed the CR program (CR group) and 69 patients failed to complete the program (non-CR group). Peak VO2increased significantly in the CR group (P<0.01). The levels of MDA-LDL decreased significantly in the CR group (P<0.01) but not in the non-CR group. VO2(peak VO2after CR-peak VO2before CR) was negatively associated with MDA-LDL (MDA-LDL after CR-MDA-LDL before CR) (R(2)=0.11, P=0.01). Multiple regression analysis showed that continuing CR was an independent determining factor for lowering MDA-LDL levels.CONCLUSIONS: CR decreases oxLDL levels in patients with cardiovascular diseases. Moreover, CR may prevent cardiovascular events through an antioxidative effect. (Circ J 2014; 78: 2682-2687).
(キーワード): Cardiac rehabilitation / Lipoproteins / Oxidative stress
(徳島大学機関リポジトリ): ● Metadata: 109368
(出版サイトへのリンク): ● Publication site (DOI): 10.1253/circj.CJ-14-0532
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 25241889; ● Search Scopus @ Elsevier (PMID): 25241889; ● Search Scopus @ Elsevier (DOI): 10.1253/circj.CJ-14-0532

(徳島大学機関リポジトリ: 109368, DOI: 10.1253/circj.CJ-14-0532, PubMed: 25241889) Takeshi Soeki, S Bando, E Uematsu, T Matsuura, Toshiyuki Niki, Takayuki Ise, Kenya Kusunose, Junko Hotsuchi, Yuka Ueda, N Tomita, Koji Yamaguchi, Shusuke Yagi, Daiju Fukuda, Yoshio Taketani, Takashi Iwase, Hirotsugu Yamada, Tetsuzo Wakatsuki, Michio Shimabukuro and Masataka Sata :
Pentraxin 3 is a local inflammatory marker in atrial fibrillation.,
Heart and Vessels, Vol.29, No.5, 653-658, 2014.

(要約): Increasing evidence indicates that inflammation contributes to the pathogenesis of atrial fibrillation (AF). Pentraxin 3 (PTX3) is produced abundantly in local inflammatory lesions while C-reactive protein (CRP) is produced mainly in the liver. In this study, we investigated whether a local level of PTX3 might be a sensitive marker for the local inflammation of AF. Blood from the periphery and left atrial appendage (LAA) was sampled from 23 patients with AF undergoing pulmonary vein isolation, and from 10 control subjects with Wolff-Parkinson-White syndrome. We measured peripheral and LAA plasma concentrations of CRP, interleukin-6 (IL-6), tumor necrosis factor- (TNF-), and PTX3. Plasma PTX3 concentrations in both locations were higher in patients with AF than in control subjects. PTX3 concentrations were significantly higher in the LAA than the periphery in patients with AF (3.7 ± 1.4 vs 3.3 ± 1.2 ng/ml, P < 0.01), but not in control subjects (2.4 ± 0.5 vs 2.4 ± 0.5 ng/ml, not significant). Patients and controls showed no significant differences in CRP, IL-6, or TNF- concentrations between the periphery and LAA. Interestingly, there was a significant positive correlation between LAA plasma concentrations of PTX3 and left atrial volume (r = 0.55, P < 0.01). These data demonstrate that Local PTX3 production in the left atrium might reflect the local inflammation of AF.
(キーワード): Pentraxin 3 / Atrial fibrillation / 炎症 (inflammation)
(出版サイトへのリンク): ● Publication site (DOI): 10.1007/s00380-013-0400-8
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 23979265; ● Summary page in Scopus @ Elsevier: 2-s2.0-84929517476

(DOI: 10.1007/s00380-013-0400-8, PubMed: 23979265, Elsevier: Scopus) Shusuke Yagi, M Fujimura, Masashi Akaike, Ken-ichi Aihara, Takashi Iwase, M Tada, Yuka Ueda, Takayuki Ise, Koji Yamaguchi, Tetsuzo Wakatsuki, Toshio Matsumoto and Masataka Sata :
Increase in serum triglyceride was associated with coronary plaque vulnerability in a patient with rheumatoid arthritis.,
Journal of Cardiology Cases, Vol.10, No.2, 54-57, 2014.

(要約): Rates of morbidity and mortality from cardiovascular disease are high in patients with rheumatoid arthritis (RA); however, the mechanisms and biomarkers that reflect coronary plaque vulnerability have not yet been established. We present a case of acute coronary syndrome (ACS) presumably caused by exacerbation of chronic inflammation of RA, in which an abrupt increase in serum triglyceride was seen on the day of onset of ACS but not during effort angina. This case suggests that RA patients with an abrupt increase in triglyceride need intensive care including anti-platelet and statin therapy for the prevention of coronary plaque rupture.<Learning objective: Triglyceride might be a sensitive biomarker of activated macrophages and plaque vulnerability in patients with RA. RA patients with an abrupt increase in triglyceride might need intensive care including anti-platelet and statin therapy for the prevention of coronary plaque rupture.>
(キーワード): Acute coronary syndrome / Triglyceride / Tumor necrosis factor- / Biomarker
(出版サイトへのリンク): ● Publication site (DOI): 10.1016/j.jccase.2014.04.009
(文献検索サイトへのリンク): ● Summary page in Scopus @ Elsevier: 2-s2.0-84905378195

(DOI: 10.1016/j.jccase.2014.04.009, Elsevier: Scopus) Shusuke Yagi, Ken-ichi Aihara, Takeshi Kondo, Itsuro Endo, Junko Hotsuchi, Takayuki Ise, Takashi Iwase, Masashi Akaike, Toshio Matsumoto and Masataka Sata :
High serum parathyroid hormone and calcium are risk factors for hypertension in Japanese patients.,
Endocrine Journal, Vol.61, No.7, 727-733, 2014.

(要約): Excess parathyroid hormone (PTH), known as primary hyperparathyroidism (pHPT), results in hypercalcemia and bone loss. Recent studies have shown that PTH is associated with the occurrence of hypertension in Western countries; however, controversy remains regarding high serum levels of PTH and calcium as risk factors for hypertension in Japanese patients. We retrospectively enrolled 114 consecutive Japanese patients who visited our hospital for examination and treatment of hypercalcemia and/or hypertension with serum calcium levels ≥ 9.8 mg/dL. To estimate the prevalence of hypertension, the patients were categorized according to calcium levels into hypercalcemic (10.2-13.4 mg/dL) and normocalcemic (9.8-10.1 mg/dL) groups, which were further categorized into high PTH (50-440 pg/mL) and low PTH (8-49 pg/mL) groups. The prevalence of hypertension was higher in patients with hypercalcemia than in patients with normocalcemia in both the high and low PTH groups. The prevalence of hypertension was higher in patients with high serum PTH levels than in patients with low serum PTH levels in both the hypercalcemic and normocalcemic groups. Logistic multiple regression analysis determined that serum calcium (P < 0.05) and PTH (P < 0.01) levels were positive contributors to hypertension. In conclusion, high serum levels of PTH and calcium are risk factors for hypertension in Japanese patients.
(キーワード): parathyroid hormone / カルシウム (calcium) / 高血圧 (hypertension)
(出版サイトへのリンク): ● Publication site (DOI): 10.1507/endocrj.EJ14-0004
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 24849536; ● CiNii @ 国立情報学研究所 (CRID): 1390001206300211712; ● Summary page in Scopus @ Elsevier: 2-s2.0-84905190698

(DOI: 10.1507/endocrj.EJ14-0004, PubMed: 24849536, CiNii: 1390001206300211712, Elsevier: Scopus) Hirotsugu Yamada, Kenya Kusunose, S Nishio, Mika Bando, Junko Hotsuchi, S Hayashi, Takayuki Ise, Shusuke Yagi, Koji Yamaguchi, Takashi Iwase, Takeshi Soeki, Tetsuzo Wakatsuki and Masataka Sata :
Pre-load stress echocardiography for predicting the prognosis in mild heart failure.,
JACC. Cardiovascular Imaging, Vol.7, No.7, 641-649, 2014.

(キーワード): Doppler echocardiography / heart failure / leg-positive pressure / stress echocardiography / survival
(出版サイトへのリンク): ● Publication site (DOI): 10.1016/j.jcmg.2014.04.009
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 24954460; ● Summary page in Scopus @ Elsevier: 2-s2.0-84904576445

(DOI: 10.1016/j.jcmg.2014.04.009, PubMed: 24954460, Elsevier: Scopus) S Bando, Takeshi Soeki, T Matsuura, Toshiyuki Niki, Takayuki Ise, Koji Yamaguchi, Yoshio Taketani, Takashi Iwase, Hirotsugu Yamada, Tetsuzo Wakatsuki, Masashi Akaike, T Aiba, W Shimizu and Masataka Sata :
Congenital long QT syndrome with compound mutations in the KCNH2 gene.,
Heart and Vessels, Vol.29, No.4, 554-559, 2014.

(要約): Congenital long QT syndrome is a genetic disorder encompassing a family of mutations that can lead to aberrant ventricular electrical activity. We report on two brothers with long QT syndrome caused by compound mutations in the KCNH2 gene inherited from parents who had no prolonged QT interval on electrocardiography. The proband had syncope, and his elder brother suffered from ventricular fibrillation. Genetic testing revealed that both brothers had multiple mutations in the KCNH2 gene, including a missense mutation of C1474T (exon 6) as well as a frameshift/nonsense mutation, resulting from the insertion of 25 nucleotides, which caused an altered amino acid sequence beginning at codon 302 and a premature termination codon (i.e., TAG) at codon 339 (exon 4). Family genetic screening found that their father had the same frameshift mutation, and their mother and sister had the same missense mutation, in the KCNH2 gene. However, these other family members were asymptomatic, with normal QT intervals on electrocardiography. These results suggest that compound mutations in the KCNH2 gene inherited independently from the parents made the phenotypes of their sons more severe.
(キーワード): KCNH2 gene / Long QT syndrome / Compound mutation / Missense mutation / Frameshift mutation
(出版サイトへのリンク): ● Publication site (DOI): 10.1007/s00380-013-0406-2
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 24057343; ● Summary page in Scopus @ Elsevier: 2-s2.0-84904036858

(DOI: 10.1007/s00380-013-0406-2, PubMed: 24057343, Elsevier: Scopus) S Hayashi, Hirotsugu Yamada, Mika Bando, Junko Hotsuchi, Takayuki Ise, Koji Yamaguchi, Takashi Iwase, Takeshi Soeki, Tetsuzo Wakatsuki, Toshiaki Tamaki and Masataka Sata :
Augmentation Index does not Reflect the Risk of Coronary Artery Disease in Elderly Patients.,
Circulation Journal, Vol.78, No.5, 1176-1182, 2014.

(要約): BACKGROUND: Augmentation index (AI) has been used as a clinical index of arterial stiffness and has been reported to be an independent predictor of cardiovascular events, but some investigators have reported that AI is not a useful marker to identify coronary artery disease (CAD) in elderly patients. The majority of CAD patients are elderly people, therefore the aim of this study was to examine whether AI is a useful marker to identify the risk of CAD.METHODS AND RESULTS: A total of 120 patients (69±10 years of age; 83 male) who underwent cardiac catheterization for suspected CAD were enrolled. Invasive central blood pressure (BP) was measured using a fluid-filled catheter. Non-invasive AI was calculated by the SphygmoCor (AtCor Medical) system at the end of catheterization. Subjects consisted of 99 patients with CAD and 21 patients without CAD. There was no significant difference in AI between the CAD and the non-CAD groups (24±10 vs. 24±14%). Non-invasive systolic central BP was lower than the invasive systolic central BP (115±18 vs. 130±23 mmHg, P<0.001) in all patients. Non-invasive diastolic central BP was greater than the invasive diastolic central BP (67±10 vs. 63±10 mmHg, P<0.001).CONCLUSIONS: In elderly patients, AI may not be a useful marker to identify CAD
(キーワード): Arterial stiffness / Augmentation index / Central blood pressure / Coronary artery disease
(徳島大学機関リポジトリ): ● Metadata: 106070
(出版サイトへのリンク): ● Publication site (DOI): 10.1253/circj.CJ-13-1422
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 24562676; ● CiNii @ 国立情報学研究所 (CRID): 1390001205107150592; ● Summary page in Scopus @ Elsevier: 2-s2.0-84899659435

(徳島大学機関リポジトリ: 106070, DOI: 10.1253/circj.CJ-13-1422, PubMed: 24562676, CiNii: 1390001205107150592, Elsevier: Scopus) Takayuki Ise, Takashi Iwase, S Masuda, Shusuke Yagi, Masashi Akaike, S Nishio, Toshiyuki Niki, Koji Yamaguchi, Yoshio Taketani, Hirotsugu Yamada, Takeshi Soeki, Tetsuzo Wakatsuki and Masataka Sata :
Acute pulmonary thromboembolism from deep vein thrombosis induced by trauma to the popliteal vein with a tennis racket.,
Journal of Cardiology Cases, Vol.9, No.4, 162-164, 2014.

(要約): Acute pulmonary thromboembolism (PTE) is mainly caused by deep vein thrombosis (DVT) and sometimes leads to a fatal outcome. Few cases of sport-related lower extremity DVT, involving direct external trauma, have been reported. A 58-year-old man, without any risk factors for thromboembolism suffered acute PTE from DVT after playing tennis. A detailed history revealed that he had hit his popliteal vein with each swing of his tennis racket and the site of the trauma, at popliteal fossa, was exactly the same as the site of the DVT formation. Therefore, the cause of DVT was suspected to be the repeated trauma to the popliteal vein. The repeated external trauma to the popliteal vein may have caused vascular endothelial damage, leading to DVT.
(キーワード): Acute pulmonary thromboembolism / Deep vein thrombosis / Trauma
(出版サイトへのリンク): ● Publication site (DOI): 10.1016/j.jccase.2014.01.001
(文献検索サイトへのリンク): ● Summary page in Scopus @ Elsevier: 2-s2.0-84897413698

(DOI: 10.1016/j.jccase.2014.01.001, Elsevier: Scopus) Shusuke Yagi, Kadota Muneyuki, Ken-ichi Aihara, Nishikawa Koji, Hara Tomoya, Takayuki Ise, Yuka Ueda, Takashi Iwase, Masashi Akaike, Michio Shimabukuro, Shinsuke Katoh and Masataka Sata :
Association of lower limb muscle mass and energy expenditure with visceral fat mass in healthy men,
Diabetology & Metabolic Syndrome, Vol.6, No.1, 27, 2014.

(要約): A high-calorie diet and physical inactivity, an imbalance between caloric intake and energy consumption, are major causes of metabolic syndrome (MetS), which manifests as accumulation of visceral fat and insulin resistance. However, the lifestyle-related factors associated with visceral fat mass in healthy men are not fully understood. We evaluated visceral fat area (VFA), skeletal muscle mass, caloric intake, and energy expenditure in 67 healthy male participants (mean age, 36.9 ± 8.8 years; body mass index 23.4 ± 2.5 kg/m2). Multiple regression analysis showed that the total skeletal muscle mass (P < 0.001) were negatively and age (P < 0.001) were positively associated with VFA. Lower limb muscle mass (P < 0.001) was strongly associated with VFA. However, total caloric intake, total energy expenditure, and energy expenditure during exercise were not associated with VFA. Skeletal muscle mass especially lower limb muscle mass negatively contributes to visceral fat mass in healthy men. Therefore, maintaining lower limb muscular fitness through daily activity may be a useful strategy for controlling visceral obesity and metabolic syndrome.
(出版サイトへのリンク): ● Publication site (DOI): 10.1186/1758-5996-6-27
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 24571923; ● Summary page in Scopus @ Elsevier: 2-s2.0-84896075201

(DOI: 10.1186/1758-5996-6-27, PubMed: 24571923, Elsevier: Scopus) Takeshi Soeki, Toshiyuki Niki, E. Uematsu, S. Bando, T. Matsuura, Kenya Kusunose, Takayuki Ise, Yuka Ueda, N. Tomita, Koji Yamaguchi, Kunihiko Koshiba, Shusuke Yagi, Daiju Fukuda, Yoshio Taketani, Takashi Iwase, Hirotsugu Yamada, Tetsuzo Wakatsuki, Masashi Akaike, Michio Shimabukuro, I. Kishimoto, Kenji Kangawa and Masataka Sata :
Ghrelin protects the heart against ischemia-induced arrhythmias by preserving connexin-43 protein.,
Heart and Vessels, Vol.28, No.6, 795-801, 2013.

(要約): Vagal nerve stimulation has been postulated to confer an antifibrillatory effect. We studied whether ghrelin administration would exert an antiarrhythmic effect via modulation of autonomic nerve activity in rats after acute myocardial ischemia (MI). Male Sprague-Dawley rats were exposed to 30 min of ischemia following ligation of the left coronary artery. Animals were then randomized to receive either ghrelin (n = 26) or saline (n = 26) during the period of coronary ligation. Power spectral analysis of heart-rate variability revealed that the administration of ghrelin increased the high-frequency (HF) power and decreased the low-frequency (LF)/HF ratio. Ventricular tachyarrhythmias were less frequent in rats after MI who received ghrelin in comparison with rats that received saline. Immunoblotting and immunohistochemistry revealed that rats given saline alone during MI exhibited a marked reduction in phosphorylated connexin-43 within the left ventricle, whereas those that received ghrelin displayed only minor reductions in comparison with sham-operated rats. These effects of ghrelin were diminished by the coadministration of atropine or the blockade of vagal afferents. These data demonstrate that the beneficial effect of ghrelin might be mediated by modulation of cardiac autonomic nerve activity.
(キーワード): Animals / Anti-Arrhythmia Agents / Atropine / Connexin 43 / Disease Models, Animal / Ghrelin / Heart Rate / Heart Ventricles / Male / Muscarinic Antagonists / Myocardial Ischemia / Phosphorylation / Rats / Rats, Sprague-Dawley / Tachycardia, Ventricular / Time Factors / Vagotomy / Vagus Nerve
(出版サイトへのリンク): ● Publication site (DOI): 10.1007/s00380-013-0333-2
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 23494606; ● Search Scopus @ Elsevier (PMID): 23494606; ● Search Scopus @ Elsevier (DOI): 10.1007/s00380-013-0333-2

(DOI: 10.1007/s00380-013-0333-2, PubMed: 23494606) Shusuke Yagi, Masashi Akaike, Takayuki Ise, Yuka Ueda, Takashi Iwase and Masataka Sata :
Renin-angiotensin-aldosterone system has a pivotal role in cognitive impairment.,
Hypertension Research, Vol.36, No.9, 753-758, 2013.

(要約): Because dementia is associated with both deterioration in the quality of life and poor prognosis, the prevention of cognitive impairment (CI) is a critical problem in public health promotion. Hypertension is a risk factor for the aggravation of CI, and the renin-angiotensin-aldosterone system (RAAS) is a key player in the increased incidence and development of hypertension. Therefore, the RAAS is considered to be a promoting factor for CI development. Conversely, recent studies have shown that lowering blood pressure with RAAS inhibitors decreases the incidence of CI, dementia and cardiovascular disease. Blood-brain barrier-penetrating RAAS inhibitors appear to have advantages in preventing cognitive decline because they can suppress the RAAS in the hippocampus, which has an important role in cognition. Thus, RAAS blockage is a notable strategy for preventing CI.
(キーワード): Angiotensin-Converting Enzyme Inhibitors / Cognition / Cognition Disorders / Humans / Hypertension / Renin-Angiotensin System / Risk Factors
(出版サイトへのリンク): ● Publication site (DOI): 10.1038/hr.2013.51
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 23698805; ● Summary page in Scopus @ Elsevier: 2-s2.0-84883885656

(DOI: 10.1038/hr.2013.51, PubMed: 23698805, Elsevier: Scopus) Sumiko Yoshida, Ken-ichi Aihara, Yasumasa Ikeda, Yuka Sumitomo-Ueda, Ryoko Uemoto, Kazue Ishikawa, Takayuki Ise, Shusuke Yagi, Takashi Iwase, Yasuhiro Mouri, Matomo Sakari, Takahiro Matsumoto, Ken-ichi Takeyama, Masashi Akaike, Mitsuru Matsumoto, Masataka Sata, Kenneth Walsh, Shigeaki Kato and Toshio Matsumoto :
Androgen receptor promotes sex-independent angiogenesis in response to ischemia and is required for activation of vascular endothelial growth factor receptor signaling.,
Circulation, Vol.128, No.1, 60-71, 2013.

(要約): These results document a physiological role of AR in sex-independent angiogenic potency and provide evidence of novel cross-talk between the androgen/AR signaling and VEGF/kinase insert domain protein receptor signaling pathways.
(出版サイトへのリンク): ● Publication site (DOI): 10.1161/CIRCULATIONAHA.113.001533
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 23723256; ● Search Scopus @ Elsevier (PMID): 23723256; ● Search Scopus @ Elsevier (DOI): 10.1161/CIRCULATIONAHA.113.001533

(DOI: 10.1161/CIRCULATIONAHA.113.001533, PubMed: 23723256) Shusuke Yagi, Masashi Akaike, Ken-ichi Aihara, Daiju Fukuda, Masayoshi Ishida, Takayuki Ise, Toshiyuki Niki, Yuka Ueda, Koji Yamaguchi, Takashi Iwase, Yoshio Taketani, Hirotsugu Yamada, Takeshi Soeki, Tetsuzo Wakatsuki, Michio Shimabukuro and Masataka Sata :
Pharmacology of Aldosterone and the Effects of Mineralocorticoid Receptor Blockade on Cardiovascular Systems.,
Acta Cardiologica Sinica, Vol.29, No.3, 201-207, 2013.

(文献検索サイトへのリンク): ● Summary page in Scopus @ Elsevier: 2-s2.0-84878307366

(Elsevier: Scopus) Takayuki Ise, K Fujioka, Takashi Iwase, J. Hotchi, Masashi Akaike and Masataka Sata :
Ulcer-like projection caused by a penetrating branch to the bronchial artery.,
Journal of the American College of Cardiology, Vol.61, No.8, e147-147, 2013.

(キーワード): Aged / Aorta, Thoracic / Back Pain / Bronchial Arteries / Female / Hematoma / Humans / Remission, Spontaneous / Rupture, Spontaneous / Tomography, X-Ray Computed
(出版サイトへのリンク): ● Publication site (DOI): 10.1016/j.jacc.2012.10.047
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 23428223; ● Summary page in Scopus @ Elsevier: 2-s2.0-84874522803

(DOI: 10.1016/j.jacc.2012.10.047, PubMed: 23428223, Elsevier: Scopus) Tomoya Hara, Hirotsugu Yamada, Akira Takashima, Hiromu Yamasaki, Kozue Ogasawara, Sachiko Bando, Takayuki Ise, Toshiyuki Niki, Kenya Kusunose, Yuka Ueda, Noriko Tomita, Koji Yamaguchi, Yoshio Taketani, Takashi Iwase, Takeshi Soeki, Tetsuzo Wakatsuki, Hidehisa Horiguchi, Naomi Sakashita and Masataka Sata :
Constrictive pericarditis with intrapericardial abscess.,
Circulation Journal, Vol.77, No.3, 786-788, 2013.

(キーワード): Abscess / Aged / Autopsy / Fatal Outcome / Heart Diseases / Humans / Male / Methicillin-Resistant Staphylococcus aureus / Pericarditis, Constrictive / Pericardium / Staphylococcal Infections
(出版サイトへのリンク): ● Publication site (DOI): 10.1253/circj.CJ-12-1098
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 23207988; ● Summary page in Scopus @ Elsevier: 2-s2.0-84874412877

(DOI: 10.1253/circj.CJ-12-1098, PubMed: 23207988, Elsevier: Scopus) N. Kawano, Koji Yamaguchi, Toshiyuki Niki, Yamamoto Takashi, Takashi Iwase, Yoshio Taketani, Takayuki Ise, Hirotsugu Yamada, Takeshi Soeki, Tetsuzo Wakatsuki, K Kawano, A. Kakutani and Masataka Sata :
Two cases of acute myocardial infarction during combined chemotherapy in young patients with testicular cancer.,
Journal of Cardiology Cases, Vol.7, No.6, e176-e180, 2013.

(出版サイトへのリンク): ● Publication site (DOI): 10.1016/j.jccase.2013.02.009
(文献検索サイトへのリンク): ● Summary page in Scopus @ Elsevier: 2-s2.0-84877831795

(DOI: 10.1016/j.jccase.2013.02.009, Elsevier: Scopus) 高島啓, 伊勢孝之, 上田由佳, 岩瀬俊, 八木秀介, 前田香代子, 西川幸治, 小笠原梢, 坂東美佳, 坂東左知子, 冨田紀子, 仁木敏之, 發知淳子, 山口浩司, 竹谷善雄, 山田博胤, 添木武, 若槻哲三, 加藤真介, 赤池雅史, 安井夏生, 佐田政隆 :
心臓リハビリテーションは酸化LDLを低下させる,
心臓リハビリテーション, Vol.18, No.1, 130-133, 2013年.

(キーワード): 酸化LDL / 心臓リハビリテーション / 心肺運動負荷試験
(文献検索サイトへのリンク): ● CiNii @ 国立情報学研究所 (CRID): 1520010381154583040

(CiNii: 1520010381154583040) T Hara, Koji Yamaguchi, Takashi Iwase, M Kadota, Mika Bando, K Ogasawara, S Bando, Takayuki Ise, Toshiyuki Niki, Yuka Ueda, N Tomita, Yoshio Taketani, Hirotsugu Yamada, Takeshi Soeki, Tetsuzo Wakatsuki and Masataka Sata :
Eosinophilic Myocarditis due to Churg-Strauss syndrome with markedly elevated Eosinophil Cationic Protein.,
International Heart Journal, Vol.54, No.1, 51-53, 2013.

(要約): A 67-year-old woman with asthma visited our hospital with increasing dyspnea and new-onset paresthesia and purpura in her legs. Physical examination showed a wheeze, pretibial edema, and surrounding purpura. Chest X-rays showed cardiac decompensation and an electrocardiogram revealed a new ST-T change. Laboratory data showed leukocytosis, hypereosinophilia (10,450/μL), troponin T(+), elevated BNP, and markedly elevated eosinophil cationic protein (ECP) (> 150 ng/mL). Echocardiography revealed diffuse left ventricular hypokinesis (ejection fraction 30%) with increased wall thickness. Coronary angiography was normal. Cardiac magnetic resonance imaging implied diffuse myocardial edema and subendocardial late gadolinium enhancement. Skin biopsy of purpura showed superfi cial perivascular dermatitis with remarkable eosinophilic infiltrations. No evidence of drug allergies, parasitic infection, or myeloproliferative disorder was detected. Based on these findings, a diagnosis of eosinophilic myocarditis due to Churg-Strauss syndrome was considered. She was administered prednisolone at a dose of 1 mg/kg, cyclophosphamide, and diuretics. Several markers of eosinophilic myocarditis and heart failure gradually improved, including ECP. She was discharged 30 days later with no cardiac event. Eosinophilic myocarditis is characterized by predominantly eosinophilic infi ltration. Eosinophilic granule proteins, such as ECP and major basic protein, play important roles in the pathogenesis of eosinophilic myocarditis. We experienced a rare case of eosinophilic myocarditis due to Churg-Strauss syndrome. Markedly elevated ECP played an important role in the early diagnosis and subsequent reduction in ECP served as a marker of monitoring. In an asthmatic patient with dyspnea, hypereosinophilia, and vasculitis, Churg-Strauss syndrome with eosinophilic myocarditis should be considered.
(出版サイトへのリンク): ● Publication site (DOI): 10.1536/ihj.54.51
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 23428926; ● Search Scopus @ Elsevier (PMID): 23428926; ● Search Scopus @ Elsevier (DOI): 10.1536/ihj.54.51

(DOI: 10.1536/ihj.54.51, PubMed: 23428926) 坂東美佳, 山田博胤, 西尾進, 玉井利奈, 平田有紀奈, 弘田大智, 中川摩耶, 林修司, 冨田紀子, 發知淳子, 小笠原梢, 高島啓, 山崎宙, 坂東左知子, 伊勢孝之, 仁木敏之, 上田由佳, 山口浩司, 岩瀬俊, 竹谷善雄, 添木武, 若槻哲三, 佐田政隆, 兼松康久, 里見淳一郎, 永廣信治 :
脂質低下療法による頸動脈プラーク安定化の評価:超音波integrated backscatterを用いたカラーマッピングシステムの開発と臨床応用症例報告 (第28回徳島医学会賞受賞論文),
四国医学雑誌, Vol.68, No.3-4, 147-152, 2012年.

(要約): Background : The carotid plaque vulnerability is related to myocardial and cerebral infarction.We intended to develop an imaging system which enables to visualize tissue characteristics in thecarotid plaques based on ultrasound integrated backscatter(IB). And to test its clinical efficacy,effect of the statin therapy on the plaques was evaluated with our software. Methods and Results :Carotid ultrasound examination was performed and ultrasonographic RAW data of the plaqueswere obtained from8patients undergoing carotid artery endarterectomy. Tissue characteristicsin the plaques of resected examples were compared with preoperative ultrasonic images and thetissue IB values corresponding to the specimens were determined for developing our imaging system.Using this system, Color-coded maps of plaques in the three patients were constructed beforeand after lipid lowing therapy. We could demonstrate that lipid fraction in each plaque decreasedand fibrous or calcification fraction increased in the follow-up study. Conclusions : Changes inhistology of carotid plaques by statin could visualized with our imaging system. This techniquemay become a useful tool for the management of atherosclerosis.
(キーワード): IBS (integrated backscatter) / carotid plaque / CEA (carotid endarterectomy)
(徳島大学機関リポジトリ): ● Metadata: 102836
(文献検索サイトへのリンク): ● CiNii @ 国立情報学研究所 (CRID): 1050282812711314944

(徳島大学機関リポジトリ: 102836, CiNii: 1050282812711314944) 吉田守美子, 粟飯原賢一, 上田由佳, 伊勢孝之, 池田康将, 倉橋清衛, 木内美瑞穂, 遠藤逸朗, 藤中雄一, 岩瀬俊, 赤池雅史, 佐田政隆, 松本俊夫 :
ロスバスタチンによる脂質低下作用非依存的な形態的および機能的頸動脈硬化改善作用,
Progress in Medicine, Vol.32, No.2, 315-320, 2012年. Takayuki Ise, Ken-ichi Aihara, Yuka Ueda, Sumiko Yoshida, Yasumasa Ikeda, Shusuke Yagi, Takashi Iwase, Hirotsugu Yamada, Masashi Akaike, Masataka Sata and Toshio Matsumoto :
Plasma heparin cofactor II activity is inversely associated with left atrial volume and diastolic dysfunction in humans with cardiovascular risk factors.,
Hypertension Research, Vol.34, No.2, 225-231, 2010.

(要約): Thrombin has a crucial role in cardiac remodeling through protease-activated receptor-1 activation in cardiac fibroblasts and cardiomyocytes. As heparin cofactor II (HCII) inhibits the action of tissue thrombin in the cardiovascular system, it is possible that HCII counteracts the development of cardiac remodeling. We investigated the relationships between plasma HCII activity and surrogate markers of cardiac geometry, including left atrial volume index (LAVI), relative wall thickness (RWT) and left ventricular mass index, and deceleration time (DcT) and the ratio of peak E velocity to early diastolic mitral annulus velocity (E/e' ratio) as surrogate markers of left ventricular diastolic dysfunction measured using echocardiography in 304 Japanese elderly individuals without systolic heart failure (169 men and 135 women; mean age: 65.4 ± 11.8 years). Mean plasma HCII activity in all participants was 95.8 ± 17.0% and there was no difference between the mean plasma HCII activities in males and females. Multiple regression analysis revealed that there were significant inverse relationships between plasma HCII activity and LAVI (coefficient: -0.2302, P<0.001), between HCII activity and RWT (coefficient: -0.0007, P<0.05), between HCII activity and DcT (coefficient: -0.5189, P<0.05) and between HCII activity and E/e' ratio (coefficient: -0.0558, P<0.01). Plasma HCII activity was independently and inversely associated with the development of cardiac remodeling, including cardiac concentric change, left atrial enlargement and left ventricular diastolic dysfunction. These findings suggest that cardiac tissue thrombin inactivation by HCII is a novel therapeutic target for cardiac remodeling and atherosclerosis.
(キーワード): Aged / Cross-Sectional Studies / Female / Heparin Cofactor II / Humans / Male / Middle Aged / Risk Factors / Ventricular Dysfunction / Ventricular Remodeling
(出版サイトへのリンク): ● Publication site (DOI): 10.1038/hr.2010.211
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 21107326; ● Search Scopus @ Elsevier (PMID): 21107326; ● Search Scopus @ Elsevier (DOI): 10.1038/hr.2010.211

(DOI: 10.1038/hr.2010.211, PubMed: 21107326) 粟飯原賢一, 赤池雅史, 池田康将, 上田由佳, 吉田守美子, 伊勢孝之, 八木秀介, 岩瀬俊, 近藤彰, 田村克也, 松本俊夫 :
アンジオテンシンII受容体拮抗薬バルサルタンのNO bioavailability改善効果に関する臨床的検討,
Progress in Medicine, Vol.29, No.7, 1777-1782, 2009年.

(要約): バルサルタンの降圧作用，動脈硬化抑制作用および糖代謝改善作用に一酸化窒素(NO)のバイオアベイラビリティの改善効果が関与しているか検討した．高血圧治療目的で通院加療中の42例を対象とした．バルサルタン投与にて，BMIやリポプロテイン(a)を含む脂質プロファイルに有意な変化は認めなかったが，収縮期血圧，脈圧，baPWVおよびHbA1cは有意に低下した．投与3ヵ月後には投与前と比較して，NOのバイオアベイラビリティのマーカーである血清硝酸/亜硝酸イオン(NOx)は約1.5倍に増加した．血清NOxの増加が，他の測定因子にどのように影響を与えているか，単変量および多変量解析を用いて解析し，血清NOxの増加量は収縮期血圧の低下と脈圧の減少との間においてそれぞれ有意な相関がみられた．また，HbA1cはバルサルタン投与3ヵ月後に有意に低下していたが，その変化はNOxの増加量と有意な相関がみられた．
(キーワード): Nitrogen Oxides(血液) Glycosylated Hemoglobin A 降圧剤(治療的利用,薬理学) 高血圧(薬物療法) *生物学的利用率動脈硬化症-アテローム性(予防,診断) 経口投与 *一酸化窒素 *Valsartan(治療的利用,薬理学) *Angiotensin II Type 1 Receptor Blockers(治療的利用,薬理学) 脈波伝播速度ヒト中年(45~64) 高齢者(65~79) 男女

MISC

Kenya Kusunose, Hirotsugu Yamada, Yoshihito Saijo, Susumu Nishio, Yukina Hirata, Takayuki Ise, Koji Yamaguchi, Daiju Fukuda, Shusuke Yagi, Takeshi Soeki, Tetsuzo Wakatsuki and Masataka Sata :
Preload Stress Echocardiography for the Assessment of Heart Failure With Preserved Ejection Fraction,
JACC. Cardiovascular Imaging, Vol.15, No.2, 375-378, 2022.

(出版サイトへのリンク): ● Publication site (DOI): 10.1016/j.jcmg.2021.09.005
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 34656477; ● Search Scopus @ Elsevier (PMID): 34656477; ● Search Scopus @ Elsevier (DOI): 10.1016/j.jcmg.2021.09.005

(DOI: 10.1016/j.jcmg.2021.09.005, PubMed: 34656477) Kenya Kusunose, Hirotsugu Yamada, Rino Suzukawa, Yukina Hirata, Masami Yamao, Takayuki Ise, Shusuke Yagi, Masashi Akaike and Masataka Sata :
Effects of Transthoracic Echocardiographic Simulator Training on Performance and Satisfaction in Medical Students.,
Journal of the American Society of Echocardiography, Vol.29, No.4, 375-377, 2016.

(出版サイトへのリンク): ● Publication site (DOI): 10.1016/j.echo.2015.12.002
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 26743736; ● Summary page in Scopus @ Elsevier: 2-s2.0-84960912424

(DOI: 10.1016/j.echo.2015.12.002, PubMed: 26743736, Elsevier: Scopus)

総説・解説

石井亜由美, 西川幸治, 伊勢孝之, 門田宗之, 八木秀介, 岩瀬俊, 木下肇, 阪田美穂, 早渕康信, 北川哲也, 赤池雅史, 加藤真介, 佐田政隆 :
単心室症患児の開心術後にフェイススケールを用いて心臓リハビリテーションを試みた1症例,
心臓, Vol.48, No.2, 181-186, 2016年2月.

(キーワード): 心臓リハビリテーション / 小児 (infant) / フェイススケール

伊勢孝之, 高木恵理, 岩瀬俊, 楠瀬賢也, 山口浩司, 八木秀介, 山田博胤, 添木武, 若槻哲三, 佐田政隆 :
心臓サルコイドーシス再燃に対してメトトレキサートの併用が有効であった1例,
日本内科学会雑誌, Vol.104, No.6, 1175-1179, 2015年.

(要約): 心臓サルコイドーシスの標準的治療はステロイドであるが，ステロイドを投与中であっても再燃を認めることも多く，またステロイドの多岐にわたる副作用も問題となることが多い．症例は70歳代，女性．心臓サルコイドーシスの診断でプレドニンを維持量5 mg/日で加療されていた．定期検査で施行した心電図で陰性T波，前壁心尖部に新規の左室壁運動異常を認めた．FDG-PET，Gaシンチグラフィーで壁運動異常部位に一致して集積を認め，心臓サルコイドーシスの再燃と判断した．本症例では，ステロイドの副作用として糖尿病，肥満，白内障などを認めており，ステロイド増量が躊躇され，メトトレキサートの併用を開始した．メトトレキサート開始後，特に副作用を認めず，心電図ならびに左室壁運動異常の改善が認められた．ステロイド投与で再燃を認める心臓サルコイドーシス症例にはメトトレキサート併用も考慮すべきであると考えられた．
(キーワード): 心臓サルコイドーシス / 再燃 / ステロイド (steroid) / メトトレキサート / 副作用
(出版サイトへのリンク): ● Publication site (DOI): 10.2169/naika.104.1175
(文献検索サイトへのリンク): ● CiNii @ 国立情報学研究所 (CRID): 1390001206449318272; ● Search Scopus @ Elsevier (DOI): 10.2169/naika.104.1175

(DOI: 10.2169/naika.104.1175, CiNii: 1390001206449318272) 今田久美子, 八木秀介, 山口浩司, 若槻哲三, 伊勢孝之, 太田理絵, 門田宗之, 高島啓, 松浦朋美, 飛梅威, 岩瀬俊, 山田博胤, 添木武, 赤池雅史, 佐田政隆 :
心不全を合併した腎血管性高血圧に対する経皮的腎動脈形成術の有効性(第11回若手奨励賞受賞論文),
四国医学雑誌, Vol.70, No.3, 4, 87-92, 2014年8月.

(要約): 【Background】 Percutaneous transluminal renal angioplasty (PTRA) is recommended for patients with heart failure due to renovascular hypertension ; however, the clinical characteristics of the patients and the effects of PTRA on heart failure and cardiorenal function have not been elucidated. 【Methods】 We retrospectively analyzed data for 4 PTRA-treated patients (male/female, 1/3 ; mean age, 70.0±10 years ; mean left ventricular ejection fraction, 51.5±15.2%) with heart failure due to renovascular hypertension and evaluated the effects of PTRA on heart failure and cardiorenal function 6 months after treatment. 【Results】 All patients had pro-arteriosclerotic diseases including diabetes mellitus, essential thrombocythemia, heparin cofactor II deficency, metabolic syndrome, and familial hypercholesterolemia, and 3 patients had ischemic heart disease. No abdominal bruit was heard and mean plasma renin activity was 4.5±3.6 ng/ml/hr, which was not elevated, contrary to expectation. All contralateral kidneys of PTRA were nonfunctioning, suggesting bilateral kidneys were disturbed in all patients. In all patients, PTRA was successfully performed and resolved heart failure. PTRA resulted in decreases in systolic blood pressure from 157±18 to 124±8.6 mmHg, mean serum creatinine from 3.2±2.6 to 2.7±2.2 mg/dl, and mean BNP from 919±998 to 243±291 pg/ml at 6 months after treatment. PTRA did not change left ventricular ejection fraction, a parameter of systolic fraction evaluated by an echocardiogram ; however, PTRA improved E/e', a parameter of left ventricular diastolic fraction, from 16.1±5.2 to 9.7±3.7. None of the patients were hospitalized due to heart failure during the 6-month period after PTRA. 【Conclusions】 Patients with heart failure with cardiovascular risk factors should be screened for renovascular hypertension regardless of abdominal bruit or plasma renin activity. PTRA is effective for resolving heart failure and for improving renal and cardiac diastolic functions in patients with renovascular hypertension complicated with heart failure.
(キーワード): heart failure / cardiac disturbance syndrome / percutaneous transluminal renal angioplasty
(徳島大学機関リポジトリ): ● Metadata: 109759
(文献検索サイトへのリンク): ● CiNii @ 国立情報学研究所 (CRID): 1050001337734629888

(徳島大学機関リポジトリ: 109759, CiNii: 1050001337734629888) 伊勢孝之, 若槻哲三 :
Adaptive Servo Ventilation (ASV) とは?,
人工呼吸, Vol.30, No.1, 28-35, 2013年5月. 伊勢孝之, 佐田政隆 :
専門医トレーニング問題Ⅱ,
循環器専門医, Vol.21, No.1, 132-134, 2013年3月. 伊勢孝之, 佐田政隆 :
心不全予防としての睡眠呼吸障害の診断と介入,
臨床医のための循環器診療, Vol.16, 16-18, 2012年6月.

講演・発表

Kohei Nagano, Tomonori Takahashi, Tetsuzo Wakatsuki, Robert Zheng, Yoshihito Saijyo, Muneyuki Kadota, Yutaka Kawabata, Tomomi Matsuura, Takayuki Ise, Koji Yamaguchi, Shusuke Yagi, Hirotsugu Yamada, Takeshi Soeki and Masataka Sata :
Long-Term Outcome of Stentless Coronary Intervention With Drug-Coated Balloon in Patients With High Bleeding Risk,
AHA2023, Philadelphia, Nov. 2023. N Yamaguchi, Kenya Kusunose, Yukina Hirata, Susumu Nishio, Tomonori Takahashi, Yoshihito Saijo, Muneyuki Kadota, Takayuki Ise, Koji Yamaguchi, Shusuke Yagi, Hirotsugu Yamada, Takeshi Soeki, Tetsuzo Wakatsuki and Masataka Sata :
Improved Pressure-Flow Relationship With Sacubitril/Valsartan: A 6-min Walk Stress Echocardiographic Study,
AHA2023, Philadelphia, Nov. 2023. Tomonori Takahashi, Tetsuzo Wakatsuki, Kenya Kusunose, Takayuki Ise and Masataka Sata :
The aneurysm that vanished into thin air:Spontaneous thrombosis of a giant aneurysm complicated with the coronary to pulmonary artery fistula,
ESC2023, Amsterdam, Aug. 2023. Ryou Bando, Tetsuzo Wakatsuki, Koji Yamaguchi, Yutaka Kawabata, Tomonori Takahashi, Yoshihito Saijyo, Muneyuki Kadota, Tomomi Matsuura, Takayuki Ise, Kenya Kusunose, S Yagi, Hirotsugu Yamada, T Soeki, M Akaike and Masataka Sata :
Two-year outcomes of drug-coated balloon only strategy for de novo lesions in large coronary vessels,
ESC2023, Amsterdam, Aug. 2023. Y Okushi, Kenya Kusunose, Hiromitsu Seno, Tomonori Takahashi, Yoshihito Saijyo, Takayuki Ise, Koji Yamaguchi, Shusuke Yagi, Hirotsugu Yamada, Takeshi Soeki, Tetsuzo Wakatsuki and Masataka Sata :
The Impact of Surveillance of Cancer Therapeutics-Related Cardiac Dysfunction by Periodic Echocardiography,
ASE2022, Seattle, Jun. 2022. Koji Yamaguchi, Tetsuzo Wakatsuki, Y Okushi, Kumiko Suto, Kazuhisa Matsumoto, Tomonori Takahashi, Muneyuki Kadota, Yutaka Kawabata, Tomomi Matsuura, Takayuki Ise, Kenya Kusunose, Shusuke Yagi, Hirotsugu Yamada, Takeshi Soeki and Masataka Sata :
Early and chronic phased local coagulative responses following bioresorbable-polymer drug-eluting stent implantation,
European Heart Journal, Vol.42, No.S1, ehab724.1245, Aug. 2021.

(出版サイトへのリンク): ● Publication site (DOI): 10.1093/eurheartj/ehab724.1245
(文献検索サイトへのリンク): ● Search Scopus @ Elsevier (DOI): 10.1093/eurheartj/ehab724.1245

(DOI: 10.1093/eurheartj/ehab724.1245) Miharu Arase, Kenya Kusunose, Sae Morita, N Yamaguchi, Yukina Hirata, Susumu Nishio, Takayuki Ise, Koji Yamaguchi, Daiju Fukuda, Shusuke Yagi, Hirotsugu Yamada, Takeshi Soeki, Tetsuzo Wakatsuki and Masataka Sata :
Clinical Utility of Noninvasive Assessment of Flow-pressure Relationship in Scleroderma,
American Heart Associeition, Dallas, Nov. 2020. Y Okushi, Kenya Kusunose, Takayuki Ise, Takeshi Tobiume, Koji Yamaguchi, Shusuke Yagi, Daiju Fukuda, Hirotsugu Yamada, Takeshi Soeki, Tetsuzo Wakatsuki and Masataka Sata :
Differences ofCancer Types in Hospital Mortality in Patients With Venous Thromboembolism,
American Heart Association, Dallas, Nov. 2020.

(出版サイトへのリンク): ● Publication site (DOI): 10.1161/circ.142.suppl_3.13145
(文献検索サイトへのリンク): ● Search Scopus @ Elsevier (DOI): 10.1161/circ.142.suppl_3.13145

(DOI: 10.1161/circ.142.suppl_3.13145) Koji Yamaguchi, Tetsuzo Wakatsuki, Tomonori Takahashi, Muneyuki Kadota, Yutaka Kawabata, Tomomi Matsuura, Takayuki Ise, Kenya Kusunose, Takeshi Tobiume, Shusuke Yagi, Hirotsugu Yamada, Takeshi Soeki and Masataka Sata :
Suppressed Local Coagulative Response After Newer-generation Ultrathin Strut SES Implantation Compared to Older-generation SES Implantation,
American Heart Association, Dallas, Nov. 2020.

(出版サイトへのリンク): ● Publication site (DOI): 10.1161/circ.142.suppl_3.12894
(文献検索サイトへのリンク): ● Search Scopus @ Elsevier (DOI): 10.1161/circ.142.suppl_3.12894

(DOI: 10.1161/circ.142.suppl_3.12894) Takeshi Soeki, Kazuhisa Matsumoto, Daiju Fukuda, E Uematsu, Tomomi Matsuura, Takeshi Tobiume, Kenya Kusunose, Takayuki Ise, Koji Yamaguchi, Shusuke Yagi, Hirotsugu Yamada, Tetsuzo Wakatsuki and Masataka Sata :
Toll-like receptor 9 is a novel therapeutic target to prevent atrial fibrillation,
European Heart Journal, Vol.41, No.S2, ehaa946.0463, Aug. 2020.

(出版サイトへのリンク): ● Publication site (DOI): 10.1093/ehjci/ehaa946.0463
(文献検索サイトへのリンク): ● Search Scopus @ Elsevier (DOI): 10.1093/ehjci/ehaa946.0463

(DOI: 10.1093/ehjci/ehaa946.0463) Kenya Kusunose, Nishio Susumu, Hirata Yukina, Takayuki Ise, Koji Yamaguchi, Daiju Fukuda, Shusuke Yagi, Hirotsugu Yamada, Takeshi Soeki, Tetsuzo Wakatsuki and Masataka Sata :
Pulmonary Artery Hypertension Specific Therapy Improves Exercise Tolerance and Outcomes in Exercise-Induced Pulmonary Hypertension,
JACC. Cardiovascular Imaging, Vol.12, No.12, 2576-2579, Dec. 2019.

(キーワード): Adult / Aged / Antihypertensive Agents / Arterial Pressure / Disease Progression / Echocardiography, Stress / Exercise / Exercise Tolerance / Female / Humans / Male / Middle Aged / Progression-Free Survival / Prospective Studies / Pulmonary Arterial Hypertension / Pulmonary Artery / Recovery of Function / Time Factors / Vasodilator Agents / Walk Test
(出版サイトへのリンク): ● Publication site (DOI): 10.1016/j.jcmg.2019.07.002
(文献検索サイトへのリンク): ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 31422131; ● Search Scopus @ Elsevier (PMID): 31422131; ● Search Scopus @ Elsevier (DOI): 10.1016/j.jcmg.2019.07.002

(DOI: 10.1016/j.jcmg.2019.07.002, PubMed: 31422131) Takeshi Soeki, Kazuhisa Matsumoto, Daiju Fukuda, 植松悦子, Tomomi Matsuura, Takeshi Tobiume, Kenya Kusunose, Takayuki Ise, Koji Yamaguchi, Hirotsugu Yamada, Tetsuzo Wakatsuki and Masataka Sata :
Vildagliptin reduces inducitiligy of arterial fibrillation in hypertensive rats complicated with diabetes mellitus,
ESC Congress 2019, Paris, Sep. 2019. Koji Yamaguchi, Tetsuzo Wakatsuki, Rie Ueno, Yutaka Kawabata, Tomomi Matsuura, Takayuki Ise, Kenya Kusunose, Takeshi Tobiume, Shusuke Yagi, Hirotsugu Yamada, Takeshi Soeki and Masataka Sata :
The improvement of chronic local coagulative response according to the progress of drug eluting stent,
ESC Congress 2019, Paris, Sep. 2019. Y Saijo, Kenya Kusunose, Hirotsugu Yamada, Susumu Nishio, Yuta Torii, Y Hirata, Takayuki Ise, Koji Yamaguchi, Shusuke Yagi, Takeshi Soeki, Tetsuzo Wakatsuki and Masataka Sata :
Right Ventricular Contractile Function Predicts Cardiac Events in Passive and Reactive Pulmonary Hypertension,
AHA, Chicago, Nov. 2018. Takeshi Soeki, E Uematsu, Tomomi Matsuura, Takeshi Tobiume, Kenya Kusunose, Takayuki Ise, Koji Yamaguchi, Shusuke Yagi, Daiju Fukuda, Hirotsugu Yamada, Tetsuzo Wakatsuki and Masataka Sata :
C-type natriuretic peptide improves left ventricular diastolic dysfunction and ischemia/reperfusion injury-associated ventricular arrhythmias.,
ESC2018, Munich, Aug. 2018. Hiroyuki Ito, Tetsuzo Wakatsuki, Koji Yamaguchi, Daiju Fukuda, Yutaka Kawabata, Takafumi Todoroki, Tomomi Matsuura, Takayuki Ise, Kenya Kusunose, Takeshi Tobiume, Shusuke Yagi, Hirotsugu Yamada, Takeshi Soeki and Masataka Sata :
Growth of vasa vasorum is associated with local inflammation around coronary plaque in fresh cadavers,
ESC2018, Munich, Aug. 2018. Maimaituxun Gulinu, Michio Shimabukuro, Daiju Fukuda, Shusuke Yagi, Hirata Yukina, Takashi Iwase, Tomomi Matsuura, Takayuki Ise, Kenya Kusunose, Takeshi Tobiume, Koji Yamaguchi, Hirotsugu Yamada, Takeshi Soeki, Tetsuzo Wakatsuki and Masataka Sata :
Gender disparities of distribution of epicardial adipose tissue and its impact on coronary artery disease,
ESC2018, Munich, Aug. 2018. Takeshi Soeki, Tomomi Matsuura, E Uematsu, Takeshi Tobiume, Kenya Kusunose, Takayuki Ise, Koji Yamaguchi, Shusuke Yagi, Daiju Fukuda, Hirotsugu Yamada, Tetsuzo Wakatsuki and Masataka Sata :
Epicardial Adipose Tissue Produces Proinflammatory Cytokines and Influences the Pathogenesis of Atrial Fibrillation,
AHA Scientific Sessions2017, California, America, Nov. 2017. Maimaituxun. Gulinu, Michio Shimabukuro, Y Hirata, Takashi Iwase, S Takao, Tomomi Matsuura, Takayuki Ise, Kenya Kusunose, Takeshi Tobiume, Koji Yamaguchi, Shusuke Yagi, Daiju Fukuda, Hirotsugu Yamada, Takeshi Soeki, Tetsuzo Wakatsuki, M Harada and Masataka Sata :
Local Epicardial Adipose Tissue Thickness in Left Anterior Descending Artery Provides a New Prediction Model for Coronary Artery Disease,
AHA Scientific Sessions2017, California, America, Nov. 2017. Kenya Kusunose, Hirotsugu Yamada, S Nishio, Y Torii, Yukina Hirata, H Seno, Y Saijo, Takayuki Ise, Koji Yamaguchi, Shusuke Yagi, Takeshi Soeki, Tetsuzo Wakatsuki and Masataka Sata :
Echocardiography Predicts Outcomes in Patients With Preserved Ejection Fraction and Low Gradient Aortic Stenosis,
AHA Scientific Sessions2017, California, America, Nov. 2017. Takeshi Soeki, Tomomi Matsuura, Daiju Fukuda, Etsuko Uematsu, Takeshi Tobiume, T Hara, Kenya Kusunose, Takayuki Ise, Koji Yamaguchi, Shusuke Yagi, Hirotsugu Yamada, Tetsuzo Wakatsuki and Masataka Sata :
Activated Factor X Signaling Pathway via Protease-Activated Receptor-2 is a Novel Therapeutic Target to Prevent Atrial Fibrillation,
AHA Scientific Sessions2017, California, America, Nov. 2017. Koji Yamaguchi, Tetsuzo Wakatsuki, Yutaka Kawabata, H Ito, Tomomi Matsuura, Takayuki Ise, Kenya Kusunose, Takeshi Tobiume, Shusuke Yagi, Hirotsugu Yamada, Takeshi Soeki and Masataka Sata :
Preserved Endothelial Function and Suppressed Local Coagulative and Inflammatory Response After Biodegradable Polymer SES Implantation Compared to Durable Polymer SES,
AHA Scientific Sessions2017, California, America, Nov. 2017. Susumu Nishio, Kenya Kusunose, Hirotsugu Yamada, Yukina Hirata, H Seno, Y Saijo, Takayuki Ise, Koji Yamaguchi, Shusuke Yagi, Takeshi Soeki, Tetsuzo Wakatsuki and Masataka Sata :
Echocardiographic Epicardial Adipose Tissue Thickness is a Marker for the Detection of Vasospastic Angina,
ASE2017, Baltimore, Jun. 2017. Kenya Kusunose, Hirotsugu Yamada, Susumu Nishio, Y Hirata, Hiromitsu Seno, Y Saijo, Takayuki Ise, Koji Yamaguchi, Shuusuke Yagi, Takeshi Soeki, Tetsuzo Wakatsuki and Masataka Sata :
Right Ventricular Myocardial Strain during Preload Augmentation is Associated with Exercise Capacity,
ASE2017, Baltimore, Jun. 2017. Shusuke Yagi, Takayuki Ise, Masashi Akaike and Masataka Sata :
Adaptive Servo-ventilation Supported Exercise Increases Exercise Capacity in Patients With Severe Heart Failure,
AHA Scientific Sessions 2016, New Orleans, Nov. 2016. Kenya Kusunose, Hirotsugu Yamada, Y Saijo, H Seno, Y Hirata, Y Torii, S Nishio, Takayuki Ise, Koji Yamaguchi, Shusuke Yagi, Takeshi Soeki, Tetsuzo Wakatsuki and Masataka Sata :
Longitudinal Strain Distribution is a Powerful Predictor for Functional Recovery in Patients With Tachycardia-induced Cardiomyopathy,
AHA Scientific Sessions 2016, New Orleans, Nov. 2016. Kenya Kusunose, Hirotsugu Yamada, H Seno, Y Saijo, Takayuki Ise, Takeshi Tobiume, Koji Yamaguchi, Shusuke Yagi, Takeshi Soeki, Tetsuzo Wakatsuki and Masataka Sata :
Longitudinal Strain Distribution is a Powerful Predictor for Functional Recovery in Patients with Tachycardia-induced Cardiomyopathy,
KSC2016(The 60th Annual Scientific Meeting of The Korean Society of Cardiology), Seoul, Sep. 2016. Takeshi Soeki, Tomomi Matsuura, E Uematsu, S Bando, Takeshi Tobiume, Kenya Kusunose, Takayuki Ise, Koji Yamaguchi, Shusuke Yagi, Daiju Fukuda, Hirotsugu Yamada, Tetsuzo Wakatsuki, Michio Shimabukuro and Masataka Sata :
Increased local production of C-type natriuretic peptide in patients with vasospastic angina,
ESC Congress 2016, Rome, Aug. 2016. Koji Yamaguchi, Tetsuzo Wakatsuki, R Ueno, H Ito, Takayuki Ise, Tomomi Matsuura, Kenya Kusunose, Takeshi Tobiume, Shusuke Yagi, Hirotsugu Yamada, Takeshi Soeki and Masataka Sata :
Paclitaxel eluting balloon angioplasty equals everolimus eluting stent implantation in local coagulative and inflammatory responses in stable angina patients,
ESC Congress 2016, Rome, Aug. 2016. T Matsuura, Takeshi Soeki, E Uematsu, S Bando, Takeshi Tobiume, T Hara, Kenya Kusunose, Takayuki Ise, Koji Yamaguchi, Shusuke Yagi, Daiju Fukuda, Hirotsugu Yamada, Tetsuzo Wakatsuki, Michio Shimabukuro and Masataka Sata :
Oral Direct Factor Xa Inhibitor Prevents Atrial Fibrillation by Inhibiting Inflammation in Rapidly Paced Spontaneously Hypertensive Rats,
ESC Congress 2016, Rome, Aug. 2016. H Seno, Kenya Kusunose, Hirotsugu Yamada, Y Saijo, S Nishio, Y Hirata, Takayuki Ise, Koji Yamaguchi, Shusuke Yagi, Takeshi Soeki, Tetsuzo Wakatsuki and Masataka Sata :
Comparison of Right Ventricular Global Longitudinal Strain Between Vender-Dependent and Vender-Independent Two-Dimensional Speckle Tracking Software,
ACC Scientific Sessions 2016, Chicago, Apr. 2016. S Bando, Takeshi Soeki, Tomomi Matsuura, Takeshi Tobiume, Takayuki Ise, Kenya Kusunose, Koji Yamaguchi, Shusuke Yagi, Hirotsugu Yamada, Tetsuzo Wakatsuki and Masataka Sata :
Atrial Late Potentials and Atrial Substrate Remodeling in Patients With Atrial Fibrillation.,
AHA Scientific Sessions 2015, Orlando, Nov. 2015. Takeshi Soeki, S Bando, Tomomi Matsuura, Takeshi Tobiume, E Uematsu, Kenya Kusunose, Takayuki Ise, Koji Yamaguchi, Shusuke Yagi, Daiju Fukuda, Hirotsugu Yamada, Tetsuzo Wakatsuki, Michio Shimabukuro and Masataka Sata :
Combination Of Clinical, Electrocardiographic and Echocardiographic Parameters Predict the Onset of Atrial Fibrillation.,
AHA Scientific Sessions 2015, Orlando, Nov. 2015. Kenya Kusunose, Hirotsugu Yamada, Mika Bando, S Nishio, Y Hirata, Takayuki Ise, Koji Yamaguchi, Shusuke Yagi, Takeshi Soeki, Tetsuzo Wakatsuki and Masataka Sata :
Pressure-flow Relationship of Pulmonary Circulation Determines Six-minute Walk Distance in Connective Tissue Disease.,
AHA Scientific Sessions 2015, Orlando, Nov. 2015. Koji Yamaguchi, Tetsuzo Wakatsuki, A Takashima, Mika Bando, S Bando, Tomomi Matsuura, Takayuki Ise, Junko Hotsuchi, Takeshi Tobiume, Shusuke Yagi, Takashi Iwase, Hirotsugu Yamada, Takeshi Soeki and Masataka Sata :
Differential response of local coagulation after implantation of new generation drug-eluting stents compared with sirolimus-eluting stent.,
AHA Scientific Sessions 2014, Chicago, Nov. 2014. H Yamazaki, Tetsuzo Wakatsuki, Koji Yamaguchi, K Imada, K Matsumoto, Y Takagawa, E Takagi, Y Saijo, T Hara, Y Saito, Mika Bando, A Takashima, S Bando, Tomomi Matsuura, Takayuki Ise, Junko Hotsuchi, Takeshi Tobiume, Shusuke Yagi, Takashi Iwase, Hirotsugu Yamada, Takeshi Soeki and Masataka Sata :
Differential responses of local coagulation after implantation of second-generation drug-eluting stent compared with first-generation drug-eluting stents.,
AHA Scientific Sessions 2014, Chicago, Nov. 2014. Junko Hotsuchi, Hirotsugu Yamada, Y Saijo, Mika Bando, S Hayashi, S Nishio, M Yamano, Y Torii, Y Hirata, R Amano, Takayuki Ise, Koji Yamaguchi, Takeshi Tobiume, Shusuke Yagi, Takashi Iwase, Takeshi Soeki, Tetsuzo Wakatsuki and Masataka Sata :
Serial Changes of Exercise Stress Echocardiographic Parameters in Patients with Connective Tissue Disease without Overt Pulmonary Hypertension.,
ASE 2014, Portland, Jun. 2014. Y Saijo, Hirotsugu Yamada, Junko Hotsuchi, S Nishio, S Hayashi, Mika Bando, Y Hirata, R Amano, Takayuki Ise, Shusuke Yagi, Koji Yamaguchi, Takashi Iwase, Takeshi Soeki, Tetsuzo Wakatsuki and Masataka Sata :
Right ventricular systolic dysfunction in patients with exercise-induced pulmonary hypertension associated with connective tissue disease.,
ACC 2014, Washington, D.C., Mar. 2014. S Hayashi, Hirotsugu Yamada, Junko Hotsuchi, Mika Bando, Takayuki Ise, Koji Yamaguchi, Takashi Iwase, Takeshi Soeki, Tetsuzo Wakatsuki and Masataka Sata :
Noninvasively Obtained Augmentation Index is Not a Reliable Maker for Vascular Sclerosis in Elderly Subjects.,
American Heart Association AHA 2013, Dallas, Nov. 2013. T Hara, Daiju Fukuda, K Tanaka, Y Higashikuni, Y Hirata, Takayuki Ise, Takeshi Tobiume, Koji Yamaguchi, Shusuke Yagi, Takashi Iwase, Hirotsugu Yamada, Takeshi Soeki, Tetsuzo Wakatsuki, Michio Shimabukuro and Masataka Sata :
Rivaroxaban, A Novel Oral Anticoagulant, Attenuates Plaque Progression in ApoE-Deficient Mice Through the Inhibition of Pro-Inflammatory Activation of Macrophages.,
American Heart Association AHA 2013, Dallas, Nov. 2013. Koji Yamaguchi, Takeshi Soeki, Tetsuzo Wakatsuki, Takayuki Ise, Takeshi Tobiume, Shusuke Yagi, Takashi Iwase, Hirotsugu Yamada and Masataka Sata :
Impact Of Indoxy1 Sulfate, A Uremic Toxin, On Non-culprit Coronary Plaque Composition Assessed By Integrated Backscatter Intravascular Ultrasound In Patients With Coronary Artery Disease.,
American Heart Association AHA 2013, Dallas, Nov. 2013. Koji Yamaguchi, Tetsuzo Wakatsuki, Takayuki Ise, Takeshi Tobiume, Shusuke Yagi, Takashi Iwase, Hirotsugu Yamada, Takeshi Soeki and Masataka Sata :
Decreased Local Hypercoagulation after Implantation of Everolimus-Eluting and Zotarolimus-Eluting Stents Compared with Early-Generation Drug-Eluting Stents in patients with stable angina.,
American Heart Association AHA 2013, Dallas, Nov. 2013. Koji Yamaguchi, Tetsuzo Wakatsuki, Takayuki Ise, Takeshi Tobiume, Shusuke Yagi, Takashi Iwase, Hirotsugu Yamada, Takeshi Soeki and Masataka Sata :
Time-dependent Changes Of Local Vascular Response And Angiographic Peri-stent Contrast Staining Up To Five Years After Zotarolimus-eluting, Sirolimus-eluting, And Bare Metal Stent Implantation.,
American Heart Association AHA 2013, Dallas, Nov. 2013. Takashi Iwase, Shoichiro Takao, Masashi Akaike, Takayuki Ise, Shusuke Yagi, Koji Yamaguchi, Hirotsugu Yamada, Yasuhiko Nishioka, Masafumi Harada and Masataka Sata :
Differentiation of left ventricular systolic dysfunction related to cardiac sarcoidosis and other heart diseases using contrast-enhanced cardiovascular magnetic resonance.,
ESC Congress 2013, Amsterdam, Aug. 2013. Tetsuzo Wakatsuki, Koji Yamaguchi, Toshiyuki Niki, Yoshio Taketani, Takayuki Ise, Takashi Iwase, Hirotsugu Yamada, Takeshi Soeki and Masataka Sata :
The tissue characteristics of coronary plaque with microchannel structure assessed by optical coherence tomography associated with local inflammatory response.,
ESC Congress 2013, Amsterdam, Aug. 2013. K Nishikawa, Shusuke Yagi, Takayuki Ise, Yuka Ueda, Takashi Iwase, Masashi Akaike, Michio Shimabukuro, Shinsuke Katoh and Masataka Sata :
Visceral fat mass is associated with daily physical activity, leg skeletal muscle mass and fiber intake in healthy men.,
ESC Congress 2013, Amsterdam, Aug. 2013. Koji Yamaguchi, Tetsuzo Wakatsuki, Toshiyuki Niki, Yoshio Taketani, Takayuki Ise, Shusuke Yagi, Takashi Iwase, Hirotsugu Yamada, Takeshi Soeki and Masataka Sata :
Differential responses of local coagulation after implantation of everolimus-eluting and zotarolimus-eluting stents compared with early-generation drug-eluting stents in patients with stable angina.,
ESC Congress 2013, Amsterdam, Aug. 2013. S Hayashi, Hirotsugu Yamada, S Nishio, N Tomita, J Hotchi, Mika Bando, Takayuki Ise, Toshiyuki Niki, Koji Yamaguchi, Shusuke Yagi, Yoshio Taketani, Takashi Iwase, Takeshi Soeki, Tetsuzo Wakatsuki and Masataka Sata :
Augmentation Index Measured by Tonometry Significantly Underestimates Atrial Stiffness in Ischemic Heart Disease in Japanese Population.,
第77回日本循環器学会学術集会, Yokohama, Mar. 2013. Sumiko Yoshida, Ken-ichi Aihara, Takayuki Ise, Yuka Ueda, Yasumasa Ikeda, Takashi Iwase, Masashi Akaike, Masataka Sata and Toshio Matsumoto :
Androgen Receptor is Required for Cellular Survival and Angiogenesis in Response to Ischemia via Activation of VEGF Receptor Signaling Pathway Regardless of Sex,
American Heart Association Scientific Session 2012, Nov. 2012. Sumiko Yoshida, Ken-ichi Aihara, Takayuki Ise, Yuka Ueda, Yasumasa Ikeda, Takashi Iwase, Masashi Akaike, Masataka Sata and Toshio Matsumoto :
Eicosapentaenoic acid administration ameliorates cardiac remodeling in humans and protects against Ang II-induced cardiovascular remodeling via attenuation of oxidative stress in mice.,
American Heart Association Scientific Sessions 2012, ロサンゼルス, Nov. 2012. Takayuki Ise, Shusuke Yagi, Takashi Iwase, Masashi Akaike, M Kadota, T Hara, S Bando, Toshiyuki Niki, J Hotchi, N Tomita, Koji Yamaguchi, Yoshio Taketani, Hirotsugu Yamada, Takeshi Soeki, Tetsuzo Wakatsuki and Masataka Sata :
Acute Hemodynamic Effects of Adaptive Servo-Ventilation in Patients with Chronic Left Heart Failure.,
AHA Scientific Sessions 2012, ロサンゼルス, Nov. 2012. Koji Yamaguchi, Tetsuzo Wakatsuki, Takeshi Soeki, Toshiyuki Niki, Yoshio Taketani, H. Oeduka, Mika Bando, K. Ogasawara, S. Bando, J. Hotchi, Takayuki Ise, Takashi Iwase, Hirotsugu Yamada and Masataka Sata :
Telmisartan Reduces Coronary Plaque Vulnerability and Instent-neointimal Proliferation in Hypertensive Patients.,
AHA Scientific Sessions 2012, ロサンゼルス, Nov. 2012. A. Takashima, Takayuki Ise, Masashi Akaike, Yuka Ueda, Takashi Iwase, T. Hara, M. Kadota, R. Ohta, K. Ogasawara, Toshiyuki Niki, J. Hotchi, Koji Yamaguchi, Yoshio Taketani, Hirotsugu Yamada, Takeshi Soeki, Tetsuzo Wakatsuki and Masataka Sata :
Cardiac Rehabilitation Reduces Levels of Oxidized LDL.,
AHA Scientific Sessions 2012, ロサンゼルス, Nov. 2012. S. Bando, Takeshi Soeki, E. Uematsu, T. Matsuura, M. Kadota, T. Hara, R. Ohta, Y. Kawabata, K. Ogasawara, Mika Bando, Toshiyuki Niki, Takayuki Ise, J. Hotchi, N. Tomita, Yuka Ueda, Koji Yamaguchi, Yoshio Taketani, Takashi Iwase, Daiju Fukuda, Hirotsugu Yamada, Tetsuzo Wakatsuki, Michio Shimabukuro and Masataka Sata :
Relationship Between Nlrp3 Inflammasome and Coronary Atherosclerosis.,
AHA Scientific Sessions 2012, ロサンゼルス, Nov. 2012. S. Kimura, Yuka Ueda, Takayuki Ise, Takashi Iwase, K. Maeda, K. Nishikawa, K. Ogasawara, Mika Bando, S. Bando, Toshiyuki Niki, J. Hotchi, Koji Yamaguchi, N. Tomita, Yoshio Taketani, Hirotsugu Yamada, Takeshi Soeki, Tetsuzo Wakatsuki, Masashi Akaike and Masataka Sata :
Effect of Cardiac Rehabilitation with Supervised Exercise Training on Urinary Albumin Excretion in Patients with Cardiovascular Disease.,
AHA Scientific Sessions 2012, ロサンゼルス, Nov. 2012. Toshiyuki Niki, Tetsuzo Wakatsuki, Koji Yamaguchi, Yoshio Taketani, S Bando, Takayuki Ise, Takashi Iwase, Hirotsugu Yamada, Takeshi Soeki and Masataka Sata :
The tissue characteristics of coronary plaque with microchannel structure in patients with Coronary Artery Disease assessed by OCT and IB-IVUS.,
ESC Congress 2012, Munich, Aug. 2012. Mika Bando, Hirotsugu Yamada, N Tomita, S. Nishio, R. Tamai, S. Hayashi, J. Hotchi, Takayuki Ise, Toshiyuki Niki, Koji Yamaguchi, Takashi Iwase, Yoshio Taketani, Takeshi Soeki, Tetsuzo Wakatsuki and Masataka Sata :
Left Ventricular Geometry and Function in Patients with Sigmoid Septum.,
American Society of Echocardiography (ASE) 23rd Annual Scientific Sessions, Maryland, Jun. 2012. S Hayashi, Hirotsugu Yamada, N Tomita, J Hotchi, Mika Bando, S Nishio, R Tamai, M Nakagawa, Takayuki Ise, Toshiyuki Niki, Koji Yamaguchi, Yoshio Taketani, Takashi Iwase, Takeshi Soeki, Tetsuzo Wakatsuki and Masataka Sata :
Differentiation Between Hypertrophic Cardiomyopathy and Hypertensive Heart Disease Using Tricuspid Annular Motion Velocity.,
American Society of Echocardiography (ASE) 23rd Annual Scientific Sessions, Maryland, Jun. 2012. Mika Bando, Hirotsugu Yamada, S Nishio, R Tamai, N. Tomita, S. Hayashi, J. Hotchi, M. Nakagawa, D. Hirota, Y. Hirata, S. Bando, Takayuki Ise, Toshiyuki Niki, Koji Yamaguchi, Takashi Iwase, Yoshio Taketani, Takeshi Soeki, Tetsuzo Wakatsuki and Masataka Sata :
Effect of Statin Therapy on Regression of Carotid Artery Plaque Assessed by High-Resolution Color Mapping Method Based on Integrated Backscatter.,
American Society of Echocardiography (ASE) 23rd Annual Scientific Sessions, Maryland, Jun. 2012. J. Hotchi, Hirotsugu Yamada, S Nishio, Kenya Kusunose, N Tomita, S Hayashi, Mika Bando, R Tamai, M Nakagawa, D Hirota, Y Hirata, K Ogasawara, S Bando, Takayuki Ise, Toshiyuki Niki, Koji Yamaguchi, Yoshio Taketani, Takashi Iwase, Takeshi Soeki, Tetsuzo Wakatsuki and Masataka Sata :
Efficacy of Six-minute Walk Stress Echocardiography for Detection of Pulmonary Arterial Hypertension in Patients With Connective Tissue Disease.,
American Society of Echocardiography (ASE) 23rd Annual Scientific Sessions, Maryland, Jun. 2012. J. Hotchi, Hirotsugu Yamada, R. Tamai, S. Nishio, N. Tomita, S. Hayashi, Mika Bando, S. Bando, Takayuki Ise, Toshiyuki Niki, Koji Yamaguchi, Takashi Iwase, Yoshio Taketani, Takeshi Soeki, Tetsuzo Wakatsuki and Masataka Sata :
Assessment of Tricuspid Annular Motion Velocities in Pulmonary Hypertension of Various Etiologies.,
American Society of Echocardiography (ASE) 23rd Annual Scientific Sessions, Maryland, Jun. 2012. Kenya Kusunose, Hirotsugu Yamada, S. Nishio, N. Tomita, S. Hayashi, J. Hotchi, R. Tamai, D. Hirota, Y. Hirata, Mika Bando, K. Ogasawara, A. Takashima, H. Yamazaki, S. Bando, Takayuki Ise, Toshiyuki Niki, Koji Yamaguchi, Yoshio Taketani, Takashi Iwase, Takeshi Soeki, Tetsuzo Wakatsuki and Masataka Sata :
Single-Beat Assessment of Left Ventricular Systolic and Diastolic Function during Atrial Fibrillation using Myocardial Strain and Strain Rate.,
AHA Scientific Sessions 2011, Orlando, Nov. 2011. Takeshi Soeki, S. Bando, Toshiyuki Niki, H. Yamazaki, A. Takashima, K. Ogasawara, Mika Bando, Takayuki Ise, H. Takeuchi, N. Tomita, Yuka Ueda, Kenya Kusunose, Koji Yamaguchi, Yoshio Taketani, Takashi Iwase, Hirotsugu Yamada, Tetsuzo Wakatsuki and Masataka Sata :
Pentraxin 3 is a Local Inflammatory Maker in Atrial Fibrillation.,
AHA Scientific Sessions 2011, Orlando, Nov. 2011. Takashi Iwase, Shoichiro Takao, Masashi Akaike, Takayuki Ise, Toshiyuki Niki, Kenya Kusunose, Yuka Ueda, N. Tomita, Koji Yamaguchi, Yoshio Taketani, Hirotsugu Yamada, Takeshi Soeki, Ken-ichi Aihara, Tetsuzo Wakatsuki, Masafumi Harada and Masataka Sata :
Detection of Cardiac Involvement in Patients with Sarcoidosis Using Cardiac Magnetic Resonance.,
AHA Scientific Sessions 2011, Orlando, Nov. 2011. Sumiko Yoshida, Ken-ichi Aihara, Takayuki Ise, Yuka Ueda, Yasumasa Ikeda, Takashi Iwase, Masashi Akaike, Masataka Sata and Toshio Matsumoto :
Androgen receptor is essential for cell survival and neovascularization after ischemia.,
American Heart Association Scientific Sessions 2010, Chicago, Nov. 2010. Sumiko Yoshida, Ken-ichi Aihara, Takayuki Ise, Yuka Ueda, Yasumasa Ikeda, Takashi Iwase, Masashi Akaike, Masataka Sata and Toshio Matsumoto :
Androgen receptor participants in ischemia-induced tissue damage and angiogenesis in male mice,
23rd Scientific Meeting of the International Society of Hypertension Vancouver, Vancouver, Sep. 2010. Ken-ichi Aihara, Takayuki Ise, Yuka Ueda, Sumiko Yoshida, Yasumasa Ikeda, Uemoto Ryoko, Shusuke Yagi, Takashi Iwase, Hirata Yoichiro, Masashi Akaike, Masataka Sata and Toshio Matsumoto :
Plasma heparin cofactor II activity is an independent determinant for cardiac remodeling in subjects with cardiovascular risk factors,
20th International Society for Heart Research(ISHR), Kyoto, May 2010. Ken-ichi Aihara, Yuka Ueda, Takayuki Ise, Sumiko Yoshida, Yasumasa Ikeda, Uemoto Ryoko, Shusuke Yagi, Takashi Iwase, Hirata Yoichiro, Masashi Akaike, Masataka Sata and Toshio Matsumoto :
Heparin cofactor II is a novel anticardiac remodeling factor against angiotensin II excess,
20th International Society for Heart Research(ISHR), Kyoto, May 2010. Sumiko Yoshida, Ken-ichi Aihara, Takayuki Ise, Yuka Ueda, Yasumasa Ikeda, Takashi Iwase, Masashi Akaike, Masataka Sata and Toshio Matsumoto :
Exacerbation of cell survival and impaired neovascularization after hindlimb ischemia in male androgen receptor null mice,
20th International Society for Heart Research(ISHR), Kyoto, May 2010. Yuka Ueda, Ken-ichi Aihara, Takayuki Ise, Sumiko Yoshida, Shusuke Yagi, Takashi Iwase, Masashi Akaike, Masataka Sata and Toshio Matsumoto :
Exacerbation of Angiotensin ll-induced Cardiac Remodeling through Enhancement of NADPH oxidase-TGF- 1 Pathway in Heparin Cofactor ll-Deficient Mice,
Scientific Sessions 2009, American Heart Association, Florida, Nov. 2009. Sumiko Yoshida, Ken-ichi Aihara, Takayuki Ise, Yuka Ueda, Shusuke Yagi, Yasumasa Ikeda, Takashi Iwase, Kurahashi Kiyoe, Itsuro Endo, Yuichi Fujinaka, Nishio Susumu, Hirotsugu Yamada, Masashi Akaike, Masataka Sata and Toshio Matsumoto :
Dehydroepiandrosterone sulfate is an endothelial function-independent protective factor against carotid atherosclerosis.,
Scientific Sessions 2009, American Heart Association, Florida, Nov. 2009. Ken-ichi Aihara, Sumiko Yoshida, Takayuki Ise, Sumitomo Yuka, Shusuke Yagi, Takashi Iwase, Kurahashi Kiyoe, Itsuro Endo, Yuichi Fujinaka, Masashi Akaike, Masataka Sata and Toshio Matsumoto :
Increased serum triglyceride but not LDL cholesterol is associated with left ventricular diastolic dysfunction.,
Scientific Sessions 2008, American Heart Association, New Orleans, Nov. 2008. Takayuki Ise, Ken-ichi Aihara, Sumiko Yoshida, Sumitomo Yuka, Shusuke Yagi, Takashi Iwase, Ishikawa Kazue, Masashi Akaike, Masataka Sata and Toshio Matsumoto :
Plasma Heparin Cofactor II Activity Is Inversely Associated with Left Atrial Volume and Left Ventricular Diastolic Dysfunction.,
Scientific Sessions 2008, American Heart Association, New Orleans, Nov. 2008. Sumiko Yoshida, Ken-ichi Aihara, Takayuki Ise, Sumitomo Yuka, Shusuke Yagi, Takashi Iwase, Kurahashi Kiyoe, Itsuro Endo, Yuichi Fujinaka, Masashi Akaike, Masataka Sata and Toshio Matsumoto :
Dehydroepiandrosterone sulfate is an antivascular remodeling factor in elderly individuals.,
Scientific Sessions 2008, American Heart Association, New Orleans, Nov. 2008. Masashi Akaike, Ken-ichi Aihara, Shusuke Yagi, Yasumasa Ikeda, Ishikawa Kazue, Takayuki Ise, Sumiko Yoshida, Sumitomo Yuka, Takashi Iwase and Toshio Matsumoto :
Pitavastatin, an HMG-CoA Reductase Inhibitor, Prevents Glucocorticoid-induced Hypertension through Increased Nitric Oxide Production as a Pleiotropic Effect on Vascular Endothelial Cells,
Hypertension 2008 18th Scientific Meeting of the European Society of Hypertension 22nd Scientific Meeting of the International Society of Hypertension, Berlin, Jun. 2008. Takashi Iwase, Masashi Akaike, Shunji Nakano, Takayuki Ise, Sumiko Yoshida, Sumitomo Yuka, Shusuke Yagi, Ken-ichi Aihara, Natsuo Yasui and Toshio Matsumoto :
Single erythropoietin administration with autologous blood donation - a novel strategy to enhance mobilization of endothelial progenitor cells,
22nd Scientific Meeting of the International Society of Hypertension 2008, Berlin, Germany, Berlin, Jun. 2008. Sumitomo Yuka, Ken-ichi Aihara, Takayuki Ise, Sumiko Yoshida, Shusuke Yagi, Takashi Iwase, Masashi Akaike and Toshio Matsumoto :
Acceleration of angiotensin II-induced cardiac remodeling through enhancement of oxidative stress in heparin cofactor II knockout mice,
22nd Scientific Meeting of the International Society of Hypertension 2008, Berlin, Germany, Berlin, Jun. 2008. Sumiko Yoshida, Ken-ichi Aihara, Takayuki Ise, Sumitomo Yuka, Shusuke Yagi, Takashi Iwase, Masashi Akaike and Toshio Matsumoto :
Dehydroepiandrosterone sulfate regulates carotid blood flow in elderly individuals,
22nd Scientific Meeting of the International Society of Hypertension 2008, Berlin, Germany, Berlin, Jun. 2008. Ken-ichi Aihara, Takayuki Ise, Sumiko Yoshida, Sumitomo Yuka, Shusuke Yagi, Takashi Iwase, Masashi Akaike and Toshio Matsumoto :
Serum Lipid Disorder is Associated with Left Ventricular Diastolic Dysfunction in Elderly Individuals,
22nd Scientific Meeting of the International Society of Hypertension 2008, Berlin, Germany, Berlin, Jun. 2008. Ken-ichi Aihara, Takayuki Ise, Sumiko Yoshida, Sumitomo Yuka, Shusuke Yagi, Takashi Iwase, Masashi Akaike and Toshio Matsumoto :
The active form of vitamin D, 1,25(OH)2D3, prevents vascular remodeling and glucose intolerance in elderly individuals,
22nd Scientific Meeting of the International Society of Hypertension 2008, Berlin, Germany, Berlin, Jun. 2008. R Bando, Koji Yamaguchi, Tetsuzo Wakatsuki, Yutaka Kawabata, Tomonori Takahashi, H Orino, I Yagi, Tomoko Takahashi, Zheng Robert, Yoshihito Saijyo, Tomoya Hara, Muneyuki Kadota, Tomomi Matsuura, Takayuki Ise, Shusuke Yagi, Hirotsugu Yamada, Takeshi Soeki and Masataka Sata :
Predictors of Late Lumen Enlargement after Drug Coated Balloon Angioplasty for de Novo Coronary Lesions,
第88回日本循環器学会学術集会, Mar. 2024. Yutaka Kawabata, Koji Yamaguchi, Tetsuzo Wakatsuki, Tomonori Takahashi, Ryo Bando, Yoshihito Saijyo, 門田宗之, Tomomi Matsuura, Takayuki Ise, Shusuke Yagi, Takeshi Soeki and Masataka Sata :
Microvasculature and Gene Expression in Pericoronary Adipose Tissue According to Coronary Plaque Progression Stage in Fresh Cadavers,
第88回日本循環器学会学術集会, Mar. 2024. Yoshihito Saijyo, Hirotsugu Yamada, 長野絋平, 折野逸人, 八木一成, TAKAHASHI Tomoko, Zengu Robahto, BANDO Ryo, Tomonori Takahashi, Tomoya Hara, Muneyuki Kadota, Yutaka Kawabata, Tomomi Matsuura, Takayuki Ise, Koji Yamaguchi, Shusuke Yagi, Takeshi Soeki, Tetsuzo Wakatsuki and Masataka Sata :
Incremental Value of Relative Apical Sparing Index for Discrimination of Cardiac Amyloidosis Subtypes,
第88回日本循環器学会学術集会, Mar. 2024. M Tserensonom, Shusuke Yagi, Takayuki Ise, Yutaka Kawabata, Muneyuki Kadota, Tomoya Hara, Kenya Kusunose, Koji Yamaguchi, Hirotsugu Yamada, Takeshi Soeki, Tetsuzo Wakatsuki and Masataka Sata :
High Serum lipoprotein (a) level is a risk factor of poor prognosis after transcatheter aortic valve implantation,
第88回日本循環器学会学術集会, Mar. 2024. Ryo Bando, Koji Yamaguchi, Tetsuzo Wakatsuki, Yutaka Kawabata, Tomonori Takahashi, Hayato Orino, Issei Yagi, Tomonori Takahashi, Zheng Robert, Yoshihito Saijyo, Tomoya Hara, Muneyuki Kadota, Tomomi Matsuura, Takayuki Ise, Shusuke Yagi, Hirotsugu Yamada, Takeshi Soeki and Masataka Sata :
Predictors of Late Lumen Enlargement after Drug Coated Balloon Angioplasty for de Novo Coronary Lesions,
第88回日本循環器学会学術集会 JCS2024, Mar. 2024. 川端豊, 山口浩司, 若槻哲三, 髙橋智紀, 坂東遼, 西條良仁, 門田宗之, 松浦朋美, 伊勢孝之, 八木秀介, 添木武, 佐田政隆 :
Microvasculature and Gene Expression in Pericoronary Adipose Tissue According to Coronary Plaque Progression Stage in Fresh Cadavers,
第88回日本循環器学会学術集会, 2024年3月. M Tserensonom, Shusuke Yagi, Takayuki Ise, Yutaka Kawabata, Muneyuki Kadota, Tomoya Hara, Kenya Kusunose, Koji Yamaguchi, Hirotsugu Yamada, Takeshi Soeki, Tetsuzo Wakatsuki and Masataka Sata :
High Serum lipoprotein (a) level is a risk factor of poor prognosis after transcatheter aortic valve implantation,
第88回日本循環器学会学術集会 JCS2024, Mar. 2024. 西川幸治, 伊勢孝之, 石井亜由美, 大南博和, 門田宗之, 八木秀介, 佐田政隆 :
心不全を伴う若年の高度肥満患者に対する心臓リハビリテーションの経験,
日本心臓リハヒリテーション学会第7回四国支部地方会, 2024年3月. 大南博和, 北村彩乃, 増田真志, 伊勢孝之, 八木秀介, 佐田政隆, 竹谷豊 :
心不全マウスに対する高脂肪食と運動の併用効果，優秀演題アワードセッショ,
日本心臓リハヒリテーション学会第7回四国支部地方会, 2024年3月. 八木一成, 西條良仁, 長野絋平, 折野逸人, 吉田直史, 髙橋智子, Robert Zheng, 坂東遼, 髙橋智紀, 原知也, 門田宗之, 川端豊, 松浦朋美, 伊勢孝之, 山口浩司, 八木秀介, 山田博胤, 添木武, 若槻哲三, 佐田政隆 :
ALおよびATTR心アミロイドーシス間のエコー図検査的特徴の相違に関する検討,
第123回日本循環器学会四国支部地方会, 2023年12月. 八木一成, 西條良仁, 長野絋平, 折野逸人, 吉田直史, 髙橋智子, Robert Zheng, 坂東遼, 髙橋智紀, 原知也, 門田宗之, 川端豊, 松浦朋美, 伊勢孝之, 山口浩司, 八木秀介, 山田博胤, 添木武, 若槻哲三, 佐田政隆 :
ALおよびATTR心アミロイドーシス間のエコー図検査的特徴の相違に関する検討,
第123回日本循環器学会四国支部地方会, 2023年10月. 山口夏美, 楠瀬賢也, 門田宗之, 伊勢孝之, 八木秀介, 佐田政隆 :
ARNI投与による慢性心不全患者の安静時および運動時心機能に対する影響:負荷エコーを用いた検討,
第27回日本心不全学会学術集会, 2023年10月. 坂東遼, 山口浩司, 若槻哲三, 伊勢孝之, 川端豊, 髙橋智紀, Zheng Robert, 高橋智子, 吉田直史, 佐田政隆 :
薬剤塗布バルーン治療後に認めた遠隔期血管内腔拡大の長期観察,
第29回日本心血管インターヘンション治療学会(CVIT)中国四国地方会, 2023年9月. 長野紘平, 髙橋智紀, 折野逸人, 大谷啓太, 根岸佑典, 八木一成, 吉田直史, ロバートゼング, 坂東遼, 川端豊, 伊勢孝之, 山口浩司, 若槻哲三, 佐田政隆 :
高血圧リスク患者に対する薬剤コーティングバルーンを用いたstentless PCI 治療の長期成績,
第29回日本心血管インターヘンション治療学会(CVIT)中国四国地方会, 2023年9月. Ryo Bando, Tetsuzo Wakatsuki, Koji Yamaguchi, Yutaka Kawabata, Tomonori Takahashi, Takayuki Ise and Masataka Sata :
Association of coronary plaque characteristics with vasa vasorum and local inflammation of epicardial adipose tissue in fresh cadavers,
CVIT2023, Aug. 2023. Koji Yamaguchi, Tetsuzo Wakatsuki, Ryo Bando, Tomonori Takahashi, Yutaka Kawabata, Takayuki Ise and Masataka Sata :
Limitations of treatment for severely calcified lesions of renal arteries,
CVIT2023, Aug. 2023. 伊勢孝之, 石井亜由美, 西川幸治, 上野理恵, 門田宗之, 八木秀介, 大南博和, 内藤紘一, 竹谷豊, 佐田政隆 :
遠隔伴走型心リハ「リカバル」による新たな在宅心リハの取り組み,
第29回日本心臓リハヒリテーション学会学術集会, 2023年7月. 大南博和, 北村彩乃, 松原未奈, 増田真志, 伊勢孝之, 八木秀介, 佐田政隆, 竹谷豊 :
動物モデルから探る心リハ栄養としての糖・脂質組成の意義,
第29回日本心臓リハヒリテーション学会学術集会, 2023年7月. 石井亜由美, 伊勢孝之, 西川幸治, 大南博和, 門田宗之, 八木秀介, 松浦哲也, 佐田政隆 :
心リハ専従看護師としての働き方,
第29回日本心臓リハヒリテーション学会学術集会, 2023年7月. Zengu Robahto, Muneyuki Kadota, Keita Ohtani, Hayato Orino, Yusuke Negishi, Tomoko Takahashi, Ryo Bando, Hiromitsu Seno, Tomonori Takahashi, Yoshihito Saijyo, Yutaka Kawabata, Tomomi Matsuura, Takayuki Ise, Kenya Kusunose, Koji Yamaguchi, Shusuke Yagi, Hirotsugu Yamada, Takeshi Soeki, Tetsuzo Wakatsuki and Masataka Sata :
A Case of Biopsy-Proven Giant Cell Myocarditis,
第37回日本心エコー図学会学術集会, Apr. 2023. 伊勢孝之, 石井亜由美, 西川幸治, 門田宗之, 八木秀介, 大南博和, 竹谷豊, 佐田政隆 :
遠隔伴走型心臓リハヒリテーション「リカバル」を用いた新たな取り組み,
日本心臓リハヒリテーション学会第6回四国支部地方会, 2023年3月. 宮本亮太, 伊勢孝之, 門田宗之, 八木秀介, 佐村高明, 石井亜由美, 西川幸治, 佐田政隆 :
急性僧帽弁閉鎖不全症に対してImpella 5.5留置下にリハビリを進め，MICS-MVPに繋げた一例,
日本心臓リハヒリテーション学会第6回四国支部地方会, 2023年3月. 西川幸治, 伊勢孝之, 石井亜由美, 大南博和, 門田宗之, 八木秀介, 佐田政隆 :
心不全を伴う若年の高度肥満患者に対する心臓リハヒリテーションの経験,
日本心臓リハヒリテーション学会第6回四国支部地方会, 2023年3月. BANDO Ryo, Tetsuzo Wakatsuki, Koji Yamaguchi, Yutaka Kawabata, Ryota Miyamoto, Zengu Robahto, Tomonori Takahashi, Yoshihito Saijyo, Rie Ueno, Muneyuki Kadota, Tomoya Hara, Tomomi Matsuura, Takayuki Ise, Kenya Kusunose, Shusuke Yagi, Hirotsugu Yamada, Takeshi Soeki, Masashi Akaike and Masataka Sata :
Two-year Outcomes of Drug-coated Balloon-only Strategy for De Novo Lesions in Large Coronary Vessels,
第87回日本循環器学会学術集会, Mar. 2023. Yoshihito Saijyo, Yuichiro Okushi, Kenya Kusunose, Hirotsugu Yamada, Zengu Robahto, Tomonori Takahashi, Hiromitsu Seno, Susumu Nishio, Rie Ueno, Muneyuki Kadota, Tomoya Hara, Yutaka Kawabata, Tomomi Matsuura, Takayuki Ise, Koji Yamaguchi, Shusuke Yagi, Takeshi Soeki, Tetsuzo Wakatsuki and Masataka Sata :
Utility of Periodic Echocardiographic Surveillance for Early Detection of Cardiac Dysfunction from Chemotherapy in Breast Cancer Patients,
第87回日本循環器学会学術集会, Mar. 2023. Yutaka Kawabata, Tetsuzo Wakatsuki, Koji Yamaguchi, BANDO Ryo, Yoshihito Saijyo, Rie Ueno, Muneyuki Kadota, Tomoya Hara, Tomomi Matsuura, Takayuki Ise, Kenya Kusunose, Shusuke Yagi, Hirotsugu Yamada, Takeshi Soeki and Masataka Sata :
The Impact of Coronary Plaque Progression Stage on Coronary Neovascularization Structures in Fresh Cadavers,
第87回日本循環器学会学術集会, Mar. 2023. Takayuki Ise, Shusuke Yagi, Rie Ueno, Muneyuki Kadota, Keita Ohtani, Yusuke Negishi, Ryota Miyamoto, BANDO Ryo, Zengu Robahto, Hiromitsu Seno, Tomonori Takahashi, Yutaka Kawabata, Yoshihito Saijyo, Tomomi Matsuura, Kenya Kusunose, Koji Yamaguchi, Hirotsugu Yamada, Takeshi Soeki, Tetsuzo Wakatsuki and Masataka Sata :
Novel Home-based Cardiac Telerehabilitation System Using a Wearable Device and a Web Application,
第87回日本循環器学会学術集会, Mar. 2023. 大南博和, 北村彩乃, 松原未奈, 増田真志, 伊勢孝之, 八木秀介, 佐田政隆, 竹谷豊 :
動物モデルから探る病期別心リハ栄養の可能性,
第12回日本リハビリテーション栄養学会学術集会, 2023年1月. 北村彩乃, 大南博和, 松原未奈, 増田真志, 伊勢孝之, 八木秀介, 佐田政隆, 竹谷豊 :
高脂肪食が心不全マウスの骨格筋エネルギー代謝に及ぼす影響,
第26回日本病態栄養学会年次学術集会, 2023年1月. 吉田知哉, 伊勢孝之, 宮本亮太, 坂東遼, Robert Zheng, 瀬野弘光, 高橋智紀, 川端豊, 松浦朋美, 西條良仁, 門田宗之, 楠瀬賢也, 添木武, 山口浩司, 八木秀介, 山田博胤, 若槻哲三, 飯間努, 山本浩史, 佐田政隆 :
劇症型心筋炎に対してECPELLA導入で救命しえた症例,
第121回日本循環器学会四国地方会, 2022年12月. 高橋智紀, 楠瀬賢也, Robert Zheng, 瀬野弘光, 西條良仁, 門田宗之, 川端豊, 松浦朋美, 伊勢孝之, 山口浩司, 八木秀介, 山田博胤, 添木武, 若槻哲三, 佐田政隆 :
心房細動患者におけるイソプロテレノール負荷経食堂心エコー図法の有用性,
第121回日本循環器学会四国地方, 2022年12月. 吉田知哉, 若槻哲三, 山木浩二, 西條良仁, 川端豊, 伊勢孝之, 楠瀬賢也, 八木秀介, 山田博胤, 添木武, 佐田政隆 :
冠動脈入口部および鎖骨下動脈に特徴的な血管内超音波所見を認めた高安動脈炎の2例,
第70回日本心臓病学会学術集会, 2022年9月. 伊勢孝之, 内藤紘一, 佐藤聡見, 小野慎太郎, 石井亜由美, 西川幸治, 門田宗之, 八木秀介, 佐田政隆 :
ウェアラブルデバイスとコミュニケーションアプリを用いた遠隔伴走型心リハシステムの開発,
第70回日本心臓病学会学術集会, 2022年9月. 大櫛祐一郎, 楠瀬賢也, 瀬野弘光, 高橋智紀, 西條良仁, 伊勢孝之, 山口浩司, 八木秀介, 山田博胤, 添木武, 若槻哲三, 佐田政隆 :
心エコー検査によるサーベイランスのがん治療関連心筋障害への影響,
第5回日本腫瘍循環器学会学術集会, 2022年9月. 高橋智紀, 山口浩司, 若槻哲三, 宮本亮太, 坂東遼, 川端豊, 伊勢孝之, 佐田政隆 :
腫瘍塞栓が疑われた肺動脈塞栓症に対して下大静脈フィルターを腎静脈上部へ長期留置し得た1例,
第28回日本心血管インターベンション治療学会(CVIT)中国四国地方会, 2022年9月. 坂東遼, 若槻哲三, 川端豊, 山口浩司, 宮本亮太, 高橋智紀, 伊勢孝之, 佐田政隆 :
未個体遺体における冠動脈Lipid-richプラークと外膜vasa vasorumおよび局所心臓周囲脂肪の関連性の検討,
第28回日本心血管インターベンション治療学会(CVIT)中国四国地方会, 2022年9月. 松崎慶仁, 西條良仁, 伊勢孝之, 太田啓太, 折野逸人, 吉田知哉, 根岸佑典, 宮本亮太, 坂東遼, Rovert Zheng, 瀬野弘光, 高橋智紀, 上野理絵, 門田宗之, 原知也, 川端豊, 松浦朋美, 楠瀬賢也, 山口浩司, 八木秀介, 山田博胤, 添木武, 若槻哲三, 佐田政隆 :
急性A型大動脈解離をきたしたMarfan症候群の一例,
第265回徳島県医学学術集会, 2022年7月. 根岸佑典, 門田宗之, 山口浩司, 山田博胤, 折野逸人, 太田啓太, 吉田知哉, 宮本亮太, 坂東遼, Robert Zheng, 瀬野弘光, 高橋智紀, 西條良仁, 上野理絵, 原知也, 川端豊, 松浦朋美, 伊勢孝之, 楠瀬賢也, 八木秀介, 添木武, 若槻哲三, 田蒔昌憲, 佐田政隆 :
腎動脈拡張術により心不全の著名な改善を認めたCardiac Disturbance syndrome の1例,
第265回徳島県医学学術集会, 2022年7月. Koji Yamaguchi, Tetsuzo Wakatsuki, Tomonori Takahashi, Yutaka Kawabata, Takayuki Ise and Masataka Sata :
The impact of polymer duration on local coagulative responses following drug-eluting stent implantation,
第30回日本心血管インターベンション治療学会学術集会, Jul. 2022. 八木秀介, 伊勢孝之, 門田宗之, 川端豊, 原知也, 上野理絵, 西條良仁, 松浦朋美, 楠瀬賢也, 山口浩司, 山田博胤, 添木武, 若槻哲三, 佐田政隆 :
パンデミック下の臨床実習におけるオンライン医学教育の実際と問題点,
第265回徳島県医学学術集会, 2022年6月. 北村彩乃, 大南博和, 増田真志, 奥村仙示, 伊勢孝之, 八木秀介, 福田大受, 山田博胤, 佐田政隆, 竹谷豊 :
運動介入中の脂質摂取の違いが心不全マウスの病態に及ぼす影響,
第28回日本心臓リハビリテーション学会学術集会, 2022年6月. 石井亜由美, 門田宗之, 西川幸治, 大南博和, 伊勢孝之, 八木秀介, 佐田政隆 :
外来心リハ患者に対するアンケート調査から,
2022年6月. 西川幸治, 伊勢孝之, 石井亜由美, 大南博和, 門田宗之, 八木秀介, 佐田政隆 :
コロナ禍における外来心リハ患者の体重変化と健康意識調査,
第28回日本心臓リハビリテーション学術集会, 2022年6月. 伊勢孝之, 内藤紘一, 佐藤聡見, 小野慎太郎, 石井亜由美, 西川幸治, 門田宗之, 八木秀介, 佐田政隆 :
ウェアラブルデバイスとコミュニケーションアプリを用いた遠隔伴走型心リハシステムの開発,
第28回日本心臓リハビリテーション学術集会, 2022年6月. 伊勢孝之, 石井亜由美, 西川幸治, 門田宗之, 八木秀介, 山田博胤, 竹谷豊, 佐田政隆 :
Withコロナに対応した心リハオンライン臨床実習システムの構築,
第28回日本心臓リハビリテーション学術集会, 2022年6月. 高橋里加子, 門田宗之, 伊勢孝之, 西條良仁, 川端豊, 松浦朋美, 楠瀬賢也, 山口浩司, 八木秀介, 山田博胤, 添木武, 若槻哲三, 佐田政隆 :
免疫抑制療法の導入により心機能が劇的に改善した巨細胞性心筋炎の一例,
第120回日本循環器学会中国・四国合同地方会, 2022年5月. 門田宗之, 楠瀬賢也, 八木秀介, 川端豊, 西條良仁, 松浦朋美, 伊勢孝之, 山口浩司, 山田博胤, 添木武, 若槻哲三, 佐田政隆 :
慢性心不全におけるサクビトリル / バルサルタンのナトリウム利尿ペプチドに対する急性反応の検討,
第120回日本循環器学会中国・四国合同地方会, 2022年5月. ツェレンソノムムンフツェツェゲ, 八木秀介, 伊勢孝之, 福田大受, 門田宗之, 川端豊, 楠瀬賢也, 山口浩司, 山田博胤, 添木武, 若槻哲三, 佐田政隆 :
動脈硬化性疾患の高リスク患者において大動脈弁の石灰化と血清リポ蛋白との関連,
第9回日本心血管脳卒中学会学術集会, 2022年4月. Y Okushi, Kenya Kusunose, Zheng Robert, Takayuki Ise, Koji Yamaguchi, Shusuke Yagi, Daiju Fukuda, Hirotsugu Yamada, Takeshi Soeki, Tetsuzo Wakatsuki and Masataka Sata :
Findings from the JROAD-DPC Registry across 6 Studies Conducted in a Year,
第86回日本循環器学術集会, Mar. 2022. Tomonori Takahasi, Kenya Kusunose, Yukina Hirata, Susumu Nisio, Yuichiro Okushi, Hiromitsu Seno, Y Saijo, Muneyuki Kadota, Yutaka Kawabata, Tomomi Matsuura, Takayuki Ise, Koji Yamaguchi, Shusuke Yagi, Daiju Fukuda, Hirotsugu Yamada, Takeshi Soeki, Tetsuzo Wakatsuki and Masataka Sata :
Cardiovascular Risk Factors Associated with Left Ventricular Strain Distribution in Patients without Known Cardiovascular Disease,
第86回日本循環器学会学術集会, Mar. 2022. 北村彩乃, 大南博和, 増田真志, 奥村仙示, 伊勢孝之, 八木秀介, 福田大受, 山田博胤, 佐田政隆, 竹谷豊 :
運動および栄養介入が心不全マウスの病態に及ぼす影響,
日本心臓リハビリテーション学会第 5 回四国支部地方会, 2022年1月. 門田宗之, 石井亜由美, 伊勢孝之, 西川幸治, 八木秀介, 大南博和, 竹谷豊, 佐田政隆 :
当院における末期心不全に患者に対する緩和ケアの取り組み,
日本心臓リハビリテーション学会第5回四国支部地方会, 2022年1月. 石井亜由美, 門田宗之, 西川幸治, 大南博和, 伊勢孝之, 八木秀介, 佐田政隆 :
外来心リハ患者に対するACPアンケート調査から,
日本心臓リハビリテーション学会第5回四国支部地方会, 2022年1月. 西川幸治, 伊勢孝之, 石井亜由美, 大南博和, 門田宗之, 八木秀介, 佐田政隆 :
心リハ研修施設としての活動報告,
日本心臓リハビリテーション学会第5回四国支部地方会, 2022年1月. 伊勢孝之, 石井亜由美, 西川幸治, 門田宗之, 八木秀介, 大南博和, 竹谷豊, 佐田政隆 :
Withコロナに対応したオンライン臨床実習システムの構築,
日本心臓リハビリテーション学会第5回四国支部地方会, 2022年1月. 西條良仁, 佐村高明, 高橋智子, 大櫛祐一郎, 瀬野弘光, 高橋智紀, 門田宗之, 川端豊, 松浦朋美, 伊勢孝之, 楠瀬賢也, 山口浩司, 八木秀介, 山田博胤, 添木武, 若槻哲三, 秦広樹, 佐田政隆 :
滲出性収縮性心膜炎の1例,
第119回日本循環器学会四国地方会, 2021年12月. 數藤久美子, 福田大受, 伊勢孝之, 楠瀬賢也, 山口浩司, 八木秀介, 山田博胤, 添木武, 若槻哲三, 佐田政隆 :
マクロファージ特異的DNaseII欠損が動脈硬化に与える影響,
第119回日本循環器学会四国地方会, 2021年12月. 川端豊, 若槻哲三, 山口浩司, 門田宗之, 伊勢孝之, 楠瀬賢也, 松浦朋美, 八木秀介, 福田大受, 山田博胤, 添木武, 佐田政隆 :
冠動脈塞栓症を発症した2症例の臨床的検討,
第69回日本心臓病学会学術集会, 2021年9月. 伊勢孝之, 川端豊, 高橋智紀, 山口浩司, 福田大受, 若槻哲三, 佐村高明, 藤本鋭貴, 秦広樹, 佐田政隆 :
アクセス困難症例に対し，右鎖骨下動脈アプローチでTAVI施行した1例,
第27回日本心血管インターベンション治療学会(CVIT)中国四国地方会, 2021年9月. 川端豊, 若槻哲三, 山口浩司, 高橋智紀, 伊勢孝之, 福田大受, 佐田政隆 :
回旋枝入口部線維製性プラークに対してOASを用いstentess PCIを施行で来た1例,
第27回日本心血管インターベンション治療学会(CVIT)中国四国地方会, 2021年9月. 伊勢孝之, 川端豊, 高橋智紀, 山口浩司, 福田大受, 若槻哲三, 佐田政隆 :
Withコロナに対した心臓カテーテルオンライン臨床実習システムの構築,
第27回日本心血管インターベンション治療学会(CVIT)中国四国地方会, 2021年9月. 吉田知哉, 瀬野弘光, 松本和久, 松浦朋美, 西條良仁, 門田宗之, 川端豊, 楠瀬賢也, 伊勢孝之, 添木武, 山口浩司, 八木秀介, 山田博胤, 若槻哲三, 多田恵曜, 佐田政隆 :
ペースメーカー植え込み後に発覚した側頭葉てんかんによる発作性心静止の一例,
第263回徳島医学会学術集会, 2021年8月. Tserensonom Munkhtsetseg, 八木秀介, 伊勢孝之, 門田宗之, 川端豊, 西條良仁, 松浦朋美, 楠瀬賢也, 山口浩司, 福田大受, 山田博胤, 添木武, 若槻哲三, 佐田政隆 :
動脈硬化性疾患の高リスク患者において大動脈弁の石灰化と血清リポ蛋白との関連,
第263回徳島医学会学術集会, 2021年8月. 手束一貴, 高橋智紀, 西條良仁, 川端豊, 門田宗之, 松浦朋美, 伊勢孝之, 山口浩司, 八木秀介, 福田大受, 山田博胤, 添木武, 若槻哲三, 佐村高明, 秦広樹, 佐田政隆 :
ポスタ-セッション左冠動脈主幹部の急性冠症候群の2症例,
第263回徳島医学会学術集会(令和3年度夏期), 2021年8月. 伊勢孝之, 門田宗之, 川端豊, 楠瀬賢也, 山口浩司, 八木秀介, 福田大受, 山田博胤, 添木武, 若槻哲三, 佐村高明, 藤本鋭貴, 秦広樹, 佐田政隆 :
合同シンポジウムカテ-テル大動脈弁置換術(TAVI)によって激変した大動脈弁狭窄症治療,
第263回徳島医学会学術集会(令和3年度夏期), 2021年8月. 伊勢孝之, 石井亜由美, 西川幸治, 門田宗之, 鈴木佳子, 大南博和, 八木秀介, 佐田政隆 :
大動脈狭窄症に対するTAVI後認知機能の変化,
第11回日本脳血管・認知症学会総会, 2021年8月. 伊勢孝之, 川端豊, 高橋智紀, 山口浩司, 福田大受, 若槻哲三, 佐村高明, 藤本鋭貴, 秦広樹, 佐田政隆 :
TAVI術中に上行大動脈解離を合併し，PCIと自己拡張型TAVI弁留置によってbailoutできた症例,
第27回日本心血管インターベンション治療学会(CVIT)中国四国地方会, 2021年8月. 添木武, 福田大受, 松浦朋美, 飛梅威, 伊勢孝之, 楠瀬賢也, 山口浩司, 八木秀介, 山田博胤, 若槻哲三, 佐田政隆 :
Toll-Like Receptor 9 Is a Novel Therapeutic Target to Prevent Atrial Fibrillation,
JHRS2021 第67回日本不整脈心電学会学術大会, 2021年7月. 大南博和, 北村彩乃, 山口未来, 滝川真輝, 大西康太, 増田真志, 奥村仙示, 伊勢孝之, 八木秀介, 福田大受, 山田博胤, 佐田政隆, 竹谷豊 :
心不全マウスを用いた心リハ評価系の確立,
第27回日本心臓リハビテーション学会, 2021年6月. 西川幸治, 伊勢孝之, 石井亜由美, 鈴木佳子, 大南博和, 門田宗之, 八木秀介, 加藤真介, 佐田政隆 :
AVI患者におけるADLスコア(FIM)の変化,
第27回日本心臓リハビリテーション学会学術集会, 2021年6月. 石井亜由美, 伊勢孝之, 西川幸治, 鈴木佳子, 大南博和, 門田宗之, 八木秀介, 加藤真介, 佐田政隆 :
外来心臓リハビリテーション通院に関する患者の意識調査,
第 27 回日本心臓リハビリテーション学会学術集会, 2021年6月. 西川幸治, 伊勢孝之, 石井亜由美, 鈴木佳子, 大南博和, 門田宗之, 八木秀介, 加藤真介, 佐田政隆 :
TAVI患者におけるADLスコア(FIM)の変化,
第 27 回日本心臓リハビリテーション学会学術集会, 2021年6月. 谷彰浩, 八木秀介, 門田宗之, 川端豊, 松浦朋美, 楠瀬賢也, 伊勢孝之, 飛梅威, 山口浩司, 福田大受, 山田博胤, 若槻哲三, 佐田政隆 :
肺動脈性肺高血圧症に対する静注プロスタグランジン投与で高心拍出を呈した症例,
第116回第118回日本循環器学会中国・四国合同地方会, 2021年6月. 藤本鋭貴, 佐村高明, 菅野幹雄, 北市隆, 門田宗之, 川端豊, 伊勢孝之, 佐田政隆, 秦広樹 :
右鎖骨下動脈アプローチを行った TAVI の1例,
第116回第118回日本循環器学会中国・四国合同地方会, 2021年6月. 藤本鋭貴, 佐村高明, 菅野幹雄, 北市隆, 門田宗之, 川端豊, 伊勢孝之, 佐田政隆, 秦広樹 :
一般演題弁膜症2 右鎖骨下動脈アプローチを行ったTAVIの1例,
日本循環器学会, 2021年6月. 大櫛祐一郎, 楠瀬賢也, 伊勢孝之, 山口浩司, 八木秀介, 福田大受, 山田博胤, 添木武, 若槻哲三, 佐田政隆 :
ループ利尿薬使用下における心保護薬併用療法の有用性,
第116回第118回日本循環器学会中国・四国合同地方会, 2021年6月. Koji Yamaguchi, Tetsuzo Wakatsuki, Yuichiroh Ohkushi, Kumiko Suto, 松本和久, Tomonori Takahashi, Muneyuki Kadota, Yutaka Kawabata, Tomomi Matsuura, Takayuki Ise, Kenya Kusunose, Takeshi Tobiume, Shusuke Yagi, Hirotsugu Yamada, Takeshi Soeki and Masataka Sata :
Early and Chronic Phased Local Coagulative Responses Following Bioresorbable-polymer Drug-eluting Stent Implantation,
第85回日本循環器学会学術集会, Mar. 2021. Yutaka Kawabata, Tetsuzo Wakatsuki, Koji Yamaguchi, Daiju Fukuda, Tomomi Matsuura, Takayuki Ise, Kenya Kusunose, Takeshi Tobiume, Shusuke Yagi, Hirotsugu Yamada, 添木武 and Masataka Sata :
Relationship between Coronary Intraplaque Microluminal Structure and Epicardial Adipose Tissue and Plaque Formation -A Fresh Cadaveric Study-,
第85回日本循環器学会学術集会, Mar. 2021. Yukina Hirata, Kenya Kusunose, 辻拓将, 藤森康平, YAMAGUCHI Natsumi, Sae Morita, Susumu Nishio, Yuichiroh Ohkushi, Hiromitsu Seno, 高橋智紀, Takayuki Ise, 飛梅威, Koji Yamaguchi, Daiju Fukuda, Shusuke Yagi, Hirotsugu Yamada, 添木武, Tetsuzo Wakatsuki, 古徳純一 and Masataka Sata :
Deep Learning for Detection of Elevated Pulmonary Artery Wedge Pressure Using Standard Chest X-Ray,
第85回日本循環器学会学術集会, Mar. 2021. 阿部美保, Kenya Kusunose, Y Okushi, Zheng Robert, Takayuki Ise, Takeshi Tobiume, Koji Yamaguchi, Shusuke Yagi, Daiju Fukuda, Hirotsugu Yamada, Takeshi Soeki and Masataka Sata :
Effects of Vitamin D Supplementation on Heart Failure Mortality from Japanese Registry of All Cardiac and Vascular Datasets,
第85回日本循環器学会学術集会, Mar. 2021. 川端豊, 若槻哲三, 山口浩司, 福田大受, 伊藤浩敬, 伊勢孝之, 楠瀬賢也, 松浦朋美, 飛梅威, 八木秀介, 山田博胤, 添木武, 佐田政隆 :
光干渉断層法で観察される冠動脈壁微小管腔構造と局所冠動脈周囲脂肪内炎症および冠動脈プラークの関連 -未固定遺体における検討-,
Beyond Angiography Japan XXV, 2021年3月. 石井亜由美, 伊勢孝之, 西川幸治, 鈴木佳子, 大南博和, 門田宗之, 八木秀介, 加藤真介, 佐田政隆 :
心臓リハビリテーションの日独比較 ∼ドイツ心リハ研修から∼,
第4回日本心臓リハビリテーション学会四国支部地方会, 2021年3月. 遠藤朱門, 八木秀介, 伊勢孝之, 門田宗之, 石井亜由美, 西川幸治, 鈴木桂子, 大南博和, 加藤真介, 佐田政隆 :
若年健常人において，終末糖化産物は筋肉量・筋力の規定因子である,
第4回日本心臓リハビリテーション学会四国支部地方会, 2021年3月. 伊勢孝之, 門田宗之, 八木秀介, 石井亜由美, 西川幸治, 鈴木佳子, 大南博和, 加藤真介, 佐田政隆 :
TAVI 実施症例の至適心臓リハビリテーションの考察,
第4回日本心臓リハビリテーション学会四国支部地方会, 2021年3月. 西川幸治, 伊勢孝之, 石井亜由美, 鈴木佳子, 大南博和, 門田宗之, 八木秀介, 加藤真介, 佐田政隆 :
TAVI 施行前後の認知機能の変化について,
第4回日本心臓リハビリテーション学会四国支部地方会, 2021年3月. 山田拓哉, 谷彰浩, 門田宗之, 伊勢孝之, 川端豊, 松浦朋美, 楠瀬賢也, 飛梅威, 山口浩司, 八木秀介, 福田大受, 山田博胤, 添木武, 若槻哲三, 佐田政隆 :
大動脈四尖弁に対してTAVIを施行した一症例,
第262回徳島医師学会学術集会, 2021年3月. 平田有紀奈, 楠瀬賢也, 辻拓将, 藤森康平, 山口夏美, 森田沙瑛, 西尾進, 大櫛祐一郎, 瀬野弘光, 高橋智紀, 伊勢孝之, 飛梅威, 山口浩司, 福田大受, 八木秀介, 山田博胤, 添木武, 若槻哲三, 古徳純一, 佐田政隆 :
ディープラーニングによる胸部X-pを用いた肺動脈圧上昇の検出,
第85回日本循環器学会学術集会, 2021年3月. Muneyuki Kadota, Shusuke Yagi, Takayuki Ise, Yutaka Kawabata, Tomomi Matsuura, Kenya Kusunose, Takeshi Tobiume, Koji Yamaguchi, Hirotsugu Yamada, Takeshi Soeki, Tetsuzo Wakatsuki and Masataka Sata :
Acute Hormonal Effect of the Angiotensin Receptor-Neprilysin Inhibitor in Patients with Chronic Heart Failure,
第85回日本循環器学会学術集会, Mar. 2021. Koji Yamaguchi, Tetsuzo Wakatsuki, Tomonori Takahashi, R Ueno, Yutaka Kawabata, Takayuki Ise, Takeshi Tobiume and Masataka Sata :
Suppressed local coagulative response after newer-generation ultrathin strut SES implantation compared to older-generation SES implantation,
第29回日本心血管インターベンション治療学会, Feb. 2021. 河野弘, 山下雄也, 内藤伸仁, 佐藤正大, 門田宗之, 伊勢孝之, 八木秀介, 佐田政隆, 軒原浩, 西岡安彦 :
高安動脈炎による難治性皮膚潰瘍に対してべペルミノゲンペルプラスミド(ヒト肝細胞増殖因子プラスミドベクター)投与が奏効した1例,
第48回日本臨床免疫学会総会, 2020年10月. Koji Yamaguchi, Tetsuzo Wakatsuki, Yuichiroh Ohkushi, Kumiko Sutou, Kazuhisa Matsumoto, Tomonori Takahashi, Muneyuki Kadota, 上野理絵, Yutaka Kawabata, Tomomi Matsura, Takayuki Ise, Kenya Kusunose, Takeshi Tobiume, Shusuke Yagi, Hirotsugu Yamada, Takeshi Soeki and Masataka Sata :
The Effect of Lower Strut Thickness and Faster Polymer Resorption on Chronic Local Coagulative Response after Drug Eluting Stent Implantation,
第84回日本循環器学会学術集会, Jul. 2020. 西川幸治, 伊勢孝之, 石井亜由美, 鈴木佳子, 大南博和, 門田宗之, 八木秀介, 加藤真介, 佐田政隆 :
TAVI後の認知機能低下に関連する因子の検討,
第26回日本心臓リハビリテーション学会学術集会, 2020年7月. 門田宗之, 八木秀介, 伊勢孝之, 石井亜由美, 西川幸治, 鈴木佳子, 大南博和, 加藤真介, 佐田政隆 :
イハブラジン導入前後の運動耐容能の推移を観察した虚血性心筋症の一例,
第26回日本心臓リハビリテーション学会学術集会, 2020年7月. 石井亜由美, 伊勢孝之, 西川幸治, 本間友佳子, 鈴木佳子, 大南博和, 門田宗之, 飛梅威, 八木秀介, 早渕康信, 加藤真介, 佐田政隆 :
心配停止をきたしQT延長症候群と診断されS-ICD植込みとなった5歳児に対する心リハの経験,
第26回日本心臓リハビリテーション学会学術集会, 2020年7月. 楠瀬賢也, 芳賀昭弘, 門田宗之, 石井亜由美, 伊勢孝之, 八木秀介, 山田博胤, 佐田政隆 :
心エコーへのAI応用について,
第26回日本心臓リハビリテーション学会学術集会, 2020年7月. 石井亜由美, 伊勢孝之, 西川幸治, 本間友佳子, 鈴木佳子, 大南博和, 門田宗之, 八木秀介, 早渕康信, 加藤真介, 佐田政隆 :
小児に関する心臓リハビリテーションの取り組みと症例から学んだこと,
第26回日本心臓リハビリテーション学会学術集会, 2020年7月. 藤本鋭貴, 伊勢孝之, 川端豊, 門田宗之, 楠瀬賢也, 木下肇 :
一般演題 Horizontal Aortaを伴ったsevere ASに対するSelf-expandable Valve implantationの経験,
第115回日本循環器学会四国地方会, 2019年12月. 門田宗之, 楠瀬賢也, 伊勢孝之, 髙橋智紀, 藤本裕太, 大櫛祐一郎, 數藤久美子, 松本和久, 上野理絵, 川端豊, 山田なお, 松浦朋美, 飛梅威, 山口浩司, 八木秀介, 山田博胤, 添木武, 若槻哲三, 佐田政隆 :
ドブダミン負荷下での血行動態評価を行った潜在性閉塞性肥大型心筋症2症例の検討,
第115回日本循環器学会四国地方会, 2019年12月. 山口浩司, 若槻哲三, 松本和久, 髙橋智紀, 上野理絵, 川端豊, 松浦朋美, 楠瀬賢也, 飛梅威, 伊勢孝之, 八木秀介, 山田博胤, 添木武, 佐田政隆 :
クライオバルーンアブレーション後の肺静脈狭窄に対するDrug coated balloonの使用経験,
第115回日本循環器学会四国地方会, 2019年12月. 山口浩司, 若槻哲三, 松本和久, 髙橋智紀, 上野理絵, 川端豊, 松浦朋美, 楠瀬賢也, 伊勢孝之, 飛梅威, 八木秀介, 山田博胤, 添木武, 佐田政隆 :
新規病変に対するDrug coated balloonの効果―局所血管反応と臨床成績について―,
第115回日本循環器学会四国地方会, 2019年12月. Yutaka Kawabata, Tetsuzo Wakatsuki, Koji Yamaguchi, Hiroyuki Ito, Ueno Rie, Takayuki Ise, Todoroki Takashi, Takeshi Tobiume and Masataka Sata :
Relationship between coronary intraplaque microluminal structures and local inflammation in adjacent epicardial adipose tissue - A fresh cadaveric study,
第28回日本心血管インターベンション治療学会, Sep. 2019. 山口浩司, 若槻哲三, 髙橋智紀, 上野理絵, 川端豊, 伊勢孝之, 飛梅威, 佐田政隆 :
アブレーション後に生じた肺静脈狭窄症に対するdrug coated balloonの使用経験,
第28回日本心血管インターベンション治療学会, 2019年9月. 山口浩司, 若槻哲三, 川端豊, 山田なお, 楠瀬賢也, 伊勢孝之, 八木秀介, 山田博胤, 添木武, 佐田政隆 :
Optical coherence omographyにより器質化血栓の存在が疑われた肺癌術後急性冠症候群の1例,
第67回日本心臓病学会学術集会, 2019年9月. 山口浩司, 若槻哲三, 髙橋智紀, 上野理絵, 川端豊, 伊勢孝之, 飛梅威, 佐田政隆 :
腎不全合併虚血肢患者に対するminimum-contrast下肢血管形成術の取り組みについて,
第26回日本心血管インターベンション治療学会中国・四国地方会, 2019年9月. 川端豊, 若槻哲三, 山口浩司, 伊勢孝之, 髙橋智紀, 上野理絵, 飛梅威, 佐田政隆 :
単冠動脈症合併重症大動脈弁狭窄症に対してTAVIを施行した1例,
第26回日本心血管インターベンション治療学会中国・四国地方会, 2019年9月. 木田貴弘, 飛梅威, 松本和久, 坂東左知子, 松浦朋美, 添木武, 志村拓哉, 髙橋智子, 谷彰浩, 藤本裕太, 大櫛祐一郎, 數藤久美子, 髙橋智紀, 上野理絵, 門田宗之, 川端豊, 坂東美佳, 山田なお, 伊藤浩敬, 伊勢孝之, 楠瀬賢也, 山口浩司, 八木秀介, 福田大受, 山田博胤, 若槻哲三, 佐田政隆 :
房室ブロックの進行に伴い明らかになり，恒久的ペースメーカー植込み術後のファーフィールドR波センシングへの関与が疑われた束枝心室間副伝導路の1例,
第259回徳島医学会学術集会, 2019年8月. 井口裕貴, 飛梅威, 松本和久, 坂東左知子, 松浦朋美, 添木武, 志村拓哉, 髙橋智子, 谷彰浩, 藤本裕太, 大櫛祐一郎, 數藤久美子, 髙橋智紀, 上野理絵, 門田宗之, 川端豊, 坂東美佳, 山田なお, 伊藤浩敬, 伊勢孝之, 楠瀬賢也, 山口浩司, 八木秀介, 福田大受, 山田博胤, 若槻哲三, 佐田政隆 :
房室ブロックの予防に順行性速伝導路と順行性遅伝導路のマッピングが有用であった順行性速伝導路の下方偏位を伴う遅速型房室結節リエントリー性頻拍の1例,
第259回徳島医学会学術集会, 2019年8月. 石井亜由美, 西川幸治, 伊勢孝之, 伊勢孝之, 鈴木佳子, 高川由利子, 八木秀介, 加藤真介, 佐田政隆 :
大動脈弁狭窄症に対するTAVI施行患者の認知機能の変化について,
第25回日本心臓リハビリテーション学会学術集会, 2019年7月. 佐田政隆, 石井亜由美, 西川幸治, 八木秀介, 伊勢孝之, 上田由佳 :
``異所性脂肪''から考える動脈硬化の成因と心臓リハビリテーションの効果,
第25回日本心臓リハビリテーション学会学術集会指定講演,日本循環器学会・日本心臓リハビリテーション学会ジョイントセッション, 2019年7月. 西川幸治, 石井亜由美, 伊勢孝之, 鈴木佳子, 高川由利子, 八木秀介, 加藤真介, 佐田政隆 :
継続的な活動量の記録は半年後の運動習慣の獲得につながるか,
第25回日本心臓リハビリテーション学会学術集会, 2019年7月. Gulinu Maimaituxun, Daiju Fukuda, Shusuke Yagi, Yukina Hirata, Takashi Iwase, Tomomi Matsuura, Takayuki Ise, Kenya Kusunose, Koji Yamaguchi, Hirotsugu Yamada, Takeshi Soeki, Tetsuzo Wakatsuki, Masataka Sata and Michio Shimabukuro :
Gender specific impact of epicardial adipose tissue thickness on coronary artery disease,
第19回日本抗加齢医学会総会, Jun. 2019. 數藤久美子, 楠瀬賢也, 松浦朋美, 山田なお, 松本和久, 上野理絵, 川端豊, 伊勢孝之, 飛梅威, 山口浩司, 八木秀介, 山田博胤, 添木武, 若槻哲三, 佐田政隆 :
進行性心不全を呈す抗ミトコンドリア抗体陽性筋炎の症例,
第114回日本循環器学会中国・四国合同地方会, 2019年6月. 谷彰浩, 楠瀬賢也, 松本和久, 松浦朋美, 伊勢孝之, 飛梅威, 山口浩司, 八木秀介, 福田大受, 山田博胤, 添木武, 若槻哲三, 赤池雅史, 佐田政隆 :
拡張期僧帽弁逆流の治療適応判断に心房心室同時ペーシングが有効であった1例,
第114回日本循環器学会中国・四国合同地方会, 2019年6月. 志村拓哉, 伊勢孝之, 川端豊, 藤本裕太, 松本和久, 上野理絵, 山田なお, 伊藤浩敬, 松浦朋美, 楠瀬賢也, 山口浩司, 八木秀介, 福田大受, 山田博胤, 添木武, 若槻哲三, 黒部裕嗣, 藤本鋭貴, 佐田政隆 :
先天性二尖弁に対するTAVIの2例,
第114回日本循環器学会中国・四国合同地方会, 2019年6月. 大池由夏, 飛梅威, 松本和久, 山田なお, 坂東左知子, 松浦朋美, 伊勢孝之, 楠瀬賢也, 山口浩司, 若槻哲三, 添木武, 山田博胤, 佐田政隆 :
His束より上方レベルの心房刺激でのみ誘発可能であった房室結節リエントリー性頻拍の1例,
第114回日本循環器学会中国・四国合同地方会, 2019年6月. 中村昌史, 川端豊, 伊勢孝之, 藤本裕太, 原田貴文, 松本和久, 西條良仁, 上野理絵, 山田なお, 伊藤浩敬, 轟貴史, 楠瀬賢也, 飛梅威, 山口浩司, 福田大受, 八木秀介, 山田博胤, 添木武, 若槻哲三, 佐田政隆 :
経食道心エコーガイド下の経皮的腫瘍生検により早期に診断し得た心臓原発血管肉腫の一例,
第114回日本循環器学会中国・四国合同地方会, 2019年6月. 森田沙瑛, 楠瀬賢也, 平田有紀奈, 鳥居裕太, 天野理江, 西條良仁, 山田なお, 西尾進, 山尾雅美, 阿部美保, 伊勢孝之, 山田博胤, 佐田政隆 :
全身性強皮症における運動誘発性肺高血圧症の高リスク群の同定,
日本心エコー図学会第30回学術集会, 2019年5月. Gulinu Maimaituxun, Daiju Fukuda, Shusuke Yagi, Yukina Hirata, T Iwase, S Takao, Tomomi Matsuura, Takayuki Ise, Kenya Kusunose, Takeshi Tobiume, Koji Yamaguchi, Hirotsugu Yamada, Takeshi Soeki, Tetsuzo Wakatsuki, Masafumi Harada, Masataka Sata and Michio Shimabukuro :
Kidney fat and its impact on coronary artery disease,
第4回日本血管不全学会学術集会・総会, Apr. 2019. Gulinu Maimaituxun, Daiju Fukuda, Shusuke Yagi, Yukina Hirata, T Iwase, S Takao, Tomomi Matsuura, Takayuki Ise, Kenya Kusunose, Takeshi Tobiume, Koji Yamaguchi, Hirotsugu Yamada, Takeshi Soeki, Tetsuzo Wakatsuki, Masafumi Harada, Masataka Sata and Michio Shimabukuro :
Peri-renal fat volume is negatively associated with the adiponectin expression in human,
第4回日本血管不全学会学術集会・総会, Apr. 2019. 石井亜由美, 西川幸治, 伊勢孝之, 鈴木佳子, 八木秀介, 高川由利子, 加藤真介, 佐田政隆 :
外来心臓リハビリテーションにより外出への不安感が軽減し運動耐容能の向上を認めた症例,
日本心臓リハビリテーション学会第3回四国支部地方会, 2019年4月. 石井亜由美, 西川幸治, 伊勢孝之, 鈴木佳子, 高川由利子, 八木秀介, 加藤真介, 佐田政隆 :
Wearable ICD装着患者に対する心リハの経験,
日本心臓リハビリテーション学会第3回四国支部地方会, 2019年4月. 伊藤浩敬, 若槻哲三, 山口浩司, 福田大受, 川端豊, 轟貴史, 松浦朋美, 伊勢孝之, 楠瀬賢也, 飛梅威, 八木秀介, 山田博胤, 添木武, 佐田政隆 :
Microluminal structures of coronary plaque and vasa vasorums affect coronary inflammation: A fresh cadaveric studys,
第83回日本循環器学会学術集会, 2019年3月. 川端豊, 若槻哲三, 山口浩司, 伊藤浩敬, 福田大受, 轟貴史, 松浦朋美, 伊勢孝之, 楠瀬賢也, 飛梅威, 八木秀介, 山田博胤, 添木武, 佐田政隆 :
Coronary intraplaque microluminal structure are associated with the quality and quantity of epicardial adipose tissue -A fresh cadaveric stury-,
第83回日本循環器学会学術集会, 2019年3月. 藤本裕太, 楠瀬賢也, 西條良仁, Robert Zheng, 原田貴文, 松本和久, 上野理絵, 川端豊, 山田なお, 伊藤浩敬, 轟貴史, 伊勢孝之, 飛梅威, 山口浩司, 八木秀介, 添木武, 山田博胤, 添木武, 若槻哲三, 黒部裕嗣, 佐田政隆 :
Staphylococcus による感染性内膜炎の一例,
第113回日本循環器学会四国合同地方会, 2018年12月. Robert Zheng, 伊勢孝之, 川端豊, 八木秀介, 西條良仁, 上野理絵, 坂東美佳, 伊藤浩敬, 轟貴史, 松浦朋美, 楠瀬賢也, 飛梅威, 山口浩司, 福田大受, 山田博胤, 添木武, 若槻哲三, 黒部裕嗣, 藤本鋭貴, 北川哲也, 佐田政隆 :
Single coronary 合併重症ASに対してTAVIを施行し救命し得た1例,
第113回日本循環器学会四国合同地方会, 2018年12月. Kenya Kusunose, Yuta Torii, Takayuki Ise, Hirotsugu Yamada and Masataka Sata :
Incremental Prognostic Value of Diastolic Dysfunction by updated recommendation,
第22回日本心不全学会学術集会(東京), Oct. 2018. 伊藤浩敬, 若槻哲三, 山口浩司, 福田大受, 川端豊, 伊勢孝之, 楠瀬賢也, 松浦朋美, 轟貴史, 飛梅威, 八木秀介, 山田博胤, 添木武, 佐田政隆 :
未固定遺体における冠動脈壁小管腔構造と局所心臓周囲脂肪内炎症との関連,
第66回日本心臓病学会学術集会, 2018年9月. 山口浩司, 若槻哲三, 西條良仁, 上野理絵, 川端豊, 坂東美佳, 伊藤浩敬, 轟貴史, 松浦朋美, 伊勢孝之, 楠瀬賢也, 飛梅威, 八木秀介, 山田博胤, 添木武, 佐田政隆 :
第三世代薬剤溶出性ステント留置後における局所凝固反応塗装ステント長の関連性,
第66回日本心臓病学会学術集会, 2018年9月. 平田有紀奈, 楠瀬賢也, 山田博胤, 鳥居裕太, 西尾進, 西條良仁, 坂東美佳, 伊勢孝之, 山口浩司, 添木武, 若槻哲三, 佐田政隆 :
過度に蓄積した心外膜下脂肪は薬剤溶出型ステント留置後の再狭窄を予測するマーカーとなる,
第66回日本心臓病学会学術集会, 2018年9月. 轟貴史, 若槻哲三, 山口浩司, 數藤久美子, 原田貴文, 上野理絵, 西條良仁, 川端豊, 伊藤浩敬, 伊勢孝之, 飛梅威, 佐田政隆 :
ステント遠位部狭窄病変の関与が疑われた2枝同時発症の超遅発性ステント血栓症の1例,
第25回日本心血管インターベーション治療学会(CVIT)中国・四国地方会, 2018年9月. 川端豊, 若槻哲三, 山口浩司, 伊藤浩敬, 上野理絵, 伊勢孝之, 轟貴史, 飛梅威, 佐田政隆 :
光干渉断層法で観察される冠動脈壁微小管腔構造と局所周囲脂肪炎症との関連-未固定遺体における検討-,
第25回日本心血管インターベーション治療学会(CVIT)中国・四国地方会, 2018年9月. 伊藤浩敬, 添木武, 松浦朋美, 伊勢孝之, 楠瀬賢也, 飛梅威, 山口浩司, 八木秀介, 山田博胤, 若槻哲三, 佐田政隆 :
AVNRTアブレーション治療後に発生したJunctional Tachycardiaの1例,
第112回日本循環器学会中国・四国合同地方会, 2018年6月. 轟貴史, 若槻哲三, 山口浩司, 瀬野弘光, 數藤久美子, 西條良仁, 川端豊, 上野理絵, 伊藤浩敬, 松浦朋美, 楠瀬賢也, 伊勢孝之, 飛梅威, 八木秀介, 福田大受, 山田博胤, 添木武, 佐田政隆 :
EES留置3年後，術前に抗血小板剤中止しペパリン置換したにもかかわらず2枝同時ステント閉塞を起こした1例,
第112回日本循環器学会中国・四国合同地方会, 2018年6月. Robert Zheng, 數藤久美子, 楠瀬賢也, 松浦朋美, 瀬野弘光, 西條良仁, 上野理絵, 川端豊, 坂東美佳, 伊藤浩敬, 轟貴史, 伊勢孝之, 飛梅威, 山口浩司, 八木秀介, 福田大受, 山田博胤, 添木武, 若槻哲三, 佐田政隆 :
薬物治療が著効したSLE関連心筋炎の一例,
第112回日本循環器学会中国・四国合同地方会, 2018年6月. 西條良仁, 楠瀬賢也, 山田博胤, 西尾進, 瀬野弘光, 數藤久美子, 川端豊, 上野理絵, 伊藤浩敬, 轟貴史, 松浦朋美, 伊勢孝之, 飛梅威, 山口浩司, 八木秀介, 添木武, 若槻哲三, 佐田政隆 :
アトラサイクリン系抗癌剤による心筋障害の局在性および化学療法関連心筋障害との関連の検討,
第112回日本循環器学会中国・四国合同地方会, 2018年6月. 西尾進, 楠瀬賢也, 平田有紀奈, 鳥居裕太, 天野里江, 山尾雅美, 伊藤浩敬, 伊勢孝之, 山口浩司, 若槻哲三, 山田博胤, 佐田政隆 :
左上肢の脱力で脳卒中センターへ搬送された急性冠症候群の1例,
超音波検査技術, Vol.43, No.3, 363, 2018年6月. Yoshihito Saijoh, Kenya Kusunose, Hirotsugu Yamada, Susumu Nishio, Yukina Hirata, Yuta Torii, Kumiko Sutou, 上野理絵, Yutaka Kawabata, Hiroyuki Itou, Takafumi Todoroki, Tomomi Matsuura, Takayuki Ise, Takeshi Tobiume, Koji Yamaguchi, Shusuke Yagi, Takeshi Soeki, Tetsuzo Wakatsuki and Masataka Sata :
Anthracyclines induce early changes in localized left ventricular dysfunction.,
第82回日本循環器学会, Mar. 2018. Takeshi Soeki, Tomomi Matsuura, Daiju Fukuda, Takeshi Tobiume, Kenya Kusunose, Takayuki Ise, Koji Yamaguchi, Shusuke Yagi, Hirotsugu Yamada, Tetsuzo Wakatsuki and Masataka Sata :
C-type natriuretic peptide improves left ventricular diastolic dysfunction in HFpEF model rats.,
第82回日本循環器学会, Mar. 2018. Yutaka Kawabata, Takeshi Soeki, Takayuki Ise, Tomomi Matsuura, Yoshihito Saijoh, Takeshi Tobiume, Shusuke Yagi, Koji Yamaguchi, Hirotsugu Yamada, Tetsuzo Wakatsuki and Masataka Sata :
Effects of L-/N-type Calcium Channel Blocker on Proteinuria and Angiotensin -renin Feedback in Hypertensive Patients,
第82回日本循環器学会, Mar. 2018. Takayuki Ise, Shusuke Yagi, Yutaka Kawabata, Seno Hiromitsu, Kumiko Sutou, Yoshihito Saijoh, Rie Ueno, Hiroyuki Ito, Takafumi Todoroki, Tomomi Matsuura, Kenya Kusunose, Takeshi Tobiume, Koji Yamaguchi, Hirotsugu Yamada, Takeshi Soeki, Tetsuzo Wakatsuki and Masataka Sata :
Acute Hemodynamic Effect of Handgrip Stress in Patients with Chronic Heart Failure.,
第82回日本循環器学会, Mar. 2018. Koji Yamaguchi, Tetsuzo Wakatsuki, Yutaka Kawabata, Hiroyuki Itou, Takafumi Todoroki, Tomomi Matsuura, Takayuki Ise, Kenya Kusunose, Takeshi Tobiume, Shusuke Yagi, Hirotsugu Yamada, Takeshi Soeki and Masataka Sata :
Differential Response of Local Coagulation after Coronary Angioplasty with Paclitaxel.,
第82回日本循環器学会, Mar. 2018. Tetsuzo Wakatsuki, Koji Yamaguchi, Daiju Fukuda, Yutaka Kawabata, 轟貴史, Tomomi Matsuura, Takayuki Ise, Kenya Kusunose, Takeshi Tobiume, Shusuke Yagi, Hirotsugu Yamada, Takeshi Soeki and Masataka Sata :
Growth of vasa vasorum is associated with local inflammation around coronary plaque in fresh cadavers.,
第82回日本循環器学会, Mar. 2018. Hiroyuki Ito, Tetsuzo Wakatsuki, Koji Yamaguchi, Daiju Fukuda, Yutaka Kawabata, 轟貴史, Tomomi Matsuura, Takayuki Ise, Kenya Kusunose, Takeshi Tobiume, Shusuke Yagi, Hirotsugu Yamada, Takeshi Soeki and Masataka Sata :
Growth of Vasa Vasorum is Associated with Local Inflammation around Coronary Plaque in Fresh Cadavers(和訳中),
日本循環器学会学術集会抄録集, PJ007-3, Mar. 2018. Koji Yamaguchi, Tetsuzo Wakatsuki, Yutaka Kawabata, Hiroyuki Ito, 轟貴史, Tomomi Matsuura, Takayuki Ise, Kenya Kusunose, Takeshi Tobiume, Shusuke Yagi, Hirotsugu Yamada, Takeshi Soeki and Masataka Sata :
Differential Response of Local Coagulation after Coronary Angioplasty with Paclitaxel(和訳中),
日本循環器学会学術集会抄録集, PJ022-1, Mar. 2018. Yutaka Kawabata, Takeshi Soeki, Takayuki Ise, Tomomi Matsuura, Kenya Kusunose, Takeshi Tobiume, Shusuke Yagi, Koji Yamaguchi, Hirotsugu Yamada, Tetsuzo Wakatsuki and Masataka Sata :
Effects of L-/N-type Calcium Channel Blocker on Proteinuria and Angiotensin II-renin Feedback in Hypertensive Patients(和訳中),
日本循環器学会学術集会抄録集, PJ067-4, Mar. 2018. Gulinu Maimaituxun, Michio Shimabukuro, Daiju Fukuda, Shusuke Yagi, Yukina Hirata, Takashi Iwase, Shoichiro Takao, Tomomi Matsuura, Takayuki Ise, Tetsuzo Wakatsuki, Masafumi Harada and Masataka Sata :
The impact of epicardial adipose tissue thickness on left ventricular diastolic dysfunction in patients with preserved ejection fraction,
日本老年医学会四国地方会, Feb. 2018. 八木秀介, 伊勢孝之, 川端豊, 伊藤浩敬, 楠瀬賢也, 山口浩司, 山田博胤, 若槻哲三, 赤池雅史, 佐田政隆 :
経カテーテル大動脈弁植込み術を施した超高齢大動脈弁狭窄症の1例,
日本老年医学会四国地方会, 2018年2月. 志村拓哉, 西條良仁, 山口浩司, 楠瀬賢也, 山田博胤, 瀬野弘光, 數藤久美子, 上野理絵, 川端豊, 伊藤浩敬, 轟貴史, 松浦朋美, 伊勢孝之, 飛梅威, 八木秀介, 添木武, 若槻哲三, 佐田政隆 :
下肢静脈血栓症の誘因となる下肢血流障害の検討-下肢静脈造影での検討-,
第111回日本循環器学会四国地方会, 2017年12月. 豊田直人, 轟貴史, 添木武, 瀬野弘光, 數藤久美子, 西條良仁, 上野理絵, 川端豊, 伊藤浩敬, 松浦朋美, 伊勢孝之, 楠瀬賢也, 飛梅威, 山口浩司, 福田大受, 八木秀介, 山田博胤, 若槻哲三, 佐田政隆 :
診断から40年後に治療しえた著明なBroad Kent束を有するWPW症候群の一例,
第111回日本循環器学会四国地方会, 2017年12月. 中野睦基, 川端豊, 添木武, 松浦朋美, 飛梅威, 瀬野弘光, 數藤久美子, 西條良仁, 上野理絵, 伊藤浩敬, 轟貴史, 楠瀬賢也, 伊勢孝之, 山口浩司, 八木秀介, 山田博胤, 若槻哲三, 佐田政隆 :
嚥下性失神に対して高級性ペースメーカー植え込み術が有効であった1例,
第111回日本循環器学会四国地方会, 2017年12月. 矢野哲弘, 松浦朋美, 數藤久美子, 瀬野弘光, 西條良仁, 上野理絵, 川端豊, 伊藤浩敬, 轟貴史, 伊勢孝之, 楠瀬賢也, 飛梅威, 山口浩司, 八木秀介, 福田大受, 山田博胤, 添木武, 若槻哲三, 佐田政隆 :
心房細動アブレーション後の医原性心房中隔欠損残存により右心不全症状をきたした一例,
第111回日本循環器学会四国地方会, 2017年12月. 川端豊, 若槻哲三, 山口浩司, 伊藤浩敬, 福田大受, 伊勢孝之, 楠瀬賢也, 松浦朋美, 轟貴史, 廣野明, 飛梅威, 八木秀介, 山田博胤, 添木武, 佐田政隆 :
未固定遺体における管脈プラーク性状と局所周囲脂肪内炎症物質との関連,
第65回日本心臓病学会学術集会, 2017年9月. 山口浩司, 若槻哲三, 川端豊, 伊藤浩敬, 轟貴史, 松浦朋美, 楠瀬賢也, 飛梅威, 伊勢孝之, 八木秀介, 山田博胤, 添木武, 佐田政隆 :
Biodegradable polymer SESの慢性期局所血管反応の検討-Durable polymer SESとの比較-,
第65回日本心臓病学会学術集会, 2017年9月. 西條良仁, 楠瀬賢也, 山田博胤, 瀬野弘光, 西尾進, 伊藤浩敬, 轟貴史, 伊勢孝之, 松浦朋美, 飛梅威, 山口浩司, 八木秀介, 若槻哲三, 佐田政隆 :
経食道心エコー図検査の再検によりvegetationを同定しえた感染性心内膜炎の一例,
第65回日本心臓病学会学術集会, 2017年9月. 轟貴史, 八木秀介, 楠瀬賢也, 伊勢孝之, 西條良仁, 瀬野弘光, 廣野明, 松浦朋美, 福田大受, 山口浩司, 山田博胤, 添木武, 若槻哲三, 赤池雅史, 佐田政隆 :
膠原病患者での肺動脈楔入圧と左室拡張期末期圧の関係,
第65回日本心臓病学会学術集会, 2017年9月. 若槻哲三, 山口浩司, 福田大受, 川端豊, 伊藤浩敬, 伊勢孝之, 楠瀬賢也, 八木秀介, 山田博胤, 添木武, 佐田政隆 :
微小管腔構造を認める冠動脈壁の組織性状の評価-未固定遺体における検討-,
第65回日本心臓病学会学術集会, 2017年9月. Kenya Kusunose, Hirotsugu Yamada, Susumu Nishio, Yuta Torii, Yukina Hirata, Hiromitsu Seno, Yoshihito Saijoh, Takayuki Ise, Koji Yamaguchi, Shusuke Yagi, Takeshi Soeki, Tetsuzo Wakatsuki and Masataka Sata :
Preload Stress Echocardiography Predicts Outcomes in Patients with Pre-served Ejection Fraction and Low Gradient Aortic Stenosis,
第65回日本心臓病学会学術集会, Sep. 2017. 山口浩司, 若槻哲三, 川端豊, 伊藤浩敬, 轟貴史, 伊勢孝之, 飛梅威, 佐田政隆 :
OPTIMOカテーテル使用後に生じた巨大血管解離の1例,
第24回日本心血管インターベーション治療学会中国・四国地方会, 2017年9月. 轟貴史, 若槻哲三, 山口浩司, 川端豊, 伊藤浩敬, 伊勢孝之, 廣野明, 飛梅威, 佐田政隆 :
局所的な右腎動脈狭窄を認め血管内超音波を併用し経皮的腎動脈形成術を施行した繊維筋性異形成症の1症例,
第24回日本心血管インターベーション治療学会中国・四国地方会, 2017年9月. 川端豊, 若槻哲三, 山口浩司, 伊藤浩敬, 伊勢孝之, 轟貴史, 飛梅威, 佐田政隆 :
SES留置遠隔期に再狭窄とPSSを同時に認めた病変に対するDCB治療の効果の検討-局所凝固反応の観点から-,
第24回日本心血管インターベーション治療学会中国・四国地方会, 2017年9月. 荒瀬美晴, 飛梅威, 伊藤浩敬, 松浦朋美, 添木武, 瀬野弘光, 西條良仁, 川端豊, 轟貴史, 伊勢孝之, 楠瀬賢也, 山口浩司, 八木秀介, 山田博胤, 若槻哲三, 佐田政隆 :
薬物療法の継続が困難で頻脈誘発性心筋症を生じたが，カテーテルアブレーションにて合併症なく根治に成功した洞房リエントリー性頻拍の1例,
第255回徳島医学会学術集会, 2017年8月. Hiroyuki Ito, Tetsuzo Wakatsuki, Koji Yamaguchi, Yutaka Kawabata, Akira Hirono, Takafumi Todoroki, Takayuki Ise, Takeshi Tobiume and Masataka Sata :
The relationship between coronary plaque characteristics and local inflammation in adjacent epicardial adipose tissue in fresh cadaveric models,
第26回日本心血管インターベンション治療学会学術集会:京都, Jul. 2017. Yutaka Kawabata, Tetsuzo Wakatsuki, Koji Yamaguchi, 伊藤浩敬, Takayuki Ise, Akira Hirono, Takafumi Todoroki, Takeshi Tobiume and Masataka Sata :
A first assessment of coronary plaque characteristics, adjacent epivascular adipose tissue, and histopathological findings in fresh cadaveric model-a case report-,
第26回日本心血管インターベンション治療学会学術集会:京都, Jul. 2017. 瀬野弘光, 添木武, 松浦朋美, 伊勢孝之, 楠瀬賢也, 山口浩司, 山田博胤, 若槻哲三, 佐田政隆 :
計算負荷試験で誘発された心室性期外収縮の一例,
第110回日本循環器学会中国・四国合同地方会, 2017年6月. 伊藤浩敬, 飛梅威, 添木武, 大櫛祐一郎, 瀬野弘光, 西條良仁, 川端豊, 轟貴史, 廣野明, 松浦朋美, 楠瀬賢也, 伊勢孝之, 山口浩司, 八木秀介, 山田博胤, 若槻哲三, 佐田政隆 :
左鎖骨下への植え込み型除細動器植え替え後に生じたTwiddler症候群の1例,
第110回日本循環器学会中国・四国合同地方会, 2017年6月. 川端豊, 伊勢孝之, 山口浩司, 若槻哲三, 楠瀬賢也, 松浦朋美, 八木秀介, 飛梅威, 山田博胤, 添木武, 川谷洋平, 荒瀬裕己, 黒部裕嗣, 藤本鋭貴, 北川哲也, 佐田政隆 :
肺癌術前にバルーン大動脈弁形成術を施行し良好な開大が得られた重症大動脈弁狭窄症の一例,
第110回日本循環器学会中国・四国地方会, 2017年6月. 西條良仁, 山田博胤, 楠瀬賢也, 西尾進, 大櫛祐一郎, 瀬野弘光, 原知也, 川端豊, 伊藤浩敬, 轟貴史, 廣野明, 松浦朋美, 伊勢孝之, 飛梅威, 山口浩司, 八木秀介, 添木武, 若槻哲三, 黒部裕嗣, 渡邉俊介, 佐田政隆 :
著名な心内膜肥厚を認めた acromegalic cardiomyopathy の一例,
第110回日本循環器学会中国・四国地方会, 2017年6月. 楠瀬賢也, 山田博胤, 林修司, 伊勢孝之, 山口浩司, 八木秀介, 添木武, 若槻哲三, 佐田政隆 :
経食道心エコー図の再検査によりVegetationを同定しえた感染性心内膜炎の1例,
日本内科学会第116回四国地方会, 2017年5月. 西條良仁, Hirotsugu Yamada, Kenya Kusunose, 西尾進, 瀬野弘光, 大櫛祐一郎, 高木恵理, 上野理絵, 原知也, 川端豊, 斎藤友子, 伊藤浩敬, 轟貴史, Tomomi Matsuura, Takayuki Ise, Takeshi Tobiume, Koji Yamaguchi, Shusuke Yagi, Takeshi Soeki, Tetsuzo Wakatsuki and Masataka Sata :
Impact of Left Atrial Ischemia on Left Atrial Reservoir Function in Patients with Old Myocardial Infarction,
第81回日本循環器学会学術集会, Mar. 2017. 轟貴史, Shusuke Yagi, Kenya Kusunose, Hirotsugu Yamada, Takayuki Ise, Tomomi Matsuura, Takeshi Tobiume, Takeshi Soeki, Tetsuzo Wakatsuki, Masashi Akaike and Masataka Sata :
Serum Level of Lipoprotein (a) is a Risk Factor for Aortic Valve Sclerosis in Women,
第81回日本循環器学会学術集会, Mar. 2017. 大櫛祐一郎, Hirotsugu Yamada, Kenya Kusunose, 西條良仁, 瀬野弘光, Tomomi Matsuura, Takayuki Ise, Koji Yamaguchi, Takeshi Soeki, Tetsuzo Wakatsuki and Masataka Sata :
Accuracy of Diagnosis of Elevated Left Atrial Pressure Using Recommendation for the Evaluation of Left Ventricular Diastolic Function by Echocardiograph,
第81回日本循環器学会学術集会, Mar. 2017. 伊勢孝之, 八木秀介, 瀬野弘光, 西條良仁, 高木恵理, 上野理絵, 原知也, 伊藤浩敬, 松浦朋美, 楠瀬賢也, 飛梅威, 山口浩司, 添木武, 若槻哲三, 佐田政隆 :
Nocturnal Hypoxemia Predicts Cardiac Events in Patients with Cardiac Risk Factors,
第81回日本循環器学会学術集会, 2017年3月. 楠瀬賢也, 山田博胤, 西尾進, 平田有紀奈, 瀬野弘光, 西條良仁, 伊勢孝之, 山口浩司, 八木秀介, 添木武, 若槻哲三, 佐田政隆 :
Right Ventricular Myocardial Strain during Preload Augmentation is Associated with Exercise Capacity in Patients with Chronic Heart Failure,
第81回日本循環器学会学術集会, 2017年3月. Maimaituxun Gulinu, Michio Shimabukuro, Koji Yamaguchi, Shusuke Yagi, Tomomi Matsuura, Takayuki Ise, Kenya Kusunose, Takeshi Tobiume, Daiju Fukuda, Hirotsugu Yamada, Takeshi Soeki, Tetsuzo Wakatsuki and Masataka Sata :
Local Epicardial Adipose Tissue Thickness and Its Impact on Coronary Atherosclerosis,
第81回日本循環器学会学術集会, Mar. 2017. 伊藤浩敬, 若槻哲三, 山口浩司, 福田大受, 川端豊, 轟貴史, 松浦朋美, 楠瀬賢也, 伊勢孝之, 飛梅威, 八木秀介, 山田博胤, 添木武, 佐田政隆 :
Lipid-rich Coronary Plaque is Associated with Local Inflammation in Adjacent Epicardial Adipose Tissue in Fresh Cadaveric Models,
第81回日本循環器学会学術集会, 2017年3月. Tetsuzo Wakatsuki, Koji Yamaguchi, 伊藤浩敬, Daiju Fukuda, 川端豊, 轟貴史, Tomomi Matsuura, Takayuki Ise, Kenya Kusunose, Takeshi Tobiume, Shusuke Yagi, Hirotsugu Yamada, Takeshi Soeki and Masataka Sata :
The Tissue Characteristics of Coronary Plaque with Microluminal Structures Identified by OCT Associated with Local Inflammatory Response in Fresh Cadavers,
第81回日本循環器学会学術集会, Mar. 2017. Koji Yamaguchi, Tetsuzo Wakatsuki, 伊藤浩敬, 川端豊, 轟貴史, Tomomi Matsuura, Kenya Kusunose, Takayuki Ise, Takeshi Tobiume, Shusuke Yagi, Hirotsugu Yamada, Takeshi Soeki and Masataka Sata :
Comparison of Local Coagulative Response after Coronary Angioplasty - First Generation DES vs Second Generation-DES vs Drug Coated Balloon -,
第81回日本循環器学会学術集会, Mar. 2017. 瀬野弘光, Kenya Kusunose, Hirotsugu Yamada, 西條良仁, 西尾進, 平田有紀奈, Takayuki Ise, Koji Yamaguchi, Shusuke Yagi, Takeshi Soeki, Tetsuzo Wakatsuki and Masataka Sata :
Comparison of Right Ventricular Global Longitudinal Strain between Vender-dependent and Vender-independent Two-dimensional Speckle Tracking Software,
第81回日本循環器学会学術集会, Mar. 2017. 谷口実佑, Takeshi Soeki, Tomomi Matsuura, 佐藤裕紀, Takeshi Tobiume, 原知也, Kenya Kusunose, Takayuki Ise, Koji Yamaguchi, Shusuke Yagi, Daiju Fukuda, Hirotsugu Yamada, Tetsuzo Wakatsuki, Michio Shimabukuro and Masataka Sata :
Activated Factor X Signaling Pathway via Protease-Activated Receptor-2 is a Novel Therapeutic Target to Prevent Atrial Fibrillation,
第81回日本循環器学会学術集会, Mar. 2017. 上田浩之, 瀬野弘光, 伊勢孝之, 楠瀬賢也, 山口浩司, 山田博胤, 若槻哲三, 添木武, 東島潤, 佐田政隆 :
ベバシズマブ併用化学療法中に深部静脈血栓症および肺塞栓症を来した大腸癌の1例-血栓素因の検討も含めて,
第254回徳島医学会学術集会, 2017年2月. 山本清成, 轟貴史, 大櫛祐一郎, 上野理恵, 伊勢孝之, 瀬野弘光, 西條良仁, 高木恵理, 原知也, 川端豊, 斎藤友子, 伊藤浩敬, 松浦朋美, 飛梅威, 楠瀬賢也, 山口浩司, 八木秀介, 山田博胤, 添木武, 若槻哲三, 赤池雅史, 佐田政隆, 門田友里, 西村正人, 苛原稔 :
PET/CTにて診断できた心サルコイドーシスの1例,
第254回徳島医学会学術集会, 2017年2月. Maimaituxun Gulinu, Michio Shimabukuro, Daiju Fukuda, Shusuke Yagi, Yukina Hirata, Takashi Iwase, Shoichiro Takao, Tomomi Matsuura, Takayuki Ise, Tetsuzo Wakatsuki, Masafumi Harada and Masataka Sata :
The impact of epicardial adipose tissue thickness on left ventricular diastolic dysfunction in patients with preserved ejection fraction.,
Feb. 2017. 西川幸治, 石井亜由美, 伊勢孝之, 八木秀介, 高川由利子, 加藤真介, 佐田政隆 :
心臓リハビリテーション導入後の活動範囲の回復に関わる因子の検討,
日本心臓リハビリテーション学会第1回四国支部地方会, 2017年1月. 石井亜由美, 西川幸治, 伊勢孝之, 八木秀介, 高川由利子, 加藤真介, 佐田政隆 :
術後の廃用性筋力低下が予測された高齢開心術後患者に対しB-SESを使用した経験,
日本心臓リハビリテーション学会第1回四国支部地方会, 2017年1月. 伊勢孝之, 八木秀介, 高川由利子, 石井亜由美, 西川幸治 :
心臓リハビリテーション施行患者におけるハンドブリップ負荷の血行動態への影響,
日本心臓リハビリテーション学会第1回四国支部地方会, 2017年1月. Gulinu Maimaituxun, 島袋充生, 平田有紀奈, 岩瀬俊, 高尾正一郎, 松浦朋美, 伊勢孝之, 楠瀬賢也, 飛梅威, 山口浩司, 八木秀介, 福田大受, 山田博胤, 添木武, 若槻哲三, 原田雅史, 佐田政隆 :
局所心臓周囲脂肪厚の臨床的意義:冠動脈疾患での検討,
脳心血管抗加齢研究会2016, 2016年12月. 鈴木聖也, 山田博胤, 高木恵理, 高川由利子, 松浦朋美, 伊勢孝之, 平田有紀奈, 楠瀬賢也, 西條良仁, 瀬野弘光, 大櫛祐一郎, 西尾進, 山尾雅美, 鳥居裕太, 八木秀介, 山口浩司, 添木武, 若槻哲三, 佐田政隆 :
経食道心エコー検査により原因が究明された高齢発症の右心不全の1例,
第109回日本循環器学会四国地方会, 2016年12月. 高木恵理, 八木秀介, 伊勢孝之, 楠瀬賢也, 山口浩司, 山田博胤, 添木武, 若槻哲三, 佐田政隆, 高川由利子 :
右心不全の精査の過程で偶発的に見つかった冠静脈洞閉鎖および重複上大静脈の一例,
第109回日本循環器学会四国地方会, 2016年12月. 行重佐和香, 楠瀬賢也, 瀬野弘光, 西條良仁, 伊勢孝之, 八木秀介, 山口浩司, 山田博胤, 添木武, 若槻哲三, 佐田政隆 :
成人期に心不全症状を契機に発見された左室緻密化障害の一例,
第109回日本循環器学会四国地方会, 2016年12月. ロバートゼング, 西條良仁, 楠瀬賢也, 山田博胤, 轟貴史, 西尾進, 瀬野弘光, 高木恵理, 上野理絵, 原知也, 川端豊, 齋藤友子, 伊藤浩敬, 松浦朋美, 伊勢孝之, 飛梅威, 山口浩司, 八木秀介, 添木武, 若槻哲三, 佐田政隆 :
左上肢脱力を主訴に来院されたが心エコー図法を契機に急性冠症候群と診断しえた一例,
第109回日本循環器学会四国地方会, 2016年12月. 楠瀬賢也, 山田博胤, 西條良仁, 瀬野弘光, 大櫛祐一郎, 西尾進, 鳥居裕太, 平田有紀奈, 伊勢孝之, 八木秀介, 佐田政隆 :
肺高血圧症に対する運動負荷心エコー図法,
第53回日本臨床生理学会総会, 2016年10月. 八木秀介, 伊勢孝之, 西川幸治, 石井亜由美, 楠瀬賢也, 山口浩司, 松浦朋美, 飛梅威, 山田博胤, 添木武, 若槻哲三, 赤池雅史, 佐田政隆 :
心不全患者に対するAdaptive servo-ventilation装着下6分間歩行における運動耐容能改善効果,
第64回日本心臓病学会学術集会, 2016年9月. 瀬野弘光, 楠瀬賢也, 山田博胤, 西條良仁, 伊勢孝之, 山口浩司, 八木秀介, 添木武, 若槻哲三, 佐田政隆 :
心血管イベント発症高リスク患者における非侵襲的血管機能検査の有用性,
第64回日本心臓病学会学術集会, 2016年9月. 添木武, 高橋甲介, 松浦朋美, 楠瀬賢也, 伊勢孝之, 飛梅威, 山口浩司, 八木秀介, 福田大受, 山田博胤, 若槻哲三, 島袋充生, 佐田政隆 :
心筋虚血再灌流障害に対する新たな治療薬としてのC型ナトリウム利尿ペプチドの可能性,
第64回日本心臓病学会学術集会, 2016年9月. 西條良仁, 楠瀬賢也, 山田博胤, 瀬野弘光, 西尾進, 伊勢孝之, 八木秀介, 山口浩司, 添木武, 若槻哲三, 佐田政隆 :
下肢陽圧負荷心エコー検査により将来の左房圧上昇を予測できるか,
第64回日本心臓病学会学術集会, 2016年9月. 伊藤浩敬, 若槻哲三, 山口浩司, 伊勢孝之, 川端豊, 上野理絵, 齋藤友子, 轟貴史, 若槻哲三, 佐田政隆 :
SES留置後超遠隔期に初めて認めたPSSを伴う再狭窄病変に対してDCB治療を施行し局所凝固反応の推移を観察した一例,
第23回日本心血管インターベンション治療学会中国・四国地方会, 2016年9月. 伊勢孝之, 若槻哲三, 山口浩司, 上野理絵, 川端豊, 齋藤友子, 伊藤浩敬, 飛梅威, 佐田政隆 :
PTSMA施行2日後に遅発性完全房室ブロックを認めた1例,
第23回日本心血管インターベンション治療学会中国・四国地方会, 2016年9月. 西川幸治, 石井亜由美, 伊勢孝之, 高川由利子, 門田宗之, 八木秀介, 岩瀬俊, 加藤真介, 佐田政隆 :
退院時6MWDと入院期身体活動量の関係-MIとHFの比較,
第22回日本心臓リハビリテーション学会学術集会, 2016年7月. 石井亜由美, 西川幸治, 伊勢孝之, 高川由利子, 門田宗之, 八木秀介, 岩瀬俊, 加藤真介, 佐田政隆 :
心臓リハビリテーション患者におけるセルフエフィカシーの検討,
第22回日本心臓リハビリテーション学会学術集会, 2016年7月. 八木秀介, 伊勢孝之, 高川由利子, 西川幸治, 石井亜由美, 佐田政隆 :
SGLT2阻害薬併用心臓リハビリテーションにより運動耐容能が改善した糖尿病合併慢性心不全の1例,
第22回日本心臓リハビリテーション学会学術集会, 2016年7月. 高川由利子, 八木秀介, 伊勢孝之, 門田宗之, 佐田政隆 :
心臓リハビリテーションによる内臓・皮下脂肪量と骨格筋量に対する影響,
第22回日本心臓リハビリテーション学会学術集会, 2016年7月. H Ito, Tetsuzo Wakatsuki, Koji Yamaguchi, R Ueno, Y Saito, T Todoroki, Takayuki Ise, Takeshi Tobiume and Masataka Sata :
A case of trapped floppy rotawire at the distal portion of wrapped left anterior descending coronary artery,
第25回日本心血管インターベンション治療学会, Jul. 2016. Koji Yamaguchi, Tetsuzo Wakatsuki, R Ueno, H Ito, Y Saito, T Todoroki, Takayuki Ise, Takeshi Tobiume and Masataka Sata :
Suppressive Local Vascular Response after Paclitaxel Eluting Balloon Compared to Paclitaxel Eluting Stent,
第25回日本心血管インターベンション治療学会, Jul. 2016. 原知也, 山田博胤, 伊勢孝之, 楠瀬賢也, 飛梅威, 山口浩司, 八木秀介, 添木武, 若槻哲三, 佐田政隆 :
重症心不全を呈したBecker型筋ジストロフィーの1剖検例,
第108回日本循環器学会中国・四国合同地方会, 2016年6月. 原知也, 飛梅威, 伊勢孝之, 楠瀬賢也, 山口浩司, 八木秀介, 山田博胤, 添木武, 若槻哲三, 佐田政隆 :
心房細動アブレーション後に麻痺性胃拡張を来した一例,
第108回日本循環器学会中国・四国合同地方会, 2016年6月. 山上圭, 西條良仁, 楠瀬賢也, 山田博胤, 瀬野弘光, 原知也, 上野理絵, 門田宗之, 齋藤友子, 山﨑宙, 坂東左知子, 伊藤浩敬, 轟貴史, 松浦朋美, 伊勢孝之, 飛梅威, 山口浩司, 八木秀介, 添木武, 若槻哲三, 佐田政隆 :
生体腎移植後における腎静脈-外腸骨静脈間の血流動態変化が一因と考えられた深部静脈血栓症の一例,
第108回日本循環器学会中国・四国合同地方会, 2016年6月. 伊勢孝之, 八木秀介, 門田宗之, 瀬野弘光, 西條良仁, 上野理絵, 原知也, 齋藤友子, 山﨑宙, 坂東左知子, 伊藤浩敬, 轟貴史, 松浦朋美, 楠瀬賢也, 飛梅威, 山口浩司, 山田博胤, 添木武, 若槻哲三, 佐田政隆 :
循環器病棟入院患者における睡眠時無呼吸，夜間低酸素血症の合併 ∼連続パルスオキシメータを用いた解析∼,
第108回日本循環器学会中国・四国合同地方会, 2016年6月. 伊藤浩敬, 若槻哲三, 山口浩司, 伊勢孝之, 上野理絵, 齋藤友子, 八木秀介, 山田博胤, 添木武, 佐田政隆 :
シロリムス溶出ステント留置7年後に初めて造影剤ステント周囲滲み出し像を認めその後も増大を呈した1例,
日本内科学会第114回四国地方会, 2016年5月. 西條良仁, 山田博胤, 楠瀬賢也, 瀬野弘光, 伊勢孝之, 八木秀介, 山口浩司, 添木武, 若槻哲三, 佐田政隆 :
ペースメーカー植込み術後に等容拡張期の異常な左室中部流入血流を認めた1例,
日本内科学会第114回四国地方会, 2016年5月. 西條良仁, 山田博胤, 楠瀬賢也, 瀬野弘光, 伊勢孝之, 八木秀介, 山口浩司, 添木武, 若槻哲三, 佐田政隆 :
ハンドグリップ負荷心エコー検査が心房細動合併心不全の治療評価に有用であった1例,
日本内科学会第114回四国地方会, 2016年5月. 山崎宙, 西條良仁, 伊勢孝之, 楠瀬賢也, 山口浩司, 若槻哲三, 佐田政隆, 木下肇, 黒部裕嗣, 北川哲也 :
左冠動脈入口部の高度狭窄により狭心症症状を繰り返した1例,
日本内科学会第114回四国地方会, 2016年5月. 村上貴寛, 八木秀介, 齋藤友子, 山口浩司, 伊勢孝之, 楠瀬賢也, 若槻哲三, 佐田政隆, 高島啓, 倉橋清衛 :
Kallmann症候群を合併した若年重症虚血性心疾患の1例,
日本内科学会第114回四国地方会, 2016年5月. Shusuke Yagi, Ken-ichi Aihara, Daiju Fukuda, A Takashima, Mika Bando, T Hara, Takayuki Ise, Kenya Kusunose, Koji Yamaguchi, Takeshi Tobiume, Hirotsugu Yamada, Takeshi Soeki, Tetsuzo Wakatsuki, Michio Shimabukuro, Masashi Akaike and Masataka Sata :
Reduced Ratio of Eicosapentaenoic Acid and Docosahexaenoic Acid to Arachidonic Acid is Associated with Early Onset of Acute Coronary Syndrome.,
第80回日本循環器学会学術集会, Mar. 2016. Koji Yamaguchi, Tetsuzo Wakatsuki, T Hara, M Kadota, R Ueno, Mika Bando, H Yamazaki, Y Saito, S Bando, Tomomi Matsuura, Kenya Kusunose, Takayuki Ise, Takeshi Tobiume, Shusuke Yagi, Hirotsugu Yamada, Takeshi Soeki and Masataka Sata :
Local Vascular Response after Paclitaxel Eluting Balloon Angioplasty Compared to Drug Eluting Stent Implantation in Stable Angina Patients.,
第80回日本循環器学会学術集会, Mar. 2016. S Bando, Takeshi Soeki, Tomomi Matsuura, Takayuki Ise, Kenya Kusunose, Takeshi Tobiume, Koji Yamaguchi, Shusuke Yagi, Daiju Fukuda, Hirotsugu Yamada, Tetsuzo Wakatsuki, Michio Shimabukuro and Masataka Sata :
Plasma Myeloperoxidase Activity is Associated with Atrial Substrate Remodeling in Patients with Atrial Fibrillation.,
第80回日本循環器学会学術集会, Mar. 2016. Tomomi Matsuura, Takeshi Soeki, Y Morimoto, S Bando, Takayuki Ise, Kenya Kusunose, Takeshi Tobiume, Koji Yamaguchi, Shusuke Yagi, Daiju Fukuda, Hirotsugu Yamada, Tetsuzo Wakatsuki, Michio Shimabukuro and Masataka Sata :
Epicardial Adipose Tissue Produce Proinflammatory Cytokines and Influence the Pathogenesis of Atrial Fibrillation.,
第80回日本循環器学会学術集会, Mar. 2016. Shusuke Yagi, Ken-ichi Aihara, Masashi Akaike, T Hara, Takayuki Ise, Daiju Fukuda, Michio Shimabukuro and Masataka Sata :
Modulation of Tissue Thrombin Action is a Novel Therapeutic Approach for Prevention of Polyvascular Disease.,
第80回日本循環器学会学術集会, Mar. 2016. Kenya Kusunose, Hirotsugu Yamada, S Nishio, Y Hirata, H Seno, Y Saijo, Takayuki Ise, Takeshi Tobiume, Koji Yamaguchi, Shusuke Yagi, Takeshi Soeki, Tetsuzo Wakatsuki, B Griffin and Masataka Sata :
Echocardiographic Characteristics of Right Ventricular Size and Function are Associated with Cardiac Events in Sleep Apnea Syndrome.,
第80回日本循環器学会学術集会, Mar. 2016. 近藤大祐, 八木秀介, 伊勢孝之, 山口浩司, 若槻哲三, 楠瀬賢也, 松浦朋美, 飛梅威, 山田博胤, 添木武, 福田大受, 赤池雅史, 島袋充生, 佐田政隆 :
急性冠症候群発症時のイコサペント酸とドコサヘキサエン酸の血中濃度低下は慢性期冠動脈ステント内再狭窄の予測因子である,
第45回日本心脈管作動物質学会, 2016年2月. 上田雄大, 島袋充生, Maimaituxun Gulinu, Salim Masdan Hotimah, 坂東左知子, 松浦朋美, 伊勢孝之, 楠瀬賢也, 飛梅威, 山口浩司, 岩瀬俊, 八木秀介, 福田大受, 山田博胤, 添木武, 若槻哲三, 原田雅史, 佐田政隆 :
冠症候群発症例における心臓周囲脂肪および腹部脂肪分布の検討,
第45回日本心脈管作動物質学会, 2016年2月. 西川幸治, 石井亜由美, 伊勢孝之, 高川由利子, 門田宗之, 八木秀介, 岩瀬俊, 加藤真介, 佐田政隆 :
心疾患患者における身体活動量と運動耐容能の関係,
第107回日本循環器学会四国地方会, 2015年11月. 伊勢孝之, 西條良仁, 三木浩和, 賀川久美子, 瀬野弘光, 上野理絵, 原知也, 齋藤友子, 坂東美佳, 坂東左知子, 伊藤浩敬, 松浦朋美, 山口浩司, 飛梅威, 八木秀介, 山田博胤, 添木武, 若槻哲三, 安倍正博, 佐田政隆 :
auto-PBSCT とBortezomibの併用が著効した高度心機能障害を伴う原発性心アミロイドーシスの1例,
第107回日本循環器学会四国地方会, 2015年11月. 門田宗之, 伊勢孝之, 楠瀬賢也, 瀬野弘光, 上野理絵, 原知也, 齋藤友子, 高島啓, 坂東美佳, 山﨑宙, 坂東左知子, 伊藤浩敬, 飛梅威, 山口浩司, 八木秀介, 山田博胤, 添木武, 若槻哲三, 黒部裕嗣, 北川哲也, 佐田政隆 :
静脈洞型心房中隔欠損を合併した高齢難治性心不全に対し修復術が奏功した一例,
第107回日本循環器学会四国地方会, 2015年11月. 石井亜由美, 西川幸治, 伊勢孝之, 高川由利子, 門田宗之, 八木秀介, 岩瀬俊, 加藤真介, 佐田政隆 :
心疾患患者の生活習慣是正に対するセルフエフィカシーと不安・抑うつとの関係,
第107回日本循環器学会四国地方会, 2015年11月. 坂東左知子, 添木武, 松浦朋美, 飛梅威, 瀬野弘光, 西條良仁, 門田宗之, 原知也, 上野理絵, 齋藤友子, 坂東美佳, 山﨑宙, 伊藤浩敬, 伊勢孝之, 楠瀬賢也, 山口浩司, 八木秀介, 山田博胤, 若槻哲三, 佐田政隆 :
心室瘤を形成した心サルコイドーシス患者の薬剤抵抗性VT storm に対しアブレーションを行った一例,
第107回日本循環器学会四国地方会, 2015年11月. 西條良仁, 坂東美佳, 楠瀬賢也, 門田宗之, 伊勢孝之, 山田博胤, 西尾進, 山口浩司, 八木秀介, 添木武, 若槻哲三, 佐田政隆 :
ハンドグリップ負荷による心臓カテーテル検査および心エコー検査が治療評価に有用であった2例,
第107回日本循環器学会四国地方会, 2015年11月. 伊藤浩敬, 高島啓, 八木秀介, 瀬野弘光, 門田宗之, 原知也, 上野理絵, 齋藤友子, 山﨑宙, 坂東美佳, 坂東左知子, 松浦朋美, 楠瀬賢也, 伊勢孝之, 山口浩司, 飛梅威, 山田博胤, 添木武, 若槻哲三, 佐田政隆 :
重症筋無力症に対する免疫抑制療法中に生じた化膿性心膜炎の一例,
第107回日本循環器学会四国地方会, 2015年11月. 西條良仁, 齋藤友子, 山田博胤, 楠瀬賢也, 坂東美佳, 瀬野弘光, 門田宗之, 原知也, 上野理絵, 山﨑宙, 坂東左知子, 伊藤浩敬, 伊勢孝之, 山口浩司, 八木秀介, 岩瀬俊, 添木武, 若槻哲三, 佐田政隆 :
遅延造影MRI検査が診断の契機となった心アミロイドーシスの1例,
第107回日本循環器学会四国地方会, 2015年11月. 山下雄也, 伊勢孝之, 坂東美佳, 原知也, 高島啓, 山﨑宙, 齋藤友子, 坂東左知子, 楠瀬賢也, 飛梅威, 山口浩司, 八木秀介, 山田博胤, 添木武, 若槻哲三, 木下肇, 藤本鋭貴, 北川哲也, 佐田政隆 :
60歳代で発見され外科治療が奏功した大動脈縮窄症の1例,
第107回日本循環器学会四国地方会, 2015年11月. 近藤大祐, 八木秀介, 伊勢孝之, 山口浩司, 若槻哲三, 楠瀬賢也, 松浦朋美, 飛梅威, 山田博胤, 添木武, 福田大受, 赤池雅史, 島袋充生, 佐田政隆 :
急性冠症候群患者におけるスタチンのω3不飽和脂肪酸濃度へ影響,
第107回日本循環器学会四国地方会, 2015年11月. 加藤悠人, 飛梅威, 坂東左知子, 松浦朋美, 添木武, 瀬野弘光, 上野理絵, 門田宗之, 原知也, 齋藤友子, 高島啓, 山﨑宙, 坂東美佳, 伊藤浩敬, 伊勢孝之, 楠瀬賢也, 山口浩司, 八木秀介, 山田博胤, 若槻哲三, 佐田政隆 :
His束近傍に起源を認めるATP感受性心房頻拍7例に関する検討,
第107回日本循環器学会四国地方会, 2015年11月. M Kadota, Takayuki Ise, Shusuke Yagi, Kenya Kusunose, Hajime Kinoshita, Hirotsugu Kurobe, Hirotsugu Yamada, Takeshi Soeki, Tetsuzo Wakatsuki and Masataka Sata :
Successful Surgical Repair of Aged Sinus Venous Connection : A Case Report,
第19回日本心不全学会学術集会, Oct. 2015. 伊勢孝之, 若槻哲三, 山口浩司, 坂東美佳, 門田宗之, 八木秀介, 山田博胤, 添木武, 佐田政隆 :
PTSMA術後に左室流出路狭窄の急性増悪を認めたHOCMの1例,
ストラクチャークラブ・ジャパンライブデモンストレーション2015, 2015年9月. 長野広実, 添木武, 坂東左知子, 松浦朋美, 飛梅威, 楠瀬賢也, 伊勢孝之, 山口浩司, 八木秀介, 福田大受, 山田博胤, 若槻哲三, 島袋充生, 佐田政隆 :
心房細動発症の予測因子-心電学的側面と心エコー学的側面からの検討-,
第63回日本心臓病学会学術集会, 2015年9月. 坂東左知子, 添木武, 飛梅威, 松浦朋美, 伊勢孝之, 楠瀬賢也, 山口浩司, 八木秀介, 山田博胤, 若槻哲三, 佐田政隆 :
薬剤抵抗性のPurkinje起源心室頻拍に対し，人工呼吸管理・PCPS装着下にカテーテルアブレーション治療を施行し，社会復帰に成功した若年例の一例,
第63回日本心臓病学会学術集会, 2015年9月. 瀬野弘光, 山田博胤, 楠瀬賢也, 坂東美佳, 西條良仁, 西尾進, 山尾雅美, 鳥居裕太, 平田有紀奈, 伊勢孝之, 八木秀介, 添木武, 若槻哲三, 佐田政隆 :
6分間歩行負荷心エコー検査を用いた運動負荷誘発性肺高血圧症例の検出とその特徴,
第63回日本心臓病学会学術集会, 2015年9月. 伊勢孝之, 楠瀬賢也, 松浦朋美, 山口浩司, 八木秀介, 岩瀬俊, 山田博胤, 添木武, 若槻哲三, 佐田政隆 :
急性心筋梗塞後にBeckerⅠ型とⅢ型の心破裂をきたし，救命しえた一例,
第63回日本心臓病学会学術集会, 2015年9月. 西尾進, 山田博胤, 平田有紀奈, 西條良仁, 高川由利子, 坂東美佳, 林修司, 楠瀬賢也, 伊勢孝之, 山口浩司, 若槻哲三, 佐田政隆 :
冠攣縮性狭心症における心臓周囲脂肪厚の検討,
第63回日本心臓病学会学術集会, 2015年9月. 坂東美佳, 伊勢孝之, 山田博胤, 楠瀬賢也, 西尾進, 山口浩司, 八木秀介, 添木武, 若槻哲三, 佐田政隆 :
収縮期雑音を契機に発見された成人単純型大動脈縮窄症の1例,
第63回日本心臓病学会学術集会, 2015年9月. 齋藤友子, 若槻哲三, 山口浩司, 上野理絵, 山﨑宙, 伊勢孝之, 飛梅威, 佐田政隆 :
心臓カテーテル検査後に生じた橈骨仮性動脈瘤2例の検討,
第22回日本心血管インターベンション治療学会中国・四国地方会, 2015年9月. 山口浩司, 若槻哲三, 上野理絵, 齋藤友子, 山﨑宙, 伊勢孝之, 飛梅威, 佐田政隆 :
総腸骨動脈閉塞病変に対して留置したstentが大動脈中枢側へ伸展した1例,
第22回日本心血管インターベンション治療学会中国・四国地方会, 2015年9月. 伊勢孝之, 若槻哲三, 山口浩司, 上野理絵, 斎藤友子, 髙島啓, 山崎宙, 飛梅威, 佐田政隆 :
PTSMA後に左室流出路狭窄の一過性急性増悪を認めた閉塞性肥大型心筋症の1例,
第22回日本心血管インターベンション治療学会中国・四国地方会, 2015年9月. 山﨑宙, 若槻哲三, 山口浩司, 上野理絵, 齋藤友子, 伊勢孝之, 飛梅威, 佐田政隆 :
広範前壁心筋梗塞発症早期に左室内血栓を生じた2例の検討,
第22回日本心血管インターベンション治療学会中国・四国地方会, 2015年9月. H Yamazaki, Tetsuzo Wakatsuki, K Yamaguchi, Y Saito, A Takashima, Takayuki Ise, Takeshi Tobiume and Masataka Sata :
A Case of Preoperative VLST due to Multiple Inter-strut Hollow despite Heparin Replacement therapy, and OCT-guided PCI,
第24回日本心血管インターベンション治療学会, Jul. 2015. Koji Yamaguchi, Tetsuzo Wakatsuki, A Takashima, H Yamazaki, Y Saito, Takayuki Ise, Takeshi Tobiume and Masataka Sata :
Suppressive Local Coagulative and Inflammatory Response after Implantation of Biolimus-Eluting Stents,
第24回日本心血管インターベンション治療学会, Jul. 2015. 石井亜由美, 西川幸治, 伊勢孝之, 高川由利子, 八木秀介, 岩瀬俊, 加藤真介, 佐田政隆 :
当院での小児に対する心臓リハビリテーションの経験,
第21回日本心臓リハビリテーション学会, 2015年7月. 西川幸治, 石井亜由美, 伊勢孝之, 高川由利子, 八木秀介, 岩瀬俊, 加藤真介, 佐田政隆 :
治療抵抗性の収縮性新膜炎に心臓リハビリテーションが有効であった一症例,
第21回日本心臓リハビリテーション学会, 2015年7月. 八木秀介, 伊勢孝之, 西川幸治, 石井亜由美, 高川由利子, 岩瀬俊, 赤池雅史, 加藤真介, 佐田政隆 :
重症心不全患者におけるAdaptive servo-ventilation装着による運動耐容能改善効果,
第21回日本心臓リハビリテーション学会, 2015年7月. 高島啓, 門田宗之, 山口浩司, 原知也, 齋藤友子, 坂東美佳, 坂東左知子, 松浦朋美, 伊勢孝之, 楠瀬賢也, 飛梅威, 八木秀介, 岩瀬俊, 山田博胤, 添木武, 若槻哲三, 佐田政隆 :
IgA腎症の加療中に若年で発症した急性冠症候群の一例,
第106回日本循環器学会中国・四国合同地方会, 2015年6月. 山﨑宙, 山口浩司, 原知也, 高島啓, 坂東美佳, 齋藤友子, 坂東左知子, 松浦朋美, 楠瀬賢也, 伊勢孝之, 飛梅威, 八木秀介, 岩瀬俊, 山田博胤, 添木武, 若槻哲三, 佐田政隆 :
右心不全を来した収縮性心膜炎合併心膜嚢胞の一例,
第106回日本循環器学会中国・四国合同地方会, 2015年6月. 山﨑宙, 八木秀介, 鳥居裕太, 天野里江, 西尾進, 原知也, 齋藤友子, 高島啓, 坂東美佳, 坂東左知子, 松浦朋美, 伊勢孝之, 楠瀬賢也, 飛梅威, 山口浩司, 山田博胤, 添木武, 若槻哲三, 島袋充生, 赤池雅史, 佐田政隆 :
深部静脈血栓症に対するエドキサバンの凝固因子に与える影響,
第106回日本循環器学会中国・四国合同地方会, 2015年6月. 山﨑宙, 八木秀介, 原知也, 高島啓, 坂東美佳, 齋藤友子, 坂東左知子, 松浦朋美, 伊勢孝之, 楠瀬賢也, 飛梅威, 山口浩司, 岩瀬俊, 山田博胤, 添木武, 若槻哲三, 佐田政隆 :
家族性アミロイドポリニューロパチーを合併した心肥大の一例,
第106回日本循環器学会中国・四国合同地方会, 2015年6月. 坂東左知子, 添木武, 原知也, 齋藤友子, 坂東美佳, 山﨑宙, 高島啓, 松浦朋美, 伊勢孝之, 楠瀬賢也, 山口浩司, 飛梅威, 八木秀介, 山田博胤, 若槻哲三, 坂東正章, 佐田政隆 :
Brugada症候群に閉塞性肥大型心筋症を併発した一例,
第106回日本循環器学会中国・四国合同地方会, 2015年6月. 八木秀介, 山﨑宙, 楠瀬賢也, 伊勢孝之, 飛梅威, 山口浩司, 山田博胤, 添木武, 若槻哲三, 赤池雅史, 佐田政隆 :
肺アスペルギルス症に合併した肺動静脈血栓症の1例,
第106回日本循環器学会中国・四国合同地方会, 2015年6月. 瀬野弘光, 坂東美佳, 楠瀬賢也, 山田博胤, 高川由利子, 林修司, 齋藤友子, 山﨑宙, 高島啓, 坂東左知子, 松浦朋美, 伊勢孝之, 飛梅威, 山口浩司, 八木秀介, 添木武, 若槻哲三, 平田有紀奈, 西尾進, 島袋充生, 佐田政隆 :
CHADS2スコア低値例における左心耳機能の検討,
第106回日本循環器学会中国・四国合同地方会, 2015年6月. 飛梅威, 坂東左知子, 松浦朋美, 添木武, 今田久美子, 松本和久, 齋藤友子, 原知也, 高島啓, 山﨑宙, 坂東美佳, 伊勢孝之, 楠瀬賢也, 山口浩司, 八木秀介, 岩瀬俊, 山田博胤, 若槻哲三, 赤池雅史, 佐田政隆 :
心房細動カテーテルアブレーションにおける放射線防護キャビンの放射線被爆低減効果について,
第106回日本循環器学会中国・四国合同地方会, 2015年6月. 楠瀬賢也, 山田博胤, ブライアングリフィン, 坂東美佳, 西條良仁, 西尾進, 伊勢孝之, 山口浩司, 八木秀介, 添木武, 若槻哲三, 佐田政隆 :
睡眠時呼吸障害患者の右室機能評価は予後予測において有用である,
第106回日本循環器学会中国・四国合同地方会, 2015年6月. 上野理絵, 坂東美佳, 山田博胤, 楠瀬賢也, 高川由利子, 瀬野弘光, 門田宗之, 原知也, 齋藤友子, 山﨑宙, 高島啓, 坂東左知子, 松浦朋美, 伊勢孝之, 飛梅威, 山口浩司, 八木秀介, 添木武, 若槻哲三, 島袋充生, 佐田政隆 :
間質性肺炎合併膠原病性肺高血圧症にボセンタンが奏功した1例,
第106回日本循環器学会中国・四国合同地方会, 2015年6月. 鈴木智子, 楠瀬賢也, 山田博胤, 坂東美佳, 西條良仁, 西尾進, 伊勢孝之, 山口浩司, 八木秀介, 添木武, 若槻哲三, 佐田政隆 :
IGg4関連疾患に伴う巨大冠動脈瘤および冠動脈周囲偽腫瘍を認めた1例,
第106回日本循環器学会中国・四国合同地方会, 2015年6月. 楠瀬賢也, 山田博胤, 坂東美佳, 西條良仁, 西尾進, 伊勢孝之, 山口浩司, 八木秀介, 岩瀬俊, 添木武, 若槻哲三, 佐田政隆 :
膠原病に伴う肺高血圧症の悪化予測:6分間歩行負荷心エコー図検査を用いた検討,
第106回日本循環器学会中国・四国合同地方会, 2015年6月. 飛梅威, 坂東左知子, 松浦朋美, 添木武, 今田久美子, 松本和久, 原知也, 齋藤友子, 高島啓, 山﨑宙, 坂東美佳, 伊勢孝之, 楠瀬賢也, 山口浩司, 八木秀介, 岩瀬俊, 山田博胤, 若槻哲三, 赤池雅史, 佐田政隆 :
心房細動カテーテルアブレーションにおける放射線防護キャビンの放射線被爆低減効果に関する検討,
第2回日本心血管脳卒中学会学術集会, 2015年6月. 山下雄也, 坂東美佳, 楠瀬賢也, 宮本亮介, 伊勢孝之, 山口浩司, 八木秀介, 山田博胤, 添木武, 若槻哲三, 佐田政隆 :
片麻痺および間代性痙攣でStroke Care Unit入室後に高度心機能低下をきたした1例,
第2回日本心血管脳卒中学会学術集会, 2015年6月. Koji Yamaguchi, Tetsuzo Wakatsuki, T Hara, Y Takagawa, Mika Bando, A Takashima, H Yamazaki, S Bando, Tomomi Matsuura, Kenya Kusunose, Takayuki Ise, Takeshi Tobiume, Shusuke Yagi, Takashi Iwase, Hirotsugu Yamada, Takeshi Soeki and Masataka Sata :
Differential Local Vascular Responses after Implantation of Biolimus-Eluting and Everolimus-Eluting Stents Compared with Sirolimus-Eluting and Bare Metal Stents.,
第79回日本循環器学会学術集会, Apr. 2015. Takeshi Soeki, Tomomi Matsuura, S Bando, Takeshi Tobiume, T Hara, A Takashima, Mika Bando, H Yamazaki, Y Saito, Takayuki Ise, Kenya Kusunose, Koji Yamaguchi, Shusuke Yagi, Daiju Fukuda, Takashi Iwase, Hirotsugu Yamada, Tetsuzo Wakatsuki, Michio Shimabukuro and Masataka Sata :
Antiarrhythmic and Antiapoptotic Effects of C-type Natriuretic Peptide in Rats with Myocardial Ischemia/Reperfusion.,
第79回日本循環器学会学術集会, Apr. 2015. 松本康平, 楠瀬賢也, 松本和久, 高川由利子, 坂東美佳, 發知淳子, 松浦朋美, 伊勢孝之, 飛梅威, 山口浩司, 八木秀介, 岩瀬俊, 山田博胤, 添木武, 若槻哲三, 佐田政隆 :
動脈周囲炎をきたしたIgG4関連疾患の1例,
第250回徳島医学会学術集会(平成26年度冬期), 2015年2月. 鈴木智子, 山崎宙, 近藤彰, 高川由利子, 坂東美佳, 發知淳子, 松浦朋美, 楠瀬賢也, 伊勢孝之, 飛梅威, 山口浩司, 八木秀介, 岩瀬俊, 山田博胤, 添木武, 若槻哲三, 佐田政隆 :
活動性を評価するにあたりPET-CTが特に有効であった心サルコイドーシスの1例,
第250回徳島医学会学術集会(平成26年度冬期), 2015年2月. 武井美貴子, 飛梅威, 坂東左知子, 松浦朋美, 添木武, 今田久美子, 松本和久, 高川由利子, 原知也, 高島啓, 齋藤友子, 山崎宙, 坂東美佳, 伊勢孝之, 山口浩司, 八木秀介, 岩瀬俊, 山田博胤, 若槻哲三, 佐田政隆 :
生理的ペーシングへのモード変更が心不全の改善に有効であった房室ブロックの1例,
第250回徳島医学会学術集会(平成26年度冬期), 2015年2月. 今田久美子, 伊勢孝之, 八木秀介, 高木恵理, 松本和久, 高川由利子, 原知也, 高島啓, 齋藤友子, 坂東美佳, 山﨑宙, 坂東左知子, 松浦朋美, 飛梅威, 山口浩司, 岩瀬俊, 山田博胤, 添木武, 若槻哲三, 赤池雅史, 佐田政隆 :
慢性血栓塞栓性肺高血圧症にリオシグアトを使用した1症例,
第105回日本循環器学会四国地方会, 2014年12月. 伊勢孝之, 岩瀬俊, 高木恵理, 今田久美子, 松本和久, 高川由利子, 原知也, 齋藤友子, 高島啓, 山﨑宙, 坂東美佳, 坂東左知子, 松浦朋美, 飛梅威, 山口浩司, 八木秀介, 山田博胤, 添木武, 若槻哲三, 佐田政隆 :
心臓MRIガドリニウム遅延造影で検出できなかった心臓サルコイドーシス再燃の一例,
第105回日本循環器学会四国地方会, 2014年12月. 石井亜由美, 西川幸治, 伊勢孝之, 高川由利子, 八木秀介, 岩瀬俊, 木下肇, 阪田美穂, 早渕康信, 赤池雅史, 加藤真介, 北川哲也, 佐田政隆 :
単心室症患児の開心術後に心臓リハビリテーションを有効に施行し得た一例,
第105回日本循環器学会四国地方会, 2014年12月. 平田有紀奈, 山田博胤, 西尾進, 堀家由貴, 玉井佑里恵, 鳥居祐太, 天野里江, 山尾雅美, 高川由利子, 坂東美佳, 林修司, 楠瀬賢也, 伊勢孝之, 山口浩司, 八木秀介, 岩瀬俊, 添木武, 若槻哲三, 佐田政隆 :
頸動脈プラークスコア，心臓周囲脂肪厚と冠動脈硬化の関連:超音波検査を用いた検討,
第105回日本循環器学会四国地方会, 2014年12月. 高島啓, 若槻哲三, 山口浩司, 松本和久, 今田久美子, 高木恵理, 高川由利子, 原知也, 齋藤友子, 山﨑宙, 坂東美佳, 坂東左知子, 松浦朋美, 伊勢孝之, 飛梅威, 八木秀介, 岩瀬俊, 山田博胤, 添木武, 佐田政隆 :
冠動脈完全閉塞性病変の治療後慢性期に形成された二重血行路をOCTで観察し得た一例,
第105回日本循環器学会四国地方会, 2014年12月. 八木秀介, 鳥居祐太, 伊勢孝之, 山口浩司, 飛梅威, 岩瀬俊, 山田博胤, 添木武, 若槻哲三, 島袋充生, 赤池雅史, 佐田政隆 :
突然の片側性下肢腫脹を呈した変形性関節症の2例,
第105回日本循環器学会四国地方会, 2014年12月. 楠瀬賢也, 山田博胤, ポポヴィッチゾラン, 伊勢孝之, 山口浩司, 八木秀介, 岩瀬俊, 添木武, 若槻哲三, 佐田政隆 :
無症候性僧帽弁逆流症と大動脈弁逆流症の自然経過,
第105回日本循環器学会四国地方会, 2014年12月. 坂東左知子, 添木武, 今田久美子, 松本和久, 原知也, 高島啓, 山﨑宙, 坂東美佳, 齋藤友子, 松浦朋美, 伊勢孝之, 楠瀬賢也, 飛梅威, 山口浩司, 八木秀介, 岩瀬俊, 山田博胤, 若槻哲三, 佐田政隆 :
右室流出路心外膜起源が疑われた突発性心室期外収縮の一例,
第105回日本循環器学会四国地方会, 2014年12月. 稲垣太造, 八木秀介, 伊勢孝之, 山口浩司, 飛梅威, 岩瀬俊, 山田博胤, 添木武, 若槻哲三, 島袋充生, 赤池雅史, 佐田政隆 :
治療抵抗性本態性高血圧に対する利尿剤の効果-インダパミドが効果的であった2例の検討-,
第105回日本循環器学会四国地方会, 2014年12月. 富永真由, 伊勢孝之, 坂東美佳, 今田久美子, 松本和久, 高川由利子, 原知也, 齋藤友子, 高島啓, 山﨑宙, 坂東左知子, 松浦朋美, 飛梅威, 山口浩司, 八木秀介, 岩瀬俊, 山田博胤, 添木武, 若槻哲三, 坂東正章, 佐田政隆 :
超選択的コントラストエコーを併用し経皮的中隔心筋焼灼術を有効に施行し得た閉塞性肥大型心筋症の1例,
第105回日本循環器学会四国地方会, 2014年12月. 伊勢孝之, 岩瀬俊, 高川由利子, 楠瀬賢也, 山口浩司, 八木秀介, 山田博胤, 添木武, 若槻哲三, 佐田政隆 :
心臓サルコイドーシス再燃に対してメトトレキサートの併用が有効であった1例,
第111回日本内科学会四国地方会, 2014年11月. 松浦朋美, 添木武, 西條良仁, 齋藤友子, 高島啓, 坂東美佳, 坂東左知子, 發知淳子, 伊勢孝之, 飛梅威, 山口浩司, 八木秀介, 岩瀬俊, 山田博胤, 若槻哲三, 佐田政隆 :
筋強直性ジストロフィーに伴い二次性心筋症と心房頻拍を呈し，カテーテルアブレーションを施行した一例,
第62回日本心臓病学会学術集会, 2014年9月. 發知淳子, 山田博胤, 西條良仁, 坂東美佳, 高島啓, 伊勢孝之, 山口浩司, 八木秀介, 岩瀬俊, 添木武, 若槻哲三, 佐田政隆 :
薬剤抵抗性起立性調節障害に対する携帯型下肢陽圧装置の効果,
第62回日本心臓病学会学術集会, 2014年9月. 坂東左知子, 添木武, 飛梅威, 松浦朋美, 伊勢孝之, 山口浩司, 八木秀介, 岩瀬俊, 山田博胤, 若槻哲三, 佐田政隆 :
ATP 感受性リエントリー性心房頻拍の2症例,
第62回日本心臓病学会学術集会, 2014年9月. 原知也, 若槻哲三, 山口浩司, 伊勢孝之, 飛梅威, 八木秀介, 岩瀬俊, 山田博胤, 添木武, 佐田政隆 :
十分な術前ヘパリン置換にもかかわらず超遅発性ステント血栓症を発症した症例の検討-OCT による観察から-,
第62回日本心臓病学会学術集会, 2014年9月. 坂東美佳, 山田博胤, 西尾進, 林修司, 發知淳子, 西條良仁, 楠瀬賢也, 伊勢孝之, 山口浩司, 八木秀介, 岩瀬俊, 添木武, 若槻哲三, 佐田政隆 :
心房細動症例におけるCHADS2 およびCHA2DS2-VASc スコアと左心耳血流速度の関連,
第62回日本心臓病学会学術集会, 2014年9月. 添木武, 坂東左知子, 松浦朋美, 飛梅威, 高島啓, 坂東美佳, 發知淳子, 伊勢孝之, 山口浩司, 八木秀介, 福田大受, 岩瀬俊, 山田博胤, 若槻哲三, 島袋充生, 佐田政隆 :
心房細動におけるmicroRNAと心房リモデリングおよび予後との関係,
第62回日本心臓病学会学術集会, 2014年9月. 山口浩司, 若槻哲三, 伊勢孝之, 高島啓, 齋藤友子, 飛梅威, 岩瀬俊, 佐田政隆 :
第一世代薬剤溶出性ステントの超遅発性血栓症の2例-病歴・病変観察の観点から-,
第21回日本心血管インターベンション治療学会中国・四国地方会, 2014年9月. 高島啓, 若槻哲三, 山口浩司, 齋藤友子, 山﨑宙, 伊勢孝之, 飛梅威, 岩瀬俊, 佐田政隆 :
CTO治療後慢性期に形成された二重血行路をOCTで観察した一例,
第21回日本心血管インターベンション治療学会中国・四国地方会, 2014年9月. 富永真由, 伊勢孝之, 坂東美佳, 今田久美子, 松本和久, 高川由利子, 高木恵理, 西條良仁, 原知也, 齋藤友子, 高島啓, 山﨑宙, 坂東左知子, 松浦朋美, 發知淳子, 飛梅威, 山口浩司, 八木秀介, 岩瀬俊, 山田博胤, 添木武, 若槻哲三, 坂東正章, 佐田政隆 :
超選択的コントラストエコーを併用し経皮的中隔心筋焼灼術を有効に施行し得た閉塞性肥大型心筋症の一例,
第249回徳島医学会学術集会(平成26年度夏期), 2014年7月. 亀田香奈子, 伊勢孝之, 西條良仁, 今田久美子, 松本和久, 高川由利子, 高木恵理, 原知也, 齋藤友子, 高島啓, 山﨑宙, 坂東美佳, 坂東左知子, 松浦朋美, 發知淳子, 飛梅威, 山口浩司, 八木秀介, 岩瀬俊, 山田博胤, 添木武, 若槻哲三, 近藤剛, 佐田政隆 :
原発性アルドステロン症患者に高度冠攣縮を合併し心筋梗塞を発症した1症例,
第249回徳島医学会学術集会(平成26年度夏期), 2014年7月. 西川幸治, 石井亜由美, 後藤強, 伊勢孝之, 八木秀介, 岩瀬俊, 赤池雅史, 加藤真介, 佐田政隆 :
運動習慣の有無が運動耐用能および動脈機能の関係に及ぼす影響について,
第20回日本心臓リハビリテーション学会学術集会, 2014年7月. 石井亜由美, 八木秀介, 西川幸治, 後藤強, 伊勢孝之, 岩瀬俊, 赤池雅史, 加藤真介, 佐田政隆 :
心臓リハビリテーション実施期間中の体重増加が運動耐容能におよぼす影響,
第20回日本心臓リハビリテーション学会学術集会, 2014年7月. 西條良仁, 伊勢孝之, 三木浩和, 賀川久美子, 原知也, 齋藤友子, 高島啓, 坂東美佳, 坂東左知子, 松浦朋美, 發知淳子, 山口浩司, 飛梅威, 八木秀介, 岩瀬俊, 山田博胤, 添木武, 若槻哲三, 奥村宇信, 藤永裕之, 佐田政隆 :
高度心機能障害を伴う原発性心アミロイドーシスに対しauto-PBSCTを施行し得た一例,
第104回日本循環器学会中国・四国合同地方会, 2014年7月. 澤田直子, 高川由利子, 發知淳子, 西條良仁, 高島啓, 坂東美佳, 山崎宙, 坂東左知子, 松浦朋美, 伊勢孝之, 飛梅威, 山口浩司, 八木秀介, 岩瀬俊, 山田博胤, 添木武, 若槻哲三, 佐田政隆 :
心エコー検査による大動脈弁逆流の重症度判定が困難であった大動脈弁位生体弁機能不全の一例,
第104回日本循環器学会中国・四国合同地方会, 2014年7月. 原知也, 八木秀介, 伊勢孝之, 飛梅威, 山口浩司, 岩瀬俊, 山田博胤, 添木武, 若槻哲三, 佐田政隆 :
大動脈解離の急性期降圧療法における経皮吸収型β1遮断薬の使用経験,
第104回日本循環器学会中国・四国合同地方会, 2014年7月. 坂東左知子, 添木武, 飛梅威, 松浦朋美, 今田久美子, 松本和久, 高木恵理, 西條良仁, 原知也, 齋藤友子, 高島啓, 坂東美佳, 山崎宙, 伊勢孝之, 發知淳子, 山口浩司, 八木秀介, 岩瀬俊, 山田博胤, 若槻哲三, 佐田政隆 :
ATP感受性リエントリー性心房頻拍の一例,
第104回日本循環器学会中国・四国合同地方会, 2014年7月. 松浦朋美, 添木武, 松本和久, 今田久美子, 西條良仁, 高木恵理, 原知也, 齋藤友子, 高島啓, 坂東美佳, 山崎宙, 坂東左知子, 發知淳子, 伊勢孝之, 飛梅威, 山口浩司, 八木秀介, 岩瀬俊, 山田博胤, 若槻哲三, 佐田政隆 :
心房頻拍と心不全を契機に発覚した筋強直性ジストロフィーの一例,
第104回日本循環器学会中国・四国合同地方会, 2014年7月. 坂東左知子, 添木武, 飛梅威, 松浦朋美, 齋藤友子, 高島啓, 坂東美佳, 山崎宙, 伊勢孝之, 發知淳子, 山口浩司, 八木秀介, 岩瀬俊, 山田博胤, 若槻哲三, 阪田美穂, 早渕康信, 井上美紀, 森一博, 木下学, 佐田政隆 :
薬剤抵抗性特発性心室頻拍に対し，PCPS下にアブレーション治療を施行し，社会復帰に成功した若年例の一例,
第104回日本循環器学会中国・四国合同地方会, 2014年7月. 松本和久, 若槻哲三, 高島啓, 山口浩司, 西條良仁, 高木恵理, 原知也, 齋藤友子, 高川由利子, 山崎宙, 坂東美佳, 坂東左知子, 松浦朋美, 伊勢孝之, 發知淳子, 飛梅威, 八木秀介, 岩瀬俊, 山田博胤, 添木武, 佐田政隆 :
シロリムス溶出ステント留置7年後に初めて造影剤ステント周囲滲み出し像と局所凝固反応亢進を認めた一例,
第104回日本循環器学会中国・四国合同地方会, 2014年7月. 原知也, 若槻哲三, 山口浩司, 伊勢孝之, 飛梅威, 八木秀介, 岩瀬俊, 山田博胤, 添木武, 佐田政隆 :
十分な術前ヘパリン置換にもかかわらず超遅発性ステント血栓症を発症した症例-OCTによる観察からの検討-,
第104回日本循環器学会中国・四国合同地方会, 2014年7月. 今田久美子, 伊勢孝之, 原知也, 八木秀介, 岩瀬俊, 西條良仁, 小笠原梢, 高島啓, 坂東美佳, 坂東左知子, 松浦朋美, 發知淳子, 飛梅威, 山口浩司, 山田博胤, 添木武, 若槻哲三, 赤池雅史, 佐田政隆 :
心不全を合併した頻脈性心房細動にランジオロールを有効に使用することができた2症例,
第104回日本循環器学会中国・四国合同地方会, 2014年7月. 高川由利子, 八木秀介, 山田博胤, 林修司, 發知淳子, 坂東美佳, 山口浩司, 伊勢孝之, 飛梅威, 岩瀬俊, 添木武, 若槻哲三, 佐田政隆 :
母児ともに救命できた母児間輸血症候群と妊娠高血圧腎症に合併した急性心不全の一例,
第104回日本循環器学会中国・四国合同地方会, 2014年7月. 原知也, 伊勢孝之, 飛梅威, 山口浩司, 八木秀介, 岩瀬俊, 山田博胤, 添木武, 若槻哲三, 佐田政隆 :
Vascular endothelial growth factor (VEGF)阻害薬の眼内投与中に急性冠症候群を発症した4症例の検討,
第104回日本循環器学会中国・四国合同地方会, 2014年7月. 齋藤友子, 伊勢孝之, 發知淳子, 山口浩司, 岩瀬俊, 山田博胤, 添木武, 若槻哲三, 後東久嗣, 佐田政隆 :
左室収縮不全と間質性肺炎に伴う肺高血圧症を合併した皮膚筋炎の1例,
第110回日本内科学会四国地方会, 2014年6月. 齋藤友子, 伊勢孝之, 發知淳子, 山口浩司, 岩瀬俊, 山田博胤, 添木武, 若槻哲三, 佐田政隆, 後東久嗣 :
左室収縮不全と間質性肺炎に伴う肺高血圧症を合併した皮膚筋炎の1例,
第110回日本内科学会四国地方会, 2014年6月. 鳥居裕太, 西尾進, 山尾雅美, 平田有紀奈, 發知淳子, 伊勢孝之, 髙尾正一郎, 六車直樹, 山田博胤, 佐田政隆 :
門脈圧亢進症および門脈・左胃静脈内血栓による巨大脾動脈瘤の1症例,
第87回日本超音波医学会学術集会, 2014年5月. S Bando, Takeshi Soeki, T Matsuura, Takeshi Tobiume, T Hara, A Takashima, Mika Bando, K Ogasawara, Y Saito, Junko Hotsuchi, E Kimura, Takayuki Ise, Koji Yamaguchi, Shusuke Yagi, Takashi Iwase, Daiju Fukuda, Hirotsugu Yamada, Tetsuzo Wakatsuki, Michio Shimabukuro and Masataka Sata :
Atrial late potentials and atrial substrate remodeling in patients with atrial fibrillation.,
第78回日本循環器学会学術集会, Mar. 2014. S Bando, Takeshi Soeki, T Hara, A Takashima, Mika Bando, K Ogasawara, Y Saito, T Matsuura, Junko Hotsuchi, E Kimura, Takayuki Ise, Takeshi Tobiume, Koji Yamaguchi, Shusuke Yagi, Takashi Iwase, Daiju Fukuda, Hirotsugu Yamada, Tetsuzo Wakatsuki, Michio Shimabukuro, Kenji Kangawa and Masataka Sata :
Ghrelin ameliorates the progression of experimental autoimmune myocarditis.,
第78回日本循環器学会学術集会, Mar. 2014. Koji Yamaguchi, Tetsuzo Wakatsuki, T Hara, K Ogasawara, Mika Bando, A Takashima, S Bando, T Matsuura, Takayuki Ise, Junko Hotsuchi, Takeshi Tobiume, Shusuke Yagi, Takashi Iwase, Hirotsugu Yamada, Takeshi Soeki and Masataka Sata :
Differential responses of local coagulation after implantation of biolimus-eluting and everolimus-eluting stents compared with sirolimus-eluting and bare metal stents.,
第78回日本循環器学会学術集会, Mar. 2014. Mika Bando, Hirotsugu Yamada, S Nishio, Junko Hotsuchi, S Hayashi, E Kimura, Takayuki Ise, T Matsuura, Takeshi Tobiume, Koji Yamaguchi, Shusuke Yagi, Takashi Iwase, Takeshi Soeki, Tetsuzo Wakatsuki and Masataka Sata :
Parallel changes in sonographic characteristics of carotid and coronary plaques.,
第78回日本循環器学会学術集会, Mar. 2014. Takayuki Ise, Shusuke Yagi, Takashi Iwase, Masashi Akaike, A Takashima, Mika Bando, S Bando, T Matsuura, Junko Hotsuchi, Takeshi Tobiume, Koji Yamaguchi, Hirotsugu Yamada, Takeshi Soeki, Tetsuzo Wakatsuki and Masataka Sata :
Impact of cardiac rehabilitation on oxidized stress in patients with heart failure.,
第78回日本循環器学会学術集会, Mar. 2014. T Matsuura, Takeshi Soeki, R Ota, T Hara, Y Saito, K Ogasawara, A Takashima, Mika Bando, S Bando, Junko Hotsuchi, E Kimura, Takayuki Ise, Takeshi Tobiume, Koji Yamaguchi, Shusuke Yagi, Takashi Iwase, Hirotsugu Yamada, Tetsuzo Wakatsuki and Masataka Sata :
Increased local production of c-type natriuretic peptide in patients with vasospastic angina.,
第78回日本循環器学会学術集会, Mar. 2014. Takeshi Soeki, S Bando, T Matsuura, Takeshi Tobiume, T Hara, R Ota, A Takashima, Mika Bando, K Ogasawara, Y Saito, Takayuki Ise, Junko Hotsuchi, E Kimura, Koji Yamaguchi, Shusuke Yagi, Daiju Fukuda, Takashi Iwase, Hirotsugu Yamada, Tetsuzo Wakatsuki, Michio Shimabukuro and Masataka Sata :
Relationship between local production of microRNA-328 and atrial substrate remodeling in atrial fibrillation.,
第78回日本循環器学会学術集会, Mar. 2014. 今田久美子, 八木秀介, 山口浩司, 若槻哲三, 伊勢孝之, 太田理絵, 門田宗之, 高島啓, 松浦朋美, 飛梅威, 岩瀬俊, 山田博胤, 添木武, 赤池雅史, 佐田政隆 :
心不全を合併した腎血管性高血圧に対する経皮的腎動脈形成術の有効性,
第248回徳島医学会学術集会, 2014年2月. 松本和久, 高島啓, 山口浩司, 若槻哲三, 西條良仁, 高木恵理, 原知也, 齋藤友子, 小笠原梢, 坂東美佳, 坂東左知子, 松浦朋美, 伊勢孝之, 發知淳子, 木村恵理子, 飛梅威, 八木秀介, 岩瀬俊, 山田博胤, 添木武, 佐田政隆 :
シロリムス溶出ステント留置7年後に初めて造影剤ステント周囲滲み出し像を認めた一例,
第248回徳島医学会学術集会, 2014年2月. 八木秀介, 粟飯原賢一, 赤池雅史, 松本幸子, 福田大受, 松浦朋美, 伊勢孝之, 山口浩司, 岩瀬俊, 山田博胤, 添木武, 若槻哲三, 島袋充生, 松本俊夫, 佐田政隆 :
DPP-4阻害薬の血糖降下作用に対する有効性予測因子,
第248回徳島医学会学術集会, 2014年2月. 坂東左知子, 添木武, 飛梅威, 松浦朋美, 西條良仁, 高木恵理, 原知也, 小笠原梢, 坂東美佳, 齋藤友子, 高島啓, 發知淳子, 木村恵理子, 伊勢孝之, 山口浩司, 八木秀介, 岩瀬俊, 山田博胤, 若槻哲三, 坂東正章, 佐田政隆 :
Aorta-mitral continuityが起源の心房頻拍の一例,
第103回日本循環器学会四国地方会, 2013年12月. 發知淳子, 山田博胤, 原知也, 太田理絵, 高島啓, 坂東美佳, 小笠原梢, 坂東左知子, 松浦朋美, 伊勢孝之, 木村恵理子, 飛梅威, 山口浩司, 八木秀介, 岩瀬俊, 添木武, 若槻哲三, 赤池雅史, 佐田政隆 :
下肢陽圧負荷の効果があった薬剤抵抗性起立性低血圧の2症例,
第103回日本循環器学会四国地方会, 2013年12月. 高島啓, 八木秀介, 高木恵理, 木下肇, 神原保, 原知也, 太田理絵, 坂東美佳, 坂東左知子, 伊勢孝之, 松浦朋美, 發知淳子, 飛梅威, 山口浩司, 岩瀬俊, 山田博胤, 添木武, 若槻哲三, 木村建彦, 北川哲也, 佐田政隆 :
冠静脈洞に疣贅が認められた冠動静脈瘻を合併した感染性心内膜炎の一例,
第103回日本循環器学会四国地方会, 2013年12月. 生田奈央, 高島啓, 原知也, 伊勢孝之, 島袋充生, 西條良仁, 高木恵理, 太田理絵, 齋藤友子, 坂東美佳, 坂東左知子, 松浦朋美, 發知淳子, 飛梅威, 山口浩司, 八木秀介, 岩瀬俊, 山田博胤, 添木武, 若槻哲三, 佐田政隆 :
心身症として見過ごされてきた体位性起立頻脈症候群を的確に診断・治療し得た1例,
第103回日本循環器学会四国地方会, 2013年12月. 西條良仁, 松浦朋美, 飛梅威, 添木武, 坂東左知子, 高木恵理, 太田理絵, 原知也, 小笠原梢, 齋藤友子, 高島啓, 坂東美佳, 發知淳子, 木村恵理子, 伊勢孝之, 八木秀介, 岩瀬俊, 山田博胤, 若槻哲三, 佐田政隆 :
上位共通路の存在が示唆され室房ブロックを伴っても持続する2種類の房室結節リエントリー性頻拍を認めた1例,
第103回日本循環器学会四国地方会, 2013年12月. 坂東左知子, 飛梅威, 添木武, 松浦朋美, 西條良仁, 高木恵理, 原知也, 小笠原梢, 坂東美佳, 齋藤友子, 高島啓, 發知淳子, 木村恵理子, 伊勢孝之, 山口浩司, 八木秀介, 岩瀬俊, 山田博胤, 若槻哲三, 佐田政隆 :
AMI急性期のVT/VF stormに対しtriggered PVC ablation を施行した一例,
第103回日本循環器学会四国地方会, 2013年12月. 松浦朋美, 飛梅威, 添木武, 坂東左知子, 高木恵理, 西條良仁, 太田理絵, 原知也, 齋藤友子, 小笠原梢, 高島啓, 坂東美佳, 伊勢孝之, 發知淳子, 木村恵理子, 山口浩司, 八木秀介, 岩瀬俊, 山田博胤, 若槻哲三, 佐田政隆 :
ペースメーカー植込みの是非に検討を要した洞心不全症候群の一例,
第103回日本循環器学会四国地方会, 2013年12月. 石井亜由美, 西川幸治, 伊勢孝之, 八木秀介, 岩瀬俊, 門田宗之, 西條良仁, 高島啓, 松浦朋美, 發知淳子, 飛梅威, 山口浩司, 山田博胤, 添木武, 若槻哲三, 中山泰介, 赤池雅史, 加藤真介, 北川哲也, 佐田政隆 :
人工呼吸管理中の心不全症例に心臓リハビリテーションが有効に施行しえた症例,
第103回日本循環器学会四国地方会, 2013年12月. 伊勢孝之, 八木秀介, 岩瀬俊, 西條良仁, 高木恵理, 太田理絵, 門田宗之, 原知也, 小笠原梢, 高島啓, 坂東美佳, 坂東左知子, 松浦朋美, 發知淳子, 飛梅威, 山口浩司, 山田博胤, 添木武, 若槻哲三, 赤池雅史, 佐田政隆 :
当院でのAdaptive-Servo Ventilationが有効であった拡張障害心不全の症例検討,
第103回日本循環器学会四国地方会, 2013年12月. 小笠原梢, 伊勢孝之, 山口浩司, 岩瀬俊, 山田博胤, 添木武, 若槻哲三, 佐田政隆 :
Fallot四徴症に対する根治術施行30年後に左心不全を合併した1例,
第109回日本内科学会四国地方会, 2013年12月. 玉置俊輔, 原知也, 伊勢孝之, 山口浩司, 八木秀介, 岩瀬俊, 山田博胤, 添木武, 若槻哲三, 佐田政隆 :
冠攣縮および器質的冠狭窄を合併したBuerger病の1例,
第109回日本内科学会四国地方会, 2013年12月. Takayuki Ise, Takashi Iwase, Hirotsugu Yamada, Shusuke Yagi, Takeshi Tobiume, Koji Yamaguchi, Takeshi Soeki, Tetsuzo Wakatsuki, Masashi Akaike and Masataka Sata :
Progression of a Case of Myocardial Damage Caused by Beckers Muscular Dystrophy.,
第17回日本心不全学会学術集会, Nov. 2013. 鳥居裕太, 西尾進, 山尾雅美, 平田有紀奈, 笹田倫子, 伊勢孝之, 髙尾正一郎, 六車直樹, 山田博胤, 佐田政隆 :
巨大脾動脈瘤の1症例,
第23回日本超音波医学会四国地方会学術集会, 2013年10月. 太田理絵, 今田久美子, 八木秀介, 坂東左知子, 松浦朋美, 伊勢孝之, 發知淳子, 上田由佳, 飛梅威, 山口浩司, 岩瀬俊, 山田博胤, 添木武, 若槻哲三, 佐田政隆 :
冠灌流域に合致しない心電図誘導にJ波を認めた急性冠症候群の一例,
第61回日本心臓病学会学術集会, 2013年9月. 太田理絵, 今田久美子, 八木秀介, 坂東左知子, 松浦朋美, 伊勢孝之, 發知淳子, 上田由佳, 飛梅威, 山口浩司, 岩瀬俊, 山田博胤, 添木武, 若槻哲三, 佐田政隆 :
経皮的腎動脈形成術により難治性心不全が改善した両側腎動脈狭窄症の1例,
第61回日本心臓病学会学術集会, 2013年9月. 門田宗之, 伊勢孝之, 八木秀介, 岩瀬俊, 赤池雅史, 原知也, 太田理絵, 坂東美佳, 高島啓, 坂東左知子, 松浦朋美, 山口浩司, 山田博胤, 添木武, 若槻哲三, 佐田政隆 :
慢性心不全患者に対するトルバプタン投与における薬物血中濃度と利尿効果の検討,
第61回日本心臓病学会学術集会, 2013年9月. 伊勢孝之, 岩瀬俊, 赤池雅史, 西尾進, 山口浩司, 山田博胤, 添木武, 若槻哲三, 佐田政隆 :
Intramural Hematoma症例のUlcer Like Projection形成と拡大における穿通枝の重要性,
第61回日本心臓病学会学術集会, 2013年9月. 伊勢孝之, 岩瀬俊, 山田博胤, 坂東美佳, 西尾進, 山口浩司, 添木武, 若槻哲三, 赤池雅史, 佐田政隆 :
Becker型筋ジストロフィーによる心筋障害の経過を観察し得た1例,
第61回日本心臓病学会学術集会, 2013年9月. 岩瀬俊, 髙尾正一郎, 太田理絵, 山口浩司, 赤池雅史, 伊勢孝之, 山田博胤, 添木武, 若槻哲三, 原田雅史, 佐田政隆 :
3ステラ非造影心臓MRI検査が左室内壁在血栓の検出ならびに治療方針決定に有用であった無症候性心筋虚血の1例,
第61回日本心臓病学会学術集会, 2013年9月. 岩瀬俊, 髙尾正一郎, 赤池雅史, 伊勢孝之, 八木秀介, 山口浩司, 山田博胤, 添木武, 若槻哲三, 西岡安彦, 原田雅史, 佐田政隆 :
左室収縮不全を伴う心サルコイドーシスと他の心疾患鑑別におけるガドリニウム遅延造影定量評価の有用性,
第61回日本心臓病学会学術集会, 2013年9月. 平田有紀奈, 山田博胤, 西尾進, 真鍋泰毅, 友藤達陽, 天野里江, 鳥居裕太, 山尾雅美, 坂東美佳, 林修司, 伊勢孝之, 山口浩司, 岩瀬俊, 添木武, 若槻哲三, 佐田政隆 :
冠動脈硬化症と各種脂肪厚との関連∼超音波検査を用いた検討∼,
第61回日本心臓病学会学術集会, 2013年9月. 山口浩司, 若槻哲三, 坂東美佳, 高島啓, 伊勢孝之, 岩瀬俊, 山田博胤, 添木武, 佐田政隆 :
Everolimus-eluting stent留置後における局所凝固反応とステント長の関連性,
第61回日本心臓病学会学術集会, 2013年9月. 安岡紗哉香, 山田博胤, 坂東美佳, 林修司, 西尾進, 天野里江, 平田有紀奈, 横倉航一, 伊勢孝之, 山口浩司, 岩瀬俊, 添木武, 若槻哲三, 佐田政隆 :
たこつぼ型心筋症の予後と回復過程に関する検討,
第61回日本心臓病学会学術集会, 2013年9月. 林修司, 山田博胤, 西尾進, 坂東美佳, 平田有紀奈, 伊勢孝之, 山口浩司, 岩瀬俊, 添木武, 若槻哲三, 佐田政隆 :
冠動脈疾患におけるAugmentation indexの臨床的有用性についての検討,
第61回日本心臓病学会学術集会, 2013年9月. 若槻哲三, 山口浩司, 伊勢孝之, 八木秀介, 岩瀬俊, 山田博胤, 添木武, 佐田政隆 :
OCTにてmicrochannel構造を認める冠動脈プラークの局所炎症性の評価,
第61回日本心臓病学会学術集会, 2013年9月. 添木武, 坂東左知子, 松浦朋美, 高島啓, 坂東美佳, 發知淳子, 伊勢孝之, 飛梅威, 山口浩司, 八木秀介, 福田大受, 岩瀬俊, 山田博胤, 若槻哲三, 島袋充生, 佐田政隆 :
心房細動におけるPentraxin3と心房リモデリングおよび予後との関係,
第61回日本心臓病学会学術集会, 2013年9月. 坂東左知子, 添木武, 植松悦子, 松浦朋美, 伊勢孝之, 發知淳子, 飛梅威, 山口浩司, 八木秀介, 岩瀬俊, 福田大受, 山田博胤, 若槻哲三, 島袋充生, 寒川賢治, 佐田政隆 :
自己免疫性心筋炎に対するグレリンの効果,
第61回日本心臓病学会学術集会, 2013年9月. 西尾進, 山田博胤, 平田有紀奈, 鳥居裕太, 天野里江, 山尾雅美, 真鍋泰毅, 友藤達陽, 坂東美佳, 林修司, 伊勢孝之, 山口浩司, 岩瀬俊, 添木武, 若槻哲三, 佐田政隆 :
各種血管機能検査指標における性差の影響,
第61回日本心臓病学会学術集会, 2013年9月. 今田久美子, 太田理絵, 八木秀介, 山口浩司, 若槻哲三, 岩瀬俊, 西條良仁, 高木恵理, 門田宗之, 原知也, 齋藤友子, 高島啓, 坂東美佳, 坂東左知子, 松浦朋美, 伊勢孝之, 發知淳子, 飛梅威, 山田博胤, 添木武, 佐田政隆, 春藤譲冶 :
経皮的腎動脈形成術により難治性心不全が改善したCardiac disturbance syndromeの1例,
第247回徳島医学会学術集会, 2013年8月. 生田奈央, 高島啓, 原知也, 伊勢孝之, 西條良仁, 高木恵理, 門田宗之, 太田理絵, 齋藤友子, 坂東美佳, 坂東左知子, 松浦朋美, 發知淳子, 飛梅威, 山口浩司, 八木秀介, 岩瀬俊, 山田博胤, 添木武, 若槻哲三, 佐田政隆, 島袋充生, 福田大受, 友竹正人 :
心身症として見過ごされていた体位性起立頻脈症候群を的確に診断・治療し得た一例,
第247回徳島医学会学術集会, 2013年8月. 門田宗之, 伊勢孝之, 八木秀介, 岩瀬俊, 太田理絵, 原知也, 高島啓, 坂東美佳, 坂東左知子, 松浦朋美, 發知淳子, 飛梅威, 山口浩司, 山田博胤, 添木武, 若槻哲三, 佐田政隆, 赤池雅史 :
慢性心不全における新規利尿薬tolvaptanの効果予測因子,
第247回徳島医学会学術集会, 2013年8月. 石井亜由美, 西川幸治, 加藤真介, 伊勢孝之, 八木秀介, 岩瀬俊, 上田由佳, 門田宗之, 高島啓, 飛梅威, 山口浩司, 山田博胤, 添木武, 若槻哲三, 佐田政隆, 中川泰介, 北川哲也, 赤池雅史 :
人工呼吸管理中に心臓リハビリを有効に施行しえた開心術後の心不全症例,
第247回徳島医学会学術集会, 2013年8月. 西條良仁, 松浦朋美, 飛梅威, 添木武, 坂東左知子, 高木恵理, 太田理絵, 門田宗之, 原知也, 齋藤友子, 高島啓, 坂東美佳, 伊勢孝之, 發知淳子, 山口浩司, 八木秀介, 岩瀬俊, 山田博胤, 若槻哲三, 佐田政隆, 三木延茂 :
室房ブロックを伴っても持続する2種類の房室結節リエントリー性頻拍を認め，上位共通路の存在が示唆された1例,
第247回徳島医学会学術集会, 2013年8月. 太田理絵, 八木秀介, 若槻哲三, 岩瀬俊, 西條良仁, 高木恵理, 門田宗之, 原知也, 齋藤友子, 高島啓, 坂東美佳, 坂東左知子, 松浦朋美, 伊勢孝之, 發知淳子, 飛梅威, 山口浩司, 山田博胤, 添木武, 佐田政隆, 今田久美子, 髙尾正一郎 :
急性期の心電図でJ波を認めた急性心筋梗塞の一例,
第247回徳島医学会学術集会, 2013年8月. 八木秀介, 發知淳子, 山田博胤, 岩瀬俊, 伊勢孝之, 山口浩司, 添木武, 若槻哲三, 佐田政隆, 近藤剛史 :
高血圧・糖尿病・脂質異常症・脳心血管障害を合併した原発性副甲状腺機能亢進症の1例,
日本内科学会第108回四国地方会, 2013年6月. 平田有紀奈, 西尾進, 山田博胤, 發知淳子, 坂東美佳, 林修司, 冨田紀子, 伊勢孝之, 仁木敏之, 山口浩司, 八木秀介, 竹谷善雄, 岩瀬俊, 添木武, 若槻哲三, 佐田政隆 :
冠動脈狭窄と関連する脂肪組織はどれか?∼超音波検査を用いた検討∼,
第102回日本循環器学会中国・四国合同地方会, 2013年5月. 西尾進, 山田博胤, 發知淳子, 平田有紀奈, 坂東美佳, 林修司, 冨田紀子, 伊勢孝之, 仁木敏之, 山口浩司, 八木秀介, 竹谷善雄, 岩瀬俊, 添木武, 若槻哲三, 佐田政隆 :
高血圧患者の腎末梢血管抵抗に対するイルベサルタンの効果,
第102回日本循環器学会中国・四国合同地方会, 2013年5月. 原知也, 門田宗之, 川端豊, 太田理絵, 高島啓, 坂東美佳, 坂東左知子, 松浦朋美, 上田由佳, 冨田紀子, 伊勢孝之, 仁木敏之, 山口浩司, 八木秀介, 竹谷善雄, 岩瀬俊, 山田博胤, 添木武, 若槻哲三, 佐田政隆 :
スピロノラクトンを中心とした薬物療法で30年間経過を観察しえたが，病勢制御困難となり手術療法を要したアルドステロン産生腺腫の一例,
第102回日本循環器学会中国・四国合同地方会, 2013年5月. 幸田舞子, 伊勢孝之, 川端豊, 門田宗之, 原知也, 太田理絵, 坂東美佳, 坂東左知子, 松浦朋美, 仁木敏之, 發知淳子, 山口浩司, 八木秀介, 岩瀬俊, 竹谷善雄, 山田博胤, 赤池雅史, 林友鴻, 長谷川拓也, 佐田政隆 :
経皮的中隔心筋焼灼術が奏功した閉塞性肥大型心筋症の1例,
第102回日本循環器学会中国・四国合同地方会, 2013年5月. 太田理絵, 山口浩司, 門田宗之, 川端豊, 原知也, 高島啓, 坂東美佳, 坂東左知子, 松浦朋美, 伊勢孝之, 仁木敏之, 上田由佳, 八木秀介, 岩瀬俊, 竹谷善雄, 山田博胤, 添木武, 若槻哲三, 佐田政隆 :
治療方針に苦慮したDIC・多臓器不全合併コレステロール血晶塞栓症の一例,
第102回日本循環器学会中国・四国合同地方会, 2013年5月. 太田理絵, 山口浩司, 門田宗之, 川端豊, 原知也, 高島啓, 坂東美佳, 坂東左知子, 松浦朋美, 伊勢孝之, 仁木敏之, 上田由佳, 八木秀介, 岩瀬俊, 竹谷善雄, 山田博胤, 添木武, 若槻哲三, 坂東正章, 佐田政隆 :
治療方法選択に難渋した肺動静脈瘻合併右肺動脈上行大動脈起始症の一例,
第102回日本循環器学会中国・四国合同地方会, 2013年5月. 羽星辰哉, 門田宗之, 發知淳子, 竹谷善雄, 神原保, 川端豊, 原知也, 高島啓, 坂東美佳, 坂東左知子, 松浦朋美, 伊勢孝之, 仁木敏之, 山口浩司, 八木秀介, 岩瀬俊, 山田博胤, 添木武, 若槻哲三, 北川哲也, 佐田政隆 :
プロテインC欠損に心房細動および低左心機能を合併した左室・右房内血栓の一例,
第102回日本循環器学会中国・四国合同地方会, 2013年5月. 門田宗之, 伊勢孝之, 八木秀介, 岩瀬俊, 太田理絵, 小笠原梢, 川端豊, 原知也, 坂東美佳, 坂東左知子, 松浦朋美, 發知淳子, 仁木敏之, 山口浩司, 竹谷善雄, 山田博胤, 添木武, 若槻哲三, 佐田政隆 :
トルバプタンが効果を示したEisenmenger症候群に伴う高度右心不全の一例,
第102回日本循環器学会中国・四国合同地方会, 2013年5月. 高木恵理, 太田理絵, 仁木敏之, 門田宗之, 川端豊, 原知也, 高島啓, 坂東美佳, 坂東左知子, 松浦朋美, 伊勢孝之, 上田由佳, 山口浩司, 八木秀介, 岩瀬俊, 竹谷善雄, 山田博胤, 添木武, 若槻哲三, 佐田政隆 :
妊娠中に静脈血栓症を発症し診断されたATⅢ欠損症合併妊娠の一例,
第102回日本循環器学会中国・四国合同地方会, 2013年5月. 山中森晶, 坂東左知子, 山口浩司, 西尾進, 太田理絵, 添木武, 松浦朋美, 門田宗之, 川端豊, 原知也, 高島啓, 坂東美佳, 伊勢孝之, 仁木敏之, 發知淳子, 上田由佳, 冨田紀子, 山口浩司, 八木秀介, 岩瀬俊, 竹谷善雄, 山田博胤, 若槻哲三, 四宮秀美, 佐田政隆 :
永久ペースメーカー植え込み後に偶発的に見つかった内頸静脈血栓の一例,
第102回日本循環器学会中国・四国合同地方会, 2013年5月. 高島啓, 島袋充生, 田端実, 植田初江, 植松悦子, 太田理絵, 門田宗之, 川端豊, 原知也, 坂東美佳, 坂東左知子, 松浦朋美, 仁木敏之, 伊勢孝之, 發知淳子, 上田由佳, 冨田紀子, 山口浩司, 福田大受, 八木秀介, 竹谷善雄, 岩瀬俊, 山田博胤, 添木武, 若槻哲三, 高梨秀一郎, 佐田政隆 :
冠動脈内ステント内再狭窄4症例の病理組織学的検討,
第102回日本循環器学会中国・四国合同地方会, 2013年5月. 伊勢孝之, 岩瀬俊, 山田博胤, 川端豊, 門田宗之, 仁木敏之, 坂東美佳, 坂東左知子, 松浦朋美, 山口浩司, 八木秀介, 竹谷善雄, 添木武, 若槻哲三, 赤池雅史, 佐田政隆 :
心病変の経過を観察し得たBecker型筋ジストロフィーによる心不全の1例,
第102回日本循環器学会中国・四国合同地方会, 2013年5月. 坂東左知子, 添木武, 門田宗之, 川端豊, 原知也, 高島啓, 坂東美佳, 松浦朋美, 伊勢孝之, 仁木敏之, 發知淳子, 上田由佳, 山口浩司, 八木秀介, 岩瀬俊, 竹谷善雄, 山田博胤, 若槻哲三, 石本武男, 佐田政隆 :
AVN dual pathwayにより頻拍周期が一心拍ごとに変化下Orthodromic AVRTの一例,
第102回日本循環器学会中国・四国合同地方会, 2013年5月. 松浦朋美, 添木武, 伊勢孝之, 仁木敏之, 發知淳子, 上田由佳, 冨田紀子, 山口浩司, 八木秀介, 竹谷善雄, 岩瀬俊, 山田博胤, 若槻哲三, 佐田政隆 :
通電により電動特性が変化した副伝導路の一例,
第102回日本循環器学会中国・四国合同地方会, 2013年5月. 發知淳子, 山田博胤, 西尾進, 坂東美佳, 林修司, 冨田紀子, 太田理絵, 門田宗之, 川端豊, 原知也, 高島啓, 坂東左知子, 松浦朋美, 伊勢孝之, 仁木敏之, 上田由佳, 山口浩司, 八木秀介, 竹谷善雄, 岩瀬俊, 添木武, 若槻哲三, 佐田政隆 :
運動誘発性肺高血圧を有する膠原病例における右室機能の検討,
第102回日本循環器学会中国・四国合同地方会, 2013年5月. 伊勢孝之, 八木秀介, 岩瀬俊, 門田宗之, 仁木敏之, 坂東美佳, 坂東左知子, 松浦朋美, 山口浩司, 竹谷善雄, 山田博胤, 添木武, 若槻哲三, 赤池雅史, 佐田政隆 :
慢性心不全におけるAdaptive-Servo Ventilationの血行動態に対する効果,
第102回日本循環器学会中国・四国合同地方会, 2013年5月. T Matsuura, Takeshi Soeki, S Bando, T Hara, M Kadota, Y Kawabata, Mika Bando, J Hotchi, N Tomita, Yuka Ueda, Toshiyuki Niki, Takayuki Ise, Koji Yamaguchi, Shusuke Yagi, Daiju Fukuda, Yoshio Taketani, Takashi Iwase, Hirotsugu Yamada, Tetsuzo Wakatsuki, Michio Shimabukuro and Masataka Sata :
A Renin Inhibitor Prevents Atrial Endocardial Dysfunction in Rapidly Paced Rats with Streptozotocin-induced Diabetes.,
第77回日本循環器学会学術集会, Mar. 2013. Takayuki Ise, Shusuke Yagi, Masashi Akaike, Takashi Iwase, M Kadota, R Ota, Y Kawabata, T Hara, K Ogasawara, Mika Bando, S Bando, T Matsuura, Toshiyuki Niki, J Hotchi, Koji Yamaguchi, Yoshio Taketani, Hirotsugu Yamada, Takeshi Soeki, Tetsuzo Wakatsuki and Masataka Sata :
Adaptive Servo-Ventilation Improves Symptoms and Hemodynamics in Both Patients with Systolic and Diastolic Heart Failure.,
第77回日本循環器学会学術集会, Mar. 2013. Koji Yamaguchi, Takeshi Soeki, Tetsuzo Wakatsuki, Toshiyuki Niki, Yoshio Taketani, R Ota, M Kadota, Y Kawabata, T Hara, Mika Bando, S Bando, T Matsuura, Takayuki Ise, J Hotchi, Yuka Ueda, Takashi Iwase, N Tomita, Hirotsugu Yamada and Masataka Sata :
Impact of Indoxyl Sulfate, a Uremic Toxin, on Non-Culprit Coronary Plaque Composition Assessed by Integrated Backscatter Intravascular Ultrasound.,
第77回日本循環器学会学術集会, Mar. 2013. Takayuki Ise, Takashi Iwase, Shoichiro Takao, M Kadota, Mika Bando, S Bando, T Matsuura, Toshiyuki Niki, J Hotchi, Shusuke Yagi, Koji Yamaguchi, Yoshio Taketani, Hirotsugu Yamada, Takeshi Soeki, Tetsuzo Wakatsuki, Masashi Akaike, Masafumi Harada and Masataka Sata :
Evaluation of Right Ventricular Hypertrophy by Cardiac Magnetic Resonance is Useful for Detecting Cardiac Amyloidosis.,
第77回日本循環器学会学術集会, Mar. 2013. Koji Yamaguchi, Tetsuzo Wakatsuki, Toshiyuki Niki, Yoshio Taketani, R Ota, M Kadota, Y Kawabata, T Hara, Mika Bando, S Bando, T Matsuura, Takayuki Ise, J Hotchi, Yuka Ueda, Takashi Iwase, N Tomita, Hirotsugu Yamada, Takeshi Soeki and Masataka Sata :
Differential Responses of Local Coagulation after Implantation of Everolimus-Eluting Stent Compared with Early-Generation Drug-Eluting Stents.,
第77回日本循環器学会学術集会, Mar. 2013. Shusuke Yagi, Takayuki Ise, Hirotsugu Yamada, S Nishio, Yuka Ueda, Takashi Iwase, Toshiyuki Niki, Koji Yamaguchi, Yoshio Taketani, Takeshi Soeki, Tetsuzo Wakatsuki, Masashi Akaike and Masataka Sata :
Ratio of Eicosapentaenoic Acid to Arachidonic Acid is a Predictive Factor of Albuminuria and Endothelial Function in Patients with Dyslipidemia.,
第77回日本循環器学会学術集会, Mar. 2013. Takashi Iwase, Shoichiro Takao, Masashi Akaike, Takayuki Ise, Toshiyuki Niki, Yuka Ueda, Koji Yamaguchi, Yoshio Taketani, Hirotsugu Yamada, Takeshi Soeki, Ken-ichi Aihara, Tetsuzo Wakatsuki, Yasuhiko Nishioka, Masafumi Harada and Masataka Sata :
Differentiation of Left Ventricular Systolic Dysfunction Related to Cardiac Sarcoidosis and Other Heart Diseases Using contrast-enhanced Cardiovascular Magnetic Resonance.,
第77回日本循環器学会学術集会, Mar. 2013. M Kadota, Takayuki Ise, Shusuke Yagi, Takashi Iwase, Masashi Akaike, R Ota, Y Kawabata, T Hara, K Ogasawara, Mika Bando, S Bando, T Matsuura, Toshiyuki Niki, J Hotchi, Koji Yamaguchi, Yoshio Taketani, Hirotsugu Yamada, Takeshi Soeki, Tetsuzo Wakatsuki and Masataka Sata :
Effects of Tolvaptan are Predicted by Vasopressin/Aldosterone Ratio and Urine Osmolality in Patients with Chronic Heart Failure.,
第77回日本循環器学会学術集会, Mar. 2013. Toshiyuki Niki, Tetsuzo Wakatsuki, Mika Bando, Koji Yamaguchi, Yoshio Taketani, R Ota, Y Kawabata, M Kadota, T Hara, Mika Bando, Takayuki Ise, T Matsuura, Takashi Iwase, Hirotsugu Yamada, Takeshi Soeki and Masataka Sata :
Effects of Additional Eicosapentaenoic Acid Therapy on Inflammatory Cytokines and Atherosclerotic Plaque Component Assessed by Integrated Backscatter Ultrasound Systems.,
第77回日本循環器学会学術集会, Mar. 2013. 添木武, S Bando, T Matsuura, T Hara, R Ota, Y Kawabata, 坂東美佳, J Hotchi, N Tomita, 上田由佳, 仁木敏之, 伊勢孝之, 山口浩司, 八木秀介, 福田大受, 竹谷善雄, 岩瀬俊, 山田博胤, 若槻哲三, 島袋充生, 佐田政隆 :
Pentraxin 3 is a Local Inflammatory Marker in Atrial Fibrillation.,
第77回日本循環器学会学術集会, 2013年3月. Mika Bando, Hirotsugu Yamada, S Nishio, N Tomita, J Hotchi, S Hayashi, K Ogasawara, A Takashima, S Bando, Takayuki Ise, Toshiyuki Niki, T Matsuura, Yuka Ueda, Koji Yamaguchi, Shusuke Yagi, Takashi Iwase, Yoshio Taketani, Takeshi Soeki, Tetsuzo Wakatsuki and Masataka Sata :
Effect of Eicosapentaenoic Acid on the Stabilization of Vulnerability in Carotid Artery Plaque: Evaluation Using iPlaque® Software.,
第77回日本循環器学会学術集会, Mar. 2013. S Bando, Daiju Fukuda, Takeshi Soeki, E Uematsu, H Sato, A Takashima, Mika Bando, T Matsuura, Toshiyuki Niki, Takayuki Ise, J Hotchi, Yuka Ueda, N Tomita, Koji Yamaguchi, Yoshio Taketani, Takashi Iwase, Shusuke Yagi, Hirotsugu Yamada, Tetsuzo Wakatsuki, Michio Shimabukuro and Masataka Sata :
Relationship between NLRP3 Inflammasome Activation in Adipose Tissue and Atherosclerosis.,
第77回日本循環器学会学術集会, Mar. 2013. Takeshi Soeki, Koji Yamaguchi, Toshiyuki Niki, R Ota, T Hara, M Kadota, Mika Bando, S Bando, T Matsuura, J Hotchi, N Tomita, Yuka Ueda, Takayuki Ise, Shusuke Yagi, Daiju Fukuda, Yoshio Taketani, Takashi Iwase, Hirotsugu Yamada, Tetsuzo Wakatsuki, Michio Shimabukuro and Masataka Sata :
Cardiospecific microRNA Plasma Levels are Associated With Coronary Plaque Vulnerability.,
第77回日本循環器学会学術集会, Mar. 2013. E Takagi, R Ota, 仁木敏之, M Kadota, Y Kawabata, T Hara, A Takashima, 坂東美佳, S Bando, T Matsuura, 伊勢孝之, J Hotchi, 上田由佳, 山口浩司, 八木秀介, 岩瀬俊, 竹谷善雄, N Tomita, 山田博胤, 添木武, 若槻哲三, 佐田政隆, 中山聡一朗, 前田和寿, 苛原稔 :
妊娠を契機にATⅢ欠損症と診断され，血栓管理の後に出産に至った一例,
第246回徳島医学会学術集会(平成24年度冬期), 2013年2月. T Haboshi, M Kadota, J Hotchi, 竹谷善雄, T Matsuura, 伊勢孝之, 仁木敏之, 山口浩司, 八木秀介, 岩瀬俊, 山田博胤, 添木武, 若槻哲三, 佐田政隆, 木下肇, 神原保, 北川哲也, 古本博孝, 髙橋久弥 :
プロテインC欠損に心房細動および低左心機能を合併した左室・右房内血栓の一例,
第246回徳島医学会学術集会(平成24年度冬期), 2013年2月. S Sakamoto, M Kadota, 伊勢孝之, 岩瀬俊, S Bando, T Matsuura, 仁木敏之, J Hotchi, N Tomita, 上田由佳, 山口浩司, 八木秀介, 竹谷善雄, 山田博胤, 添木武, 若槻哲三, 佐田政隆, 赤池雅史, M Takeuchi :
再熱と寛解を繰り返す特発性心膜炎に対しイブプロフェンが有効であった1例,
第246回徳島医学会学術集会(平成24年度冬期), 2013年2月. K Ota, 仁木敏之, R Ota, Y Kawabata, M Kadota, T Hara, A Takashima, 坂東美佳, S Bando, T Matsuura, 伊勢孝之, J Hotchi, 上田由佳, 山口浩司, 八木秀介, 岩瀬俊, 竹谷善雄, N Tomita, 山田博胤, 添木武, 若槻哲三, 佐田政隆, J Shunto :
偶発的に発見された末梢動脈閉塞の二例,
第246回徳島医学会学術集会(平成24年度冬期), 2013年2月. M Koda, 佐田政隆, 伊勢孝之, Y Kawabata, 岩瀬俊, M Kadota, T Hara, R Ota, 坂東美佳, S Bando, T Matsuura, 仁木敏之, J Hotchi, N Tomita, 上田由佳, 山口浩司, 八木秀介, 竹谷善雄, 山田博胤, 添木武, 若槻哲三, 赤池雅史, S Okazaki, 林友鴻, T Hasegawa :
難治性の閉塞性肥大型心筋症に対して経皮的中隔心筋焼灼術が著効した1例,
第246回徳島医学会学術集会(平成24年度冬期), 2013年2月. R Ota, 山口浩司, M Kadota, Y Kawabata, T Hara, A Takashima, 坂東美佳, S Bando, T Matsuura, 伊勢孝之, 仁木敏之, J Hotchi, 上田由佳, 八木秀介, 岩瀬俊, 竹谷善雄, N Tomita, 山田博胤, 添木武, 若槻哲三, 佐田政隆, 髙尾正一郎, 原田雅史, M Bando :
41歳まで無症状で経過した肺動静脈瘻合併右肺動脈上行大動脈起始症の一例,
第246回徳島医学会学術集会(平成24年度冬期), 2013年2月. 坂東美佳, 山田博胤, S Nishio, R Tamai, Y Hirata, N Tomita, J Hotchi, S Hayashi, M Nakagawa, D Hirota, A Takashima, 伊勢孝之, 仁木敏之, 山口浩司, 福田大受, 八木秀介, 岩瀬俊, 竹谷善雄, 添木武, 若槻哲三, 佐田政隆 :
イコサペント酸エチルは頸動脈プラークの安定化に寄与する:iPlaque®を用いた検討,
第101回日本循環器学会四国地方会, 2012年12月. 上田由佳, 伊勢孝之, 岩瀬俊, K Maeda, K Nishikawa, M Kadota, T Hara, Y Kawabata, R Ota, 仁木敏之, 山口浩司, 八木秀介, 竹谷善雄, 山田博胤, 添木武, 若槻哲三, 赤池雅史, 加藤真介, 安井夏生, 佐田政隆 :
心臓リハビリテーションにおける禁煙継続効果の検討,
第101回日本循環器学会四国地方会, 2012年12月. Y Kawabata, 伊勢孝之, T Matsuura, S Bando, 岩瀬俊, K Ogasawara, 坂東美佳, 仁木敏之, J Hotchi, N Tomita, 上田由佳, 山口浩司, 八木秀介, 竹谷善雄, 山田博胤, 添木武, 若槻哲三, 赤池雅史, 佐田政隆 :
高度肥満を伴った拡張型心筋症の1例,
第101回日本循環器学会四国地方会, 2012年12月. R Ota, 仁木敏之, 竹谷善雄, M Kadota, Y Kawabata, T Hara, 坂東美佳, S Bando, T Matsuura, 伊勢孝之, J Hotchi, 上田由佳, 山口浩司, 岩瀬俊, N Tomita, 山田博胤, 添木武, 若槻哲三, 佐田政隆 :
カテーテル的血栓吸引・血栓溶解療法が奏功し，心肺停止状態から救命できた院内発症急性肺血栓塞栓症の一例,
第101回日本循環器学会四国地方会, 2012年12月. M Nakagawa, 山田博胤, S Nishio, N Tomita, J Hotchi, S Hayashi, 坂東美佳, R Tamai, Y Hirata, D Hirota, S Yasuoka, K Yokokura, 仁木敏之, 伊勢孝之, 山口浩司, 岩瀬俊, 竹谷善雄, 添木武, 若槻哲三, 佐田政隆 :
心房細動例における拡張中期僧帽弁口血流速波高は左室充満圧を反映する,
第101回日本循環器学会四国地方会, 2012年12月. S Sakamoto, M Kadota, 伊勢孝之, 岩瀬俊, S Bando, T Matsuura, 仁木敏之, J Hotchi, N Tomita, 上田由佳, 山口浩司, 八木秀介, 竹谷善雄, 山田博胤, 添木武, 若槻哲三, 赤池雅史, 佐田政隆 :
再燃と寛解を繰り返す特発性心膜炎に対しイブプロフェンが有効であった1例,
第101回日本循環器学会四国地方会, 2012年12月. N Kobayashi, T Hara, 山口浩司, K Ogasawara, 坂東美佳, S Bando, T Matsuura, J Hotchi, N Tomita, 伊勢孝之, 仁木敏之, 上田由佳, 竹谷善雄, 岩瀬俊, 山田博胤, 添木武, 若槻哲三, M Bando, 佐田政隆 :
多彩な血圧変動素因により顕著な夜間血圧を認めた一例,
第101回日本循環器学会四国地方会, 2012年12月. S Yasuoka, 山田博胤, K Yokokura, Y Hirata, D Hirota, R Tamai, M Nakagawa, S Nishio, 坂東美佳, J Hotchi, S Hayashi, N Tomita, 伊勢孝之, 仁木敏之, 山口浩司, 岩瀬俊, 竹谷善雄, 添木武, 若槻哲三, 佐田政隆 :
当院におけるたこつぼ型心筋症の臨床的特徴,
第101回日本循環器学会四国地方会, 2012年12月. T Hara, 山口浩司, 岩瀬俊, M Kadota, K Ogasawara, 坂東美佳, S Bando, T Matsuura, J Hotchi, N Tomita, 伊勢孝之, 仁木敏之, 上田由佳, 竹谷善雄, 山田博胤, 添木武, 若槻哲三, S Orino, 佐田政隆 :
Churg-Strauss症候群に合併した好酸球性心筋炎の一例,
第101回日本循環器学会四国地方会, 2012年12月. Koji Yamaguchi, Tetsuzo Wakatsuki, Toshiyuki Niki, Yoshio Taketani, H Oezuka, R Ota, Y Kawabata, T Hara, M Kadota, K Ogasawara, S Bando, T Matuura, J Hotchi, Takayuki Ise, Shusuke Yagi, Takashi Iwase, Hirotsugu Yamada, Takeshi Soeki and Masataka Sata :
Telmisartan reduces local inflammatory response and coronary plaque vulnerability assessed by integrated backscatter intravascular ultrasound in hypertensive patients.,
第20回日本血管生物医学会学術集会, Dec. 2012. M Kadota, Takayuki Ise, Takashi Iwase, Masashi Akaike, Koji Yamaguchi, Yoshio Taketani, Hirotsugu Yamada, Tetsuzo Wakatsuki, Takeshi Soeki and Masataka Sata :
Prediction of Responder and Influence for Cardio-Renal Interaction by Tolvaptan in Patients with Chronic Heart Failure.,
第16回日本心不全学会学術集会, Nov. 2012. Takayuki Ise, Shusuke Yagi, Masashi Akaike, Takashi Iwase, M Kadota, T Hara, Koji Yamaguchi, Yoshio Taketani, Tetsuzo Wakatsuki and Masataka Sata :
Acute Hemodynamic Effects of Adaptive Servo-Ventilation in Patients with Chronic Heart Failure.,
第16回日本心不全学会学術集会, Nov. 2012. 仁木敏之, 若槻哲三, 坂東美佳, 西尾進, 小笠原梢, 坂東左知子, 伊勢孝之, 發知淳子, 山口浩司, 竹谷善雄, 岩瀬俊, 冨田紀子, 山田博胤, 添木武, 佐田政隆 :
スタチンへのEPA製剤追加による動脈硬化病変の組織性状変化に関する検討,
第60回日本心臓病学会学術集会, 2012年9月. S Bando, 添木武, 伊勢孝之, 岩瀬俊, T Hara, M Kadota, 坂東美佳, K Ogasawara, J Hotchi, N Tomita, 仁木敏之, 山口浩司, 竹谷善雄, 山田博胤, 若槻哲三, 佐田政隆 :
心房周囲炎症と心囊液貯留により収縮性心膜炎の病態を呈した一例,
第60回日本心臓病学会学術集会, 2012年9月. 山口浩司, 若槻哲三, 仁木敏之, 竹谷善雄, S Bando, 伊勢孝之, 岩瀬俊, 山田博胤, 添木武, 佐田政隆 :
シロリムス溶出ステント留置後における局所血管反応の検討-局所バイオマーカーとperi-contrast stainingの観点から-,
第60回日本心臓病学会学術集会, 2012年9月. 伊勢孝之, 岩瀬俊, K Nanjo, 髙尾正一郎, R Ota, S Bando, 仁木敏之, 上田由佳, 山口浩司, 竹谷善雄, 山田博胤, 添木武, 若槻哲三, 赤池雅史, 原田雅史, 佐田政隆 :
心臓MRIを用いた左室肥大患者における右室壁厚の検討,
第60回日本心臓病学会学術集会, 2012年9月. 添木武, 山口浩司, 仁木敏之, K Ogasawara, 坂東美佳, S Bando, T Matsuura, N Tomita, 上田由佳, 伊勢孝之, 竹谷善雄, 岩瀬俊, 山田博胤, 若槻哲三, 島袋充生, 佐田政隆 :
血中micro RNAは冠動脈不安定プラークのバイオマーカーになりえるか?,
第60回日本心臓病学会学術集会, 2012年9月. S Bando, 添木武, T Matsuura, 坂東美佳, K Ogasawara, J Hotchi, N Tomita, 伊勢孝之, 仁木敏之, 山口浩司, 竹谷善雄, 岩瀬俊, 山田博胤, 若槻哲三, 島袋充生, 佐田政隆 :
NLRPインフラマソームと冠動脈硬化の関連について,
第60回日本心臓病学会学術集会, 2012年9月. 若槻哲三, 仁木敏之, 山口浩司, 伊勢孝之, 岩瀬俊, 竹谷善雄, 山田博胤, 添木武, 佐田政隆 :
OCTにてneovascularizationを認めた冠動脈プラークのIB-IVUSによる組織性状の評価,
第60回日本心臓病学会学術集会, 2012年9月. 仁木敏之, 若槻哲三, 坂東美佳, S Nishio, K Ogasawara, S Bando, 伊勢孝之, J Hotchi, 山口浩司, 竹谷善雄, 岩瀬俊, N Tomita, H Yamada, 添木武, 佐田政隆 :
スタチンへのEPA製剤追加による動脈硬化病変の組織性状変化に関する検討,
第60回日本心臓病学会学術集会, 2012年9月. 仁木敏之, 若槻哲三, K Ogasawara, 伊勢孝之, 山口浩司, 竹谷善雄, 岩瀬俊, 佐田政隆 :
Neovascularizationを認めた冠動脈プラークの組織性状の評価-OCTおよびIB-IVUS所見の比較検討-,
第19回日本心血管インターベンション治療学会中国・四国地方会, 2012年9月. Y Yokota, M Kadota, 伊勢孝之, 岩瀬俊, T Hara, R Ota, Y Kawabata, K Ogasawara, 坂東美佳, S Bando, T Matsuura, 仁木敏之, J Hotchi, N Tomita, 上田由佳, 山口浩司, 竹谷善雄, 山田博胤, 添木武, 若槻哲三, 佐田政隆, 赤池雅史, 江川麻理子, 三田村佳典 :
眼病変の経過中に心室中隔の肥厚および完全房室ブロックで発症した心サルコイドーシスの一例,
第245回徳島医学会学術集会(平成24年度夏期), 2012年7月. N Kawano, 仁木敏之, K Ogasawara, R Ota, M Kadota, Y Kawabata, T Hara, 伊勢孝之, T Matsuura, 上田由佳, 山口浩司, 竹谷善雄, 岩瀬俊, 山田博胤, 添木武, 若槻哲三, 佐田政隆, T Yamamoto, K Kawano, 角谷明佳, K Seto, 金山博臣 :
シスプラチン，エトポシド，ブレオマイシンの三剤化学療法併用中に急性心筋梗塞を発症した二例,
第245回徳島医学会学術集会(平成24年度夏期), 2012年7月. K Matsumoto, 仁木敏之, K Ogasawara, R Ota, M Kadota, Y Kawabata, T Hara, 伊勢孝之, T Matsuura, 上田由佳, 山口浩司, 竹谷善雄, 岩瀬俊, 山田博胤, 添木武, 若槻哲三, 佐田政隆, Y Sawa :
プロテインC活性低下を背景とし，オートマチック車への変更を契機に肺血栓塞栓症を発症したタクシー運転手の一例,
第245回徳島医学会学術集会(平成24年度夏期), 2012年7月. N Kobayashi, T Hara, 山口浩司, M Kadota, R Ota, Y Kawabata, K Ogasawara, 坂東美佳, S Bando, T Matsuura, J Hotchi, N Tomita, 伊勢孝之, 仁木敏之, 上田由佳, 竹谷善雄, 岩瀬俊, 山田博胤, 添木武, 若槻哲三, 佐田政隆, M Bando :
著名な自立神経障害を背景とした治療抵抗性夜間高血圧症の一例,
第245回徳島医学会学術集会(平成24年度夏期), 2012年7月. 上田由佳, 岩瀬俊, 伊勢孝之, K Maeda, K Nishikawa, 坂東美佳, K Ogasawara, S Bando, 仁木敏之, J Hotchi, 山口浩司, N Tomita, 竹谷善雄, 山田博胤, 添木武, 若槻哲三, 赤池雅史, 加藤真介, 安井夏生, 佐田政隆 :
喫煙継続者における心臓リハビリテーションの効果の検討,
第18回心臓リハビリテーション学会, 2012年7月. K Maeda, 上田由佳, 伊勢孝之, 岩瀬俊, K Nishikawa, 坂東美佳, K Ogasawara, S Bando, 仁木敏之, J Hotchi, 山口浩司, N Tomita, 竹谷善雄, 山田博胤, 添木武, 若槻哲三, 赤池雅史, 加藤真介, 安井夏生, 佐田政隆 :
患者の気持ちを汲んだ患者教育の実際,
第18回心臓リハビリテーション学会, 2012年7月. A Takashima, 伊勢孝之, 上田由佳, K Maeda, K Nishikawa, K Ogasawara, 坂東美佳, N Tomita, 仁木敏之, J Hotchi, 山口浩司, 竹谷善雄, 岩瀬俊, 山田博胤, 添木武, 若槻哲三, 加藤真介, 赤池雅史, 安井夏生, 佐田政隆 :
心臓リハビリテーションは酸化LDLを低下させる,
第18回心臓リハビリテーション学会, 2012年7月. S Bando, 添木武, 伊勢孝之, 岩瀬俊, 坂東美佳, K Ogasawara, J Hotchi, N Tomita, 仁木敏之, 山口浩司, 竹谷善雄, 山田博胤, 若槻哲三, 菅野幹雄, 神原保, 北川哲也, 佐田政隆 :
心房周囲炎症と心囊液貯留により収縮性心膜炎の病態を呈した一例,
第100回日本循環器学会中国・四国合同地方会, 2012年6月. A Tachibana, 伊勢孝之, 添木武, 岩瀬俊, R Ota, M Kadota, T Hara, 坂東美佳, K Ogasawara, S Bando, 仁木敏之, J Hotchi, N Tomita, 上田由佳, 山口浩司, 竹谷善雄, 山田博胤, 若槻哲三, 赤池雅史, 佐田政隆 :
CRT-Dが著効した重症拡張型心筋症の2症例,
第100回日本循環器学会中国・四国合同地方会, 2012年6月. S Nagasaka, 伊勢孝之, 岩瀬俊, R Ota, M Kadota, T Hara, 坂東美佳, K Ogasawara, S Bando, 仁木敏之, J Hotchi, N Tomita, 上田由佳, 山口浩司, 竹谷善雄, 山田博胤, 添木武, 若槻哲三, 赤池雅史, 佐田政隆 :
マルチモダリティを用いて鑑別し得た冠動脈病変合併たこつぼ型心筋症の1症例,
第100回日本循環器学会中国・四国合同地方会, 2012年6月. 伊勢孝之, K Nanjo, 岩瀬俊, 髙尾正一郎, R Ota, M Kadota, T Hara, 坂東美佳, K Ogasawara, S Bando, 仁木敏之, 上田由佳, 山口浩司, 竹谷善雄, 山田博胤, 添木武, 若槻哲三, 赤池雅史, 原田雅史, 佐田政隆 :
左室肥大患者における右室壁厚の検討,
第100回日本循環器学会中国・四国合同地方会, 2012年6月. J Hotchi, S Taoka, 坂東美佳, K Ogasawara, A Takashima, H Yamasaki, S Bando, 伊勢孝之, 仁木敏之, 山口浩司, 上田由佳, N Tomita, 竹谷善雄, 岩瀬俊, 山田博胤, 添木武, 若槻哲三, Y Saijo, 佐田政隆 :
緊密な病診連携と詳細な副腎静脈サンプリングが迅速な根治術につながった原発性アルドステロン症の一例,
第100回日本循環器学会中国・四国合同地方会, 2012年6月. 伊勢孝之, 岩瀬俊, R Ota, M Kadota, T Hara, A Takashima, H Yamasaki, 坂東美佳, K Ogasawara, S Bando, 仁木敏之, J Hotchi, N Tomita, 上田由佳, 山口浩司, 竹谷善雄, 山田博胤, 添木武, 若槻哲三, 赤池雅史, 佐田政隆 :
Adaptive Servo-Ventilationが心不全治療に有効であった心アミロイドーシスの2症例,
第100回日本循環器学会中国・四国合同地方会, 2012年6月. K Maeda, 上田由佳, 伊勢孝之, 岩瀬俊, K Nishikawa, 坂東美佳, K Ogasawara, S Bando, 仁木敏之, J Hotchi, 山口浩司, N Tomita, 竹谷善雄, 山田博胤, 添木武, 若槻哲三, 赤池雅史, 加藤真介, 安井夏生, 佐田政隆 :
チーム医療で取り組む重症心不全に対する心臓リハビリテーション,
第100回日本循環器学会中国・四国合同地方会, 2012年6月. S Taoka, 伊勢孝之, 岩瀬俊, R Ota, M Kadota, T Hara, K Ogasawara, 坂東美佳, S Bando, 仁木敏之, J Hotchi, N Tomita, 上田由佳, 山口浩司, 竹谷善雄, 山田博胤, 添木武, 若槻哲三, 赤池雅史, 佐田政隆 :
テニスラケットによる打撲が誘引で深部静脈血栓・急性肺塞栓症を来した1症例,
第100回日本循環器学会中国・四国合同地方会, 2012年6月. K Ogasawara, 仁木敏之, 坂東美佳, S Bando, 伊勢孝之, J Hotchi, 上田由佳, 山口浩司, 岩瀬俊, 竹谷善雄, N Tomita, 山田博胤, 添木武, 若槻哲三, 島袋充生, 佐田政隆 :
永久型下大静脈フィルター血栓閉塞に対し抗凝固療法を中心とした保存的加療が有効であった2症例,
第100回日本循環器学会中国・四国合同地方会, 2012年6月. 坂東美佳, 山田博胤, K Ogasawara, 仁木敏之, N Tomita, J Hotchi, R Tamai, Y Hirata, D Hirota, S Nishio, S Bando, 伊勢孝之, 上田由佳, 山口浩司, 岩瀬俊, 竹谷善雄, 添木武, 若槻哲三, 佐田政隆, H Kawano, 西岡安彦 :
肺動脈血栓に対してフォンダパリヌクスが著効した静脈血栓塞栓症の一例,
第100回日本循環器学会中国・四国合同地方会, 2012年6月. R Tamai, 坂東美佳, 山田博胤, S Nishio, N Tomita, J Hotchi, S Hayashi, M Nakagawa, Y Hirata, D Hirota, K Ogasawara, H Yamasaki, S Bando, 伊勢孝之, 仁木敏之, 山口浩司, 岩瀬俊, 竹谷善雄, 添木武, 若槻哲三, 佐田政隆 :
超音波後方散乱信号を用いたカラーマッピングシステムの脂質低下療法における臨床応用:case report,
第100回日本循環器学会中国・四国合同地方会, 2012年6月. Y Oguro, 仁木敏之, K Ogasawara, 坂東美佳, S Bando, 伊勢孝之, J Hotchi, 上田由佳, 山口浩司, 竹谷善雄, 岩瀬俊, N Tomita, 山田博胤, 添木武, 若槻哲三, 佐田政隆 :
マニュアル車からオートマチック車に変更後に左下肢深部静脈血栓症を生じたタクシー運転手の一例,
第100回日本循環器学会中国・四国合同地方会, 2012年6月. 森住俊, J Hotchi, 山田博胤, 坂東美佳, H Yamasaki, K Ogasawara, K Takashima, S Bando, 伊勢孝之, 仁木敏之, 山口浩司, N Tomita, 上田由佳, 岩瀬俊, 竹谷善雄, 添木武, 若槻哲三, 佐田政隆 :
完全房室ブロックを合併して恒久的ペースメーカー植込みを必要としたたこつぼ型心筋症の一症例,
第100回日本循環器学会中国・四国合同地方会, 2012年6月. N Kawano, 仁木敏之, K Ogasawara, 坂東美佳, S Bando, 伊勢孝之, J Hotchi, 上田由佳, 山口浩司, 竹谷善雄, 岩瀬俊, N Tomita, 山田博胤, 添木武, 若槻哲三, T Yamamoto, K Kawano, 角谷明佳, 佐田政隆 :
シスプラチン，エトポシド，ブレオマイシンの三剤化学療法併用中に急性心筋梗塞を発症した二例,
第100回日本循環器学会中国・四国合同地方会, 2012年6月. 山口浩司, 若槻哲三, 添木武, 仁木敏之, 竹谷善雄, H Oezuka, K Ogasawara, 坂東美佳, S Bando, J Hotchi, 上田由佳, N Sakamoto, 伊勢孝之, 岩瀬俊, 山田博胤, 佐田政隆 :
テルミサルタンの冠動脈プラークに対する抗動脈硬化作用の検討,
第100回日本循環器学会中国・四国合同地方会, 2012年6月. S Hayashi, M Sato, 山田博胤, N Tomita, J Hotchi, 坂東美佳, S Nishio, R Tamai, M Nakagawa, D Hirota, Y Hirata, 伊勢孝之, 仁木敏之, 山口浩司, 竹谷善雄, 岩瀬俊, 添木武, 若槻哲三, 佐田政隆 :
僧帽弁輪運動速波形指標およびAugmentation Indenxの性差と相互連関についての検討,
第23回日本心エコー図学会学術集会, 2012年4月. Tomita Noriko, 山田博胤, 楠瀬賢也, Nishio Susumu, Hotchi Junko, Hayashi Shuji, 坂東美佳, Bando Sachiko, 伊勢孝之, 仁木敏之, 山口浩司, 岩瀬俊, 竹谷善雄, 添木武, 若槻哲三, 佐田政隆 :
Clinical Efficacy of Beat-to-beat Variability of Diastolic Filling in Atrial Fibrillation.,
第76回日本循環器学会学術集会, 2012年3月. Bando Sachiko, Takeshi Soeki, Ogasawara Kozue, Takashima Akira, Mika Bando, Yamazaki Hiromu, Hotchi Junko, Tomita Noriko, Takayuki Ise, Toshiyuki Niki, Koji Yamaguchi, Yoshio Taketani, Takashi Iwase, Hirotsugu Yamada, Tetsuzo Wakatsuki, Michio Shimabukuro and Masataka Sata :
Relationship between NLRP3 Inflammasome and Coronary Atherosclerosis.,
第76回日本循環器学会学術集会, Mar. 2012. Hotchi Junko, Hirotsugu Yamada, Kenya Kusunose, Nishio Susumu, Mika Bando, Tomita Noriko, Hayashi Shuji, Bando Sachiko, Toshiyuki Niki, Takayuki Ise, Koji Yamaguchi, Takashi Iwase, Yoshio Taketani, Takeshi Soeki, Tetsuzo Wakatsuki and Masataka Sata :
Effect of Irbesartan on Left Ventricular Myocardial Function in Patients with Hypertension: Assessment by Two-dimensional Speckle Tracking Echocardiography.,
第76回日本循環器学会学術集会, Mar. 2012. Koji Yamaguchi, Tetsuzo Wakatsuki, Toshiyuki Niki, Yoshio Taketani, Bando Sachiko, Hotchi Junko, Tomita Noriko, Takayuki Ise, Takashi Iwase, Hirotsugu Yamada, Takeshi Soeki and Masataka Sata :
Angiographic Peri-stent Contrast Staining Leading to Local Persistent Hypercoagulability up to Five Years after Sirolimus-eluting Stent Implantation:Comparison with Bare-Metal Stent.,
第76回日本循環器学会学術集会, Mar. 2012. Kimura Sahika, 上田由佳, 伊勢孝之, 岩瀬俊, Takashima Akira, Yamazaki Hiromu, Ogasawara Kozue, Bando Sachiko, Hayashi Shuji, Takeuchi Hidekazu, 仁木敏之, 楠瀬賢也, 山口浩司, Tomita Noriko, 竹谷善雄, 山田博胤, 添木武, 若槻哲三, 赤池雅史, 佐田政隆 :
Cardiac Rehabilitation decreases Urinary Albumin Excretion in Patients with Cardiovascular Disease.,
第76回日本循環器学会学術集会, 2012年3月. Takashima Akira, Takayuki Ise, Takashi Iwase, Yuka Ueda, Masashi Akaike, Yamazaki Hiromu, Mika Bando, Ogasawara Kozue, Bando Sachiko, Tomita Noriko, Takeuchi Hidekazu, Toshiyuki Niki, Hotchi Junko, Koji Yamaguchi, Yoshio Taketani, Hirotsugu Yamada, Takeshi Soeki, Tetsuzo Wakatsuki and Masataka Sata :
Effect of Cardiac Rehabilitation on Level of Oxidized LDL.,
第76回日本循環器学会学術集会, Mar. 2012. 添木武, 仁木敏之, 山口浩司, 坂東左知子, 上田由佳, 冨田紀子, 伊勢孝之, 楠瀬賢也, 竹谷善雄, 岩瀬俊, 山田博胤, 若槻哲三, 赤池雅史, 島袋充生, 佐田政隆 :
Inflammatory Biomarkers as Predictors of Vulnerable Coronary Plaques.,
第76回日本循環器学会学術集会，Symposium 3, 2012年3月. 山田博胤, 西尾進, 坂東美佳, 發知淳子, 林修司, 冨田紀子, 伊勢孝之, 仁木敏之, 山口浩司, 竹谷善雄, 岩瀬俊, 添木武, 若槻哲三, 佐田政隆 :
Carotid Ultrasound Imaging to Evaluate Atherosclerotic Diseases.,
第76回日本循環器学会学術集会，KSC-JCS Joint Symposium-2, 2012年3月. 立花綾香, 上田由佳, 伊勢孝之, 高島啓, 山崎宙, 小笠原梢, 坂東左知子, 仁木敏之, 發知淳子, 冨田紀子, 山口浩司, 竹谷善雄, 岩瀬俊, 山田博胤, 添木武, 若槻哲三, 佐田政隆, 赤池雅史, 廣野明 :
CRT-Dが著効した重症慢性心不全の1例,
第244回徳島医学会学術集会 (平成23年度冬期), 2012年2月. 田岡志保, 上田由佳, 伊勢孝之, 高島啓, 山崎宙, 小笠原梢, 坂東左知子, 仁木敏之, 發知淳子, 冨田紀子, 山口浩司, 竹谷善雄, 岩瀬俊, 山田博胤, 添木武, 若槻哲三, 佐田政隆, 赤池雅史, 井上洋行 :
テニスラケットによる外傷が誘因で深部静脈血栓・急性肺塞栓症を来した一症例,
第244回徳島医学会学術集会 (平成23年度冬期), 2012年2月. 森住俊, 發知淳子, 山田博胤, 山崎宙, 小笠原梢, 高島啓, 坂東美佳, 坂東左知子, 竹内秀和, 伊勢孝之, 仁木敏之, 山口浩司, 冨田紀子, 上田由佳, 岩瀬俊, 竹谷善雄, 添木武, 若槻哲三, 佐田政隆, 久保克之, 佐々木克哉, 富田芳雄 :
たこつぼ型心筋症に完全房室ブロックを合併した一症例,
第244回徳島医学会学術集会 (平成23年度冬期), 2012年2月. 坂東美佳, 山田博胤, 冨田紀子, 發知淳子, 小笠原梢, 高島啓, 山崎宙, 坂東左知子, 伊勢孝之, 仁木敏之, 上田由佳, 山口浩司, 岩瀬俊, 竹谷善雄, 添木武, 若槻哲三, 赤池雅史, 佐田政隆, 西尾進, 林修司, 中川摩耶, 玉井利奈, 平田有紀奈, 弘田大智 :
脂質低下療法による頸動脈プラーク安定化の評価:超音波integrated backscatterを用いたカラーマッピングシステムの臨床応用,
第244回徳島医学会学術集会 (平成23年度冬期), 2012年2月. 山口浩司, 若槻哲三, 添木武, 仁木敏之, 竹谷善雄, 小笠原梢, 坂東美佳, 坂東左知子, 發知淳子, 上田由佳, 冨田紀子, 竹内秀和, 伊勢孝之, 岩瀬俊, 山田博胤, 佐田政隆, 麻植塚浩康 :
テルミサルタンの冠動脈プラークに対する抗動脈硬化作用の検討,
第244回徳島医学会学術集会 (平成23年度冬期), 2012年2月. 仁木敏之, 小笠原梢, 坂東美佳, 坂東左知子, 竹内秀和, 伊勢孝之, 發知淳子, 上田由佳, 山口浩司, 岩瀬俊, 竹谷善雄, 冨田紀子, 山田博胤, 添木武, 若槻哲三, 佐田政隆, 中瀧恵実子, 西村匡司, 上山祐二 :
低体温療法が著効し社会復帰をなし得たBrugada症候群の一例,
第244回徳島医学会学術集会 (平成23年度冬期), 2012年2月. 仁木敏之, 若槻哲三, 山口浩司, 竹谷善雄, 岩瀬俊, 麻植塚浩康, 西尾進, 小笠原梢, 坂東美佳, 坂東左知子, 伊勢孝之, 冨田紀子, 山田博胤, 添木武, 佐田政隆 :
冠動脈プラークに対するスタチンへのEPA製剤add on 効果の検討-IB-IVUSおよびIB-頸動脈エコーの観点から-,
第22回日本心血管画像動態学会, 2012年1月. 前田香代子, 上田由佳, 伊勢孝之, 岩瀬俊, 西川幸治, 高島啓, 小笠原梢, 山崎宙, 坂東左知子, 仁木敏之, 發知淳子, 山口浩司, 冨田紀子, 竹谷善雄, 山田博胤, 添木武, 若槻哲三, 赤池雅史, 髙田信二郎, 安井夏生, 佐田政隆 :
大学病院での心臓リハビリテーション立ち上げの問題点,
第99回日本循環器学会四国地方会, 2011年12月. 坂東美佳, 林修司, 山田博胤, 冨田紀子, 發知淳子, 西尾進, 玉井利奈, 平田有紀奈, 弘田大智, 小笠原梢, 高島啓, 山崎宙, 坂東左知子, 伊勢孝之, 仁木敏之, 山口浩司, 岩瀬俊, 竹谷善雄, 添木武, 若槻哲三, 佐田政隆 :
平滑筋肉腫の心筋内転移の診断，経過観察に経胸壁心エコー法が有用であった一例,
第99回日本循環器学会四国地方会, 2011年12月. 高島啓, 山口浩司, 原知也, 山崎宙, 小笠原梢, 坂東左知子, 發知淳子, 冨田紀子, 竹内秀和, 仁木敏之, 伊勢孝之, 上田由佳, 竹谷善雄, 岩瀬俊, 山田博胤, 添木武, 若槻哲三, 花岡潤, 島田光生, 佐田政隆 :
真性多血症患者に発症した心原生脾梗塞の1例,
第99回日本循環器学会四国地方会, 2011年12月. 田根なつ紀, 山口浩司, 竹谷善雄, 高島啓, 山崎宙, 小笠原梢, 坂東左知子, 仁木敏之, 伊勢孝之, 發知淳子, 岩瀬俊, 冨田紀子, 山田博胤, 添木武, 若槻哲三, 佐田政隆 :
重症下肢虚血病変に対して経皮的下肢動脈形成術が奏功し，予定されていた下肢切断手術を回避できた一症例,
第99回日本循環器学会四国地方会, 2011年12月. 高橋直希, 仁木敏之, 高島啓, 山崎宙, 小笠原梢, 坂東左知子, 伊勢孝之, 發知淳子, 山口浩司, 岩瀬俊, 竹谷善雄, 冨田紀子, 山田博胤, 添木武, 若槻哲三, 佐田政隆, 中瀧恵実子, 西村匡司, 上山祐二 :
低体温療法が著効し社会復帰をなし得たBrugada症候群の一例,
第99回日本循環器学会四国地方会, 2011年12月. 藤岡啓介, 山崎宙, 伊勢孝之, 楠瀬賢也, 木村白陽花, 高島啓, 小笠原梢, 坂東左知子, 發知淳子, 冨田紀子, 竹内秀和, 上田由佳, 仁木敏之, 山口浩司, 竹谷善雄, 岩瀬俊, 山田博胤, 添木武, 若槻哲三, 佐田政隆 :
ULPの発生から拡大，消失までを経時的に観察し得たacute aortic syndromeの一例,
第99回日本循環器学会四国地方会, 2011年12月. 山崎宙, 楠瀬賢也, 伊勢孝之, 竹谷善雄, 若槻哲三, 手塚敏史, 柿内聡司, 西岡安彦, 坂東良美, 佐田政隆 :
稀な画像所見を呈する肺アスペルギルス症により治療抵抗性心不全を認めた1症例,
第105回日本内科学会四国地方会, 2011年11月. 坂東左知子, 添木武, 伊勢孝之, 竹谷善雄, 岩瀬俊, 山田博胤, 若槻哲三, 木村建彦, 西内健, 佐田政隆 :
CRT-Dによって僧帽弁閉鎖不全症が劇的に改善した突発性拡張型心筋症の1例,
第105回日本内科学会四国地方会, 2011年11月. 岩瀬俊, 髙尾正一郎, 赤池雅史, 能勢隼人, 伊勢孝之, 小笠原梢, 山崎宙, 髙島啓, 坂東左知子, 仁木敏之, 楠瀬賢也, 發知淳子, 冨田紀子, 上田由佳, 山口浩司, 山田博胤, 添木武, 若槻哲三, 西岡安彦, 原田雅史, 佐田政隆 :
心臓MRIによるサルコイドーシス心病変検出の有用性,
第31回日本サルコイドーシス/肉芽腫性疾患学会総会, 2011年10月. Takayuki Ise, Takashi Iwase, Kumiko Kagawa, Toshiyuki Niki, Kenya Kusunose, 冨田紀子, Yuka Ueda, Koji Yamaguchi, Yoshio Taketani, Hirotsugu Yamada, Takeshi Soeki, Tetsuzo Wakatsuki, Masahiro Abe, Masashi Akaike and Masataka Sata :
Successful Autologous Peripheral Blood Stem Cell Transplantation for Primary Cardiac Amyloidosis Patients with Heart Failure : three cases report.,
第15回日本心不全学会学術集会, Oct. 2011. 岩瀬俊, 髙尾正一郎, 赤池雅史, 能勢隼人, 久岡白陽花, 伊勢孝之, 仁木敏之, 楠瀬賢也, 山口浩司, 竹谷善雄, 山田博胤, 添木武, 若槻哲三, 西岡安彦, 原田雅史, 佐田政隆 :
サルコイドーシス心病変検出における心臓MRI検査の有用性,
第59回日本心臓病学会学術集会, 2011年9月. 吉田守美子, 粟飯原賢一, 伊勢孝之, 上田由佳, 池田康将, 岩瀬俊, 赤池雅史, 佐田政隆, 松本俊夫 :
Eicosapentaenoic acid protects against angiotensin II-induced cardiovascular remodeling via attenuation of oxidative stress.,
第75回日本循環器学会総会・学術集会パシフィコ横浜, 2011年8月. 原知也, 岩瀬俊, 高島啓, 山崎宙, 小笠原梢, 坂東左知子, 伊勢孝之, 仁木敏之, 楠瀬賢也, 上田由佳, 冨田紀子, 山口浩司, 竹谷善雄, 山田博胤, 添木武, 若槻哲三, 佐田政隆 :
心サルコイドーシス診断の手引きにおける各種診断モダリティーの検討,
第243回徳島医学会学術集会, 2011年7月. 添木武, 仁木敏之, 山口浩司, S. Bando, 上田由佳, N. Tomita, 伊勢孝之, 楠瀬賢也, 竹谷善雄, 岩瀬俊, 山田博胤, 若槻哲三, 赤池雅史, 島袋充生, 佐田政隆 :
Inflammatory Biomarkers as Predictors of Vulnerable Coronary Plaques.,
第76回日本循環器学会学術集会，Symposium 3, 2011年3月. 吉田守美子, 粟飯原賢一, 伊勢孝之, 上田由佳, 池田康将, 岩瀬俊, 赤池雅史, 佐田政隆, 松本俊夫 :
A role of androgen receptor in ischemia-induced tissue damage and angiogenesis in male,
第42回日本動脈硬化学会総会・学術集会長良川国際会議場, 2010年7月. 吉田守美子, 粟飯原賢一, 伊勢孝之, 上田由佳, 池田康将, 岩瀬俊, 赤池雅史, 佐田政隆, 松本俊夫 :
Accelerated cellular apoptosis and impaired angiogenesis after hindlimb ischemia in male mice lacking androgen receptor,
第74回日本循環器学会総会・学術集会国立京都国際会館, 2010年3月. 吉田守美子, 粟飯原賢一, 伊勢孝之, 住友由佳, 松本俊夫, 八木秀介, 岩瀬俊, 赤池雅史, 山田博胤, 佐田政隆, 西尾進 :
副腎アンドロゲンDHEASの抗動脈硬化作用における性差の検討,
第32回日本高血圧学会学術集会, 2009年10月. 吉田守美子, 粟飯原賢一, 西尾進, 倉橋清衛, 遠藤逸朗, 藤中雄一, 伊勢孝之, 住友由佳, 八木秀介, 岩瀬俊, 山田博胤, 赤池雅史, 佐田政隆, 松本俊夫 :
副腎アンドロゲンDHEASは血管内皮機能非依存的に頸動脈硬化を抑制する,
第82回日本内分泌学会学術総会, Vol.85, No.1, 366, 2009年4月.

(キーワード): *頸動脈疾患 *血管内皮 *動脈硬化症 *Dehydroepiandrosterone Sulfate(薬理学) ヒト男女

粟飯原賢一, 吉田守美子, 伊勢孝之, 住友由佳, 八木秀介, 岩瀬俊, 倉橋清衛, 遠藤逸朗, 藤中雄一, 赤池雅史, 佐田政隆, 松本俊夫 :
Increased serum triglyceride but not LDL cholesterol is associated with left ventricular diastolic dysfunction.,
第73回日本循環器学会総会・学術集会, 2009年3月. 吉田守美子, 粟飯原賢一, 伊勢孝之, 住友由佳, 八木秀介, 岩瀬俊, 倉橋清衛, 遠藤逸朗, 藤中雄一, 赤池雅史, 佐田政隆, 松本俊夫 :
Dehydroepiandrosterone sulfate is an antivascular remodeling factor,
第73回日本循環器学会総会・学術集会, 2009年3月. 住友由佳, 粟飯原賢一, 伊勢孝之, 吉田守美子, 八木秀介, 岩瀬俊, 赤池雅史, 佐田政隆, 松本俊夫 :
Heparin Cofactor II-deficient Mice Exert Exacerbation of Angiotensin II-induced Cardiac Remodeling through Enhancement of NADPH oxidase - TGF- 1 Pathway,
第73回日本循環器学会総会・学術集会, 2009年3月. 粟飯原賢一, 吉田守美子, 伊勢孝之, 住友由佳, 倉橋清衛, 遠藤逸朗, 藤中雄一, 松本俊夫, 八木秀介, 岩瀬俊, 赤池雅史, 佐田政隆 :
左室拡張能に対する脂質代謝異常の意義,
第31回日本高血圧学会総会, 2008年10月. 吉田守美子, 粟飯原賢一, 伊勢孝之, 住友由佳, 松本俊夫, 八木秀介, 岩瀬俊, 赤池雅史, 佐田政隆 :
副腎アンドロゲンDHEASは頚動脈血流の制御因子である,
第31回日本高血圧学会学術集会, 2008年10月. 住友由佳, 粟飯原賢一, 伊勢孝之, 吉田守美子, 松本俊夫, 八木秀介, 岩瀬俊, 添木武, 赤池雅史, 佐田政隆 :
ヘパリンコファクターⅡは抗酸化ストレス作用を介してアンジオテンシンIIによる心房および心室のリモデリングを抑制する,
第31回日本高血圧学会総会, 2008年10月. 吉田守美子, 粟飯原賢一, 伊勢孝之, 住友由佳, 松本俊夫, 八木秀介, 岩瀬俊, 赤池雅史, 佐田政隆 :
副腎アンドロゲンDHEASの血管への作用(頚動脈エコーを用いた臨床的検討),
第13回武田高血圧シンポジウム, 2008年10月. 粟飯原賢一, 吉田守美子, 伊勢孝之, 住友由佳, 八木秀介, 岩瀬俊, 遠藤逸朗, 藤中雄一, 赤池雅史, 松本俊夫 :
脂質代謝異常による左室拡張障害の臨床的検討,
第40回日本動脈硬化学会総会, 249, 2008年7月.

(キーワード): 脂質異常症(合併症) / 左心室機能障害(病因) / ヒト (Homo sapiens) / 男性 (male) / 女性 (female)

吉田守美子, 粟飯原賢一, 伊勢孝之, 住友由佳, 八木秀介, 岩瀬俊, 遠藤逸朗, 藤中雄一, 赤池雅史, 松本俊夫 :
副腎アンドロゲンの頸動脈硬化抑制作用に関する検討,
第40回日本動脈硬化学会総会, 253, 2008年7月.

(キーワード): Androgens(治療的利用) / 頸動脈疾患(予防) / 頸動脈疾患(予防) / 動脈硬化症(予防) / 副腎 / ヒト (Homo sapiens) / 男性 (male) / 女性 (female)

八木秀介, 粟飯原賢一, 伊勢孝之, 吉田守美子, 住友由佳, 池田康将, 岩瀬俊, 添木武, 赤池雅史, 松本俊夫 :
ピタバスタチンはRac-1を介した酸化ストレス制御によりeNOS非依存的にアンジオテンシンIIによる心房リモデリングを抑制する,
第40回日本動脈硬化学会総会, 203, 2008年7月.

(キーワード): *Angiotensin II 抗酸化剤(治療的利用) 心房 *動脈硬化症(薬物療法) 酸化ストレス rac GTP-Binding Proteins 心室リモデリング *Pitavastatin(治療的利用) マウス動物

吉田守美子, 粟飯原賢一, 木内美瑞穂, 遠藤逸朗, 藤中雄一, 伊勢孝之, 住友由佳, 八木秀介, 岩瀬俊, 赤池雅史, 松本俊夫 :
頸動脈血行動態における副腎アンドロゲンの臨床的意義,
第81回日本内分泌学会学術総会, Vol.84, No.1, 202, 2008年5月.

(キーワード): *Androgens(血液) *頸動脈 *副腎血行力学ヒト成人(19~44) 男女

粟飯原賢一, 吉田守美子, 伊勢孝之, 住友由佳, 八木秀介, 岩瀬俊, 木内美瑞穂, 遠藤逸朗, 藤中雄一, 赤池雅史, 松本俊夫 :
左室拡張能における脂質代謝異常の影響に関する検討,
第81回日本内分泌学会学術総会, Vol.84, No.1, 222, 2008年5月.

(キーワード): *脂質異常症 *左心室機能ヒト成人(19~44) 男女

近藤剛史, 小島直, 伊勢孝之, 木内美瑞穂, 吉田守美子, 栗若里佳, 遠藤逸朗, 粟飯原賢一, 藤中雄一, 松本俊夫 :
進行性の頭蓋骨陥凹と骨粗鬆症を来たした一例,
第81回日本内分泌学会学術総会, Vol.83, No.4, 834, 2008年5月.

(キーワード): *骨粗鬆症(合併症) *骨発育異常(合併症) 鑑別診断頭蓋骨ヒト成人(19~44) 女

粟飯原賢一, 伊勢孝之, 吉田守美子, 住友由佳, 八木秀介, 岩瀬俊, 赤池雅史, 松本俊夫 :
1α 25 dihydroxyvitamin D3 is a protective factor against vascular remodeling and glucose tolerance in elderly individuals,
第72回日本循環器学会学術集会, 2008年3月. 住友由佳, 粟飯原賢一, 伊勢孝之, 吉田守美子, 八木秀介, 岩瀬俊, 石川カズ江, 赤池雅史, 松本俊夫 :
Angiotensin II-induced cardiac remodeling is exacerbated with increased oxidative stress in heparin cofactor II-deficient mice.,
第72回日本循環器学会総会・学術集会, 2008年3月. 赤池雅史, 八木秀介, 粟飯原賢一, 池田康将, 石川カズ江, 伊勢孝之, 吉田守美子, 住友由佳, 岩瀬俊, Abe Jun-ichi, 松本俊夫 :
HMG-CoA Reductase Inhibitor Pitavastatin Increases the Expression of Endothelial NOS through Activation of ERK5-KLF2 Pathway in Vascular Endothelial Cells,
第72回日本循環器学会学術集会, 2008年3月. 近藤剛史, 粟飯原賢一, 伊勢孝之, 木内美瑞穂, 吉田守美子, 遠藤逸朗, 藤中雄一, 松本俊夫 :
心腎障害の改善にACE阻害薬とARBの併用が有効であった高レニン性高血圧症の1例,
第97回日本内科学会四国地方会, 2007年12月. 住友由佳, 粟飯原賢一, 伊勢孝之, 八木秀介, 岩瀬俊, 赤池雅史, 松本俊夫 :
レニン・アンジオテンシン活性下におけるヘパリンコファクターIIの心筋リモデリングへの影響,
第30回日本高血圧学会総会, 170, 2007年10月.

(キーワード): Angiotensins *Heparin Cofactor II Renin *心室リモデリングマウス動物

八木秀介, 粟飯原賢一, 池田康将, 伊勢孝之, 住友由佳, 岩瀬俊, 赤池雅史, 松本俊夫 :
Pitavastatinはangiotensin IIによる心腎障害をeNOS非依存性にrac1抑制による酸化ストレス抑制を介して改善する,
第30回日本高血圧学会総会, 205, 2007年10月.

(キーワード): Angiotensin II *心臓疾患(実験的) *腎臓疾患(実験的) *酸化ストレスノックアウトマウス rac GTP-Binding Proteins *Pitavastatin(薬理学) マウス動物

粟飯原賢一, 池田康将, 八木秀介, 伊勢孝之, 住友由佳, 岩瀬俊, 赤池雅史, 松本俊夫 :
血管リモデリング制御因子としての活性化ビタミンD,
第30回日本高血圧学会総会, 260, 2007年10月.

(キーワード): *Vitamin D(治療的利用) *動脈硬化症(薬物療法,診断) *血管リモデリングヒト男女

近藤剛史, 小島直, 伊勢孝之, 木内美瑞穂, 吉田守美子, 栗若里佳, 遠藤逸朗, 粟飯原賢一, 藤中雄一, 松本俊夫 :
進行性の頭蓋骨陥凹と骨粗鬆症を来たした一例,
日本内分泌学会第7回四国支部学術集会, Vol.83, No.4, 834, 2007年9月.

(キーワード): *骨粗鬆症(合併症) *骨発育異常(合併症) 鑑別診断頭蓋骨ヒト成人(19~44) 女

研究会・報告書: 東村優歩, 鈴木佳子, 大石琴乃, 石井亜由美, 西川幸治, 山田苑子, 伊勢孝之, 八木秀介, 松村晃子, 佐田政隆, 濵田康弘 :
心臓リハビリテーションと連携し，継続した栄養介入を行うことで減量が認められた一例,
日本心臓リハビリテーション学会第3回四国支部地方会, 2019年4月. 村上貴寛, 八木秀介, 原知也, 伊勢孝之, 楠瀬賢也, 松浦朋美, 飛梅威, 山口浩司, 山田博胤, 添木武, 若槻哲三, 島袋充生, 赤池雅史, 春藤譲治, 佐田政隆 :
原発性アルドステロン症の診断に有用な臨床所見の検討,
第253回徳島医学会学術集会(平成28年度夏期), 2016年7月. 山上圭, 西條良仁, 楠瀬賢也, 山田博胤, 瀬野弘光, 原知也, 上野理絵, 門田宗之, 齋藤友子, 山﨑宙, 坂東左知子, 伊藤浩敬, 轟貴史, 松浦朋美, 伊勢孝之, 飛梅威, 山口浩司, 八木秀介, 添木武, 若槻哲三, 佐田政隆 :
生体腎移植後における腎静脈-外腸骨静脈間の血流動態変化が一因と考えられた深部静脈血栓症の一例,
第253回徳島医学会学術集会(平成28年度夏期), 2016年7月. 山下雄也, 坂東美佳, 伊勢孝之, 楠瀬賢也, 山田博胤, 原知也, 高島啓, 山﨑宙, 斎藤友子, 坂東左知子, 飛梅威, 山口浩司, 八木秀介, 添木武, 若槻哲三, 木下肇, 藤本鋭貴, 北川哲也, 井上洋行, 佐田政隆 :
収縮期雑音を契機に発見された成人単純型大動脈狭窄症の1例,
第251回徳島医学会学術集会, 2015年8月. 瀬野弘光, 山﨑宙, 八木秀介, 黒部裕嗣, 高森信行, 楠瀬賢也, 伊勢孝之, 山口浩司, 山田博胤, 添木武, 若槻哲三, 佐田政隆 :
急激な弁破壊を認めたメチシリン感受性表皮ブドウ球菌による感染性心内膜炎の一例,
第251回徳島医学会学術集会, 2015年8月. Takeshi Soeki, T Matsuura, S Bando, E Uematsu, Takayuki Ise, Takeshi Tobiume, Koji Yamaguchi, Shusuke Yagi, Daiju Fukuda, Takashi Iwase, Hirotsugu Yamada, Tetsuzo Wakatsuki, Michio Shimabukuro, I Kishimoto, Kenji Kangawa and Masataka Sata :
Ghrelin protects the heart against ischemia-induced arrhythmia by preserving connexin 43 protein.,
第36回心筋代謝研究会, Jul. 2013. 坂東美佳, 山田博胤, 西尾進, 冨田紀子, 發知淳子, 林修司, 中川摩耶, 玉井利奈, 平田有紀奈, 弘田大智, 小笠原梢, 髙島啓, 山崎宙, 坂東左知子, 伊勢孝之, 仁木敏之, 山口浩司, 岩瀬俊, 竹谷善雄, 添木武, 若槻哲三, 赤池雅史, 佐田政隆 :
質低下療法による頸動脈プラーク安定化の評価,
第5回T0kushima Young Investigators Conference, 2012年3月. 坂東美佳, 山田博胤, 冨田紀子, 發知淳子, 西尾進, 中川摩耶, 玉井利奈, 平田有紀奈, 弘田大智, 坂東左知子, 伊勢孝之, 仁木敏之, 山口浩司, 岩瀬俊, 竹谷善雄, 添木武, 若槻哲三, 佐田政隆 :
Fabry病の2家系,
第16回中四国心筋症・心不全研究会, 2011年9月. 岩瀬俊, 伊勢孝之, 小笠原梢, 山崎宙, 高島啓, 坂東左知子, 仁木敏之, 楠瀬賢也, 發知淳子, 冨田紀子, 上田由佳, 山口浩司, 竹谷善雄, 山田博胤, 添木武, 若槻哲三, 佐田政隆, 髙尾正一郎, 能勢隼人, 原田雅史, 赤池雅史, 足立克仁 :
Duchenne型筋ジストロフィー女性キャリアの心病変検出における心臓MRI検査の有用性,
第16回中四国心筋症・心不全研究会, 2011年9月. 原知也, 岩瀬俊, 高島啓, 山崎宙, 小笠原梢, 坂東左知子, 伊勢孝之, 仁木敏之, 楠瀬賢也, 上田由佳, 冨田紀子, 山口浩司, 竹谷善雄, 山田博胤, 添木武, 若槻哲三, 佐田政隆, 赤池雅史, 能勢隼人, 髙尾正一郎, 大塚秀樹, 原田雅史, 西岡安彦 :
心サルコイドーシス診断の手引きにおける各種診断モダリティーの検討,
第16回中四国心筋症・心不全研究会, 2011年9月. 粟飯原賢一, 東博之, 赤池雅史, 池田康将, 八木秀介, 住友由佳, 吉田守美子, 伊勢孝之, 岩瀬俊, 松本俊夫 :
新規血管リモデリング抑制因子ヘパリンコファクターIIの分子生物学的解析,
第9回四国循環器研究会, 2007年9月. 石井亜由美, 伊勢孝之, 西川幸治, 後藤強, 八木秀介, 加藤真介, 佐田政隆 :
徳島大学病院での心臓リハビリテーションの現状,
心臓リハビリテーション, Vol.19, No.1, 161-162, 2014年2月.

特許: 研究者総覧に該当データはありませんでした。
作品: 八木秀介, 福田大受, 平田有紀奈, GANBAATAR BYAMBASUREN, Arief Rahadian, 伊勢孝之, 楠瀬賢也, 山田博胤, 山口浩司, 松浦朋美, 飛梅威, 曽我朋宏, 添木武, 若槻哲三, 川人伸次, 佐田政隆 :
【糖尿病専門医に必要な心不全の知識update】SGLT2阻害薬と心不全(解説/特集),
糖尿病・内分泌代謝科, Vol.52, No.3, 257-264, 2021年11月.
補助金・競争的資金: Withコロナに対応した高度オンライン臨床実習システムの構築と効果の検証 (研究課題/領域番号: 21K12156 )
代謝リモデリングを標的とした心臓リハビリテーション栄養の実現化 (研究課題/領域番号: 20H04038 )
大動脈瘤形成におけるヘパリンコファクターⅡの臨床的意義および病態分子機構の解明 (研究課題/領域番号: 25860605 )
研究者番号（90621649）による検索

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受賞: 2013年4月, 第24回日本心エコー図学会学術集会海外学会発表優秀論文賞 (日本心エコー図学会)
2013年5月, 第102回日本循環器学会中国・四国合同地方会若手研究者部門最優秀賞 (社団法人日本循環器学会)
2013年5月, 第102回日本循環器学会中国・四国合同地方会研修医部門最優秀賞 (社団法人日本循環器学会)
2013年5月, 第102回日本循環器学会中国・四国合同地方会コメディカル部門最優秀賞 (社団法人日本循環器学会)
2013年9月, 第61回日本心臓病学会学術集会 Case Presentation Award(ポスター) 優秀演題賞 (日本心臓病学会)
2013年10月, 第33回日本サルコイドーシス/肉芽腫性疾患学会総会 Young Investigator's Award 最優秀賞 (日本サルコイドーシス/肉芽腫性疾患学会)
2013年12月, 第103回日本循環器学会四国地方会学生・研修医セッション奨励賞 (社団法人日本循環器学会)
2014年7月, 第248回徳島医学会学術集会(平成25年度冬期)若手奨励賞 (徳島医学会)
2014年7月, 第248回徳島医学会学術集会(平成25年度冬期) 若手奨励賞 (徳島医学会)
2014年12月, 第105回日本循環器学会四国地方会コメディカルセッション奨励賞 (社団法人日本循環器学会)
2015年3月, 平成26年度表彰論文優秀賞 (公益財団法人福田記念医療技術振興財団)
2015年9月, 第63回日本心臓病学会学術集会若手症例Presenter賞 (日本心臓病学会)
2016年3月, 第5回日本循環器学会循環器臨床研究奨励賞(症例報告部門) (社団法人日本循環器学会)
2016年3月, 第3回日本循環器学会循環器イメージング賞 (社団法人日本循環器学会)
2016年6月, 第108回日本循環器学会中国・四国合同地方会「研修医奨励賞」 (日本心臓病学会)
2016年7月, 第253回徳島医学会学術集会(平成28年度夏期)「若手奨励賞」 (徳島医学会)
2016年9月, 第64回日本心臓病学会学術集会優秀演題セッション(医師部門)優秀賞 (日本心臓病学会)
2016年9月, KSC2016 Young Investigator's Award (The 60th Annual Scientific Meeting of The Korean Society of Cardiology)
2016年12月, 第109回日本循環器学会四国地方会学生・研修医奨励賞 (社団法人日本循環器学会)
2017年3月, Young Investigator's Award (Clinical Research ) (社団法人日本循環器学会)
2017年9月, 優秀演題賞 (第24回日本心血管インターベーション治療学会中国・四国地方会)
2017年9月, Young Investigators Award 最優秀賞 (第65回日本心臓病学会学術集会)
2018年9月, Young Investigator's Award (第25回日本心血管インターベンション治療学会中国四国地方会)
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研究者番号: 90621649

所属（現在）: 2024/4/1 : 徳島大学, 病院, 助教

所属（過去の研究課題 情報に基づく）*注記: 2020/4/1 – 2022/4/1 : 徳島大学, 病院, 助教
2015/4/1 : 徳島大学, 大学病院, 助教
2014/4/1 : 徳島大学, 大学病院, 特任助教
2013/4/1 : 徳島大学, 大学病院, 助教

審査区分/研究分野

研究代表者

生物系 / 医歯薬学 / 内科系臨床医学 / 循環器内科学
小区分62030:学習支援システム関連

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小区分59010:リハビリテーション科学関連

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大動脈瘤 / Acute　Aortic　Syndrome / Acute Aortic Symdrome / 学習支援システム / Withコロナ / オンライン / 臨床実習

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代謝リモデリング / 心臓リハビリテーション / リハビリテーション栄養 / 心不全 / エネルギー代謝 / ミトコンドリア機能 / リハ栄養 / 運動耐容能 / 糖・脂質代謝

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伊勢 孝之

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伊勢孝之